Should you encounter any unexpected behaviour,
please let us know.

* CysB *

CA strain for 240125143252356257

--- normal mode 8 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 LYS 2 -0.0000

LYS 2 LEU 3 0.0002

LEU 3 GLN 4 -0.0004

GLN 4 GLN 5 -0.0000

GLN 5 LEU 6 0.0001

LEU 6 ARG 7 0.0001

ARG 7 TYR 8 -0.0000

TYR 8 ILE 9 -0.0003

ILE 9 VAL 10 0.0000

VAL 10 GLU 11 0.0001

GLU 11 VAL 12 0.0000

VAL 12 VAL 13 -0.0003

VAL 13 ASN 14 0.0023

ASN 14 HIS 15 0.0001

HIS 15 ASN 16 0.0003

ASN 16 LEU 17 -0.0002

LEU 17 ASN 18 0.0001

ASN 18 VAL 19 -0.0004

VAL 19 SER 20 -0.0004

SER 20 SER 21 0.0001

SER 21 THR 22 0.0002

THR 22 ALA 23 -0.0003

ALA 23 GLU 24 -0.0000

GLU 24 GLY 25 0.0002

GLY 25 LEU 26 0.0001

LEU 26 TYR 27 0.0021

TYR 27 THR 28 -0.0001

THR 28 SER 29 0.0003

SER 29 GLN 30 -0.0004

GLN 30 PRO 31 0.0001

PRO 31 GLY 32 0.0003

GLY 32 ILE 33 0.0001

ILE 33 SER 34 -0.0001

SER 34 LYS 35 -0.0000

LYS 35 GLN 36 0.0001

GLN 36 VAL 37 -0.0002

VAL 37 ARG 38 -0.0001

ARG 38 MET 39 -0.0002

MET 39 LEU 40 0.0026

LEU 40 GLU 41 0.0001

GLU 41 ASP 42 0.0001

ASP 42 GLU 43 0.0000

GLU 43 LEU 44 -0.0000

LEU 44 GLY 45 0.0001

GLY 45 ILE 46 0.0001

ILE 46 GLN 47 0.0001

GLN 47 ILE 48 0.0001

ILE 48 PHE 49 -0.0003

PHE 49 ALA 50 0.0005

ALA 50 ARG 51 -0.0003

ARG 51 SER 52 -0.0000

SER 52 GLY 53 0.0041

GLY 53 LYS 54 -0.0001

LYS 54 HIS 55 -0.0002

HIS 55 LEU 56 -0.0001

LEU 56 THR 57 0.0000

THR 57 GLN 58 0.0001

GLN 58 VAL 59 -0.0002

VAL 59 THR 60 -0.0000

THR 60 PRO 61 -0.0001

PRO 61 ALA 62 0.0004

ALA 62 GLY 63 0.0001

GLY 63 GLN 64 -0.0000

GLN 64 GLU 65 -0.0002

GLU 65 ILE 66 0.0100

ILE 66 ILE 67 0.0001

ILE 67 ARG 68 -0.0004

ARG 68 ILE 69 0.0001

ILE 69 ALA 70 -0.0001

ALA 70 ARG 71 0.0002

ARG 71 GLU 72 -0.0001

GLU 72 VAL 73 -0.0001

VAL 73 LEU 74 -0.0002

LEU 74 SER 75 -0.0003

SER 75 LYS 76 0.0001

LYS 76 VAL 77 0.0000

VAL 77 ASP 78 -0.0002

ASP 78 ALA 79 0.0120

ALA 79 ILE 80 0.0001

ILE 80 LYS 81 0.0001

LYS 81 SER 82 0.0001

SER 82 VAL 83 0.0000

VAL 83 ALA 84 0.0000

ALA 84 GLY 85 -0.0003

GLY 85 GLU 86 -0.0004

GLU 86 HIS 87 -0.0000

HIS 87 THR 88 0.0001

THR 88 TRP 89 0.0002

TRP 89 PRO 90 -0.0001

PRO 90 ASP 91 0.0001

ASP 91 LYS 92 0.0002

LYS 92 GLY 93 0.0001

GLY 93 SER 94 0.0000

SER 94 LEU 95 -0.0001

LEU 95 TYR 96 -0.0001

TYR 96 VAL 97 -0.0003

VAL 97 ALA 98 -0.0001

ALA 98 THR 99 0.0001

THR 99 THR 100 0.0003

THR 100 HIS 101 -0.0001

HIS 101 THR 102 -0.0001

THR 102 GLN 103 -0.0001

GLN 103 ALA 104 0.0002

ALA 104 ARG 105 -0.0035

ARG 105 TYR 106 -0.0002

TYR 106 ALA 107 -0.0003

ALA 107 LEU 108 -0.0000

LEU 108 PRO 109 0.0001

PRO 109 GLY 110 0.0004

GLY 110 VAL 111 0.0001

VAL 111 ILE 112 -0.0003

ILE 112 LYS 113 0.0003

LYS 113 GLY 114 0.0001

GLY 114 PHE 115 0.0001

PHE 115 ILE 116 0.0001

ILE 116 GLU 117 -0.0000

GLU 117 ARG 118 -0.0059

ARG 118 TYR 119 0.0001

TYR 119 PRO 120 0.0001

PRO 120 ARG 121 -0.0001

ARG 121 VAL 122 -0.0000

VAL 122 SER 123 0.0001

SER 123 LEU 124 0.0002

LEU 124 HIS 125 0.0001

HIS 125 MET 126 -0.0002

MET 126 HIS 127 0.0000

HIS 127 GLN 128 0.0002

GLN 128 GLY 129 0.0001

GLY 129 SER 130 0.0000

SER 130 PRO 131 -0.0020

PRO 131 THR 132 0.0001

THR 132 GLN 133 -0.0001

GLN 133 ILE 134 -0.0003

ILE 134 ALA 135 -0.0002

ALA 135 GLU 136 0.0001

GLU 136 ALA 137 0.0003

ALA 137 VAL 138 -0.0000

VAL 138 SER 139 0.0002

SER 139 LYS 140 0.0004

LYS 140 GLY 141 -0.0000

GLY 141 ASN 142 0.0003

ASN 142 ALA 143 -0.0002

ALA 143 ASP 144 0.0088

ASP 144 PHE 145 -0.0001

PHE 145 ALA 146 0.0002

ALA 146 ILE 147 -0.0001

ILE 147 ALA 148 -0.0002

ALA 148 THR 149 0.0003

THR 149 GLU 150 -0.0002

GLU 150 ALA 151 0.0003

ALA 151 LEU 152 0.0006

LEU 152 HIS 153 -0.0001

HIS 153 LEU 154 0.0000

LEU 154 TYR 155 0.0003

TYR 155 ASP 156 -0.0002

ASP 156 ASP 157 0.0072

ASP 157 LEU 158 -0.0004

LEU 158 VAL 159 0.0002

VAL 159 MET 160 0.0003

MET 160 LEU 161 0.0000

LEU 161 PRO 162 -0.0002

PRO 162 CYS 163 0.0001

CYS 163 TYR 164 -0.0001

TYR 164 HIS 165 0.0002

HIS 165 TRP 166 -0.0002

TRP 166 ASN 167 -0.0003

ASN 167 ARG 168 0.0004

ARG 168 SER 169 -0.0002

SER 169 ILE 170 -0.0136

ILE 170 VAL 171 -0.0004

VAL 171 VAL 172 0.0003

VAL 172 THR 173 -0.0001

THR 173 PRO 174 -0.0003

PRO 174 GLU 175 -0.0005

GLU 175 HIS 176 -0.0001

HIS 176 PRO 177 0.0003

PRO 177 LEU 178 0.0002

LEU 178 ALA 179 0.0000

ALA 179 THR 180 0.0001

THR 180 LYS 181 -0.0003

LYS 181 GLY 182 -0.0000

GLY 182 SER 183 -0.0037

SER 183 VAL 184 0.0002

VAL 184 SER 185 -0.0003

SER 185 ILE 186 0.0003

ILE 186 GLU 187 0.0000

GLU 187 GLU 188 -0.0001

GLU 188 LEU 189 -0.0002

LEU 189 ALA 190 0.0001

ALA 190 GLN 191 -0.0001

GLN 191 GLN 191 -0.0072

GLN 191 TYR 192 0.0002

TYR 192 PRO 193 -0.0000

PRO 193 LEU 194 0.0002

LEU 194 VAL 195 -0.0002

VAL 195 THR 196 -0.0040

THR 196 TYR 197 0.0005

TYR 197 THR 198 -0.0001

THR 198 PHE 199 -0.0004

PHE 199 GLY 200 -0.0003

GLY 200 PHE 201 -0.0003

PHE 201 THR 202 0.0003

THR 202 GLY 203 -0.0001

GLY 203 ARG 204 -0.0003

ARG 204 SER 205 0.0002

SER 205 GLU 206 -0.0003

GLU 206 LEU 207 0.0003

LEU 207 ASP 208 -0.0001

ASP 208 THR 209 -0.0004

THR 209 ALA 210 0.0007

ALA 210 PHE 211 -0.0002

PHE 211 ASN 212 -0.0002

ASN 212 ARG 213 -0.0002

ARG 213 ALA 214 0.0003

ALA 214 GLY 215 -0.0000

GLY 215 LEU 216 -0.0001

LEU 216 THR 217 -0.0001

THR 217 PRO 218 -0.0000

PRO 218 ARG 219 0.0001

ARG 219 ILE 220 -0.0002

ILE 220 VAL 221 0.0001

VAL 221 PHE 222 0.0038

PHE 222 THR 223 -0.0003

THR 223 ALA 224 0.0000

ALA 224 THR 225 0.0001

THR 225 ASP 226 0.0003

ASP 226 ALA 227 -0.0003

ALA 227 ASP 228 0.0000

ASP 228 VAL 229 -0.0004

VAL 229 ILE 230 -0.0000

ILE 230 LYS 231 -0.0000

LYS 231 THR 232 0.0000

THR 232 TYR 233 -0.0004

TYR 233 VAL 234 0.0001

VAL 234 ARG 235 0.0017

ARG 235 LEU 236 -0.0003

LEU 236 GLY 237 0.0004

GLY 237 LEU 238 0.0003

LEU 238 GLY 239 -0.0000

GLY 239 VAL 240 -0.0000

VAL 240 GLY 241 -0.0001

GLY 241 VAL 242 0.0001

VAL 242 ILE 243 -0.0001

ILE 243 ALA 244 0.0002

ALA 244 SER 245 -0.0004

SER 245 MET 246 -0.0002

MET 246 ALA 247 -0.0003

ALA 247 VAL 248 -0.0080

VAL 248 ASP 249 -0.0002

ASP 249 PRO 250 0.0003

PRO 250 VAL 251 -0.0001

VAL 251 SER 252 0.0003

SER 252 ASP 253 0.0001

ASP 253 PRO 254 0.0001

PRO 254 ASP 255 0.0001

ASP 255 LEU 256 -0.0001

LEU 256 VAL 257 0.0002

VAL 257 LYS 258 0.0000

LYS 258 LEU 259 -0.0001

LEU 259 ASP 260 0.0002

ASP 260 ALA 261 -0.0119

ALA 261 ASN 262 -0.0002

ASN 262 GLY 263 0.0000

GLY 263 ILE 264 0.0002

ILE 264 PHE 265 -0.0005

PHE 265 SER 266 0.0002

SER 266 HIS 267 0.0000

HIS 267 SER 268 0.0002

SER 268 THR 269 0.0000

THR 269 THR 270 -0.0003

THR 270 LYS 271 0.0002

LYS 271 ILE 272 -0.0002

ILE 272 GLY 273 0.0001

GLY 273 PHE 274 -0.0031

PHE 274 ARG 275 0.0001

ARG 275 ARG 276 -0.0001

ARG 276 SER 277 0.0001

SER 277 THR 278 -0.0004

THR 278 PHE 279 0.0004

PHE 279 LEU 280 -0.0003

LEU 280 ARG 281 -0.0000

ARG 281 SER 282 0.0000

SER 282 TYR 283 0.0001

TYR 283 MET 284 -0.0001

MET 284 TYR 285 0.0003

TYR 285 ASP 286 0.0000

ASP 286 PHE 287 -0.0003

PHE 287 ILE 288 -0.0001

ILE 288 GLN 289 0.0002

GLN 289 ARG 290 0.0001

ARG 290 PHE 291 -0.0001

PHE 291 ALA 292 -0.0003

ALA 292 PRO 293 0.0000

PRO 293 HIS 294 0.0003

HIS 294 LEU 295 0.0003

LEU 295 THR 296 -0.0004

THR 296 ARG 297 0.0002

ARG 297 ASP 298 0.0001

ASP 298 VAL 299 -0.0003

VAL 299 VAL 300 0.0016

VAL 300 ASP 301 0.0001

ASP 301 THR 302 0.0000

THR 302 ALA 303 0.0001

ALA 303 VAL 304 -0.0001

VAL 304 ALA 305 -0.0002

ALA 305 LEU 306 -0.0001

LEU 306 ARG 307 -0.0003

ARG 307 SER 308 0.0001

SER 308 ASN 309 0.0000

ASN 309 GLU 310 -0.0001

GLU 310 ASP 311 -0.0003

ASP 311 ILE 312 0.0001

ILE 312 GLU 313 -0.0011

GLU 313 ALA 314 0.0003

ALA 314 MET 315 -0.0005

MET 315 PHE 316 0.0002

PHE 316 LYS 317 -0.0002

LYS 317 ASP 318 0.0000

ASP 318 ILE 319 0.0003

ILE 319 LYS 320 0.0000

LYS 320 LEU 321 0.0000

LEU 321 PRO 322 -0.0002

PRO 322 GLU 323 0.0002

GLU 323 LYS 324 -0.0003

LYS 324 MET 1 -0.0028

MET 1 LYS 2 -0.0000

LYS 2 LEU 3 -0.0000

LEU 3 GLN 4 0.0001

GLN 4 GLN 5 0.0003

GLN 5 LEU 6 -0.0001

LEU 6 ARG 7 -0.0000

ARG 7 TYR 8 0.0002

TYR 8 ILE 9 0.0001

ILE 9 VAL 10 0.0001

VAL 10 GLU 11 -0.0002

GLU 11 VAL 12 -0.0001

VAL 12 VAL 13 -0.0000

VAL 13 ASN 14 0.0152

ASN 14 HIS 15 0.0001

HIS 15 ASN 16 -0.0003

ASN 16 LEU 17 0.0000

LEU 17 ASN 18 0.0002

ASN 18 VAL 19 0.0003

VAL 19 SER 20 -0.0001

SER 20 SER 21 -0.0001

SER 21 THR 22 -0.0005

THR 22 ALA 23 0.0003

ALA 23 GLU 24 -0.0001

GLU 24 GLY 25 0.0004

GLY 25 LEU 26 -0.0001

LEU 26 TYR 27 0.0011

TYR 27 THR 28 0.0002

THR 28 SER 29 0.0000

SER 29 GLN 30 -0.0004

GLN 30 PRO 31 0.0002

PRO 31 GLY 32 -0.0001

GLY 32 ILE 33 -0.0000

ILE 33 SER 34 0.0003

SER 34 LYS 35 -0.0000

LYS 35 GLN 36 -0.0002

GLN 36 VAL 37 -0.0003

VAL 37 ARG 38 -0.0002

ARG 38 MET 39 -0.0004

MET 39 LEU 40 0.0062

LEU 40 GLU 41 0.0001

GLU 41 ASP 42 -0.0000

ASP 42 GLU 43 0.0003

GLU 43 LEU 44 0.0002

LEU 44 GLY 45 0.0002

GLY 45 ILE 46 0.0000

ILE 46 GLN 47 0.0004

GLN 47 ILE 48 -0.0002

ILE 48 PHE 49 0.0002

PHE 49 ALA 50 -0.0000

ALA 50 ARG 51 -0.0002

ARG 51 SER 52 -0.0002

SER 52 GLY 53 0.0104

GLY 53 LYS 54 0.0001

LYS 54 HIS 55 -0.0003

HIS 55 LEU 56 -0.0004

LEU 56 THR 57 0.0000

THR 57 GLN 58 0.0001

GLN 58 VAL 59 0.0000

VAL 59 THR 60 0.0002

THR 60 PRO 61 0.0000

PRO 61 ALA 62 0.0000

ALA 62 GLY 63 0.0001

GLY 63 GLN 64 -0.0003

GLN 64 GLU 65 -0.0000

GLU 65 ILE 66 0.0003

ILE 66 ILE 67 0.0004

ILE 67 ARG 68 0.0002

ARG 68 ILE 69 -0.0004

ILE 69 ALA 70 0.0001

ALA 70 ARG 71 -0.0001

ARG 71 GLU 72 -0.0001

GLU 72 VAL 73 -0.0000

VAL 73 LEU 74 -0.0004

LEU 74 SER 75 0.0000

SER 75 LYS 76 -0.0004

LYS 76 VAL 77 -0.0000

VAL 77 ASP 78 -0.0000

ASP 78 ALA 79 -0.0181

ALA 79 ILE 80 0.0000

ILE 80 LYS 81 -0.0000

LYS 81 SER 82 0.0003

SER 82 VAL 83 0.0003

VAL 83 ALA 84 -0.0001

ALA 84 GLY 85 -0.0002

GLY 85 GLU 86 -0.0003

GLU 86 HIS 87 -0.0002

HIS 87 THR 88 -0.0001

THR 88 TRP 89 0.0002

TRP 89 PRO 90 0.0002

PRO 90 ASP 91 -0.0000

ASP 91 LYS 92 0.0199

LYS 92 GLY 93 -0.0001

GLY 93 SER 94 0.0002

SER 94 LEU 95 -0.0003

LEU 95 TYR 96 0.0005

TYR 96 VAL 97 -0.0003

VAL 97 ALA 98 0.0002

ALA 98 THR 99 -0.0002

THR 99 THR 100 -0.0002

THR 100 HIS 101 -0.0000

HIS 101 THR 102 0.0000

THR 102 GLN 103 0.0002

GLN 103 ALA 104 0.0001

ALA 104 ARG 105 -0.0002

ARG 105 TYR 106 -0.0000

TYR 106 ALA 107 -0.0002

ALA 107 LEU 108 0.0000

LEU 108 PRO 109 0.0001

PRO 109 GLY 110 -0.0001

GLY 110 VAL 111 -0.0004

VAL 111 ILE 112 0.0001

ILE 112 LYS 113 0.0000

LYS 113 GLY 114 -0.0001

GLY 114 PHE 115 0.0004

PHE 115 ILE 116 -0.0004

ILE 116 GLU 117 0.0000

GLU 117 ARG 118 -0.0006

ARG 118 TYR 119 -0.0001

TYR 119 PRO 120 0.0002

PRO 120 ARG 121 -0.0003

ARG 121 VAL 122 -0.0002

VAL 122 SER 123 0.0002

SER 123 LEU 124 -0.0002

LEU 124 HIS 125 -0.0001

HIS 125 MET 126 -0.0000

MET 126 HIS 127 -0.0002

HIS 127 GLN 128 -0.0001

GLN 128 GLY 129 0.0004

GLY 129 SER 130 0.0001

SER 130 PRO 131 0.0007

PRO 131 THR 132 -0.0000

THR 132 GLN 133 -0.0002

GLN 133 ILE 134 -0.0001

ILE 134 ALA 135 -0.0000

ALA 135 GLU 136 -0.0003

GLU 136 ALA 137 0.0002

ALA 137 VAL 138 0.0002

VAL 138 SER 139 0.0004

SER 139 LYS 140 0.0002

LYS 140 GLY 141 0.0003

GLY 141 ASN 142 0.0001

ASN 142 ALA 143 0.0002

ALA 143 ASP 144 -0.0049

ASP 144 PHE 145 -0.0001

PHE 145 ALA 146 0.0001

ALA 146 ILE 147 0.0004

ILE 147 ALA 148 -0.0002

ALA 148 THR 149 -0.0004

THR 149 GLU 150 -0.0000

GLU 150 ALA 151 0.0002

ALA 151 LEU 152 -0.0000

LEU 152 HIS 153 0.0001

HIS 153 LEU 154 0.0001

LEU 154 TYR 155 0.0001

TYR 155 ASP 156 -0.0000

ASP 156 ASP 157 -0.0006

ASP 157 LEU 158 0.0003

LEU 158 VAL 159 0.0001

VAL 159 MET 160 0.0001

MET 160 LEU 161 0.0003

LEU 161 PRO 162 0.0001

PRO 162 CYS 163 -0.0001

CYS 163 TYR 164 -0.0002

TYR 164 HIS 165 -0.0001

HIS 165 TRP 166 0.0000

TRP 166 ASN 167 -0.0002

ASN 167 ARG 168 0.0001

ARG 168 SER 169 0.0004

SER 169 ILE 170 -0.0006

ILE 170 VAL 171 0.0000

VAL 171 VAL 172 0.0002

VAL 172 THR 173 -0.0005

THR 173 PRO 174 -0.0002

PRO 174 GLU 175 0.0000

GLU 175 HIS 176 0.0001

HIS 176 PRO 177 0.0003

PRO 177 LEU 178 0.0001

LEU 178 ALA 179 0.0004

ALA 179 THR 180 -0.0002

THR 180 LYS 181 0.0000

LYS 181 GLY 182 -0.0001

GLY 182 SER 183 0.0006

SER 183 VAL 184 0.0004

VAL 184 SER 185 -0.0001

SER 185 ILE 186 -0.0001

ILE 186 GLU 187 0.0002

GLU 187 GLU 188 -0.0001

GLU 188 LEU 189 -0.0001

LEU 189 ALA 190 -0.0003

ALA 190 GLN 191 0.0001

GLN 191 TYR 192 -0.0006

TYR 192 PRO 193 -0.0002

PRO 193 LEU 194 0.0000

LEU 194 VAL 195 -0.0002

VAL 195 THR 196 0.0008

THR 196 TYR 197 -0.0001

TYR 197 THR 198 -0.0001

THR 198 PHE 199 -0.0001

PHE 199 GLY 200 -0.0003

GLY 200 PHE 201 0.0000

PHE 201 THR 202 -0.0003

THR 202 GLY 203 -0.0002

GLY 203 ARG 204 0.0000

ARG 204 SER 205 -0.0000

SER 205 GLU 206 0.0004

GLU 206 LEU 207 -0.0002

LEU 207 ASP 208 0.0001

ASP 208 THR 209 -0.0030

THR 209 ALA 210 -0.0003

ALA 210 PHE 211 -0.0005

PHE 211 ASN 212 0.0002

ASN 212 ARG 213 -0.0001

ARG 213 ALA 214 0.0001

ALA 214 GLY 215 0.0001

GLY 215 LEU 216 0.0003

LEU 216 THR 217 -0.0005

THR 217 PRO 218 0.0002

PRO 218 ARG 219 0.0000

ARG 219 ILE 220 0.0002

ILE 220 VAL 221 -0.0007

VAL 221 PHE 222 0.0002

PHE 222 THR 223 -0.0002

THR 223 ALA 224 0.0002

ALA 224 THR 225 0.0003

THR 225 ASP 226 -0.0001

ASP 226 ALA 227 -0.0001

ALA 227 ASP 228 0.0001

ASP 228 VAL 229 0.0003

VAL 229 ILE 230 0.0000

ILE 230 LYS 231 -0.0000

LYS 231 THR 232 -0.0001

THR 232 TYR 233 -0.0001

TYR 233 VAL 234 -0.0002

VAL 234 ARG 235 -0.0012

ARG 235 LEU 236 -0.0000

LEU 236 GLY 237 0.0001

GLY 237 LEU 238 0.0001

LEU 238 GLY 239 0.0003

GLY 239 VAL 240 0.0001

VAL 240 GLY 241 0.0003

GLY 241 VAL 242 -0.0000

VAL 242 ILE 243 0.0003

ILE 243 ALA 244 0.0002

ALA 244 SER 245 0.0003

SER 245 MET 246 -0.0002

MET 246 ALA 247 -0.0003

ALA 247 VAL 248 -0.0007

VAL 248 ASP 249 -0.0005

ASP 249 PRO 250 0.0001

PRO 250 VAL 251 -0.0001

VAL 251 SER 252 0.0001

SER 252 ASP 253 -0.0000

ASP 253 PRO 254 -0.0003

PRO 254 ASP 255 -0.0003

ASP 255 LEU 256 -0.0001

LEU 256 VAL 257 -0.0001

VAL 257 LYS 258 -0.0003

LYS 258 LEU 259 0.0004

LEU 259 ASP 260 0.0001

ASP 260 ALA 261 0.0010

ALA 261 ASN 262 0.0001

ASN 262 GLY 263 -0.0003

GLY 263 ILE 264 0.0002

ILE 264 PHE 265 -0.0005

PHE 265 SER 266 0.0001

SER 266 HIS 267 -0.0000

HIS 267 SER 268 -0.0000

SER 268 THR 269 -0.0000

THR 269 THR 270 0.0001

THR 270 LYS 271 -0.0002

LYS 271 ILE 272 -0.0001

ILE 272 GLY 273 0.0001

GLY 273 PHE 274 -0.0020

PHE 274 ARG 275 0.0004

ARG 275 ARG 276 0.0001

ARG 276 SER 277 0.0001

SER 277 THR 278 0.0001

THR 278 PHE 279 0.0004

PHE 279 LEU 280 0.0002

LEU 280 ARG 281 -0.0000

ARG 281 SER 282 -0.0001

SER 282 TYR 283 0.0001

TYR 283 MET 284 0.0002

MET 284 TYR 285 -0.0001

TYR 285 ASP 286 0.0002

ASP 286 PHE 287 -0.0002

PHE 287 ILE 288 -0.0001

ILE 288 GLN 289 -0.0001

GLN 289 ARG 290 0.0001

ARG 290 PHE 291 0.0002

PHE 291 ALA 292 0.0001

ALA 292 PRO 293 -0.0002

PRO 293 HIS 294 0.0002

HIS 294 LEU 295 -0.0002

LEU 295 THR 296 0.0002

THR 296 ARG 297 0.0001

ARG 297 ASP 298 -0.0002

ASP 298 VAL 299 0.0001

VAL 299 VAL 300 0.0015

VAL 300 ASP 301 0.0005

ASP 301 THR 302 0.0004

THR 302 ALA 303 0.0002

ALA 303 VAL 304 0.0001

VAL 304 ALA 305 0.0001

ALA 305 LEU 306 -0.0003

LEU 306 ARG 307 -0.0001

ARG 307 SER 308 -0.0002

SER 308 ASN 309 -0.0001

ASN 309 GLU 310 -0.0004

GLU 310 ASP 311 -0.0001

ASP 311 ILE 312 -0.0001

ILE 312 GLU 313 0.0000

GLU 313 ALA 314 0.0003

ALA 314 MET 315 0.0000

MET 315 PHE 316 0.0003

PHE 316 LYS 317 0.0002

LYS 317 ASP 318 0.0002

ASP 318 ILE 319 -0.0001

ILE 319 LYS 320 -0.0000

LYS 320 LEU 321 0.0000

LEU 321 PRO 322 0.0000

PRO 322 GLU 323 -0.0002

GLU 323 LYS 324 -0.0001

LYS 324 MET 1 -0.0097

MET 1 LYS 2 -0.0003

LYS 2 LEU 3 0.0003

LEU 3 GLN 4 0.0003

GLN 4 GLN 5 0.0002

GLN 5 LEU 6 -0.0003

LEU 6 ARG 7 0.0003

ARG 7 TYR 8 -0.0002

TYR 8 ILE 9 -0.0000

ILE 9 VAL 10 -0.0000

VAL 10 GLU 11 -0.0002

GLU 11 VAL 12 -0.0000

VAL 12 VAL 13 -0.0004

VAL 13 ASN 14 0.0003

ASN 14 HIS 15 0.0000

HIS 15 ASN 16 0.0000

ASN 16 LEU 17 -0.0001

LEU 17 ASN 18 -0.0000

ASN 18 VAL 19 0.0003

VAL 19 SER 20 0.0002

SER 20 SER 21 -0.0001

SER 21 THR 22 0.0002

THR 22 ALA 23 -0.0001

ALA 23 GLU 24 0.0002

GLU 24 GLY 25 -0.0002

GLY 25 LEU 26 0.0002

LEU 26 TYR 27 0.0031

TYR 27 THR 28 -0.0004

THR 28 SER 29 0.0004

SER 29 GLN 30 -0.0002

GLN 30 PRO 31 -0.0000

PRO 31 GLY 32 0.0001

GLY 32 ILE 33 -0.0001

ILE 33 SER 34 -0.0002

SER 34 LYS 35 0.0000

LYS 35 GLN 36 0.0001

GLN 36 VAL 37 0.0001

VAL 37 ARG 38 0.0000

ARG 38 MET 39 0.0002

MET 39 LEU 40 -0.0013

LEU 40 GLU 41 -0.0004

GLU 41 ASP 42 0.0001

ASP 42 GLU 43 0.0003

GLU 43 LEU 44 -0.0002

LEU 44 GLY 45 0.0001

GLY 45 ILE 46 0.0005

ILE 46 GLN 47 -0.0004

GLN 47 ILE 48 -0.0001

ILE 48 PHE 49 -0.0005

PHE 49 ALA 50 -0.0000

ALA 50 ARG 51 0.0001

ARG 51 SER 52 -0.0000

SER 52 GLY 53 -0.0004

GLY 53 LYS 54 0.0001

LYS 54 HIS 55 0.0001

HIS 55 LEU 56 0.0002

LEU 56 THR 57 -0.0001

THR 57 GLN 58 0.0002

GLN 58 VAL 59 -0.0001

VAL 59 THR 60 0.0000

THR 60 PRO 61 -0.0001

PRO 61 ALA 62 -0.0005

ALA 62 GLY 63 -0.0002

GLY 63 GLN 64 -0.0001

GLN 64 GLU 65 -0.0002

GLU 65 ILE 66 0.0035

ILE 66 ILE 67 0.0003

ILE 67 ARG 68 0.0000

ARG 68 ILE 69 0.0005

ILE 69 ALA 70 -0.0001

ALA 70 ARG 71 0.0002

ARG 71 GLU 72 -0.0001

GLU 72 VAL 73 -0.0002

VAL 73 LEU 74 -0.0002

LEU 74 SER 75 0.0002

SER 75 LYS 76 0.0002

LYS 76 VAL 77 0.0002

VAL 77 ASP 78 -0.0002

ASP 78 ALA 79 0.0247

ALA 79 ILE 80 -0.0003

ILE 80 LYS 81 0.0002

LYS 81 SER 82 -0.0001

SER 82 VAL 83 -0.0001

VAL 83 ALA 84 -0.0002

ALA 84 GLY 85 -0.0000

GLY 85 GLU 86 -0.0000

GLU 86 HIS 87 -0.0003

HIS 87 THR 88 -0.0002

THR 88 TRP 89 0.0002

TRP 89 PRO 90 -0.0003

PRO 90 ASP 91 -0.0001

ASP 91 LYS 92 0.0161

LYS 92 GLY 93 0.0004

GLY 93 SER 94 -0.0000

SER 94 LEU 95 0.0001

LEU 95 TYR 96 -0.0000

TYR 96 VAL 97 -0.0004

VAL 97 ALA 98 -0.0000

ALA 98 THR 99 0.0002

THR 99 THR 100 0.0003

THR 100 HIS 101 -0.0002

HIS 101 THR 102 -0.0002

THR 102 GLN 103 -0.0003

GLN 103 ALA 104 -0.0002

ALA 104 ARG 105 -0.0006

ARG 105 TYR 106 0.0000

TYR 106 ALA 107 -0.0001

ALA 107 LEU 108 -0.0001

LEU 108 PRO 109 -0.0000

PRO 109 GLY 110 0.0001

GLY 110 VAL 111 0.0002

VAL 111 ILE 112 0.0001

ILE 112 LYS 113 0.0002

LYS 113 GLY 114 -0.0005

GLY 114 PHE 115 -0.0000

PHE 115 ILE 116 -0.0001

ILE 116 GLU 117 -0.0002

GLU 117 ARG 118 0.0001

ARG 118 TYR 119 0.0001

TYR 119 PRO 120 -0.0002

PRO 120 ARG 121 -0.0001

ARG 121 VAL 122 0.0003

VAL 122 SER 123 -0.0001

SER 123 LEU 124 0.0003

LEU 124 HIS 125 0.0003

HIS 125 MET 126 -0.0001

MET 126 HIS 127 0.0002

HIS 127 GLN 128 -0.0002

GLN 128 GLY 129 0.0004

GLY 129 SER 130 -0.0001

SER 130 PRO 131 0.0006

PRO 131 THR 132 -0.0003

THR 132 GLN 133 -0.0001

GLN 133 ILE 134 0.0003

ILE 134 ALA 135 -0.0000

ALA 135 GLU 136 0.0002

GLU 136 ALA 137 0.0001

ALA 137 VAL 138 -0.0002

VAL 138 SER 139 0.0001

SER 139 LYS 140 0.0000

LYS 140 GLY 141 -0.0002

GLY 141 ASN 142 -0.0000

ASN 142 ALA 143 0.0003

ALA 143 ASP 144 -0.0038

ASP 144 PHE 145 -0.0000

PHE 145 ALA 146 0.0002

ALA 146 ILE 147 0.0003

ILE 147 ALA 148 0.0000

ALA 148 THR 149 -0.0001

THR 149 GLU 150 -0.0002

GLU 150 ALA 151 -0.0001

ALA 151 LEU 152 0.0001

LEU 152 HIS 153 0.0003

HIS 153 LEU 154 0.0002

LEU 154 TYR 155 -0.0003

TYR 155 ASP 156 0.0004

ASP 156 ASP 157 -0.0021

ASP 157 LEU 158 -0.0004

LEU 158 VAL 159 0.0003

VAL 159 MET 160 -0.0000

MET 160 LEU 161 0.0004

LEU 161 PRO 162 -0.0000

PRO 162 CYS 163 -0.0003

CYS 163 TYR 164 -0.0002

TYR 164 HIS 165 -0.0001

HIS 165 TRP 166 0.0001

TRP 166 ASN 167 -0.0003

ASN 167 ARG 168 0.0003

ARG 168 SER 169 -0.0001

SER 169 ILE 170 -0.0005

ILE 170 VAL 171 0.0003

VAL 171 VAL 172 0.0003

VAL 172 THR 173 -0.0001

THR 173 PRO 174 -0.0001

PRO 174 GLU 175 0.0004

GLU 175 HIS 176 -0.0001

HIS 176 PRO 177 0.0004

PRO 177 LEU 178 0.0000

LEU 178 ALA 179 -0.0001

ALA 179 THR 180 -0.0001

THR 180 LYS 181 -0.0001

LYS 181 GLY 182 0.0003

GLY 182 SER 183 0.0020

SER 183 VAL 184 0.0000

VAL 184 SER 185 0.0000

SER 185 ILE 186 -0.0003

ILE 186 GLU 187 -0.0001

GLU 187 GLU 188 -0.0003

GLU 188 LEU 189 0.0002

LEU 189 ALA 190 0.0004

ALA 190 GLN 191 -0.0002

GLN 191 TYR 192 0.0000

TYR 192 PRO 193 0.0002

PRO 193 LEU 194 0.0000

LEU 194 VAL 195 -0.0002

VAL 195 THR 196 -0.0004

THR 196 TYR 197 0.0002

TYR 197 THR 198 0.0001

THR 198 PHE 199 0.0001

PHE 199 GLY 200 -0.0002

GLY 200 PHE 201 0.0001

PHE 201 THR 202 0.0000

THR 202 GLY 203 0.0002

GLY 203 ARG 204 0.0002

ARG 204 SER 205 0.0000

SER 205 GLU 206 -0.0003

GLU 206 LEU 207 -0.0000

LEU 207 ASP 208 0.0004

ASP 208 THR 209 0.0014

THR 209 ALA 210 0.0000

ALA 210 PHE 211 -0.0001

PHE 211 ASN 212 0.0000

ASN 212 ARG 213 -0.0003

ARG 213 ALA 214 0.0000

ALA 214 GLY 215 -0.0002

GLY 215 LEU 216 -0.0000

LEU 216 THR 217 -0.0001

THR 217 PRO 218 -0.0001

PRO 218 ARG 219 -0.0000

ARG 219 ILE 220 0.0000

ILE 220 VAL 221 -0.0003

VAL 221 PHE 222 -0.0005

PHE 222 THR 223 -0.0001

THR 223 ALA 224 0.0002

ALA 224 THR 225 0.0002

THR 225 ASP 226 0.0001

ASP 226 ALA 227 -0.0000

ALA 227 ASP 228 -0.0002

ASP 228 VAL 229 -0.0000

VAL 229 ILE 230 -0.0003

ILE 230 LYS 231 0.0001

LYS 231 THR 232 -0.0005

THR 232 TYR 233 0.0001

TYR 233 VAL 234 -0.0002

VAL 234 ARG 235 0.0031

ARG 235 LEU 236 0.0000

LEU 236 GLY 237 0.0000

GLY 237 LEU 238 -0.0001

LEU 238 GLY 239 0.0003

GLY 239 VAL 240 -0.0001

VAL 240 GLY 241 -0.0002

GLY 241 VAL 242 -0.0000

VAL 242 ILE 243 -0.0001

ILE 243 ALA 244 0.0001

ALA 244 SER 245 -0.0002

SER 245 MET 246 -0.0002

MET 246 ALA 247 -0.0000

ALA 247 VAL 248 0.0000

VAL 248 ASP 249 0.0002

ASP 249 PRO 250 0.0003

PRO 250 VAL 251 0.0002

VAL 251 SER 252 -0.0003

SER 252 ASP 253 0.0002

ASP 253 PRO 254 -0.0000

PRO 254 ASP 255 0.0001

ASP 255 LEU 256 0.0001

LEU 256 VAL 257 0.0001

VAL 257 LYS 258 -0.0003

LYS 258 LEU 259 0.0003

LEU 259 ASP 260 -0.0002

ASP 260 ALA 261 0.0023

ALA 261 ASN 262 -0.0002

ASN 262 GLY 263 -0.0001

GLY 263 ILE 264 0.0001

ILE 264 PHE 265 -0.0001

PHE 265 SER 266 -0.0001

SER 266 HIS 267 0.0001

HIS 267 SER 268 0.0002

SER 268 THR 269 -0.0000

THR 269 THR 270 0.0000

THR 270 LYS 271 0.0002

LYS 271 ILE 272 0.0001

ILE 272 GLY 273 -0.0002

GLY 273 PHE 274 -0.0009

PHE 274 ARG 275 -0.0003

ARG 275 ARG 276 -0.0003

ARG 276 SER 277 -0.0003

SER 277 THR 278 -0.0001

THR 278 PHE 279 0.0000

PHE 279 LEU 280 0.0001

LEU 280 ARG 281 0.0001

ARG 281 SER 282 0.0003

SER 282 TYR 283 -0.0003

TYR 283 MET 284 -0.0002

MET 284 TYR 285 0.0002

TYR 285 ASP 286 -0.0000

ASP 286 PHE 287 0.0005

PHE 287 ILE 288 0.0003

ILE 288 GLN 289 -0.0003

GLN 289 ARG 290 -0.0002

ARG 290 PHE 291 0.0001

PHE 291 ALA 292 -0.0002

ALA 292 PRO 293 0.0003

PRO 293 HIS 294 -0.0001

HIS 294 LEU 295 0.0001

LEU 295 THR 296 0.0000

THR 296 ARG 297 -0.0001

ARG 297 ASP 298 0.0001

ASP 298 VAL 299 -0.0002

VAL 299 VAL 300 0.0008

VAL 300 ASP 301 -0.0000

ASP 301 THR 302 0.0003

THR 302 ALA 303 0.0001

ALA 303 VAL 304 0.0001

VAL 304 ALA 305 -0.0002

ALA 305 LEU 306 -0.0005

LEU 306 ARG 307 0.0003

ARG 307 SER 308 0.0002

SER 308 ASN 309 -0.0000

ASN 309 GLU 310 0.0005

GLU 310 ASP 311 -0.0001

ASP 311 ILE 312 -0.0001

ILE 312 GLU 313 -0.0003

GLU 313 ALA 314 0.0003

ALA 314 MET 315 -0.0001

MET 315 PHE 316 -0.0001

PHE 316 LYS 317 0.0001

LYS 317 ASP 318 -0.0003

ASP 318 ILE 319 -0.0002

ILE 319 LYS 320 -0.0002

LYS 320 LEU 321 0.0001

LEU 321 PRO 322 -0.0003

PRO 322 GLU 323 -0.0001

GLU 323 LYS 324 -0.0000

LYS 324 MET 1 0.0002

MET 1 LYS 2 0.0002

LYS 2 LEU 3 -0.0003

LEU 3 GLN 4 0.0002

GLN 4 GLN 5 0.0002

GLN 5 LEU 6 0.0001

LEU 6 ARG 7 0.0001

ARG 7 TYR 8 -0.0001

TYR 8 ILE 9 -0.0000

ILE 9 VAL 10 0.0002

VAL 10 GLU 11 -0.0002

GLU 11 VAL 12 0.0001

VAL 12 VAL 13 0.0002

VAL 13 ASN 14 -0.0016

ASN 14 HIS 15 0.0002

HIS 15 ASN 16 -0.0000

ASN 16 LEU 17 0.0001

LEU 17 ASN 18 0.0000

ASN 18 VAL 19 0.0002

VAL 19 SER 20 0.0002

SER 20 SER 21 -0.0004

SER 21 THR 22 -0.0002

THR 22 ALA 23 0.0002

ALA 23 GLU 24 0.0002

GLU 24 GLY 25 0.0002

GLY 25 LEU 26 0.0003

LEU 26 TYR 27 0.0024

TYR 27 THR 28 -0.0004

THR 28 SER 29 0.0001

SER 29 GLN 30 -0.0002

GLN 30 PRO 31 0.0002

PRO 31 GLY 32 0.0002

GLY 32 ILE 33 -0.0002

ILE 33 SER 34 0.0001

SER 34 LYS 35 -0.0001

LYS 35 GLN 36 0.0004

GLN 36 VAL 37 -0.0004

VAL 37 ARG 38 0.0003

ARG 38 MET 39 0.0000

MET 39 LEU 40 0.0011

LEU 40 GLU 41 -0.0002

GLU 41 ASP 42 0.0002

ASP 42 GLU 43 0.0000

GLU 43 LEU 44 -0.0002

LEU 44 GLY 45 -0.0002

GLY 45 ILE 46 0.0006

ILE 46 GLN 47 -0.0004

GLN 47 ILE 48 -0.0000

ILE 48 PHE 49 0.0001

PHE 49 ALA 50 -0.0001

ALA 50 ARG 51 0.0002

ARG 51 SER 52 -0.0002

SER 52 GLY 53 0.0039

GLY 53 LYS 54 0.0002

LYS 54 HIS 55 -0.0003

HIS 55 LEU 56 0.0002

LEU 56 THR 57 0.0002

THR 57 GLN 58 0.0005

GLN 58 VAL 59 -0.0002

VAL 59 THR 60 0.0001

THR 60 PRO 61 -0.0001

PRO 61 ALA 62 0.0002

ALA 62 GLY 63 -0.0003

GLY 63 GLN 64 0.0001

GLN 64 GLU 65 -0.0003

GLU 65 ILE 66 0.0025

ILE 66 ILE 67 0.0002

ILE 67 ARG 68 0.0001

ARG 68 ILE 69 -0.0001

ILE 69 ALA 70 -0.0002

ALA 70 ARG 71 0.0002

ARG 71 GLU 72 -0.0001

GLU 72 VAL 73 -0.0001

VAL 73 LEU 74 0.0001

LEU 74 SER 75 0.0002

SER 75 LYS 76 0.0001

LYS 76 VAL 77 0.0003

VAL 77 ASP 78 0.0004

ASP 78 ALA 79 0.0126

ALA 79 ILE 80 -0.0001

ILE 80 LYS 81 -0.0003

LYS 81 SER 82 0.0003

SER 82 VAL 83 0.0002

VAL 83 ALA 84 -0.0001

ALA 84 GLY 85 -0.0006

GLY 85 GLU 86 -0.0001

GLU 86 HIS 87 0.0001

HIS 87 THR 88 -0.0002

THR 88 TRP 89 0.0001

TRP 89 PRO 90 -0.0003

PRO 90 ASP 91 0.0000

ASP 91 LYS 92 -0.0031

LYS 92 GLY 93 0.0003

GLY 93 SER 94 0.0001

SER 94 LEU 95 -0.0003

LEU 95 TYR 96 0.0003

TYR 96 VAL 97 -0.0000

VAL 97 ALA 98 -0.0001

ALA 98 THR 99 0.0003

THR 99 THR 100 -0.0002

THR 100 HIS 101 -0.0002

HIS 101 THR 102 -0.0001

THR 102 GLN 103 0.0002

GLN 103 ALA 104 0.0002

ALA 104 ARG 105 0.0026

ARG 105 TYR 106 0.0004

TYR 106 ALA 107 -0.0002

ALA 107 LEU 108 0.0002

LEU 108 PRO 109 0.0004

PRO 109 GLY 110 0.0001

GLY 110 VAL 111 -0.0002

VAL 111 ILE 112 -0.0004

ILE 112 LYS 113 -0.0001

LYS 113 GLY 114 -0.0003

GLY 114 PHE 115 -0.0005

PHE 115 ILE 116 -0.0003

ILE 116 GLU 117 0.0001

GLU 117 ARG 118 0.0129

ARG 118 TYR 119 0.0004

TYR 119 PRO 120 -0.0002

PRO 120 ARG 121 0.0001

ARG 121 VAL 122 0.0001

VAL 122 SER 123 -0.0003

SER 123 LEU 124 -0.0001

LEU 124 HIS 125 0.0001

HIS 125 MET 126 -0.0001

MET 126 HIS 127 0.0001

HIS 127 GLN 128 0.0001

GLN 128 GLY 129 0.0001

GLY 129 SER 130 -0.0004

SER 130 PRO 131 -0.0009

PRO 131 THR 132 0.0000

THR 132 GLN 133 -0.0004

GLN 133 ILE 134 -0.0003

ILE 134 ALA 135 -0.0001

ALA 135 GLU 136 -0.0001

GLU 136 ALA 137 0.0004

ALA 137 VAL 138 0.0001

VAL 138 SER 139 -0.0001

SER 139 LYS 140 0.0004

LYS 140 GLY 141 0.0002

GLY 141 ASN 142 -0.0001

ASN 142 ALA 143 -0.0001

ALA 143 ASP 144 0.0017

ASP 144 PHE 145 0.0001

PHE 145 ALA 146 -0.0002

ALA 146 ILE 147 -0.0001

ILE 147 ALA 148 -0.0001

ALA 148 THR 149 -0.0004

THR 149 GLU 150 0.0002

GLU 150 ALA 151 -0.0002

ALA 151 LEU 152 -0.0004

LEU 152 HIS 153 0.0000

HIS 153 LEU 154 -0.0001

LEU 154 TYR 155 -0.0003

TYR 155 ASP 156 0.0004

ASP 156 ASP 157 0.0087

ASP 157 LEU 158 -0.0000

LEU 158 VAL 159 -0.0001

VAL 159 MET 160 -0.0001

MET 160 LEU 161 -0.0001

LEU 161 PRO 162 0.0000

PRO 162 CYS 163 -0.0000

CYS 163 TYR 164 0.0001

TYR 164 HIS 165 -0.0000

HIS 165 TRP 166 -0.0001

TRP 166 ASN 167 -0.0000

ASN 167 ARG 168 -0.0000

ARG 168 SER 169 -0.0002

SER 169 ILE 170 0.0113

ILE 170 VAL 171 0.0003

VAL 171 VAL 172 -0.0002

VAL 172 THR 173 -0.0004

THR 173 PRO 174 -0.0002

PRO 174 GLU 175 -0.0002

GLU 175 HIS 176 0.0001

HIS 176 PRO 177 -0.0002

PRO 177 LEU 178 -0.0001

LEU 178 ALA 179 0.0002

ALA 179 THR 180 -0.0002

THR 180 LYS 181 0.0001

LYS 181 GLY 182 0.0000

GLY 182 SER 183 -0.0015

SER 183 VAL 184 -0.0002

VAL 184 SER 185 0.0003

SER 185 ILE 186 0.0003

ILE 186 GLU 187 0.0003

GLU 187 GLU 188 0.0003

GLU 188 LEU 189 0.0003

LEU 189 ALA 190 0.0002

ALA 190 GLN 191 0.0001

GLN 191 GLN 191 -0.0032

GLN 191 TYR 192 -0.0002

TYR 192 PRO 193 0.0001

PRO 193 LEU 194 -0.0000

LEU 194 VAL 195 -0.0001

VAL 195 THR 196 0.0036

THR 196 TYR 197 -0.0004

TYR 197 THR 198 0.0000

THR 198 PHE 199 -0.0004

PHE 199 GLY 200 0.0001

GLY 200 PHE 201 0.0002

PHE 201 THR 202 0.0000

THR 202 GLY 203 -0.0001

GLY 203 ARG 204 -0.0003

ARG 204 SER 205 0.0003

SER 205 GLU 206 0.0000

GLU 206 LEU 207 -0.0002

LEU 207 ASP 208 0.0002

ASP 208 THR 209 0.0000

THR 209 ALA 210 -0.0001

ALA 210 PHE 211 -0.0000

PHE 211 ASN 212 -0.0000

ASN 212 ARG 213 -0.0001

ARG 213 ALA 214 0.0000

ALA 214 GLY 215 -0.0001

GLY 215 LEU 216 -0.0001

LEU 216 THR 217 -0.0000

THR 217 PRO 218 -0.0002

PRO 218 ARG 219 0.0001

ARG 219 ILE 220 -0.0000

ILE 220 VAL 221 -0.0000

VAL 221 PHE 222 0.0109

PHE 222 THR 223 -0.0001

THR 223 ALA 224 -0.0002

ALA 224 THR 225 0.0002

THR 225 ASP 226 -0.0002

ASP 226 ALA 227 0.0003

ALA 227 ASP 228 0.0004

ASP 228 VAL 229 0.0004

VAL 229 ILE 230 0.0001

ILE 230 LYS 231 0.0001

LYS 231 THR 232 -0.0001

THR 232 TYR 233 0.0001

TYR 233 VAL 234 0.0003

VAL 234 ARG 235 0.0012

ARG 235 LEU 236 0.0001

LEU 236 GLY 237 -0.0000

GLY 237 LEU 238 0.0001

LEU 238 GLY 239 -0.0000

GLY 239 VAL 240 -0.0004

VAL 240 GLY 241 0.0003

GLY 241 VAL 242 -0.0003

VAL 242 ILE 243 0.0002

ILE 243 ALA 244 -0.0003

ALA 244 SER 245 0.0003

SER 245 MET 246 0.0000

MET 246 ALA 247 0.0002

ALA 247 VAL 248 0.0021

VAL 248 ASP 249 -0.0001

ASP 249 PRO 250 -0.0001

PRO 250 VAL 251 -0.0001

VAL 251 SER 252 0.0001

SER 252 ASP 253 -0.0003

ASP 253 PRO 254 -0.0002

PRO 254 ASP 255 0.0000

ASP 255 LEU 256 0.0005

LEU 256 VAL 257 -0.0004

VAL 257 LYS 258 0.0001

LYS 258 LEU 259 -0.0001

LEU 259 ASP 260 0.0003

ASP 260 ALA 261 -0.0049

ALA 261 ASN 262 -0.0003

ASN 262 GLY 263 0.0002

GLY 263 ILE 264 -0.0002

ILE 264 PHE 265 0.0000

PHE 265 SER 266 -0.0001

SER 266 HIS 267 0.0002

HIS 267 SER 268 -0.0004

SER 268 THR 269 -0.0002

THR 269 THR 270 0.0002

THR 270 LYS 271 0.0001

LYS 271 ILE 272 0.0003

ILE 272 GLY 273 -0.0004

GLY 273 PHE 274 0.0205

PHE 274 ARG 275 0.0004

ARG 275 ARG 276 0.0004

ARG 276 SER 277 -0.0002

SER 277 THR 278 0.0002

THR 278 PHE 279 0.0000

PHE 279 LEU 280 0.0000

LEU 280 ARG 281 0.0002

ARG 281 SER 282 -0.0001

SER 282 TYR 283 0.0001

TYR 283 MET 284 -0.0002

MET 284 TYR 285 -0.0003

TYR 285 ASP 286 0.0005

ASP 286 PHE 287 0.0087

PHE 287 ILE 288 0.0003

ILE 288 GLN 289 -0.0001

GLN 289 ARG 290 0.0004

ARG 290 PHE 291 -0.0002

PHE 291 ALA 292 -0.0004

ALA 292 PRO 293 -0.0000

PRO 293 HIS 294 -0.0002

HIS 294 LEU 295 0.0005

LEU 295 THR 296 0.0001

THR 296 ARG 297 0.0002

ARG 297 ASP 298 -0.0001

ASP 298 VAL 299 -0.0001

VAL 299 VAL 300 0.0059

VAL 300 ASP 301 0.0002

ASP 301 THR 302 -0.0002

THR 302 ALA 303 0.0001

ALA 303 VAL 304 -0.0003

VAL 304 ALA 305 0.0002

ALA 305 LEU 306 -0.0005

LEU 306 ARG 307 0.0004

ARG 307 SER 308 -0.0001

SER 308 ASN 309 0.0004

ASN 309 GLU 310 -0.0004

GLU 310 ASP 311 -0.0001

ASP 311 ILE 312 -0.0001

ILE 312 GLU 313 -0.0003

GLU 313 ALA 314 0.0001

ALA 314 MET 315 -0.0000

MET 315 PHE 316 -0.0001

PHE 316 LYS 317 -0.0001

LYS 317 ASP 318 0.0002

ASP 318 ILE 319 -0.0000

ILE 319 LYS 320 -0.0002

LYS 320 LEU 321 0.0002

LEU 321 PRO 322 -0.0002

PRO 322 GLU 323 0.0000

GLU 323 LYS 324 0.0004

LYS 324 MET 1 -0.0157

MET 1 LYS 2 0.0001

LYS 2 LEU 3 -0.0000

LEU 3 GLN 4 -0.0001

GLN 4 GLN 5 -0.0001

GLN 5 LEU 6 -0.0002

LEU 6 ARG 7 -0.0002

ARG 7 TYR 8 0.0001

TYR 8 ILE 9 0.0002

ILE 9 VAL 10 0.0001

VAL 10 GLU 11 -0.0003

GLU 11 VAL 12 0.0002

VAL 12 VAL 13 -0.0003

VAL 13 ASN 14 -0.0023

ASN 14 HIS 15 -0.0000

HIS 15 ASN 16 -0.0000

ASN 16 LEU 17 -0.0002

LEU 17 ASN 18 -0.0000

ASN 18 VAL 19 0.0001

VAL 19 SER 20 -0.0000

SER 20 SER 21 -0.0002

SER 21 THR 22 -0.0002

THR 22 ALA 23 0.0001

ALA 23 GLU 24 -0.0003

GLU 24 GLY 25 -0.0001

GLY 25 LEU 26 0.0002

LEU 26 TYR 27 0.0008

TYR 27 THR 28 0.0002

THR 28 SER 29 -0.0003

SER 29 GLN 30 -0.0001

GLN 30 PRO 31 -0.0000

PRO 31 GLY 32 -0.0001

GLY 32 ILE 33 0.0002

ILE 33 SER 34 -0.0001

SER 34 LYS 35 -0.0001

LYS 35 GLN 36 0.0000

GLN 36 VAL 37 0.0002

VAL 37 ARG 38 0.0002

ARG 38 MET 39 0.0002

MET 39 LEU 40 -0.0009

LEU 40 GLU 41 -0.0001

GLU 41 ASP 42 -0.0001

ASP 42 GLU 43 -0.0001

GLU 43 LEU 44 0.0001

LEU 44 GLY 45 -0.0002

GLY 45 ILE 46 -0.0002

ILE 46 GLN 47 0.0001

GLN 47 ILE 48 -0.0003

ILE 48 PHE 49 -0.0001

PHE 49 ALA 50 0.0001

ALA 50 ARG 51 0.0001

ARG 51 SER 52 -0.0003

SER 52 GLY 53 0.0017

GLY 53 LYS 54 0.0003

LYS 54 HIS 55 -0.0000

HIS 55 LEU 56 -0.0002

LEU 56 THR 57 0.0000

THR 57 GLN 58 -0.0002

GLN 58 VAL 59 0.0002

VAL 59 THR 60 0.0000

THR 60 PRO 61 0.0001

PRO 61 ALA 62 0.0001

ALA 62 GLY 63 0.0000

GLY 63 GLN 64 0.0001

GLN 64 GLU 65 0.0002

GLU 65 ILE 66 0.0042

ILE 66 ILE 67 0.0002

ILE 67 ARG 68 0.0002

ARG 68 ILE 69 0.0001

ILE 69 ALA 70 0.0001

ALA 70 ARG 71 0.0003

ARG 71 GLU 72 -0.0003

GLU 72 VAL 73 -0.0000

VAL 73 LEU 74 0.0003

LEU 74 SER 75 -0.0005

SER 75 LYS 76 0.0002

LYS 76 VAL 77 0.0004

VAL 77 ASP 78 -0.0003

ASP 78 ALA 79 0.0085

ALA 79 ILE 80 0.0004

ILE 80 LYS 81 -0.0003

LYS 81 SER 82 0.0001

SER 82 VAL 83 0.0000

VAL 83 ALA 84 -0.0001

ALA 84 GLY 85 -0.0002

GLY 85 GLU 86 0.0000

GLU 86 HIS 87 0.0000

HIS 87 THR 88 0.0000

THR 88 TRP 89 -0.0000

TRP 89 PRO 90 -0.0004

PRO 90 ASP 91 -0.0002

ASP 91 LYS 92 -0.0029

LYS 92 GLY 93 -0.0002

GLY 93 SER 94 -0.0001

SER 94 LEU 95 0.0002

LEU 95 TYR 96 0.0001

TYR 96 VAL 97 0.0001

VAL 97 ALA 98 0.0001

ALA 98 THR 99 -0.0001

THR 99 THR 100 0.0002

THR 100 HIS 101 -0.0004

HIS 101 THR 102 -0.0000

THR 102 GLN 103 0.0002

GLN 103 ALA 104 -0.0001

ALA 104 ARG 105 0.0030

ARG 105 TYR 106 -0.0002

TYR 106 ALA 107 -0.0002

ALA 107 LEU 108 -0.0005

LEU 108 PRO 109 -0.0001

PRO 109 GLY 110 0.0000

GLY 110 VAL 111 0.0002

VAL 111 ILE 112 0.0000

ILE 112 LYS 113 -0.0001

LYS 113 GLY 114 -0.0001

GLY 114 PHE 115 0.0003

PHE 115 ILE 116 0.0000

ILE 116 GLU 117 0.0002

GLU 117 ARG 118 0.0117

ARG 118 TYR 119 0.0001

TYR 119 PRO 120 -0.0001

PRO 120 ARG 121 -0.0003

ARG 121 VAL 122 0.0002

VAL 122 SER 123 -0.0001

SER 123 LEU 124 -0.0000

LEU 124 HIS 125 0.0002

HIS 125 MET 126 0.0001

MET 126 HIS 127 -0.0002

HIS 127 GLN 128 0.0003

GLN 128 GLY 129 -0.0000

GLY 129 SER 130 -0.0002

SER 130 PRO 131 0.0012

PRO 131 THR 132 0.0002

THR 132 GLN 133 -0.0003

GLN 133 ILE 134 0.0000

ILE 134 ALA 135 -0.0003

ALA 135 GLU 136 -0.0002

GLU 136 ALA 137 0.0004

ALA 137 VAL 138 0.0001

VAL 138 SER 139 -0.0003

SER 139 LYS 140 -0.0000

LYS 140 GLY 141 0.0004

GLY 141 ASN 142 -0.0003

ASN 142 ALA 143 0.0000

ALA 143 ASP 144 0.0000

ASP 144 PHE 145 0.0003

PHE 145 ALA 146 -0.0001

ALA 146 ILE 147 0.0000

ILE 147 ALA 148 -0.0004

ALA 148 THR 149 -0.0003

THR 149 GLU 150 0.0002

GLU 150 ALA 151 -0.0002

ALA 151 LEU 152 -0.0002

LEU 152 HIS 153 0.0002

HIS 153 LEU 154 0.0001

LEU 154 TYR 155 -0.0003

TYR 155 ASP 156 0.0002

ASP 156 ASP 157 0.0065

ASP 157 LEU 158 -0.0002

LEU 158 VAL 159 -0.0000

VAL 159 MET 160 -0.0004

MET 160 LEU 161 -0.0002

LEU 161 PRO 162 -0.0000

PRO 162 CYS 163 -0.0002

CYS 163 TYR 164 0.0002

TYR 164 HIS 165 0.0003

HIS 165 TRP 166 0.0001

TRP 166 ASN 167 0.0001

ASN 167 ARG 168 -0.0004

ARG 168 SER 169 0.0001

SER 169 ILE 170 0.0099

ILE 170 VAL 171 -0.0002

VAL 171 VAL 172 0.0002

VAL 172 THR 173 0.0000

THR 173 PRO 174 -0.0000

PRO 174 GLU 175 0.0004

GLU 175 HIS 176 0.0000

HIS 176 PRO 177 0.0002

PRO 177 LEU 178 0.0003

LEU 178 ALA 179 0.0002

ALA 179 THR 180 0.0000

THR 180 LYS 181 -0.0001

LYS 181 GLY 182 -0.0002

GLY 182 SER 183 -0.0007

SER 183 VAL 184 0.0001

VAL 184 SER 185 -0.0001

SER 185 ILE 186 -0.0002

ILE 186 GLU 187 -0.0002

GLU 187 GLU 188 -0.0003

GLU 188 LEU 189 -0.0000

LEU 189 ALA 190 0.0001

ALA 190 GLN 191 0.0000

GLN 191 GLN 191 -0.0006

GLN 191 TYR 192 -0.0001

TYR 192 PRO 193 0.0000

PRO 193 LEU 194 0.0002

LEU 194 VAL 195 -0.0000

VAL 195 THR 196 0.0044

THR 196 TYR 197 -0.0001

TYR 197 THR 198 0.0000

THR 198 PHE 199 -0.0003

PHE 199 GLY 200 -0.0001

GLY 200 PHE 201 0.0001

PHE 201 THR 202 -0.0000

THR 202 GLY 203 -0.0003

GLY 203 ARG 204 -0.0000

ARG 204 SER 205 -0.0003

SER 205 GLU 206 -0.0002

GLU 206 LEU 207 -0.0001

LEU 207 ASP 208 -0.0002

ASP 208 THR 209 -0.0010

THR 209 ALA 210 -0.0000

ALA 210 PHE 211 -0.0002

PHE 211 ASN 212 -0.0002

ASN 212 ARG 213 -0.0002

ARG 213 ALA 214 -0.0001

ALA 214 GLY 215 -0.0003

GLY 215 LEU 216 0.0003

LEU 216 THR 217 0.0000

THR 217 PRO 218 0.0002

PRO 218 ARG 219 -0.0002

ARG 219 ILE 220 -0.0004

ILE 220 VAL 221 0.0003

VAL 221 PHE 222 0.0117

PHE 222 THR 223 0.0001

THR 223 ALA 224 -0.0002

ALA 224 THR 225 0.0001

THR 225 ASP 226 -0.0001

ASP 226 ALA 227 -0.0003

ALA 227 ASP 228 0.0001

ASP 228 VAL 229 0.0001

VAL 229 ILE 230 -0.0000

ILE 230 LYS 231 0.0002

LYS 231 THR 232 0.0004

THR 232 TYR 233 -0.0002

TYR 233 VAL 234 -0.0001

VAL 234 ARG 235 0.0019

ARG 235 LEU 236 -0.0001

LEU 236 GLY 237 0.0003

GLY 237 LEU 238 -0.0002

LEU 238 GLY 239 -0.0002

GLY 239 VAL 240 0.0002

VAL 240 GLY 241 0.0001

GLY 241 VAL 242 -0.0000

VAL 242 ILE 243 -0.0002

ILE 243 ALA 244 0.0000

ALA 244 SER 245 0.0000

SER 245 MET 246 0.0002

MET 246 ALA 247 -0.0000

ALA 247 VAL 248 0.0025

VAL 248 ASP 249 -0.0001

ASP 249 PRO 250 0.0005

PRO 250 VAL 251 -0.0000

VAL 251 SER 252 -0.0000

SER 252 ASP 253 -0.0003

ASP 253 PRO 254 0.0003

PRO 254 ASP 255 -0.0003

ASP 255 LEU 256 0.0002

LEU 256 VAL 257 0.0001

VAL 257 LYS 258 0.0001

LYS 258 LEU 259 0.0002

LEU 259 ASP 260 -0.0001

ASP 260 ALA 261 -0.0040

ALA 261 ASN 262 -0.0001

ASN 262 GLY 263 0.0002

GLY 263 ILE 264 -0.0002

ILE 264 PHE 265 0.0002

PHE 265 SER 266 -0.0004

SER 266 HIS 267 -0.0001

HIS 267 SER 268 -0.0002

SER 268 THR 269 0.0001

THR 269 THR 270 -0.0002

THR 270 LYS 271 0.0003

LYS 271 ILE 272 -0.0001

ILE 272 GLY 273 0.0001

GLY 273 PHE 274 0.0173

PHE 274 ARG 275 -0.0002

ARG 275 ARG 276 0.0003

ARG 276 SER 277 -0.0000

SER 277 THR 278 -0.0001

THR 278 PHE 279 -0.0003

PHE 279 LEU 280 -0.0000

LEU 280 ARG 281 -0.0001

ARG 281 SER 282 -0.0000

SER 282 TYR 283 0.0002

TYR 283 MET 284 0.0001

MET 284 TYR 285 -0.0001

TYR 285 ASP 286 -0.0001

ASP 286 PHE 287 0.0054

PHE 287 ILE 288 -0.0002

ILE 288 GLN 289 -0.0000

GLN 289 ARG 290 0.0002

ARG 290 PHE 291 0.0002

PHE 291 ALA 292 0.0000

ALA 292 PRO 293 0.0003

PRO 293 HIS 294 0.0004

HIS 294 LEU 295 -0.0002

LEU 295 THR 296 0.0002

THR 296 ARG 297 -0.0002

ARG 297 ASP 298 -0.0002

ASP 298 VAL 299 0.0002

VAL 299 VAL 300 0.0051

VAL 300 ASP 301 -0.0003

ASP 301 THR 302 0.0000

THR 302 ALA 303 -0.0003

ALA 303 VAL 304 0.0001

VAL 304 ALA 305 0.0002

ALA 305 LEU 306 0.0001

LEU 306 ARG 307 -0.0002

ARG 307 SER 308 -0.0000

SER 308 ASN 309 0.0001

ASN 309 GLU 310 0.0001

GLU 310 ASP 311 -0.0004

ASP 311 ILE 312 0.0003

ILE 312 GLU 313 0.0010

GLU 313 ALA 314 -0.0004

ALA 314 MET 315 -0.0000

MET 315 PHE 316 -0.0003

PHE 316 LYS 317 0.0002

LYS 317 ASP 318 0.0002

ASP 318 ILE 319 0.0000

ILE 319 LYS 320 -0.0003

LYS 320 LEU 321 0.0001

LEU 321 PRO 322 -0.0000

PRO 322 GLU 323 -0.0002

GLU 323 LYS 324 0.0000

LYS 324 MET 1 0.0018

MET 1 LYS 2 0.0005

LYS 2 LEU 3 -0.0002

LEU 3 GLN 4 0.0001

GLN 4 GLN 5 -0.0000

GLN 5 LEU 6 -0.0001

LEU 6 ARG 7 0.0001

ARG 7 TYR 8 -0.0001

TYR 8 ILE 9 -0.0001

ILE 9 VAL 10 -0.0000

VAL 10 GLU 11 0.0003

GLU 11 VAL 12 0.0001

VAL 12 VAL 13 -0.0002

VAL 13 ASN 14 0.0005

ASN 14 HIS 15 0.0002

HIS 15 ASN 16 0.0002

ASN 16 LEU 17 -0.0003

LEU 17 ASN 18 0.0004

ASN 18 VAL 19 -0.0002

VAL 19 SER 20 0.0000

SER 20 SER 21 0.0003

SER 21 THR 22 0.0003

THR 22 ALA 23 -0.0003

ALA 23 GLU 24 0.0001

GLU 24 GLY 25 -0.0000

GLY 25 LEU 26 -0.0000

LEU 26 TYR 27 0.0030

TYR 27 THR 28 0.0002

THR 28 SER 29 -0.0003

SER 29 GLN 30 -0.0002

GLN 30 PRO 31 -0.0002

PRO 31 GLY 32 -0.0002

GLY 32 ILE 33 -0.0002

ILE 33 SER 34 0.0000

SER 34 LYS 35 -0.0000

LYS 35 GLN 36 0.0001

GLN 36 VAL 37 0.0001

VAL 37 ARG 38 0.0001

ARG 38 MET 39 0.0001

MET 39 LEU 40 -0.0015

LEU 40 GLU 41 -0.0002

GLU 41 ASP 42 -0.0000

ASP 42 GLU 43 -0.0002

GLU 43 LEU 44 0.0000

LEU 44 GLY 45 -0.0000

GLY 45 ILE 46 -0.0000

ILE 46 GLN 47 -0.0002

GLN 47 ILE 48 -0.0003

ILE 48 PHE 49 -0.0003

PHE 49 ALA 50 -0.0001

ALA 50 ARG 51 0.0001

ARG 51 SER 52 0.0000

SER 52 GLY 53 -0.0004

GLY 53 LYS 54 0.0001

LYS 54 HIS 55 0.0005

HIS 55 LEU 56 -0.0004

LEU 56 THR 57 0.0002

THR 57 GLN 58 0.0001

GLN 58 VAL 59 0.0002

VAL 59 THR 60 0.0000

THR 60 PRO 61 0.0001

PRO 61 ALA 62 -0.0000

ALA 62 GLY 63 -0.0003

GLY 63 GLN 64 0.0001

GLN 64 GLU 65 0.0001

GLU 65 ILE 66 0.0036

ILE 66 ILE 67 -0.0001

ILE 67 ARG 68 -0.0004

ARG 68 ILE 69 0.0001

ILE 69 ALA 70 -0.0001

ALA 70 ARG 71 -0.0002

ARG 71 GLU 72 0.0002

GLU 72 VAL 73 0.0001

VAL 73 LEU 74 0.0003

LEU 74 SER 75 -0.0003

SER 75 LYS 76 0.0002

LYS 76 VAL 77 0.0002

VAL 77 ASP 78 -0.0002

ASP 78 ALA 79 0.0239

ALA 79 ILE 80 0.0001

ILE 80 LYS 81 0.0001

LYS 81 SER 82 0.0004

SER 82 VAL 83 0.0001

VAL 83 ALA 84 -0.0000

ALA 84 GLY 85 0.0002

GLY 85 GLU 86 -0.0001

GLU 86 HIS 87 -0.0000

HIS 87 THR 88 0.0003

THR 88 TRP 89 -0.0001

TRP 89 PRO 90 0.0003

PRO 90 ASP 91 0.0002

ASP 91 LYS 92 0.0147

LYS 92 GLY 93 0.0002

GLY 93 SER 94 -0.0001

SER 94 LEU 95 -0.0001

LEU 95 TYR 96 0.0001

TYR 96 VAL 97 -0.0002

VAL 97 ALA 98 0.0001

ALA 98 THR 99 -0.0000

THR 99 THR 100 0.0002

THR 100 HIS 101 -0.0002

HIS 101 THR 102 -0.0000

THR 102 GLN 103 -0.0000

GLN 103 ALA 104 0.0002

ALA 104 ARG 105 -0.0006

ARG 105 TYR 106 0.0003

TYR 106 ALA 107 0.0001

ALA 107 LEU 108 -0.0000

LEU 108 PRO 109 0.0002

PRO 109 GLY 110 -0.0000

GLY 110 VAL 111 0.0001

VAL 111 ILE 112 -0.0002

ILE 112 LYS 113 -0.0002

LYS 113 GLY 114 0.0003

GLY 114 PHE 115 0.0000

PHE 115 ILE 116 0.0002

ILE 116 GLU 117 0.0000

GLU 117 ARG 118 0.0002

ARG 118 TYR 119 0.0002

TYR 119 PRO 120 0.0003

PRO 120 ARG 121 0.0000

ARG 121 VAL 122 0.0001

VAL 122 SER 123 -0.0001

SER 123 LEU 124 0.0000

LEU 124 HIS 125 -0.0002

HIS 125 MET 126 -0.0003

MET 126 HIS 127 -0.0003

HIS 127 GLN 128 0.0002

GLN 128 GLY 129 0.0002

GLY 129 SER 130 -0.0005

SER 130 PRO 131 0.0000

PRO 131 THR 132 -0.0002

THR 132 GLN 133 0.0004

GLN 133 ILE 134 -0.0001

ILE 134 ALA 135 -0.0003

ALA 135 GLU 136 0.0000

GLU 136 ALA 137 0.0002

ALA 137 VAL 138 -0.0002

VAL 138 SER 139 0.0006

SER 139 LYS 140 -0.0002

LYS 140 GLY 141 -0.0004

GLY 141 ASN 142 -0.0002

ASN 142 ALA 143 -0.0004

ALA 143 ASP 144 -0.0007

ASP 144 PHE 145 0.0003

PHE 145 ALA 146 -0.0002

ALA 146 ILE 147 0.0001

ILE 147 ALA 148 -0.0001

ALA 148 THR 149 -0.0001

THR 149 GLU 150 0.0001

GLU 150 ALA 151 0.0001

ALA 151 LEU 152 -0.0004

LEU 152 HIS 153 -0.0002

HIS 153 LEU 154 -0.0000

LEU 154 TYR 155 0.0000

TYR 155 ASP 156 0.0001

ASP 156 ASP 157 -0.0025

ASP 157 LEU 158 -0.0000

LEU 158 VAL 159 -0.0000

VAL 159 MET 160 0.0004

MET 160 LEU 161 0.0001

LEU 161 PRO 162 -0.0003

PRO 162 CYS 163 0.0002

CYS 163 TYR 164 0.0001

TYR 164 HIS 165 -0.0001

HIS 165 TRP 166 -0.0001

TRP 166 ASN 167 -0.0002

ASN 167 ARG 168 0.0001

ARG 168 SER 169 -0.0001

SER 169 ILE 170 0.0007

ILE 170 VAL 171 0.0002

VAL 171 VAL 172 -0.0001

VAL 172 THR 173 -0.0001

THR 173 PRO 174 0.0002

PRO 174 GLU 175 -0.0003

GLU 175 HIS 176 0.0001

HIS 176 PRO 177 0.0002

PRO 177 LEU 178 0.0002

LEU 178 ALA 179 -0.0002

ALA 179 THR 180 -0.0004

THR 180 LYS 181 -0.0000

LYS 181 GLY 182 0.0001

GLY 182 SER 183 0.0017

SER 183 VAL 184 0.0004

VAL 184 SER 185 -0.0001

SER 185 ILE 186 -0.0003

ILE 186 GLU 187 0.0000

GLU 187 GLU 188 0.0002

GLU 188 LEU 189 -0.0003

LEU 189 ALA 190 0.0003

ALA 190 GLN 191 -0.0001

GLN 191 TYR 192 0.0001

TYR 192 PRO 193 -0.0001

PRO 193 LEU 194 -0.0001

LEU 194 VAL 195 0.0002

VAL 195 THR 196 -0.0003

THR 196 TYR 197 -0.0002

TYR 197 THR 198 -0.0001

THR 198 PHE 199 0.0004

PHE 199 GLY 200 0.0001

GLY 200 PHE 201 0.0000

PHE 201 THR 202 -0.0003

THR 202 GLY 203 -0.0000

GLY 203 ARG 204 -0.0000

ARG 204 SER 205 -0.0002

SER 205 GLU 206 0.0000

GLU 206 LEU 207 0.0001

LEU 207 ASP 208 -0.0003

ASP 208 THR 209 0.0008

THR 209 ALA 210 0.0000

ALA 210 PHE 211 -0.0003

PHE 211 ASN 212 -0.0001

ASN 212 ARG 213 0.0003

ARG 213 ALA 214 0.0002

ALA 214 GLY 215 -0.0003

GLY 215 LEU 216 -0.0002

LEU 216 THR 217 0.0002

THR 217 PRO 218 0.0002

PRO 218 ARG 219 -0.0004

ARG 219 ILE 220 -0.0002

ILE 220 VAL 221 -0.0001

VAL 221 PHE 222 0.0005

PHE 222 THR 223 0.0002

THR 223 ALA 224 -0.0001

ALA 224 THR 225 -0.0005

THR 225 ASP 226 -0.0003

ASP 226 ALA 227 0.0001

ALA 227 ASP 228 0.0000

ASP 228 VAL 229 -0.0002

VAL 229 ILE 230 0.0001

ILE 230 LYS 231 -0.0005

LYS 231 THR 232 -0.0001

THR 232 TYR 233 0.0001

TYR 233 VAL 234 -0.0001

VAL 234 ARG 235 0.0029

ARG 235 LEU 236 -0.0001

LEU 236 GLY 237 -0.0003

GLY 237 LEU 238 0.0003

LEU 238 GLY 239 -0.0003

GLY 239 VAL 240 -0.0002

VAL 240 GLY 241 0.0003

GLY 241 VAL 242 -0.0003

VAL 242 ILE 243 0.0000

ILE 243 ALA 244 -0.0002

ALA 244 SER 245 -0.0002

SER 245 MET 246 -0.0003

MET 246 ALA 247 -0.0001

ALA 247 VAL 248 -0.0000

VAL 248 ASP 249 0.0000

ASP 249 PRO 250 -0.0003

PRO 250 VAL 251 -0.0001

VAL 251 SER 252 -0.0001

SER 252 ASP 253 -0.0000

ASP 253 PRO 254 -0.0002

PRO 254 ASP 255 -0.0001

ASP 255 LEU 256 0.0001

LEU 256 VAL 257 0.0001

VAL 257 LYS 258 0.0003

LYS 258 LEU 259 -0.0002

LEU 259 ASP 260 0.0003

ASP 260 ALA 261 0.0020

ALA 261 ASN 262 -0.0004

ASN 262 GLY 263 0.0003

GLY 263 ILE 264 0.0002

ILE 264 PHE 265 -0.0001

PHE 265 SER 266 0.0000

SER 266 HIS 267 -0.0004

HIS 267 SER 268 0.0004

SER 268 THR 269 -0.0001

THR 269 THR 270 0.0002

THR 270 LYS 271 -0.0001

LYS 271 ILE 272 -0.0000

ILE 272 GLY 273 0.0004

GLY 273 PHE 274 -0.0006

PHE 274 ARG 275 -0.0001

ARG 275 ARG 276 0.0001

ARG 276 SER 277 -0.0001

SER 277 THR 278 0.0001

THR 278 PHE 279 0.0000

PHE 279 LEU 280 0.0001

LEU 280 ARG 281 -0.0002

ARG 281 SER 282 -0.0000

SER 282 TYR 283 -0.0000

TYR 283 MET 284 -0.0002

MET 284 TYR 285 0.0001

TYR 285 ASP 286 0.0006

ASP 286 PHE 287 -0.0001

PHE 287 ILE 288 -0.0001

ILE 288 GLN 289 0.0001

GLN 289 ARG 290 -0.0003

ARG 290 PHE 291 0.0001

PHE 291 ALA 292 0.0001

ALA 292 PRO 293 0.0004

PRO 293 HIS 294 -0.0002

HIS 294 LEU 295 0.0003

LEU 295 THR 296 0.0000

THR 296 ARG 297 0.0000

ARG 297 ASP 298 0.0002

ASP 298 VAL 299 -0.0001

VAL 299 VAL 300 0.0004

VAL 300 ASP 301 -0.0002

ASP 301 THR 302 -0.0002

THR 302 ALA 303 -0.0003

ALA 303 VAL 304 -0.0000

VAL 304 ALA 305 0.0002

ALA 305 LEU 306 -0.0001

LEU 306 ARG 307 -0.0002

ARG 307 SER 308 -0.0002

SER 308 ASN 309 0.0002

ASN 309 GLU 310 -0.0003

GLU 310 ASP 311 -0.0002

ASP 311 ILE 312 0.0001

ILE 312 GLU 313 -0.0003

GLU 313 ALA 314 -0.0001

ALA 314 MET 315 0.0000

MET 315 PHE 316 -0.0005

PHE 316 LYS 317 -0.0004

LYS 317 ASP 318 0.0004

ASP 318 ILE 319 -0.0002

ILE 319 LYS 320 -0.0001

LYS 320 LEU 321 0.0004

LEU 321 PRO 322 -0.0000

PRO 322 GLU 323 -0.0004

GLU 323 LYS 324 0.0003

LYS 324 MET 1 0.0026

MET 1 LYS 2 -0.0001

LYS 2 LEU 3 -0.0002

LEU 3 GLN 4 0.0005

GLN 4 GLN 5 -0.0001

GLN 5 LEU 6 -0.0000

LEU 6 ARG 7 0.0003

ARG 7 TYR 8 -0.0000

TYR 8 ILE 9 -0.0001

ILE 9 VAL 10 0.0000

VAL 10 GLU 11 -0.0001

GLU 11 VAL 12 -0.0000

VAL 12 VAL 13 0.0002

VAL 13 ASN 14 0.0201

ASN 14 HIS 15 -0.0000

HIS 15 ASN 16 0.0005

ASN 16 LEU 17 -0.0001

LEU 17 ASN 18 -0.0004

ASN 18 VAL 19 0.0004

VAL 19 SER 20 0.0000

SER 20 SER 21 0.0004

SER 21 THR 22 -0.0000

THR 22 ALA 23 0.0004

ALA 23 GLU 24 -0.0004

GLU 24 GLY 25 0.0001

GLY 25 LEU 26 0.0001

LEU 26 TYR 27 0.0033

TYR 27 THR 28 -0.0002

THR 28 SER 29 0.0001

SER 29 GLN 30 -0.0001

GLN 30 PRO 31 -0.0001

PRO 31 GLY 32 -0.0002

GLY 32 ILE 33 -0.0000

ILE 33 SER 34 0.0000

SER 34 LYS 35 0.0002

LYS 35 GLN 36 -0.0002

GLN 36 VAL 37 -0.0001

VAL 37 ARG 38 0.0001

ARG 38 MET 39 -0.0002

MET 39 LEU 40 0.0009

LEU 40 GLU 41 -0.0000

GLU 41 ASP 42 -0.0001

ASP 42 GLU 43 -0.0001

GLU 43 LEU 44 -0.0001

LEU 44 GLY 45 -0.0002

GLY 45 ILE 46 -0.0003

ILE 46 GLN 47 0.0003

GLN 47 ILE 48 -0.0000

ILE 48 PHE 49 -0.0003

PHE 49 ALA 50 0.0003

ALA 50 ARG 51 -0.0002

ARG 51 SER 52 -0.0000

SER 52 GLY 53 -0.0079

GLY 53 LYS 54 -0.0002

LYS 54 HIS 55 0.0000

HIS 55 LEU 56 -0.0001

LEU 56 THR 57 0.0001

THR 57 GLN 58 0.0001

GLN 58 VAL 59 -0.0002

VAL 59 THR 60 -0.0001

THR 60 PRO 61 -0.0000

PRO 61 ALA 62 -0.0000

ALA 62 GLY 63 0.0000

GLY 63 GLN 64 -0.0001

GLN 64 GLU 65 0.0002

GLU 65 ILE 66 -0.0062

ILE 66 ILE 67 0.0001

ILE 67 ARG 68 0.0000

ARG 68 ILE 69 -0.0001

ILE 69 ALA 70 0.0000

ALA 70 ARG 71 0.0003

ARG 71 GLU 72 -0.0002

GLU 72 VAL 73 -0.0001

VAL 73 LEU 74 -0.0003

LEU 74 SER 75 -0.0000

SER 75 LYS 76 -0.0002

LYS 76 VAL 77 -0.0001

VAL 77 ASP 78 0.0001

ASP 78 ALA 79 -0.0107

ALA 79 ILE 80 -0.0003

ILE 80 LYS 81 0.0002

LYS 81 SER 82 0.0002

SER 82 VAL 83 0.0001

VAL 83 ALA 84 -0.0005

ALA 84 GLY 85 0.0003

GLY 85 GLU 86 0.0002

GLU 86 HIS 87 -0.0000

HIS 87 THR 88 -0.0000

THR 88 TRP 89 -0.0002

TRP 89 PRO 90 0.0001

PRO 90 ASP 91 -0.0000

ASP 91 LYS 92 0.0221

LYS 92 GLY 93 0.0004

GLY 93 SER 94 0.0000

SER 94 LEU 95 -0.0003

LEU 95 TYR 96 0.0001

TYR 96 VAL 97 0.0003

VAL 97 ALA 98 -0.0001

ALA 98 THR 99 0.0000

THR 99 THR 100 0.0001

THR 100 HIS 101 -0.0001

HIS 101 THR 102 -0.0002

THR 102 GLN 103 0.0001

GLN 103 ALA 104 0.0003

ALA 104 ARG 105 -0.0014

ARG 105 TYR 106 0.0002

TYR 106 ALA 107 -0.0000

ALA 107 LEU 108 -0.0002

LEU 108 PRO 109 0.0002

PRO 109 GLY 110 -0.0000

GLY 110 VAL 111 0.0000

VAL 111 ILE 112 0.0002

ILE 112 LYS 113 0.0003

LYS 113 GLY 114 0.0002

GLY 114 PHE 115 -0.0003

PHE 115 ILE 116 0.0001

ILE 116 GLU 117 -0.0001

GLU 117 ARG 118 -0.0015

ARG 118 TYR 119 -0.0002

TYR 119 PRO 120 -0.0000

PRO 120 ARG 121 0.0000

ARG 121 VAL 122 0.0000

VAL 122 SER 123 0.0000

SER 123 LEU 124 0.0002

LEU 124 HIS 125 -0.0003

HIS 125 MET 126 -0.0002

MET 126 HIS 127 0.0002

HIS 127 GLN 128 -0.0001

GLN 128 GLY 129 -0.0002

GLY 129 SER 130 -0.0000

SER 130 PRO 131 -0.0024

PRO 131 THR 132 0.0002

THR 132 GLN 133 0.0004

GLN 133 ILE 134 -0.0000

ILE 134 ALA 135 -0.0005

ALA 135 GLU 136 -0.0001

GLU 136 ALA 137 -0.0005

ALA 137 VAL 138 0.0004

VAL 138 SER 139 0.0003

SER 139 LYS 140 0.0001

LYS 140 GLY 141 -0.0001

GLY 141 ASN 142 0.0001

ASN 142 ALA 143 0.0004

ALA 143 ASP 144 -0.0035

ASP 144 PHE 145 -0.0002

PHE 145 ALA 146 -0.0002

ALA 146 ILE 147 0.0003

ILE 147 ALA 148 -0.0000

ALA 148 THR 149 -0.0001

THR 149 GLU 150 -0.0002

GLU 150 ALA 151 0.0002

ALA 151 LEU 152 -0.0001

LEU 152 HIS 153 -0.0004

HIS 153 LEU 154 -0.0001

LEU 154 TYR 155 -0.0003

TYR 155 ASP 156 0.0001

ASP 156 ASP 157 -0.0004

ASP 157 LEU 158 0.0000

LEU 158 VAL 159 0.0004

VAL 159 MET 160 -0.0001

MET 160 LEU 161 0.0003

LEU 161 PRO 162 -0.0000

PRO 162 CYS 163 -0.0001

CYS 163 TYR 164 -0.0000

TYR 164 HIS 165 0.0000

HIS 165 TRP 166 0.0003

TRP 166 ASN 167 0.0001

ASN 167 ARG 168 0.0002

ARG 168 SER 169 -0.0000

SER 169 ILE 170 0.0009

ILE 170 VAL 171 -0.0001

VAL 171 VAL 172 -0.0000

VAL 172 THR 173 -0.0003

THR 173 PRO 174 -0.0001

PRO 174 GLU 175 0.0003

GLU 175 HIS 176 -0.0001

HIS 176 PRO 177 0.0001

PRO 177 LEU 178 0.0000

LEU 178 ALA 179 -0.0002

ALA 179 THR 180 0.0004

THR 180 LYS 181 -0.0004

LYS 181 GLY 182 0.0002

GLY 182 SER 183 0.0015

SER 183 VAL 184 -0.0001

VAL 184 SER 185 -0.0002

SER 185 ILE 186 -0.0000

ILE 186 GLU 187 0.0002

GLU 187 GLU 188 -0.0005

GLU 188 LEU 189 0.0000

LEU 189 ALA 190 0.0003

ALA 190 GLN 191 0.0002

GLN 191 TYR 192 -0.0002

TYR 192 PRO 193 -0.0003

PRO 193 LEU 194 -0.0002

LEU 194 VAL 195 0.0000

VAL 195 THR 196 -0.0001

THR 196 TYR 197 0.0003

TYR 197 THR 198 -0.0004

THR 198 PHE 199 0.0001

PHE 199 GLY 200 -0.0001

GLY 200 PHE 201 0.0001

PHE 201 THR 202 0.0001

THR 202 GLY 203 -0.0006

GLY 203 ARG 204 0.0000

ARG 204 SER 205 0.0001

SER 205 GLU 206 -0.0002

GLU 206 LEU 207 -0.0001

LEU 207 ASP 208 -0.0001

ASP 208 THR 209 -0.0036

THR 209 ALA 210 -0.0001

ALA 210 PHE 211 0.0003

PHE 211 ASN 212 -0.0001

ASN 212 ARG 213 -0.0001

ARG 213 ALA 214 -0.0001

ALA 214 GLY 215 0.0000

GLY 215 LEU 216 -0.0001

LEU 216 THR 217 0.0001

THR 217 PRO 218 -0.0001

PRO 218 ARG 219 0.0002

ARG 219 ILE 220 -0.0002

ILE 220 VAL 221 0.0000

VAL 221 PHE 222 0.0001

PHE 222 THR 223 0.0001

THR 223 ALA 224 0.0002

ALA 224 THR 225 0.0000

THR 225 ASP 226 0.0001

ASP 226 ALA 227 -0.0005

ALA 227 ASP 228 -0.0001

ASP 228 VAL 229 0.0001

VAL 229 ILE 230 -0.0001

ILE 230 LYS 231 0.0000

LYS 231 THR 232 0.0003

THR 232 TYR 233 0.0004

TYR 233 VAL 234 0.0002

VAL 234 ARG 235 -0.0004

ARG 235 LEU 236 0.0001

LEU 236 GLY 237 -0.0001

GLY 237 LEU 238 -0.0001

LEU 238 GLY 239 0.0002

GLY 239 VAL 240 -0.0001

VAL 240 GLY 241 -0.0002

GLY 241 VAL 242 0.0002

VAL 242 ILE 243 -0.0004

ILE 243 ALA 244 -0.0001

ALA 244 SER 245 -0.0002

SER 245 MET 246 -0.0001

MET 246 ALA 247 0.0000

ALA 247 VAL 248 -0.0009

VAL 248 ASP 249 0.0001

ASP 249 PRO 250 -0.0001

PRO 250 VAL 251 -0.0001

VAL 251 SER 252 -0.0000

SER 252 ASP 253 0.0002

ASP 253 PRO 254 0.0003

PRO 254 ASP 255 -0.0001

ASP 255 LEU 256 0.0001

LEU 256 VAL 257 0.0003

VAL 257 LYS 258 0.0001

LYS 258 LEU 259 -0.0004

LEU 259 ASP 260 0.0004

ASP 260 ALA 261 0.0013

ALA 261 ASN 262 0.0001

ASN 262 GLY 263 0.0002

GLY 263 ILE 264 0.0000

ILE 264 PHE 265 0.0004

PHE 265 SER 266 -0.0001

SER 266 HIS 267 0.0002

HIS 267 SER 268 -0.0001

SER 268 THR 269 0.0002

THR 269 THR 270 -0.0001

THR 270 LYS 271 -0.0004

LYS 271 ILE 272 -0.0000

ILE 272 GLY 273 0.0001

GLY 273 PHE 274 -0.0007

PHE 274 ARG 275 -0.0004

ARG 275 ARG 276 0.0000

ARG 276 SER 277 -0.0003

SER 277 THR 278 0.0000

THR 278 PHE 279 -0.0001

PHE 279 LEU 280 -0.0001

LEU 280 ARG 281 -0.0001

ARG 281 SER 282 -0.0003

SER 282 TYR 283 -0.0002

TYR 283 MET 284 -0.0001

MET 284 TYR 285 -0.0005

TYR 285 ASP 286 -0.0002

ASP 286 PHE 287 0.0002

PHE 287 ILE 288 -0.0002

ILE 288 GLN 289 0.0000

GLN 289 ARG 290 0.0002

ARG 290 PHE 291 0.0000

PHE 291 ALA 292 0.0000

ALA 292 PRO 293 0.0000

PRO 293 HIS 294 -0.0003

HIS 294 LEU 295 -0.0000

LEU 295 THR 296 -0.0001

THR 296 ARG 297 0.0003

ARG 297 ASP 298 -0.0004

ASP 298 VAL 299 0.0000

VAL 299 VAL 300 0.0019

VAL 300 ASP 301 -0.0003

ASP 301 THR 302 -0.0003

THR 302 ALA 303 -0.0001

ALA 303 VAL 304 0.0001

VAL 304 ALA 305 0.0004

ALA 305 LEU 306 -0.0002

LEU 306 ARG 307 0.0001

ARG 307 SER 308 0.0000

SER 308 ASN 309 -0.0001

ASN 309 GLU 310 -0.0002

GLU 310 ASP 311 -0.0004

ASP 311 ILE 312 0.0001

ILE 312 GLU 313 -0.0003

GLU 313 ALA 314 -0.0002

ALA 314 MET 315 -0.0001

MET 315 PHE 316 -0.0002

PHE 316 LYS 317 0.0005

LYS 317 ASP 318 0.0000

ASP 318 ILE 319 0.0000

ILE 319 LYS 320 -0.0002

LYS 320 LEU 321 -0.0000

LEU 321 PRO 322 -0.0001

PRO 322 GLU 323 -0.0001

GLU 323 LYS 324 0.0002

LYS 324 MET 1 -0.0012

MET 1 LYS 2 0.0002

LYS 2 LEU 3 0.0002

LEU 3 GLN 4 -0.0000

GLN 4 GLN 5 0.0003

GLN 5 LEU 6 0.0005

LEU 6 ARG 7 0.0002

ARG 7 TYR 8 0.0004

TYR 8 ILE 9 -0.0004

ILE 9 VAL 10 -0.0005

VAL 10 GLU 11 0.0002

GLU 11 VAL 12 -0.0002

VAL 12 VAL 13 -0.0001

VAL 13 ASN 14 0.0030

ASN 14 HIS 15 0.0001

HIS 15 ASN 16 0.0003

ASN 16 LEU 17 -0.0001

LEU 17 ASN 18 -0.0003

ASN 18 VAL 19 0.0002

VAL 19 SER 20 -0.0002

SER 20 SER 21 -0.0003

SER 21 THR 22 0.0003

THR 22 ALA 23 -0.0001

ALA 23 GLU 24 -0.0004

GLU 24 GLY 25 -0.0000

GLY 25 LEU 26 -0.0001

LEU 26 TYR 27 0.0046

TYR 27 THR 28 -0.0003

THR 28 SER 29 0.0003

SER 29 GLN 30 0.0001

GLN 30 PRO 31 0.0001

PRO 31 GLY 32 -0.0001

GLY 32 ILE 33 0.0000

ILE 33 SER 34 0.0002

SER 34 LYS 35 0.0005

LYS 35 GLN 36 0.0000

GLN 36 VAL 37 0.0002

VAL 37 ARG 38 0.0002

ARG 38 MET 39 -0.0001

MET 39 LEU 40 0.0005

LEU 40 GLU 41 0.0001

GLU 41 ASP 42 0.0002

ASP 42 GLU 43 0.0001

GLU 43 LEU 44 -0.0003

LEU 44 GLY 45 0.0001

GLY 45 ILE 46 0.0002

ILE 46 GLN 47 0.0002

GLN 47 ILE 48 -0.0005

ILE 48 PHE 49 -0.0002

PHE 49 ALA 50 -0.0003

ALA 50 ARG 51 -0.0001

ARG 51 SER 52 -0.0001

SER 52 GLY 53 0.0032

GLY 53 LYS 54 -0.0003

LYS 54 HIS 55 -0.0005

HIS 55 LEU 56 -0.0000

LEU 56 THR 57 0.0002

THR 57 GLN 58 0.0002

GLN 58 VAL 59 -0.0002

VAL 59 THR 60 -0.0003

THR 60 PRO 61 -0.0002

PRO 61 ALA 62 0.0004

ALA 62 GLY 63 0.0003

GLY 63 GLN 64 -0.0000

GLN 64 GLU 65 0.0002

GLU 65 ILE 66 0.0100

ILE 66 ILE 67 0.0000

ILE 67 ARG 68 -0.0000

ARG 68 ILE 69 0.0000

ILE 69 ALA 70 -0.0001

ALA 70 ARG 71 -0.0002

ARG 71 GLU 72 0.0002

GLU 72 VAL 73 0.0004

VAL 73 LEU 74 -0.0004

LEU 74 SER 75 0.0001

SER 75 LYS 76 0.0003

LYS 76 VAL 77 -0.0001

VAL 77 ASP 78 -0.0001

ASP 78 ALA 79 0.0107

ALA 79 ILE 80 -0.0002

ILE 80 LYS 81 0.0002

LYS 81 SER 82 0.0000

SER 82 VAL 83 -0.0001

VAL 83 ALA 84 -0.0001

ALA 84 GLY 85 -0.0000

GLY 85 GLU 86 0.0002

GLU 86 HIS 87 -0.0004

HIS 87 THR 88 -0.0002

THR 88 TRP 89 -0.0001

TRP 89 PRO 90 -0.0001

PRO 90 ASP 91 0.0001

ASP 91 LYS 92 0.0032

LYS 92 GLY 93 0.0002

GLY 93 SER 94 0.0001

SER 94 LEU 95 -0.0001

LEU 95 TYR 96 -0.0001

TYR 96 VAL 97 0.0004

VAL 97 ALA 98 0.0002

ALA 98 THR 99 -0.0004

THR 99 THR 100 0.0003

THR 100 HIS 101 0.0001

HIS 101 THR 102 -0.0001

THR 102 GLN 103 0.0003

GLN 103 ALA 104 0.0001

ALA 104 ARG 105 -0.0065

ARG 105 TYR 106 -0.0002

TYR 106 ALA 107 0.0001

ALA 107 LEU 108 -0.0001

LEU 108 PRO 109 -0.0003

PRO 109 GLY 110 -0.0002

GLY 110 VAL 111 0.0002

VAL 111 ILE 112 -0.0002

ILE 112 LYS 113 -0.0003

LYS 113 GLY 114 0.0000

GLY 114 PHE 115 0.0004

PHE 115 ILE 116 -0.0001

ILE 116 GLU 117 0.0001

GLU 117 ARG 118 -0.0071

ARG 118 TYR 119 -0.0000

TYR 119 PRO 120 0.0003

PRO 120 ARG 121 0.0002

ARG 121 VAL 122 0.0002

VAL 122 SER 123 0.0002

SER 123 LEU 124 -0.0004

LEU 124 HIS 125 0.0000

HIS 125 MET 126 -0.0000

MET 126 HIS 127 -0.0001

HIS 127 GLN 128 -0.0004

GLN 128 GLY 129 0.0000

GLY 129 SER 130 -0.0001

SER 130 PRO 131 -0.0016

PRO 131 THR 132 0.0001

THR 132 GLN 133 0.0004

GLN 133 ILE 134 0.0001

ILE 134 ALA 135 0.0000

ALA 135 GLU 136 0.0004

GLU 136 ALA 137 -0.0004

ALA 137 VAL 138 0.0000

VAL 138 SER 139 0.0002

SER 139 LYS 140 -0.0003

LYS 140 GLY 141 0.0002

GLY 141 ASN 142 -0.0001

ASN 142 ALA 143 -0.0001

ALA 143 ASP 144 0.0085

ASP 144 PHE 145 0.0003

PHE 145 ALA 146 -0.0003

ALA 146 ILE 147 0.0003

ILE 147 ALA 148 0.0003

ALA 148 THR 149 0.0001

THR 149 GLU 150 -0.0002

GLU 150 ALA 151 -0.0001

ALA 151 LEU 152 0.0002

LEU 152 HIS 153 -0.0000

HIS 153 LEU 154 -0.0000

LEU 154 TYR 155 0.0002

TYR 155 ASP 156 -0.0001

ASP 156 ASP 157 0.0045

ASP 157 LEU 158 -0.0001

LEU 158 VAL 159 0.0000

VAL 159 MET 160 -0.0001

MET 160 LEU 161 0.0002

LEU 161 PRO 162 0.0001

PRO 162 CYS 163 -0.0002

CYS 163 TYR 164 0.0001

TYR 164 HIS 165 -0.0002

HIS 165 TRP 166 0.0001

TRP 166 ASN 167 -0.0000

ASN 167 ARG 168 -0.0000

ARG 168 SER 169 0.0001

SER 169 ILE 170 -0.0077

ILE 170 VAL 171 0.0003

VAL 171 VAL 172 0.0000

VAL 172 THR 173 0.0001

THR 173 PRO 174 0.0004

PRO 174 GLU 175 0.0002

GLU 175 HIS 176 -0.0002

HIS 176 PRO 177 0.0003

PRO 177 LEU 178 -0.0003

LEU 178 ALA 179 0.0000

ALA 179 THR 180 0.0005

THR 180 LYS 181 0.0002

LYS 181 GLY 182 0.0002

GLY 182 SER 183 0.0031

SER 183 VAL 184 0.0002

VAL 184 SER 185 0.0001

SER 185 ILE 186 -0.0000

ILE 186 GLU 187 0.0001

GLU 187 GLU 188 0.0001

GLU 188 LEU 189 0.0001

LEU 189 ALA 190 0.0001

ALA 190 GLN 191 -0.0001

GLN 191 GLN 191 0.0032

GLN 191 TYR 192 0.0002

TYR 192 PRO 193 -0.0001

PRO 193 LEU 194 0.0001

LEU 194 VAL 195 -0.0001

VAL 195 THR 196 -0.0012

THR 196 TYR 197 -0.0000

TYR 197 THR 198 0.0002

THR 198 PHE 199 -0.0001

PHE 199 GLY 200 -0.0001

GLY 200 PHE 201 -0.0001

PHE 201 THR 202 -0.0001

THR 202 GLY 203 -0.0001

GLY 203 ARG 204 -0.0001

ARG 204 SER 205 0.0002

SER 205 GLU 206 -0.0003

GLU 206 LEU 207 -0.0003

LEU 207 ASP 208 0.0001

ASP 208 THR 209 0.0008

THR 209 ALA 210 -0.0004

ALA 210 PHE 211 0.0001

PHE 211 ASN 212 0.0004

ASN 212 ARG 213 -0.0001

ARG 213 ALA 214 0.0001

ALA 214 GLY 215 -0.0003

GLY 215 LEU 216 0.0002

LEU 216 THR 217 -0.0002

THR 217 PRO 218 -0.0002

PRO 218 ARG 219 0.0005

ARG 219 ILE 220 -0.0003

ILE 220 VAL 221 -0.0002

VAL 221 PHE 222 0.0069

PHE 222 THR 223 -0.0000

THR 223 ALA 224 -0.0001

ALA 224 THR 225 0.0000

THR 225 ASP 226 -0.0001

ASP 226 ALA 227 -0.0002

ALA 227 ASP 228 -0.0000

ASP 228 VAL 229 -0.0002

VAL 229 ILE 230 0.0002

ILE 230 LYS 231 -0.0001

LYS 231 THR 232 -0.0001

THR 232 TYR 233 -0.0002

TYR 233 VAL 234 -0.0000

VAL 234 ARG 235 0.0022

ARG 235 LEU 236 0.0000

LEU 236 GLY 237 0.0003

GLY 237 LEU 238 0.0002

LEU 238 GLY 239 -0.0003

GLY 239 VAL 240 0.0001

VAL 240 GLY 241 -0.0003

GLY 241 VAL 242 -0.0000

VAL 242 ILE 243 -0.0001

ILE 243 ALA 244 -0.0002

ALA 244 SER 245 0.0001

SER 245 MET 246 0.0004

MET 246 ALA 247 0.0002

ALA 247 VAL 248 -0.0056

VAL 248 ASP 249 0.0001

ASP 249 PRO 250 0.0001

PRO 250 VAL 251 -0.0002

VAL 251 SER 252 0.0004

SER 252 ASP 253 -0.0001

ASP 253 PRO 254 0.0001

PRO 254 ASP 255 -0.0002

ASP 255 LEU 256 -0.0000

LEU 256 VAL 257 0.0002

VAL 257 LYS 258 0.0003

LYS 258 LEU 259 -0.0002

LEU 259 ASP 260 0.0003

ASP 260 ALA 261 -0.0082

ALA 261 ASN 262 -0.0000

ASN 262 GLY 263 -0.0000

GLY 263 ILE 264 0.0001

ILE 264 PHE 265 0.0001

PHE 265 SER 266 -0.0002

SER 266 HIS 267 0.0001

HIS 267 SER 268 -0.0001

SER 268 THR 269 -0.0002

THR 269 THR 270 0.0000

THR 270 LYS 271 -0.0001

LYS 271 ILE 272 -0.0001

ILE 272 GLY 273 0.0000

GLY 273 PHE 274 -0.0046

PHE 274 ARG 275 0.0002

ARG 275 ARG 276 -0.0002

ARG 276 SER 277 0.0003

SER 277 THR 278 0.0001

THR 278 PHE 279 -0.0000

PHE 279 LEU 280 -0.0000

LEU 280 ARG 281 0.0000

ARG 281 SER 282 0.0001

SER 282 TYR 283 -0.0003

TYR 283 MET 284 0.0002

MET 284 TYR 285 0.0001

TYR 285 ASP 286 -0.0001

ASP 286 PHE 287 -0.0032

PHE 287 ILE 288 -0.0001

ILE 288 GLN 289 -0.0000

GLN 289 ARG 290 0.0004

ARG 290 PHE 291 0.0002

PHE 291 ALA 292 -0.0001

ALA 292 PRO 293 0.0002

PRO 293 HIS 294 -0.0001

HIS 294 LEU 295 -0.0002

LEU 295 THR 296 -0.0001

THR 296 ARG 297 -0.0001

ARG 297 ASP 298 0.0001

ASP 298 VAL 299 -0.0002

VAL 299 VAL 300 0.0033

VAL 300 ASP 301 -0.0005

ASP 301 THR 302 0.0002

THR 302 ALA 303 0.0000

ALA 303 VAL 304 -0.0000

VAL 304 ALA 305 -0.0003

ALA 305 LEU 306 -0.0001

LEU 306 ARG 307 0.0002

ARG 307 SER 308 0.0001

SER 308 ASN 309 0.0001

ASN 309 GLU 310 -0.0000

GLU 310 ASP 311 0.0002

ASP 311 ILE 312 0.0001

ILE 312 GLU 313 0.0046

GLU 313 ALA 314 0.0003

ALA 314 MET 315 0.0003

MET 315 PHE 316 -0.0003

PHE 316 LYS 317 0.0001

LYS 317 ASP 318 0.0003

ASP 318 ILE 319 -0.0001

ILE 319 LYS 320 -0.0003

LYS 320 LEU 321 0.0001

LEU 321 PRO 322 -0.0004

PRO 322 GLU 323 0.0005

GLU 323 LYS 324 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** CysB ***

CA strain for 240125143252356257

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.

* CysB *