Should you encounter any unexpected behaviour,
please let us know.

* TLR4/MD2/Jor *

CA strain for 2403031259171421164

--- normal mode 10 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
PRO 27 CYS 28 0.0001

CYS 28 ILE 29 0.0001

ILE 29 GLU 30 0.0001

GLU 30 VAL 31 -0.0002

VAL 31 VAL 32 -0.0002

VAL 32 PRO 33 0.0001

PRO 33 ASN 34 -0.0004

ASN 34 ILE 35 -0.0005

ILE 35 THR 36 0.0002

THR 36 TYR 37 -0.0001

TYR 37 GLN 38 0.0000

GLN 38 CYS 39 0.0003

CYS 39 MET 40 0.0004

MET 40 ASP 41 0.0000

ASP 41 GLN 42 0.0003

GLN 42 LYS 43 -0.0008

LYS 43 LEU 44 0.0000

LEU 44 SER 45 0.0002

SER 45 LYS 46 -0.0001

LYS 46 VAL 47 0.0001

VAL 47 PRO 48 0.0005

PRO 48 ASP 49 -0.0003

ASP 49 ASP 50 -0.0002

ASP 50 ILE 51 0.0007

ILE 51 PRO 52 -0.0002

PRO 52 SER 53 0.0002

SER 53 SER 54 0.0001

SER 54 THR 55 -0.0000

THR 55 LYS 56 0.0000

LYS 56 ASN 57 0.0002

ASN 57 ILE 58 -0.0003

ILE 58 ASP 59 -0.0100

ASP 59 LEU 60 0.0001

LEU 60 SER 61 0.0000

SER 61 PHE 62 -0.0003

PHE 62 ASN 63 0.0003

ASN 63 PRO 64 -0.0001

PRO 64 LEU 65 0.0005

LEU 65 LYS 66 -0.0003

LYS 66 ILE 67 0.0031

ILE 67 LEU 68 -0.0000

LEU 68 LYS 69 -0.0002

LYS 69 SER 70 -0.0003

SER 70 TYR 71 0.0003

TYR 71 SER 72 0.0001

SER 72 PHE 73 0.0001

PHE 73 SER 74 -0.0001

SER 74 ASN 75 -0.0041

ASN 75 PHE 76 -0.0001

PHE 76 SER 77 0.0002

SER 77 GLU 78 -0.0001

GLU 78 LEU 79 -0.0002

LEU 79 GLN 80 0.0001

GLN 80 TRP 81 0.0000

TRP 81 LEU 82 0.0003

LEU 82 ASP 83 -0.0055

ASP 83 LEU 84 0.0001

LEU 84 SER 85 0.0000

SER 85 ARG 86 -0.0002

ARG 86 CYS 87 0.0003

CYS 87 GLU 88 -0.0002

GLU 88 ILE 89 0.0003

ILE 89 GLU 90 0.0003

GLU 90 THR 91 0.0036

THR 91 ILE 92 0.0002

ILE 92 GLU 93 -0.0001

GLU 93 ASP 94 0.0004

ASP 94 LYS 95 -0.0002

LYS 95 ALA 96 -0.0003

ALA 96 TRP 97 -0.0000

TRP 97 HIS 98 -0.0003

HIS 98 GLY 99 -0.0045

GLY 99 LEU 100 0.0002

LEU 100 HIS 101 -0.0000

HIS 101 HIS 102 0.0002

HIS 102 LEU 103 -0.0004

LEU 103 SER 104 0.0004

SER 104 ASN 105 0.0002

ASN 105 LEU 106 -0.0002

LEU 106 ILE 107 -0.0059

ILE 107 LEU 108 0.0001

LEU 108 THR 109 0.0001

THR 109 GLY 110 -0.0001

GLY 110 ASN 111 -0.0001

ASN 111 PRO 112 0.0002

PRO 112 ILE 113 0.0001

ILE 113 GLN 114 0.0002

GLN 114 SER 115 0.0035

SER 115 PHE 116 -0.0003

PHE 116 SER 117 0.0000

SER 117 PRO 118 0.0001

PRO 118 GLY 119 0.0000

GLY 119 SER 120 0.0004

SER 120 PHE 121 -0.0002

PHE 121 SER 122 -0.0000

SER 122 GLY 123 -0.0066

GLY 123 LEU 124 0.0002

LEU 124 THR 125 -0.0002

THR 125 SER 126 -0.0000

SER 126 LEU 127 -0.0000

LEU 127 GLU 128 -0.0003

GLU 128 ASN 129 0.0000

ASN 129 LEU 130 -0.0001

LEU 130 VAL 131 -0.0064

VAL 131 ALA 132 -0.0002

ALA 132 VAL 133 -0.0001

VAL 133 GLU 134 -0.0001

GLU 134 THR 135 0.0004

THR 135 LYS 136 0.0001

LYS 136 LEU 137 0.0001

LEU 137 ALA 138 -0.0002

ALA 138 SER 139 0.0017

SER 139 LEU 140 -0.0001

LEU 140 GLU 141 -0.0002

GLU 141 SER 142 -0.0003

SER 142 PHE 143 -0.0001

PHE 143 PRO 144 0.0002

PRO 144 ILE 145 0.0003

ILE 145 GLY 146 -0.0002

GLY 146 GLN 147 -0.0091

GLN 147 LEU 148 0.0000

LEU 148 ILE 149 -0.0002

ILE 149 THR 150 -0.0003

THR 150 LEU 151 0.0000

LEU 151 LYS 152 -0.0002

LYS 152 LYS 153 -0.0003

LYS 153 LEU 154 0.0001

LEU 154 ASN 155 -0.0082

ASN 155 VAL 156 -0.0001

VAL 156 ALA 157 0.0002

ALA 157 HIS 158 -0.0001

HIS 158 ASN 159 -0.0004

ASN 159 PHE 160 0.0002

PHE 160 ILE 161 0.0002

ILE 161 HIS 162 -0.0003

HIS 162 SER 163 -0.0021

SER 163 CYS 164 -0.0004

CYS 164 LYS 165 -0.0004

LYS 165 LEU 166 -0.0002

LEU 166 PRO 167 0.0003

PRO 167 ALA 168 -0.0003

ALA 168 TYR 169 -0.0003

TYR 169 PHE 170 -0.0001

PHE 170 SER 171 0.0020

SER 171 ASN 172 -0.0003

ASN 172 LEU 173 0.0005

LEU 173 THR 174 -0.0000

THR 174 ASN 175 0.0001

ASN 175 LEU 176 -0.0001

LEU 176 VAL 177 -0.0002

VAL 177 HIS 178 0.0001

HIS 178 VAL 179 0.0020

VAL 179 ASP 180 -0.0000

ASP 180 LEU 181 -0.0002

LEU 181 SER 182 -0.0001

SER 182 TYR 183 0.0001

TYR 183 ASN 184 -0.0004

ASN 184 TYR 185 0.0002

TYR 185 ILE 186 0.0002

ILE 186 GLN 187 -0.0087

GLN 187 THR 188 -0.0000

THR 188 ILE 189 0.0002

ILE 189 THR 190 -0.0001

THR 190 VAL 191 0.0001

VAL 191 ASN 192 -0.0000

ASN 192 ASP 193 0.0001

ASP 193 LEU 194 -0.0001

LEU 194 GLN 195 -0.0011

GLN 195 PHE 196 0.0002

PHE 196 LEU 197 0.0002

LEU 197 ARG 198 0.0003

ARG 198 GLU 199 -0.0003

GLU 199 ASN 200 0.0002

ASN 200 PRO 201 0.0001

PRO 201 GLN 202 -0.0000

GLN 202 VAL 203 -0.0069

VAL 203 ASN 204 0.0003

ASN 204 LEU 205 -0.0002

LEU 205 SER 206 -0.0001

SER 206 LEU 207 0.0003

LEU 207 ASP 208 0.0001

ASP 208 MET 209 -0.0000

MET 209 SER 210 -0.0003

SER 210 LEU 211 0.0013

LEU 211 ASN 212 -0.0000

ASN 212 PRO 213 0.0003

PRO 213 ILE 214 -0.0001

ILE 214 ASP 215 0.0001

ASP 215 PHE 216 0.0003

PHE 216 ILE 217 0.0001

ILE 217 GLN 218 -0.0002

GLN 218 ASP 219 0.0015

ASP 219 GLN 220 -0.0003

GLN 220 ALA 221 0.0002

ALA 221 PHE 222 -0.0001

PHE 222 GLN 223 0.0000

GLN 223 GLY 224 -0.0001

GLY 224 ILE 225 -0.0002

ILE 225 LYS 226 0.0001

LYS 226 LEU 227 -0.0116

LEU 227 HIS 228 0.0002

HIS 228 GLU 229 -0.0003

GLU 229 LEU 230 -0.0000

LEU 230 THR 231 0.0000

THR 231 LEU 232 0.0003

LEU 232 ARG 233 0.0000

ARG 233 GLY 234 -0.0004

GLY 234 ASN 235 0.0024

ASN 235 PHE 236 -0.0000

PHE 236 ASN 237 -0.0001

ASN 237 SER 238 0.0001

SER 238 SER 239 -0.0000

SER 239 ASN 240 -0.0000

ASN 240 ILE 241 0.0001

ILE 241 MET 242 0.0002

MET 242 LYS 243 -0.0019

LYS 243 THR 244 0.0003

THR 244 CYS 245 -0.0001

CYS 245 LEU 246 0.0000

LEU 246 GLN 247 -0.0002

GLN 247 ASN 248 0.0001

ASN 248 LEU 249 -0.0003

LEU 249 ALA 250 0.0000

ALA 250 GLY 251 0.0080

GLY 251 LEU 252 -0.0003

LEU 252 HIS 253 0.0000

HIS 253 VAL 254 0.0002

VAL 254 HIS 255 -0.0004

HIS 255 ARG 256 0.0001

ARG 256 LEU 257 -0.0001

LEU 257 ILE 258 -0.0001

ILE 258 LEU 259 0.0034

LEU 259 GLY 260 -0.0000

GLY 260 GLU 261 0.0003

GLU 261 PHE 262 -0.0004

PHE 262 LYS 263 0.0001

LYS 263 ASP 264 -0.0005

ASP 264 GLU 265 0.0002

GLU 265 ARG 266 -0.0002

ARG 266 ASN 267 0.0018

ASN 267 LEU 268 0.0001

LEU 268 GLU 269 0.0003

GLU 269 ILE 270 -0.0002

ILE 270 PHE 271 -0.0001

PHE 271 GLU 272 -0.0001

GLU 272 PRO 273 -0.0002

PRO 273 SER 274 0.0000

SER 274 ILE 275 0.0030

ILE 275 MET 276 -0.0001

MET 276 GLU 277 -0.0000

GLU 277 GLY 278 0.0000

GLY 278 LEU 279 0.0003

LEU 279 CYS 280 0.0000

CYS 280 ASP 281 -0.0002

ASP 281 VAL 282 0.0001

VAL 282 THR 283 -0.0047

THR 283 ILE 284 -0.0000

ILE 284 ASP 285 -0.0001

ASP 285 GLU 286 -0.0001

GLU 286 PHE 287 -0.0001

PHE 287 ARG 288 -0.0003

ARG 288 LEU 289 0.0002

LEU 289 THR 290 -0.0000

THR 290 TYR 291 -0.0031

TYR 291 THR 292 -0.0000

THR 292 ASN 293 0.0003

ASN 293 ASP 294 -0.0001

ASP 294 PHE 295 -0.0001

PHE 295 SER 296 -0.0003

SER 296 ASP 297 0.0001

ASP 297 ASP 298 0.0002

ASP 298 ILE 299 0.0163

ILE 299 VAL 300 -0.0004

VAL 300 LYS 301 0.0002

LYS 301 PHE 302 -0.0000

PHE 302 HIS 303 -0.0000

HIS 303 CYS 304 -0.0002

CYS 304 LEU 305 -0.0004

LEU 305 ALA 306 -0.0000

ALA 306 ASN 307 0.0020

ASN 307 VAL 308 0.0002

VAL 308 SER 309 0.0000

SER 309 ALA 310 0.0001

ALA 310 MET 311 0.0000

MET 311 SER 312 -0.0002

SER 312 LEU 313 -0.0002

LEU 313 ALA 314 0.0002

ALA 314 GLY 315 -0.0119

GLY 315 VAL 316 -0.0000

VAL 316 SER 317 0.0000

SER 317 ILE 318 0.0001

ILE 318 LYS 319 0.0001

LYS 319 TYR 320 0.0001

TYR 320 LEU 321 -0.0000

LEU 321 GLU 322 0.0002

GLU 322 ASP 323 0.0233

ASP 323 VAL 324 -0.0002

VAL 324 PRO 325 0.0004

PRO 325 LYS 326 -0.0004

LYS 326 HIS 327 -0.0001

HIS 327 PHE 328 0.0002

PHE 328 LYS 329 0.0000

LYS 329 TRP 330 0.0001

TRP 330 GLN 331 -0.0171

GLN 331 SER 332 0.0000

SER 332 LEU 333 0.0003

LEU 333 SER 334 -0.0002

SER 334 ILE 335 0.0001

ILE 335 ILE 336 -0.0002

ILE 336 ARG 337 0.0001

ARG 337 CYS 338 -0.0001

CYS 338 GLN 339 0.0159

GLN 339 LEU 340 -0.0005

LEU 340 LYS 341 0.0000

LYS 341 GLN 342 0.0002

GLN 342 PHE 343 0.0000

PHE 343 PRO 344 0.0001

PRO 344 THR 345 0.0002

THR 345 LEU 346 0.0002

LEU 346 ASP 347 0.0092

ASP 347 LEU 348 0.0001

LEU 348 PRO 349 0.0002

PRO 349 PHE 350 -0.0000

PHE 350 LEU 351 -0.0004

LEU 351 LYS 352 -0.0004

LYS 352 SER 353 -0.0001

SER 353 LEU 354 0.0001

LEU 354 THR 355 0.0099

THR 355 LEU 356 -0.0001

LEU 356 THR 357 0.0000

THR 357 MET 358 -0.0000

MET 358 ASN 359 0.0001

ASN 359 LYS 360 0.0003

LYS 360 GLY 361 -0.0000

GLY 361 SER 362 0.0000

SER 362 ILE 363 -0.0120

ILE 363 SER 364 0.0002

SER 364 PHE 365 -0.0000

PHE 365 LYS 366 0.0001

LYS 366 LYS 367 -0.0003

LYS 367 VAL 368 0.0002

VAL 368 ALA 369 -0.0001

ALA 369 LEU 370 -0.0001

LEU 370 PRO 371 0.0125

PRO 371 SER 372 -0.0002

SER 372 LEU 373 0.0003

LEU 373 SER 374 0.0001

SER 374 TYR 375 -0.0002

TYR 375 LEU 376 0.0001

LEU 376 ASP 377 -0.0000

ASP 377 LEU 378 -0.0004

LEU 378 SER 379 -0.0107

SER 379 ARG 380 0.0001

ARG 380 ASN 381 0.0003

ASN 381 ALA 382 0.0000

ALA 382 LEU 383 -0.0002

LEU 383 SER 384 -0.0001

SER 384 PHE 385 0.0002

PHE 385 SER 386 0.0001

SER 386 GLY 387 0.0006

GLY 387 CYS 388 -0.0001

CYS 388 CYS 389 0.0004

CYS 389 SER 390 0.0000

SER 390 TYR 391 -0.0004

TYR 391 SER 392 -0.0003

SER 392 ASP 393 0.0003

ASP 393 LEU 394 0.0002

LEU 394 GLY 395 0.0097

GLY 395 THR 396 -0.0001

THR 396 ASN 397 -0.0002

ASN 397 SER 398 -0.0001

SER 398 LEU 399 0.0002

LEU 399 ARG 400 -0.0001

ARG 400 HIS 401 -0.0002

HIS 401 LEU 402 0.0002

LEU 402 ASP 403 0.0005

ASP 403 LEU 404 0.0004

LEU 404 SER 405 -0.0002

SER 405 PHE 406 0.0001

PHE 406 ASN 407 -0.0001

ASN 407 GLY 408 0.0001

GLY 408 ALA 409 0.0001

ALA 409 ILE 410 0.0003

ILE 410 ILE 411 -0.0045

ILE 411 MET 412 0.0001

MET 412 SER 413 0.0002

SER 413 ALA 414 0.0001

ALA 414 ASN 415 -0.0001

ASN 415 PHE 416 -0.0000

PHE 416 MET 417 0.0000

MET 417 GLY 418 0.0001

GLY 418 LEU 419 0.0009

LEU 419 GLU 420 0.0002

GLU 420 GLU 421 -0.0003

GLU 421 LEU 422 0.0003

LEU 422 GLN 423 -0.0002

GLN 423 HIS 424 -0.0000

HIS 424 LEU 425 -0.0001

LEU 425 ASP 426 -0.0001

ASP 426 PHE 427 -0.0003

PHE 427 GLN 428 -0.0001

GLN 428 HIS 429 -0.0002

HIS 429 SER 430 0.0000

SER 430 THR 431 0.0002

THR 431 LEU 432 -0.0001

LEU 432 LYS 433 0.0001

LYS 433 ARG 434 0.0002

ARG 434 VAL 435 -0.0175

VAL 435 THR 436 0.0002

THR 436 GLU 437 0.0004

GLU 437 PHE 438 -0.0004

PHE 438 SER 439 0.0002

SER 439 ALA 440 -0.0003

ALA 440 PHE 441 -0.0001

PHE 441 LEU 442 0.0004

LEU 442 SER 443 -0.0078

SER 443 LEU 444 0.0000

LEU 444 GLU 445 0.0002

GLU 445 LYS 446 0.0001

LYS 446 LEU 447 -0.0001

LEU 447 LEU 448 0.0002

LEU 448 TYR 449 0.0000

TYR 449 LEU 450 -0.0004

LEU 450 ASP 451 -0.0017

ASP 451 ILE 452 0.0004

ILE 452 SER 453 0.0002

SER 453 TYR 454 0.0002

TYR 454 THR 455 0.0000

THR 455 ASN 456 -0.0002

ASN 456 THR 457 0.0001

THR 457 LYS 458 0.0002

LYS 458 ILE 459 0.0087

ILE 459 ASP 460 0.0004

ASP 460 PHE 461 0.0002

PHE 461 ASP 462 0.0000

ASP 462 GLY 463 -0.0001

GLY 463 ILE 464 -0.0003

ILE 464 PHE 465 0.0001

PHE 465 LEU 466 0.0002

LEU 466 GLY 467 -0.0193

GLY 467 LEU 468 -0.0002

LEU 468 THR 469 -0.0003

THR 469 SER 470 0.0001

SER 470 LEU 471 0.0000

LEU 471 ASN 472 0.0000

ASN 472 THR 473 0.0003

THR 473 LEU 474 0.0001

LEU 474 LYS 475 0.0079

LYS 475 MET 476 0.0004

MET 476 ALA 477 -0.0001

ALA 477 GLY 478 0.0001

GLY 478 ASN 479 -0.0005

ASN 479 SER 480 0.0004

SER 480 PHE 481 0.0001

PHE 481 LYS 482 -0.0000

LYS 482 ASP 483 0.0049

ASP 483 ASN 484 -0.0003

ASN 484 THR 485 0.0001

THR 485 LEU 486 0.0001

LEU 486 SER 487 0.0001

SER 487 ASN 488 -0.0002

ASN 488 VAL 489 0.0001

VAL 489 PHE 490 0.0001

PHE 490 ALA 491 0.0057

ALA 491 ASN 492 0.0001

ASN 492 THR 493 0.0001

THR 493 THR 494 0.0002

THR 494 ASN 495 -0.0000

ASN 495 LEU 496 0.0002

LEU 496 THR 497 0.0002

THR 497 PHE 498 -0.0002

PHE 498 LEU 499 0.0010

LEU 499 ASP 500 0.0000

ASP 500 LEU 501 0.0002

LEU 501 SER 502 -0.0000

SER 502 LYS 503 0.0002

LYS 503 CYS 504 0.0000

CYS 504 GLN 505 0.0002

GLN 505 LEU 506 0.0001

LEU 506 GLU 507 -0.0104

GLU 507 GLN 508 -0.0002

GLN 508 ILE 509 0.0002

ILE 509 SER 510 0.0002

SER 510 TRP 511 0.0000

TRP 511 GLY 512 0.0000

GLY 512 VAL 513 -0.0000

VAL 513 PHE 514 0.0004

PHE 514 ASP 515 0.0002

ASP 515 THR 516 -0.0000

THR 516 LEU 517 -0.0001

LEU 517 HIS 518 0.0002

HIS 518 ARG 519 -0.0001

ARG 519 LEU 520 -0.0002

LEU 520 GLN 521 0.0003

GLN 521 LEU 522 0.0001

LEU 522 LEU 523 -0.0044

LEU 523 ASN 524 -0.0002

ASN 524 MET 525 0.0002

MET 525 SER 526 -0.0002

SER 526 HIS 527 -0.0001

HIS 527 ASN 528 -0.0004

ASN 528 ASN 529 0.0000

ASN 529 LEU 530 -0.0002

LEU 530 LEU 531 -0.0084

LEU 531 PHE 532 0.0002

PHE 532 LEU 533 0.0000

LEU 533 ASP 534 -0.0002

ASP 534 SER 535 0.0003

SER 535 SER 536 0.0003

SER 536 HIS 537 -0.0000

HIS 537 TYR 538 0.0003

TYR 538 ASN 539 0.0003

ASN 539 GLN 540 -0.0000

GLN 540 LEU 541 -0.0001

LEU 541 TYR 542 0.0001

TYR 542 SER 543 -0.0004

SER 543 LEU 544 0.0004

LEU 544 SER 545 -0.0002

SER 545 THR 546 -0.0002

THR 546 LEU 547 -0.0020

LEU 547 ASP 548 0.0004

ASP 548 CYS 549 -0.0002

CYS 549 SER 550 0.0002

SER 550 PHE 551 -0.0001

PHE 551 ASN 552 0.0002

ASN 552 ARG 553 -0.0001

ARG 553 ILE 554 -0.0000

ILE 554 GLU 555 0.0039

GLU 555 THR 556 -0.0000

THR 556 SER 557 -0.0002

SER 557 LYS 558 0.0002

LYS 558 GLY 559 0.0000

GLY 559 ILE 560 -0.0001

ILE 560 LEU 561 0.0003

LEU 561 GLN 562 0.0002

GLN 562 HIS 563 -0.0050

HIS 563 PHE 564 0.0001

PHE 564 PRO 565 -0.0005

PRO 565 LYS 566 0.0002

LYS 566 SER 567 0.0003

SER 567 LEU 568 0.0000

LEU 568 ALA 569 0.0001

ALA 569 PHE 570 -0.0002

PHE 570 PHE 571 -0.0022

PHE 571 ASN 572 0.0003

ASN 572 LEU 573 0.0001

LEU 573 THR 574 -0.0002

THR 574 ASN 575 0.0000

ASN 575 ASN 576 -0.0003

ASN 576 SER 577 -0.0000

SER 577 VAL 578 0.0002

VAL 578 ALA 579 0.0062

ALA 579 CYS 580 -0.0003

CYS 580 ILE 581 0.0002

ILE 581 CYS 582 -0.0003

CYS 582 GLU 583 -0.0000

GLU 583 HIS 584 0.0002

HIS 584 GLN 585 -0.0001

GLN 585 LYS 586 -0.0001

LYS 586 PHE 587 0.0002

PHE 587 LEU 588 -0.0003

LEU 588 GLN 589 -0.0001

GLN 589 TRP 590 -0.0000

TRP 590 VAL 591 0.0001

VAL 591 LYS 592 0.0003

LYS 592 GLU 593 -0.0002

GLU 593 GLN 594 -0.0000

GLN 594 LYS 595 -0.0047

LYS 595 GLN 596 0.0004

GLN 596 PHE 597 -0.0002

PHE 597 LEU 598 0.0001

LEU 598 VAL 599 -0.0003

VAL 599 ASN 600 0.0000

ASN 600 VAL 601 0.0003

VAL 601 GLU 602 -0.0001

GLU 602 GLN 603 -0.0046

GLN 603 MET 604 0.0004

MET 604 THR 605 0.0002

THR 605 CYS 606 -0.0004

CYS 606 ALA 607 0.0001

ALA 607 THR 608 -0.0002

THR 608 PRO 609 0.0002

PRO 609 ASN 613 -0.0002

ASN 613 THR 614 -0.0001

THR 614 SER 615 0.0004

SER 615 LEU 616 -0.0001

LEU 616 VAL 617 0.0003

VAL 617 LEU 618 0.0001

LEU 618 ASP 619 0.0003

ASP 619 PHE 620 -0.0002

PHE 620 ASN 621 0.0033

ASN 621 ASN 622 -0.0003

ASN 622 SER 623 -0.0000

SER 623 THR 624 -0.0002

THR 624 CYS 625 0.0000

CYS 625 GLN 21 0.0536

GLN 21 GLN 22 -0.0000

GLN 22 TRP 23 0.0002

TRP 23 PHE 24 0.0002

PHE 24 CYS 25 -0.0003

CYS 25 ASN 26 -0.0002

ASN 26 SER 27 0.0001

SER 27 SER 28 -0.0001

SER 28 ASP 29 0.0021

ASP 29 ALA 30 -0.0000

ALA 30 ILE 31 0.0001

ILE 31 ILE 32 -0.0003

ILE 32 SER 33 0.0001

SER 33 TYR 34 -0.0004

TYR 34 SER 35 0.0004

SER 35 TYR 36 -0.0002

TYR 36 CYS 37 0.0059

CYS 37 ASP 38 -0.0002

ASP 38 HIS 39 0.0001

HIS 39 LEU 40 0.0001

LEU 40 LYS 41 0.0003

LYS 41 PHE 42 -0.0002

PHE 42 PRO 43 0.0002

PRO 43 ILE 44 0.0000

ILE 44 SER 45 0.0001

SER 45 ILE 46 0.0004

ILE 46 SER 47 -0.0002

SER 47 SER 48 0.0001

SER 48 GLU 49 0.0002

GLU 49 PRO 50 0.0002

PRO 50 CYS 51 0.0000

CYS 51 ILE 52 -0.0001

ILE 52 ARG 53 -0.0051

ARG 53 LEU 54 -0.0001

LEU 54 ARG 55 0.0001

ARG 55 GLY 56 -0.0003

GLY 56 THR 57 0.0001

THR 57 ASN 58 0.0005

ASN 58 GLY 59 -0.0002

GLY 59 PHE 60 0.0003

PHE 60 VAL 61 -0.0122

VAL 61 HIS 62 0.0003

HIS 62 VAL 63 0.0002

VAL 63 GLU 64 -0.0003

GLU 64 PHE 65 -0.0000

PHE 65 ILE 66 0.0001

ILE 66 PRO 67 -0.0003

PRO 67 ARG 68 -0.0002

ARG 68 GLY 69 0.0378

GLY 69 ASN 70 0.0001

ASN 70 LEU 71 -0.0003

LEU 71 LYS 72 -0.0002

LYS 72 TYR 73 0.0003

TYR 73 LEU 74 0.0003

LEU 74 TYR 75 0.0000

TYR 75 PHE 76 -0.0001

PHE 76 ASN 77 -0.0265

ASN 77 LEU 78 0.0003

LEU 78 PHE 79 0.0003

PHE 79 ILE 80 0.0002

ILE 80 SER 81 0.0001

SER 81 VAL 82 0.0003

VAL 82 ASN 83 -0.0000

ASN 83 SER 84 0.0001

SER 84 ILE 85 0.0158

ILE 85 GLU 86 -0.0002

GLU 86 LEU 87 0.0003

LEU 87 PRO 88 -0.0004

PRO 88 LYS 89 0.0001

LYS 89 ARG 90 -0.0001

ARG 90 LYS 91 0.0002

LYS 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0542

VAL 93 LEU 94 -0.0002

LEU 94 CYS 95 -0.0003

CYS 95 HIS 96 0.0003

HIS 96 GLY 97 -0.0002

GLY 97 HIS 98 0.0000

HIS 98 ASP 99 -0.0002

ASP 99 ASP 100 0.0002

ASP 100 ASP 101 -0.0149

ASP 101 TYR 102 -0.0001

TYR 102 SER 103 -0.0002

SER 103 PHE 104 -0.0002

PHE 104 CYS 105 -0.0003

CYS 105 ARG 106 0.0001

ARG 106 ALA 107 -0.0001

ALA 107 LEU 108 0.0000

LEU 108 LYS 109 0.0238

LYS 109 GLY 110 0.0002

GLY 110 GLU 111 -0.0004

GLU 111 THR 112 0.0001

THR 112 VAL 113 -0.0003

VAL 113 ASN 114 -0.0000

ASN 114 THR 115 -0.0000

THR 115 SER 116 0.0002

SER 116 ILE 117 0.0092

ILE 117 PRO 118 -0.0000

PRO 118 PHE 119 0.0000

PHE 119 SER 120 0.0002

SER 120 PHE 121 -0.0002

PHE 121 GLU 122 0.0002

GLU 122 GLY 123 0.0002

GLY 123 ILE 124 0.0001

ILE 124 LEU 125 0.0197

LEU 125 PHE 126 0.0002

PHE 126 PRO 127 0.0001

PRO 127 LYS 128 -0.0002

LYS 128 GLY 129 0.0001

GLY 129 HIS 130 0.0001

HIS 130 TYR 131 -0.0002

TYR 131 ARG 132 0.0001

ARG 132 CYS 133 -0.0066

CYS 133 VAL 134 -0.0003

VAL 134 ALA 135 -0.0001

ALA 135 GLU 136 -0.0003

GLU 136 ALA 137 0.0001

ALA 137 ILE 138 0.0002

ILE 138 ALA 139 -0.0002

ALA 139 GLY 140 -0.0002

GLY 140 ASP 141 -0.0063

ASP 141 THR 142 -0.0004

THR 142 GLU 143 0.0003

GLU 143 GLU 144 -0.0004

GLU 144 LYS 145 0.0000

LYS 145 LEU 146 0.0002

LEU 146 PHE 147 -0.0001

PHE 147 CYS 148 -0.0001

CYS 148 LEU 149 -0.0072

LEU 149 ASN 150 0.0001

ASN 150 PHE 151 -0.0002

PHE 151 THR 152 -0.0001

THR 152 ILE 153 0.0002

ILE 153 ILE 154 0.0001

ILE 154 HIS 155 0.0001

HIS 155 PRO 27 0.0382

PRO 27 CYS 28 0.0003

CYS 28 ILE 29 -0.0001

ILE 29 GLU 30 -0.0000

GLU 30 VAL 31 0.0000

VAL 31 VAL 32 -0.0005

VAL 32 PRO 33 0.0000

PRO 33 ASN 34 -0.0001

ASN 34 ILE 35 -0.0003

ILE 35 THR 36 -0.0002

THR 36 TYR 37 0.0002

TYR 37 GLN 38 -0.0002

GLN 38 CYS 39 0.0001

CYS 39 MET 40 0.0001

MET 40 ASP 41 0.0001

ASP 41 GLN 42 0.0000

GLN 42 LYS 43 -0.0011

LYS 43 LEU 44 0.0002

LEU 44 SER 45 0.0002

SER 45 LYS 46 -0.0001

LYS 46 VAL 47 0.0002

VAL 47 PRO 48 0.0000

PRO 48 ASP 49 0.0004

ASP 49 ASP 50 -0.0001

ASP 50 ILE 51 -0.0003

ILE 51 PRO 52 -0.0002

PRO 52 SER 53 -0.0003

SER 53 SER 54 0.0002

SER 54 THR 55 -0.0005

THR 55 LYS 56 0.0001

LYS 56 ASN 57 0.0001

ASN 57 ILE 58 -0.0000

ILE 58 ASP 59 -0.0060

ASP 59 LEU 60 -0.0001

LEU 60 SER 61 -0.0001

SER 61 PHE 62 -0.0001

PHE 62 ASN 63 -0.0000

ASN 63 PRO 64 0.0001

PRO 64 LEU 65 0.0003

LEU 65 LYS 66 0.0002

LYS 66 ILE 67 0.0041

ILE 67 LEU 68 -0.0000

LEU 68 LYS 69 0.0002

LYS 69 SER 70 0.0002

SER 70 TYR 71 -0.0001

TYR 71 SER 72 -0.0002

SER 72 PHE 73 -0.0001

PHE 73 SER 74 -0.0004

SER 74 ASN 75 -0.0060

ASN 75 PHE 76 -0.0000

PHE 76 SER 77 0.0001

SER 77 GLU 78 0.0002

GLU 78 LEU 79 -0.0000

LEU 79 GLN 80 -0.0004

GLN 80 TRP 81 -0.0003

TRP 81 LEU 82 0.0003

LEU 82 ASP 83 -0.0028

ASP 83 LEU 84 0.0001

LEU 84 SER 85 -0.0001

SER 85 ARG 86 0.0001

ARG 86 CYS 87 0.0001

CYS 87 GLU 88 0.0001

GLU 88 ILE 89 0.0003

ILE 89 GLU 90 -0.0004

GLU 90 THR 91 0.0021

THR 91 ILE 92 -0.0001

ILE 92 GLU 93 -0.0001

GLU 93 ASP 94 -0.0003

ASP 94 LYS 95 0.0003

LYS 95 ALA 96 -0.0001

ALA 96 TRP 97 0.0002

TRP 97 HIS 98 -0.0004

HIS 98 GLY 99 -0.0047

GLY 99 LEU 100 0.0003

LEU 100 HIS 101 -0.0000

HIS 101 HIS 102 -0.0002

HIS 102 LEU 103 0.0003

LEU 103 SER 104 -0.0003

SER 104 ASN 105 0.0003

ASN 105 LEU 106 0.0002

LEU 106 ILE 107 -0.0029

ILE 107 LEU 108 -0.0002

LEU 108 THR 109 0.0003

THR 109 GLY 110 -0.0002

GLY 110 ASN 111 0.0001

ASN 111 PRO 112 -0.0001

PRO 112 ILE 113 0.0002

ILE 113 GLN 114 -0.0000

GLN 114 SER 115 0.0015

SER 115 PHE 116 0.0001

PHE 116 SER 117 0.0002

SER 117 PRO 118 -0.0001

PRO 118 GLY 119 0.0001

GLY 119 SER 120 -0.0003

SER 120 PHE 121 0.0002

PHE 121 SER 122 0.0000

SER 122 GLY 123 -0.0065

GLY 123 LEU 124 0.0002

LEU 124 THR 125 -0.0001

THR 125 SER 126 -0.0001

SER 126 LEU 127 0.0002

LEU 127 GLU 128 0.0001

GLU 128 ASN 129 -0.0004

ASN 129 LEU 130 0.0001

LEU 130 VAL 131 -0.0032

VAL 131 ALA 132 -0.0001

ALA 132 VAL 133 0.0000

VAL 133 GLU 134 -0.0001

GLU 134 THR 135 -0.0000

THR 135 LYS 136 0.0001

LYS 136 LEU 137 0.0005

LEU 137 ALA 138 0.0003

ALA 138 SER 139 0.0023

SER 139 LEU 140 -0.0000

LEU 140 GLU 141 0.0001

GLU 141 SER 142 -0.0002

SER 142 PHE 143 0.0004

PHE 143 PRO 144 0.0002

PRO 144 ILE 145 0.0000

ILE 145 GLY 146 0.0003

GLY 146 GLN 147 -0.0084

GLN 147 LEU 148 -0.0003

LEU 148 ILE 149 0.0002

ILE 149 THR 150 0.0000

THR 150 LEU 151 0.0003

LEU 151 LYS 152 -0.0003

LYS 152 LYS 153 -0.0003

LYS 153 LEU 154 0.0003

LEU 154 ASN 155 -0.0055

ASN 155 VAL 156 -0.0004

VAL 156 ALA 157 0.0001

ALA 157 HIS 158 -0.0004

HIS 158 ASN 159 -0.0000

ASN 159 PHE 160 0.0001

PHE 160 ILE 161 0.0003

ILE 161 HIS 162 0.0001

HIS 162 SER 163 0.0003

SER 163 CYS 164 0.0002

CYS 164 LYS 165 -0.0003

LYS 165 LEU 166 0.0003

LEU 166 PRO 167 0.0000

PRO 167 ALA 168 0.0002

ALA 168 TYR 169 -0.0003

TYR 169 PHE 170 0.0002

PHE 170 SER 171 0.0019

SER 171 ASN 172 -0.0006

ASN 172 LEU 173 0.0000

LEU 173 THR 174 -0.0001

THR 174 ASN 175 -0.0001

ASN 175 LEU 176 -0.0003

LEU 176 VAL 177 -0.0002

VAL 177 HIS 178 0.0001

HIS 178 VAL 179 0.0008

VAL 179 ASP 180 -0.0001

ASP 180 LEU 181 -0.0002

LEU 181 SER 182 0.0001

SER 182 TYR 183 0.0001

TYR 183 ASN 184 -0.0001

ASN 184 TYR 185 -0.0000

TYR 185 ILE 186 -0.0000

ILE 186 GLN 187 -0.0084

GLN 187 THR 188 0.0000

THR 188 ILE 189 -0.0001

ILE 189 THR 190 0.0001

THR 190 VAL 191 0.0002

VAL 191 ASN 192 -0.0001

ASN 192 ASP 193 0.0004

ASP 193 LEU 194 -0.0004

LEU 194 GLN 195 -0.0011

GLN 195 PHE 196 -0.0000

PHE 196 LEU 197 -0.0003

LEU 197 ARG 198 -0.0001

ARG 198 GLU 199 -0.0000

GLU 199 ASN 200 0.0002

ASN 200 PRO 201 0.0001

PRO 201 GLN 202 -0.0001

GLN 202 VAL 203 -0.0074

VAL 203 ASN 204 -0.0001

ASN 204 LEU 205 -0.0002

LEU 205 SER 206 0.0004

SER 206 LEU 207 -0.0001

LEU 207 ASP 208 0.0002

ASP 208 MET 209 -0.0003

MET 209 SER 210 0.0001

SER 210 LEU 211 0.0014

LEU 211 ASN 212 -0.0002

ASN 212 PRO 213 0.0003

PRO 213 ILE 214 -0.0003

ILE 214 ASP 215 0.0001

ASP 215 PHE 216 -0.0002

PHE 216 ILE 217 0.0006

ILE 217 GLN 218 0.0002

GLN 218 ASP 219 0.0026

ASP 219 GLN 220 0.0000

GLN 220 ALA 221 0.0000

ALA 221 PHE 222 0.0001

PHE 222 GLN 223 -0.0001

GLN 223 GLY 224 0.0000

GLY 224 ILE 225 -0.0003

ILE 225 LYS 226 0.0000

LYS 226 LEU 227 -0.0088

LEU 227 HIS 228 0.0003

HIS 228 GLU 229 -0.0004

GLU 229 LEU 230 0.0001

LEU 230 THR 231 -0.0003

THR 231 LEU 232 -0.0000

LEU 232 ARG 233 -0.0000

ARG 233 GLY 234 0.0001

GLY 234 ASN 235 0.0039

ASN 235 PHE 236 0.0000

PHE 236 ASN 237 -0.0002

ASN 237 SER 238 -0.0003

SER 238 SER 239 0.0003

SER 239 ASN 240 -0.0002

ASN 240 ILE 241 0.0003

ILE 241 MET 242 -0.0002

MET 242 LYS 243 -0.0005

LYS 243 THR 244 0.0005

THR 244 CYS 245 0.0002

CYS 245 LEU 246 -0.0002

LEU 246 GLN 247 -0.0002

GLN 247 ASN 248 -0.0002

ASN 248 LEU 249 0.0001

LEU 249 ALA 250 -0.0000

ALA 250 GLY 251 0.0037

GLY 251 LEU 252 0.0001

LEU 252 HIS 253 0.0001

HIS 253 VAL 254 0.0000

VAL 254 HIS 255 0.0002

HIS 255 ARG 256 0.0002

ARG 256 LEU 257 -0.0002

LEU 257 ILE 258 -0.0002

ILE 258 LEU 259 0.0008

LEU 259 GLY 260 -0.0000

GLY 260 GLU 261 0.0006

GLU 261 PHE 262 -0.0003

PHE 262 LYS 263 0.0005

LYS 263 ASP 264 0.0003

ASP 264 GLU 265 -0.0000

GLU 265 ARG 266 0.0001

ARG 266 ASN 267 -0.0190

ASN 267 LEU 268 -0.0002

LEU 268 GLU 269 0.0002

GLU 269 ILE 270 -0.0001

ILE 270 PHE 271 -0.0001

PHE 271 GLU 272 0.0004

GLU 272 PRO 273 -0.0000

PRO 273 SER 274 -0.0002

SER 274 ILE 275 0.0002

ILE 275 MET 276 0.0001

MET 276 GLU 277 -0.0004

GLU 277 GLY 278 -0.0003

GLY 278 LEU 279 0.0003

LEU 279 CYS 280 0.0003

CYS 280 ASP 281 -0.0001

ASP 281 VAL 282 0.0000

VAL 282 THR 283 -0.0021

THR 283 ILE 284 -0.0004

ILE 284 ASP 285 0.0003

ASP 285 GLU 286 -0.0000

GLU 286 PHE 287 -0.0000

PHE 287 ARG 288 -0.0001

ARG 288 LEU 289 -0.0001

LEU 289 THR 290 0.0002

THR 290 TYR 291 -0.0003

TYR 291 THR 292 0.0001

THR 292 ASN 293 0.0002

ASN 293 ASP 294 0.0000

ASP 294 PHE 295 0.0003

PHE 295 SER 296 -0.0001

SER 296 ASP 297 -0.0000

ASP 297 ASP 298 0.0002

ASP 298 ILE 299 0.0153

ILE 299 VAL 300 0.0000

VAL 300 LYS 301 -0.0003

LYS 301 PHE 302 -0.0000

PHE 302 HIS 303 -0.0003

HIS 303 CYS 304 0.0004

CYS 304 LEU 305 0.0001

LEU 305 ALA 306 -0.0002

ALA 306 ASN 307 0.0021

ASN 307 VAL 308 -0.0006

VAL 308 SER 309 0.0001

SER 309 ALA 310 0.0002

ALA 310 MET 311 -0.0001

MET 311 SER 312 -0.0003

SER 312 LEU 313 -0.0000

LEU 313 ALA 314 0.0002

ALA 314 GLY 315 -0.0113

GLY 315 VAL 316 -0.0000

VAL 316 SER 317 -0.0000

SER 317 ILE 318 -0.0003

ILE 318 LYS 319 0.0004

LYS 319 TYR 320 -0.0001

TYR 320 LEU 321 0.0000

LEU 321 GLU 322 -0.0001

GLU 322 ASP 323 0.0150

ASP 323 VAL 324 -0.0002

VAL 324 PRO 325 0.0004

PRO 325 LYS 326 0.0002

LYS 326 HIS 327 -0.0003

HIS 327 PHE 328 -0.0003

PHE 328 LYS 329 0.0003

LYS 329 TRP 330 0.0001

TRP 330 GLN 331 -0.0125

GLN 331 SER 332 0.0002

SER 332 LEU 333 -0.0001

LEU 333 SER 334 0.0005

SER 334 ILE 335 0.0000

ILE 335 ILE 336 0.0002

ILE 336 ARG 337 0.0001

ARG 337 CYS 338 -0.0001

CYS 338 GLN 339 0.0083

GLN 339 LEU 340 0.0003

LEU 340 LYS 341 0.0000

LYS 341 GLN 342 0.0001

GLN 342 PHE 343 -0.0003

PHE 343 PRO 344 0.0002

PRO 344 THR 345 0.0002

THR 345 LEU 346 0.0004

LEU 346 ASP 347 0.0021

ASP 347 LEU 348 0.0000

LEU 348 PRO 349 -0.0002

PRO 349 PHE 350 0.0002

PHE 350 LEU 351 0.0002

LEU 351 LYS 352 -0.0002

LYS 352 SER 353 0.0002

SER 353 LEU 354 -0.0004

LEU 354 THR 355 0.0046

THR 355 LEU 356 -0.0004

LEU 356 THR 357 0.0005

THR 357 MET 358 -0.0001

MET 358 ASN 359 -0.0004

ASN 359 LYS 360 -0.0004

LYS 360 GLY 361 0.0000

GLY 361 SER 362 -0.0001

SER 362 ILE 363 -0.0092

ILE 363 SER 364 0.0001

SER 364 PHE 365 -0.0001

PHE 365 LYS 366 -0.0002

LYS 366 LYS 367 0.0003

LYS 367 VAL 368 -0.0000

VAL 368 ALA 369 0.0002

ALA 369 LEU 370 -0.0002

LEU 370 PRO 371 0.0131

PRO 371 SER 372 0.0002

SER 372 LEU 373 0.0000

LEU 373 SER 374 0.0003

SER 374 TYR 375 -0.0001

TYR 375 LEU 376 -0.0002

LEU 376 ASP 377 0.0002

ASP 377 LEU 378 -0.0001

LEU 378 SER 379 -0.0096

SER 379 ARG 380 -0.0002

ARG 380 ASN 381 0.0001

ASN 381 ALA 382 -0.0000

ALA 382 LEU 383 -0.0003

LEU 383 SER 384 0.0003

SER 384 PHE 385 0.0001

PHE 385 SER 386 -0.0000

SER 386 GLY 387 0.0080

GLY 387 CYS 388 -0.0001

CYS 388 CYS 389 -0.0001

CYS 389 SER 390 0.0000

SER 390 TYR 391 0.0000

TYR 391 SER 392 0.0005

SER 392 ASP 393 0.0003

ASP 393 LEU 394 0.0003

LEU 394 GLY 395 0.0040

GLY 395 THR 396 -0.0000

THR 396 ASN 397 0.0002

ASN 397 SER 398 0.0002

SER 398 LEU 399 0.0000

LEU 399 ARG 400 -0.0001

ARG 400 HIS 401 -0.0002

HIS 401 LEU 402 0.0001

LEU 402 ASP 403 -0.0039

ASP 403 LEU 404 0.0000

LEU 404 SER 405 0.0003

SER 405 PHE 406 0.0000

PHE 406 ASN 407 0.0000

ASN 407 GLY 408 0.0005

GLY 408 ALA 409 -0.0002

ALA 409 ILE 410 0.0004

ILE 410 ILE 411 -0.0020

ILE 411 MET 412 -0.0001

MET 412 SER 413 -0.0000

SER 413 ALA 414 0.0001

ALA 414 ASN 415 0.0001

ASN 415 PHE 416 -0.0002

PHE 416 MET 417 -0.0000

MET 417 GLY 418 0.0001

GLY 418 LEU 419 0.0007

LEU 419 GLU 420 0.0002

GLU 420 GLU 421 0.0003

GLU 421 LEU 422 -0.0001

LEU 422 GLN 423 -0.0001

GLN 423 HIS 424 -0.0002

HIS 424 LEU 425 0.0001

LEU 425 ASP 426 0.0001

ASP 426 PHE 427 -0.0012

PHE 427 GLN 428 -0.0000

GLN 428 HIS 429 -0.0002

HIS 429 SER 430 -0.0001

SER 430 THR 431 0.0000

THR 431 LEU 432 -0.0001

LEU 432 LYS 433 -0.0003

LYS 433 ARG 434 0.0001

ARG 434 VAL 435 -0.0155

VAL 435 THR 436 0.0001

THR 436 GLU 437 0.0001

GLU 437 PHE 438 0.0002

PHE 438 SER 439 -0.0000

SER 439 ALA 440 0.0003

ALA 440 PHE 441 0.0002

PHE 441 LEU 442 -0.0002

LEU 442 SER 443 -0.0178

SER 443 LEU 444 -0.0003

LEU 444 GLU 445 0.0001

GLU 445 LYS 446 0.0002

LYS 446 LEU 447 -0.0002

LEU 447 LEU 448 0.0002

LEU 448 TYR 449 -0.0002

TYR 449 LEU 450 0.0001

LEU 450 ASP 451 -0.0034

ASP 451 ILE 452 0.0000

ILE 452 SER 453 0.0000

SER 453 TYR 454 0.0001

TYR 454 THR 455 0.0001

THR 455 ASN 456 -0.0001

ASN 456 THR 457 0.0002

THR 457 LYS 458 -0.0000

LYS 458 ILE 459 0.0184

ILE 459 ASP 460 -0.0002

ASP 460 PHE 461 0.0001

PHE 461 ASP 462 0.0003

ASP 462 GLY 463 -0.0002

GLY 463 ILE 464 0.0001

ILE 464 PHE 465 -0.0002

PHE 465 LEU 466 -0.0001

LEU 466 GLY 467 -0.0244

GLY 467 LEU 468 -0.0001

LEU 468 THR 469 -0.0001

THR 469 SER 470 0.0001

SER 470 LEU 471 0.0001

LEU 471 ASN 472 0.0001

ASN 472 THR 473 -0.0003

THR 473 LEU 474 0.0001

LEU 474 LYS 475 0.0049

LYS 475 MET 476 0.0001

MET 476 ALA 477 0.0000

ALA 477 GLY 478 0.0000

GLY 478 ASN 479 0.0000

ASN 479 SER 480 -0.0001

SER 480 PHE 481 0.0002

PHE 481 LYS 482 -0.0000

LYS 482 ASP 483 -0.0102

ASP 483 ASN 484 0.0000

ASN 484 THR 485 -0.0000

THR 485 LEU 486 -0.0001

LEU 486 SER 487 0.0001

SER 487 ASN 488 -0.0002

ASN 488 VAL 489 0.0001

VAL 489 PHE 490 0.0004

PHE 490 ALA 491 0.0115

ALA 491 ASN 492 0.0000

ASN 492 THR 493 0.0002

THR 493 THR 494 0.0004

THR 494 ASN 495 -0.0004

ASN 495 LEU 496 -0.0000

LEU 496 THR 497 0.0003

THR 497 PHE 498 -0.0001

PHE 498 LEU 499 -0.0024

LEU 499 ASP 500 -0.0003

ASP 500 LEU 501 0.0001

LEU 501 SER 502 0.0001

SER 502 LYS 503 -0.0000

LYS 503 CYS 504 0.0002

CYS 504 GLN 505 0.0001

GLN 505 LEU 506 -0.0003

LEU 506 GLU 507 -0.0007

GLU 507 GLN 508 0.0000

GLN 508 ILE 509 0.0002

ILE 509 SER 510 -0.0001

SER 510 TRP 511 0.0001

TRP 511 GLY 512 0.0000

GLY 512 VAL 513 -0.0004

VAL 513 PHE 514 -0.0002

PHE 514 ASP 515 -0.0010

ASP 515 THR 516 0.0001

THR 516 LEU 517 0.0002

LEU 517 HIS 518 -0.0003

HIS 518 ARG 519 0.0004

ARG 519 LEU 520 -0.0003

LEU 520 GLN 521 -0.0002

GLN 521 LEU 522 0.0003

LEU 522 LEU 523 -0.0071

LEU 523 ASN 524 -0.0002

ASN 524 MET 525 0.0000

MET 525 SER 526 0.0000

SER 526 HIS 527 -0.0003

HIS 527 ASN 528 0.0001

ASN 528 ASN 529 -0.0002

ASN 529 LEU 530 0.0001

LEU 530 LEU 531 -0.0064

LEU 531 PHE 532 0.0000

PHE 532 LEU 533 -0.0002

LEU 533 ASP 534 0.0001

ASP 534 SER 535 0.0000

SER 535 SER 536 0.0002

SER 536 HIS 537 0.0001

HIS 537 TYR 538 0.0000

TYR 538 ASN 539 -0.0001

ASN 539 GLN 540 0.0002

GLN 540 LEU 541 0.0005

LEU 541 TYR 542 -0.0001

TYR 542 SER 543 0.0000

SER 543 LEU 544 -0.0004

LEU 544 SER 545 0.0000

SER 545 THR 546 0.0000

THR 546 LEU 547 -0.0042

LEU 547 ASP 548 -0.0003

ASP 548 CYS 549 -0.0001

CYS 549 SER 550 -0.0000

SER 550 PHE 551 0.0001

PHE 551 ASN 552 -0.0001

ASN 552 ARG 553 0.0003

ARG 553 ILE 554 -0.0001

ILE 554 GLU 555 0.0063

GLU 555 THR 556 -0.0002

THR 556 SER 557 0.0005

SER 557 LYS 558 -0.0002

LYS 558 GLY 559 0.0003

GLY 559 ILE 560 -0.0003

ILE 560 LEU 561 -0.0000

LEU 561 GLN 562 0.0000

GLN 562 HIS 563 -0.0045

HIS 563 PHE 564 0.0002

PHE 564 PRO 565 -0.0002

PRO 565 LYS 566 0.0001

LYS 566 SER 567 -0.0000

SER 567 LEU 568 0.0000

LEU 568 ALA 569 -0.0002

ALA 569 PHE 570 -0.0005

PHE 570 PHE 571 -0.0040

PHE 571 ASN 572 -0.0002

ASN 572 LEU 573 0.0003

LEU 573 THR 574 0.0001

THR 574 ASN 575 -0.0002

ASN 575 ASN 576 0.0003

ASN 576 SER 577 -0.0001

SER 577 VAL 578 0.0002

VAL 578 ALA 579 0.0125

ALA 579 CYS 580 -0.0004

CYS 580 ILE 581 -0.0001

ILE 581 CYS 582 0.0002

CYS 582 GLU 583 0.0003

GLU 583 HIS 584 -0.0000

HIS 584 GLN 585 0.0001

GLN 585 LYS 586 -0.0002

LYS 586 PHE 587 0.0009

PHE 587 LEU 588 0.0003

LEU 588 GLN 589 0.0001

GLN 589 TRP 590 0.0001

TRP 590 VAL 591 -0.0002

VAL 591 LYS 592 -0.0000

LYS 592 GLU 593 0.0002

GLU 593 GLN 594 -0.0003

GLN 594 LYS 595 -0.0095

LYS 595 GLN 596 0.0002

GLN 596 PHE 597 -0.0003

PHE 597 LEU 598 -0.0001

LEU 598 VAL 599 0.0001

VAL 599 ASN 600 -0.0004

ASN 600 VAL 601 -0.0001

VAL 601 GLU 602 0.0001

GLU 602 GLN 603 -0.0029

GLN 603 MET 604 -0.0001

MET 604 THR 605 0.0002

THR 605 CYS 606 -0.0003

CYS 606 ALA 607 -0.0002

ALA 607 THR 608 0.0001

THR 608 PRO 609 0.0000

PRO 609 ASN 613 -0.0008

ASN 613 THR 614 -0.0001

THR 614 SER 615 -0.0004

SER 615 LEU 616 -0.0003

LEU 616 VAL 617 -0.0001

VAL 617 LEU 618 -0.0001

LEU 618 ASP 619 -0.0002

ASP 619 PHE 620 -0.0001

PHE 620 ASN 621 0.0034

ASN 621 ASN 622 -0.0001

ASN 622 SER 623 0.0004

SER 623 THR 624 -0.0000

THR 624 CYS 625 0.0001

CYS 625 GLN 21 0.0639

GLN 21 GLN 22 -0.0000

GLN 22 TRP 23 -0.0002

TRP 23 PHE 24 0.0002

PHE 24 CYS 25 -0.0001

CYS 25 ASN 26 -0.0003

ASN 26 SER 27 0.0001

SER 27 SER 28 -0.0001

SER 28 ASP 29 0.0026

ASP 29 ALA 30 0.0001

ALA 30 ILE 31 -0.0002

ILE 31 ILE 32 -0.0004

ILE 32 SER 33 0.0001

SER 33 TYR 34 0.0004

TYR 34 SER 35 -0.0002

SER 35 TYR 36 -0.0001

TYR 36 CYS 37 0.0014

CYS 37 ASP 38 -0.0002

ASP 38 HIS 39 -0.0003

HIS 39 LEU 40 -0.0002

LEU 40 LYS 41 0.0002

LYS 41 PHE 42 0.0003

PHE 42 PRO 43 0.0003

PRO 43 ILE 44 0.0002

ILE 44 SER 45 -0.0009

SER 45 ILE 46 -0.0000

ILE 46 SER 47 -0.0002

SER 47 SER 48 0.0002

SER 48 GLU 49 0.0003

GLU 49 PRO 50 0.0002

PRO 50 CYS 51 0.0001

CYS 51 ILE 52 -0.0000

ILE 52 ARG 53 -0.0036

ARG 53 LEU 54 0.0000

LEU 54 ARG 55 -0.0000

ARG 55 GLY 56 0.0002

GLY 56 THR 57 -0.0001

THR 57 ASN 58 -0.0000

ASN 58 GLY 59 -0.0000

GLY 59 PHE 60 0.0001

PHE 60 VAL 61 -0.0056

VAL 61 HIS 62 0.0002

HIS 62 VAL 63 0.0002

VAL 63 GLU 64 -0.0000

GLU 64 PHE 65 0.0000

PHE 65 ILE 66 0.0001

ILE 66 PRO 67 -0.0004

PRO 67 ARG 68 0.0001

ARG 68 GLY 69 0.0261

GLY 69 ASN 70 0.0000

ASN 70 LEU 71 0.0001

LEU 71 LYS 72 0.0000

LYS 72 TYR 73 0.0002

TYR 73 LEU 74 -0.0002

LEU 74 TYR 75 -0.0001

TYR 75 PHE 76 0.0004

PHE 76 ASN 77 -0.0148

ASN 77 LEU 78 0.0002

LEU 78 PHE 79 0.0002

PHE 79 ILE 80 0.0001

ILE 80 SER 81 0.0000

SER 81 VAL 82 0.0003

VAL 82 ASN 83 -0.0003

ASN 83 SER 84 0.0001

SER 84 ILE 85 0.0215

ILE 85 GLU 86 0.0001

GLU 86 LEU 87 -0.0001

LEU 87 PRO 88 -0.0001

PRO 88 LYS 89 0.0001

LYS 89 ARG 90 -0.0000

ARG 90 LYS 91 -0.0002

LYS 91 GLU 92 -0.0002

GLU 92 VAL 93 -0.0434

VAL 93 LEU 94 0.0004

LEU 94 CYS 95 0.0001

CYS 95 HIS 96 0.0001

HIS 96 GLY 97 -0.0000

GLY 97 HIS 98 -0.0001

HIS 98 ASP 99 0.0004

ASP 99 ASP 100 -0.0000

ASP 100 ASP 101 -0.0118

ASP 101 TYR 102 0.0001

TYR 102 SER 103 -0.0001

SER 103 PHE 104 0.0000

PHE 104 CYS 105 -0.0002

CYS 105 ARG 106 0.0000

ARG 106 ALA 107 0.0001

ALA 107 LEU 108 0.0001

LEU 108 LYS 109 0.0145

LYS 109 GLY 110 0.0000

GLY 110 GLU 111 0.0000

GLU 111 THR 112 0.0001

THR 112 VAL 113 -0.0002

VAL 113 ASN 114 0.0004

ASN 114 THR 115 -0.0007

THR 115 SER 116 0.0004

SER 116 ILE 117 0.0039

ILE 117 PRO 118 -0.0001

PRO 118 PHE 119 0.0001

PHE 119 SER 120 -0.0002

SER 120 PHE 121 -0.0003

PHE 121 GLU 122 0.0001

GLU 122 GLY 123 -0.0001

GLY 123 ILE 124 -0.0002

ILE 124 LEU 125 0.0117

LEU 125 PHE 126 -0.0000

PHE 126 PRO 127 0.0001

PRO 127 LYS 128 0.0000

LYS 128 GLY 129 0.0002

GLY 129 HIS 130 -0.0002

HIS 130 TYR 131 0.0001

TYR 131 ARG 132 0.0001

ARG 132 CYS 133 -0.0062

CYS 133 VAL 134 -0.0001

VAL 134 ALA 135 -0.0003

ALA 135 GLU 136 -0.0000

GLU 136 ALA 137 0.0004

ALA 137 ILE 138 -0.0003

ILE 138 ALA 139 0.0002

ALA 139 GLY 140 -0.0002

GLY 140 ASP 141 -0.0017

ASP 141 THR 142 -0.0003

THR 142 GLU 143 0.0001

GLU 143 GLU 144 -0.0003

GLU 144 LYS 145 0.0002

LYS 145 LEU 146 -0.0003

LEU 146 PHE 147 -0.0001

PHE 147 CYS 148 -0.0004

CYS 148 LEU 149 -0.0074

LEU 149 ASN 150 -0.0001

ASN 150 PHE 151 0.0001

PHE 151 THR 152 -0.0002

THR 152 ILE 153 -0.0004

ILE 153 ILE 154 -0.0001

ILE 154 HIS 155 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** TLR4/MD2/Jor ***

CA strain for 2403031259171421164

--- normal mode 10 ---

Should you encounter any unexpected behaviour,
please let us know.

* TLR4/MD2/Jor *