Should you encounter any unexpected behaviour,
please let us know.

* TLR4-MD2 complete *

CA strain for 240327122700959456

--- normal mode 8 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
GLU 27 PRO 28 0.0002

PRO 28 CYS 29 -0.0003

CYS 29 VAL 30 0.0000

VAL 30 GLU 31 0.0005

GLU 31 VAL 32 0.0001

VAL 32 VAL 33 -0.0001

VAL 33 PRO 34 0.0002

PRO 34 ASN 35 0.0001

ASN 35 ILE 36 0.0004

ILE 36 THR 37 -0.0001

THR 37 TYR 38 -0.0000

TYR 38 GLN 39 0.0001

GLN 39 CYS 40 -0.0001

CYS 40 MET 41 -0.0000

MET 41 GLU 42 -0.0002

GLU 42 LEU 43 -0.0033

LEU 43 ASN 44 0.0003

ASN 44 PHE 45 -0.0000

PHE 45 TYR 46 0.0002

TYR 46 LYS 47 0.0001

LYS 47 ILE 48 -0.0002

ILE 48 PRO 49 0.0005

PRO 49 ASP 50 -0.0000

ASP 50 ASN 51 0.0013

ASN 51 LEU 52 -0.0002

LEU 52 PRO 53 -0.0001

PRO 53 PHE 54 0.0000

PHE 54 SER 55 -0.0001

SER 55 THR 56 -0.0001

THR 56 LYS 57 0.0001

LYS 57 ASN 58 -0.0004

ASN 58 LEU 59 0.0026

LEU 59 ASP 60 -0.0004

ASP 60 LEU 61 0.0002

LEU 61 SER 62 0.0003

SER 62 PHE 63 0.0002

PHE 63 ASN 64 -0.0002

ASN 64 PRO 65 -0.0000

PRO 65 LEU 66 0.0000

LEU 66 ARG 67 -0.0022

ARG 67 HIS 68 -0.0002

HIS 68 LEU 69 0.0000

LEU 69 GLY 70 0.0000

GLY 70 SER 71 0.0000

SER 71 TYR 72 -0.0003

TYR 72 SER 73 0.0004

SER 73 PHE 74 0.0000

PHE 74 PHE 75 0.0037

PHE 75 SER 76 -0.0001

SER 76 PHE 77 0.0003

PHE 77 PRO 78 -0.0001

PRO 78 GLU 79 -0.0002

GLU 79 LEU 80 0.0002

LEU 80 GLN 81 -0.0004

GLN 81 VAL 82 0.0001

VAL 82 LEU 83 0.0039

LEU 83 ASP 84 0.0001

ASP 84 LEU 85 -0.0001

LEU 85 SER 86 0.0002

SER 86 ARG 87 -0.0001

ARG 87 CYS 88 0.0000

CYS 88 GLU 89 0.0000

GLU 89 ILE 90 -0.0002

ILE 90 GLN 91 -0.0049

GLN 91 THR 92 0.0003

THR 92 ILE 93 -0.0003

ILE 93 GLU 94 0.0002

GLU 94 ASP 95 -0.0004

ASP 95 GLY 96 0.0000

GLY 96 ALA 97 0.0000

ALA 97 TYR 98 -0.0001

TYR 98 GLN 99 0.0014

GLN 99 SER 100 -0.0003

SER 100 LEU 101 0.0001

LEU 101 SER 102 0.0003

SER 102 HIS 103 -0.0002

HIS 103 LEU 104 0.0001

LEU 104 SER 105 0.0002

SER 105 THR 106 0.0001

THR 106 LEU 107 0.0021

LEU 107 ILE 108 0.0003

ILE 108 LEU 109 0.0001

LEU 109 THR 110 0.0001

THR 110 GLY 111 -0.0001

GLY 111 ASN 112 -0.0002

ASN 112 PRO 113 0.0001

PRO 113 ILE 114 0.0002

ILE 114 GLN 115 -0.0030

GLN 115 SER 116 -0.0002

SER 116 LEU 117 -0.0003

LEU 117 ALA 118 0.0000

ALA 118 LEU 119 0.0005

LEU 119 GLY 120 -0.0001

GLY 120 ALA 121 0.0003

ALA 121 PHE 122 -0.0000

PHE 122 SER 123 0.0042

SER 123 GLY 124 -0.0000

GLY 124 LEU 125 0.0005

LEU 125 SER 126 -0.0001

SER 126 SER 127 -0.0002

SER 127 LEU 128 -0.0002

LEU 128 GLN 129 -0.0000

GLN 129 LYS 130 -0.0003

LYS 130 LEU 131 0.0035

LEU 131 VAL 132 0.0002

VAL 132 ALA 133 0.0001

ALA 133 VAL 134 -0.0001

VAL 134 GLU 135 0.0002

GLU 135 THR 136 -0.0001

THR 136 ASN 137 0.0003

ASN 137 LEU 138 0.0002

LEU 138 ALA 139 -0.0031

ALA 139 SER 140 -0.0002

SER 140 LEU 141 0.0000

LEU 141 GLU 142 -0.0001

GLU 142 ASN 143 0.0001

ASN 143 PHE 144 -0.0000

PHE 144 PRO 145 -0.0001

PRO 145 ILE 146 0.0001

ILE 146 GLY 147 -0.0045

GLY 147 HIS 148 -0.0001

HIS 148 LEU 149 -0.0002

LEU 149 LYS 150 -0.0001

LYS 150 THR 151 0.0003

THR 151 LEU 152 0.0001

LEU 152 LYS 153 0.0000

LYS 153 GLU 154 0.0003

GLU 154 LEU 155 0.0031

LEU 155 ASN 156 -0.0003

ASN 156 VAL 157 0.0005

VAL 157 ALA 158 0.0001

ALA 158 HIS 159 -0.0002

HIS 159 ASN 160 0.0002

ASN 160 LEU 161 0.0000

LEU 161 ILE 162 0.0001

ILE 162 GLN 163 0.0010

GLN 163 SER 164 -0.0001

SER 164 PHE 165 0.0003

PHE 165 LYS 166 0.0001

LYS 166 LEU 167 -0.0001

LEU 167 PRO 168 0.0001

PRO 168 GLU 169 0.0002

GLU 169 TYR 170 -0.0002

TYR 170 PHE 171 -0.0039

PHE 171 SER 172 -0.0002

SER 172 ASN 173 0.0001

ASN 173 LEU 174 -0.0002

LEU 174 THR 175 0.0002

THR 175 ASN 176 0.0002

ASN 176 LEU 177 -0.0003

LEU 177 GLU 178 -0.0003

GLU 178 HIS 179 0.0024

HIS 179 LEU 180 -0.0005

LEU 180 ASP 181 -0.0000

ASP 181 LEU 182 -0.0004

LEU 182 SER 183 -0.0001

SER 183 SER 184 -0.0002

SER 184 ASN 185 0.0001

ASN 185 LYS 186 0.0001

LYS 186 ILE 187 0.0008

ILE 187 GLN 188 0.0003

GLN 188 SER 189 -0.0002

SER 189 ILE 190 0.0003

ILE 190 TYR 191 0.0001

TYR 191 CYS 192 -0.0003

CYS 192 THR 193 0.0004

THR 193 ASP 194 0.0000

ASP 194 LEU 195 0.0012

LEU 195 ARG 196 0.0003

ARG 196 VAL 197 -0.0002

VAL 197 LEU 198 -0.0004

LEU 198 HIS 199 0.0004

HIS 199 GLN 200 0.0003

GLN 200 MET 201 -0.0002

MET 201 PRO 202 0.0002

PRO 202 LEU 203 0.0006

LEU 203 LEU 204 0.0005

LEU 204 ASN 205 0.0001

ASN 205 LEU 206 0.0001

LEU 206 SER 207 0.0000

SER 207 LEU 208 0.0001

LEU 208 ASP 209 0.0001

ASP 209 LEU 210 0.0000

LEU 210 SER 211 0.0057

SER 211 LEU 212 -0.0004

LEU 212 ASN 213 0.0003

ASN 213 PRO 214 -0.0004

PRO 214 MET 215 0.0003

MET 215 ASN 216 -0.0000

ASN 216 PHE 217 0.0001

PHE 217 ILE 218 0.0000

ILE 218 GLN 219 0.0007

GLN 219 PRO 220 0.0003

PRO 220 GLY 221 -0.0000

GLY 221 ALA 222 0.0004

ALA 222 PHE 223 -0.0001

PHE 223 LYS 224 0.0002

LYS 224 GLU 225 0.0001

GLU 225 ILE 226 0.0000

ILE 226 ARG 227 -0.0022

ARG 227 LEU 228 0.0002

LEU 228 HIS 229 -0.0005

HIS 229 LYS 230 -0.0001

LYS 230 LEU 231 -0.0000

LEU 231 THR 232 -0.0000

THR 232 LEU 233 0.0002

LEU 233 ARG 234 -0.0000

ARG 234 ASN 235 -0.0034

ASN 235 ASN 236 0.0002

ASN 236 PHE 237 0.0000

PHE 237 ASP 238 -0.0002

ASP 238 SER 239 -0.0001

SER 239 LEU 240 0.0001

LEU 240 ASN 241 -0.0000

ASN 241 VAL 242 -0.0002

VAL 242 MET 243 0.0018

MET 243 LYS 244 -0.0002

LYS 244 THR 245 0.0000

THR 245 CYS 246 0.0002

CYS 246 ILE 247 -0.0004

ILE 247 GLN 248 0.0000

GLN 248 GLY 249 0.0002

GLY 249 LEU 250 0.0001

LEU 250 ALA 251 0.0073

ALA 251 GLY 252 0.0000

GLY 252 LEU 253 0.0003

LEU 253 GLU 254 -0.0003

GLU 254 VAL 255 0.0000

VAL 255 HIS 256 -0.0001

HIS 256 ARG 257 0.0000

ARG 257 LEU 258 -0.0001

LEU 258 VAL 259 0.0000

VAL 259 LEU 260 0.0001

LEU 260 GLY 261 -0.0000

GLY 261 GLU 262 0.0002

GLU 262 PHE 263 -0.0001

PHE 263 ARG 264 0.0001

ARG 264 ASN 265 0.0003

ASN 265 GLU 266 -0.0001

GLU 266 GLY 267 0.0079

GLY 267 ASN 268 0.0001

ASN 268 LEU 269 0.0002

LEU 269 GLU 270 0.0000

GLU 270 LYS 271 -0.0001

LYS 271 PHE 272 -0.0000

PHE 272 ASP 273 0.0003

ASP 273 LYS 274 0.0001

LYS 274 SER 275 0.0097

SER 275 ALA 276 0.0003

ALA 276 LEU 277 0.0001

LEU 277 GLU 278 0.0001

GLU 278 GLY 279 0.0003

GLY 279 LEU 280 0.0002

LEU 280 CYS 281 0.0004

CYS 281 ASN 282 -0.0003

ASN 282 LEU 283 -0.0030

LEU 283 THR 284 -0.0001

THR 284 ILE 285 -0.0001

ILE 285 GLU 286 0.0001

GLU 286 GLU 287 0.0001

GLU 287 PHE 288 0.0000

PHE 288 ARG 289 -0.0005

ARG 289 LEU 290 0.0002

LEU 290 ALA 291 0.0022

ALA 291 TYR 292 -0.0001

TYR 292 LEU 293 0.0000

LEU 293 ASP 294 0.0001

ASP 294 TYR 295 0.0001

TYR 295 TYR 296 -0.0000

TYR 296 LEU 297 0.0001

LEU 297 ASP 298 -0.0000

ASP 298 ASP 299 0.0015

ASP 299 ILE 300 0.0001

ILE 300 ILE 301 -0.0004

ILE 301 ASP 302 -0.0000

ASP 302 LEU 303 -0.0000

LEU 303 PHE 304 0.0001

PHE 304 ASN 305 -0.0000

ASN 305 CYS 306 -0.0001

CYS 306 LEU 307 -0.0039

LEU 307 THR 308 0.0003

THR 308 ASN 309 0.0001

ASN 309 VAL 310 0.0002

VAL 310 SER 311 0.0003

SER 311 SER 312 -0.0000

SER 312 PHE 313 0.0002

PHE 313 SER 314 0.0001

SER 314 LEU 315 -0.0023

LEU 315 VAL 316 0.0000

VAL 316 SER 317 -0.0001

SER 317 VAL 318 0.0004

VAL 318 THR 319 -0.0004

THR 319 ILE 320 0.0005

ILE 320 GLU 321 -0.0000

GLU 321 ARG 322 0.0002

ARG 322 VAL 323 0.0079

VAL 323 LYS 324 -0.0001

LYS 324 ASP 325 -0.0000

ASP 325 PHE 326 -0.0000

PHE 326 SER 327 -0.0002

SER 327 TYR 328 -0.0003

TYR 328 ASN 329 0.0005

ASN 329 PHE 330 0.0003

PHE 330 GLY 331 -0.0026

GLY 331 TRP 332 0.0002

TRP 332 GLN 333 0.0001

GLN 333 HIS 334 -0.0002

HIS 334 LEU 335 0.0003

LEU 335 GLU 336 -0.0002

GLU 336 LEU 337 -0.0000

LEU 337 VAL 338 -0.0002

VAL 338 ASN 339 0.0131

ASN 339 CYS 340 0.0001

CYS 340 LYS 341 -0.0003

LYS 341 PHE 342 0.0001

PHE 342 GLY 343 0.0002

GLY 343 GLN 344 0.0000

GLN 344 PHE 345 0.0001

PHE 345 PRO 346 0.0001

PRO 346 THR 347 -0.0073

THR 347 LEU 348 0.0003

LEU 348 LYS 349 -0.0001

LYS 349 LEU 350 0.0001

LEU 350 LYS 351 0.0005

LYS 351 SER 352 -0.0001

SER 352 LEU 353 0.0003

LEU 353 LYS 354 -0.0000

LYS 354 ARG 355 0.0085

ARG 355 LEU 356 -0.0003

LEU 356 THR 357 -0.0000

THR 357 PHE 358 0.0003

PHE 358 THR 359 0.0003

THR 359 SER 360 -0.0002

SER 360 ASN 361 -0.0003

ASN 361 LYS 362 0.0001

LYS 362 GLY 363 0.0213

GLY 363 GLY 364 -0.0001

GLY 364 ASN 365 0.0002

ASN 365 ALA 366 -0.0002

ALA 366 PHE 367 0.0002

PHE 367 SER 368 0.0001

SER 368 GLU 369 0.0001

GLU 369 VAL 370 0.0002

VAL 370 ASP 371 -0.0081

ASP 371 LEU 372 -0.0006

LEU 372 PRO 373 0.0002

PRO 373 SER 374 -0.0000

SER 374 LEU 375 -0.0003

LEU 375 GLU 376 0.0001

GLU 376 PHE 377 0.0002

PHE 377 LEU 378 0.0000

LEU 378 ASP 379 0.0071

ASP 379 LEU 380 -0.0001

LEU 380 SER 381 0.0000

SER 381 ARG 382 0.0001

ARG 382 ASN 383 0.0000

ASN 383 GLY 384 -0.0002

GLY 384 LEU 385 0.0004

LEU 385 SER 386 -0.0002

SER 386 PHE 387 0.0038

PHE 387 LYS 388 0.0003

LYS 388 GLY 389 -0.0001

GLY 389 CYS 390 -0.0001

CYS 390 CYS 391 0.0000

CYS 391 SER 392 -0.0003

SER 392 GLN 393 0.0003

GLN 393 SER 394 0.0001

SER 394 ASP 395 -0.0034

ASP 395 PHE 396 -0.0001

PHE 396 GLY 397 0.0004

GLY 397 THR 398 -0.0002

THR 398 THR 399 0.0004

THR 399 SER 400 0.0000

SER 400 LEU 401 -0.0001

LEU 401 LYS 402 0.0001

LYS 402 TYR 403 0.0021

TYR 403 LEU 404 -0.0000

LEU 404 ASP 405 -0.0000

ASP 405 LEU 406 0.0003

LEU 406 SER 407 -0.0005

SER 407 PHE 408 0.0000

PHE 408 ASN 409 -0.0004

ASN 409 GLY 410 -0.0000

GLY 410 VAL 411 0.0073

VAL 411 ILE 412 -0.0002

ILE 412 THR 413 0.0003

THR 413 MET 414 0.0001

MET 414 SER 415 -0.0004

SER 415 SER 416 0.0002

SER 416 ASN 417 -0.0004

ASN 417 PHE 418 -0.0000

PHE 418 LEU 419 0.0151

LEU 419 GLY 420 0.0002

GLY 420 LEU 421 0.0001

LEU 421 GLU 422 0.0001

GLU 422 GLN 423 0.0001

GLN 423 LEU 424 -0.0004

LEU 424 GLU 425 0.0001

GLU 425 HIS 426 0.0001

HIS 426 LEU 427 0.0058

LEU 427 ASP 428 -0.0000

ASP 428 PHE 429 -0.0003

PHE 429 GLN 430 0.0004

GLN 430 HIS 431 0.0001

HIS 431 SER 432 -0.0002

SER 432 ASN 433 -0.0000

ASN 433 LEU 434 -0.0001

LEU 434 LYS 435 0.0100

LYS 435 GLN 436 -0.0003

GLN 436 MET 437 0.0001

MET 437 SER 438 -0.0002

SER 438 GLU 439 -0.0002

GLU 439 PHE 440 -0.0001

PHE 440 SER 441 0.0002

SER 441 VAL 442 -0.0004

VAL 442 PHE 443 0.0013

PHE 443 LEU 444 -0.0005

LEU 444 SER 445 -0.0002

SER 445 LEU 446 0.0002

LEU 446 ARG 447 0.0003

ARG 447 ASN 448 -0.0001

ASN 448 LEU 449 0.0002

LEU 449 ILE 450 -0.0001

ILE 450 TYR 451 -0.0022

TYR 451 LEU 452 0.0001

LEU 452 ASP 453 -0.0000

ASP 453 ILE 454 0.0001

ILE 454 SER 455 0.0004

SER 455 HIS 456 -0.0003

HIS 456 THR 457 -0.0001

THR 457 HIS 458 0.0003

HIS 458 THR 459 0.0113

THR 459 ARG 460 0.0001

ARG 460 VAL 461 -0.0002

VAL 461 ALA 462 -0.0002

ALA 462 PHE 463 0.0004

PHE 463 ASN 464 0.0001

ASN 464 GLY 465 -0.0001

GLY 465 ILE 466 0.0002

ILE 466 PHE 467 0.0053

PHE 467 ASN 468 -0.0000

ASN 468 GLY 469 0.0002

GLY 469 LEU 470 -0.0006

LEU 470 SER 471 -0.0002

SER 471 SER 472 0.0002

SER 472 LEU 473 0.0001

LEU 473 GLU 474 -0.0001

GLU 474 VAL 475 -0.0003

VAL 475 LEU 476 -0.0000

LEU 476 LYS 477 0.0003

LYS 477 MET 478 0.0001

MET 478 ALA 479 -0.0002

ALA 479 GLY 480 -0.0002

GLY 480 ASN 481 0.0001

ASN 481 SER 482 -0.0000

SER 482 PHE 483 -0.0062

PHE 483 GLN 484 0.0002

GLN 484 GLU 485 -0.0000

GLU 485 ASN 486 0.0000

ASN 486 PHE 487 -0.0002

PHE 487 LEU 488 -0.0002

LEU 488 PRO 489 0.0001

PRO 489 ASP 490 0.0002

ASP 490 ILE 491 0.0057

ILE 491 PHE 492 0.0002

PHE 492 THR 493 -0.0001

THR 493 GLU 494 0.0001

GLU 494 LEU 495 -0.0003

LEU 495 ARG 496 -0.0000

ARG 496 ASN 497 -0.0000

ASN 497 LEU 498 -0.0004

LEU 498 THR 499 0.0009

THR 499 PHE 500 0.0000

PHE 500 LEU 501 -0.0000

LEU 501 ASP 502 0.0001

ASP 502 LEU 503 0.0002

LEU 503 SER 504 0.0002

SER 504 GLN 505 -0.0000

GLN 505 CYS 506 0.0003

CYS 506 GLN 507 0.0033

GLN 507 LEU 508 -0.0004

LEU 508 GLU 509 0.0002

GLU 509 GLN 510 0.0001

GLN 510 LEU 511 -0.0003

LEU 511 SER 512 0.0001

SER 512 PRO 513 0.0001

PRO 513 THR 514 0.0000

THR 514 ALA 515 -0.0021

ALA 515 PHE 516 0.0005

PHE 516 ASN 517 -0.0001

ASN 517 SER 518 0.0001

SER 518 LEU 519 -0.0002

LEU 519 SER 520 -0.0004

SER 520 SER 521 0.0004

SER 521 LEU 522 -0.0003

LEU 522 GLN 523 0.0010

GLN 523 VAL 524 0.0000

VAL 524 LEU 525 0.0001

LEU 525 ASN 526 -0.0000

ASN 526 MET 527 -0.0003

MET 527 SER 528 0.0001

SER 528 HIS 529 0.0001

HIS 529 ASN 530 0.0000

ASN 530 ASN 531 0.0000

ASN 531 PHE 532 -0.0000

PHE 532 PHE 533 0.0000

PHE 533 SER 534 0.0001

SER 534 LEU 535 0.0001

LEU 535 ASP 536 -0.0000

ASP 536 THR 537 -0.0000

THR 537 PHE 538 -0.0002

PHE 538 PRO 539 0.0053

PRO 539 TYR 540 0.0000

TYR 540 LYS 541 0.0003

LYS 541 CYS 542 0.0002

CYS 542 LEU 543 -0.0001

LEU 543 ASN 544 -0.0000

ASN 544 SER 545 0.0001

SER 545 LEU 546 0.0001

LEU 546 GLN 547 0.0021

GLN 547 VAL 548 -0.0000

VAL 548 LEU 549 -0.0002

LEU 549 ASP 550 0.0001

ASP 550 TYR 551 0.0001

TYR 551 SER 552 -0.0002

SER 552 LEU 553 0.0005

LEU 553 ASN 554 -0.0001

ASN 554 HIS 555 -0.0036

HIS 555 ILE 556 -0.0002

ILE 556 MET 557 -0.0001

MET 557 THR 558 -0.0001

THR 558 SER 559 0.0001

SER 559 LYS 560 0.0000

LYS 560 LYS 561 -0.0001

LYS 561 GLN 562 -0.0000

GLN 562 GLU 563 -0.0005

GLU 563 LEU 564 0.0003

LEU 564 GLN 565 -0.0001

GLN 565 HIS 566 -0.0003

HIS 566 PHE 567 0.0000

PHE 567 PRO 568 -0.0001

PRO 568 SER 569 -0.0001

SER 569 SER 570 0.0000

SER 570 LEU 571 0.0020

LEU 571 ALA 572 -0.0001

ALA 572 PHE 573 0.0001

PHE 573 LEU 574 0.0004

LEU 574 ASN 575 -0.0001

ASN 575 LEU 576 0.0000

LEU 576 THR 577 0.0003

THR 577 GLN 578 0.0001

GLN 578 ASN 579 0.0009

ASN 579 ASP 580 0.0000

ASP 580 PHE 581 0.0003

PHE 581 ALA 582 -0.0000

ALA 582 CYS 583 -0.0004

CYS 583 THR 584 -0.0001

THR 584 CYS 585 0.0002

CYS 585 GLU 586 -0.0004

GLU 586 HIS 587 0.0011

HIS 587 GLN 588 0.0003

GLN 588 SER 589 0.0002

SER 589 PHE 590 -0.0003

PHE 590 LEU 591 0.0000

LEU 591 GLN 592 0.0001

GLN 592 TRP 593 -0.0001

TRP 593 ILE 594 -0.0003

ILE 594 LYS 595 0.0036

LYS 595 ASP 596 -0.0000

ASP 596 GLN 597 -0.0005

GLN 597 ARG 598 0.0001

ARG 598 GLN 599 -0.0002

GLN 599 LEU 600 0.0004

LEU 600 LEU 601 -0.0000

LEU 601 VAL 602 0.0002

VAL 602 GLU 603 0.0006

GLU 603 VAL 604 -0.0000

VAL 604 GLU 605 0.0004

GLU 605 ARG 606 0.0003

ARG 606 MET 607 -0.0001

MET 607 GLU 608 -0.0003

GLU 608 CYS 609 -0.0003

CYS 609 ALA 610 0.0005

ALA 610 THR 611 -0.0008

THR 611 PRO 612 0.0002

PRO 612 SER 613 0.0000

SER 613 ASP 614 0.0002

ASP 614 LYS 615 0.0002

LYS 615 GLN 616 0.0001

GLN 616 GLY 617 -0.0001

GLY 617 MET 618 -0.0002

MET 618 PRO 619 0.0003

PRO 619 VAL 620 -0.0001

VAL 620 LEU 621 0.0004

LEU 621 SER 622 0.0002

SER 622 LEU 623 0.0001

LEU 623 ASN 624 -0.0001

ASN 624 ILE 625 0.0002

ILE 625 THR 626 -0.0003

THR 626 CYS 627 -0.0017

CYS 627 GLU 27 0.0572

GLU 27 PRO 28 0.0001

PRO 28 CYS 29 -0.0002

CYS 29 VAL 30 0.0001

VAL 30 GLU 31 -0.0002

GLU 31 VAL 32 0.0003

VAL 32 VAL 33 0.0000

VAL 33 PRO 34 -0.0001

PRO 34 ASN 35 -0.0001

ASN 35 ILE 36 0.0000

ILE 36 THR 37 -0.0000

THR 37 TYR 38 0.0001

TYR 38 GLN 39 -0.0000

GLN 39 CYS 40 -0.0003

CYS 40 MET 41 0.0000

MET 41 GLU 42 0.0000

GLU 42 LEU 43 0.0032

LEU 43 ASN 44 0.0002

ASN 44 PHE 45 -0.0000

PHE 45 TYR 46 0.0002

TYR 46 LYS 47 0.0005

LYS 47 ILE 48 -0.0004

ILE 48 PRO 49 -0.0002

PRO 49 ASP 50 0.0001

ASP 50 ASN 51 -0.0014

ASN 51 LEU 52 0.0000

LEU 52 PRO 53 0.0002

PRO 53 PHE 54 -0.0002

PHE 54 SER 55 -0.0001

SER 55 THR 56 0.0001

THR 56 LYS 57 -0.0001

LYS 57 ASN 58 0.0004

ASN 58 LEU 59 -0.0020

LEU 59 ASP 60 0.0001

ASP 60 LEU 61 -0.0002

LEU 61 SER 62 -0.0000

SER 62 PHE 63 -0.0001

PHE 63 ASN 64 0.0000

ASN 64 PRO 65 -0.0003

PRO 65 LEU 66 0.0001

LEU 66 ARG 67 0.0024

ARG 67 HIS 68 0.0001

HIS 68 LEU 69 0.0001

LEU 69 GLY 70 -0.0002

GLY 70 SER 71 0.0004

SER 71 TYR 72 -0.0000

TYR 72 SER 73 -0.0000

SER 73 PHE 74 -0.0001

PHE 74 PHE 75 -0.0036

PHE 75 SER 76 -0.0001

SER 76 PHE 77 -0.0002

PHE 77 PRO 78 -0.0003

PRO 78 GLU 79 0.0001

GLU 79 LEU 80 -0.0002

LEU 80 GLN 81 0.0001

GLN 81 VAL 82 0.0001

VAL 82 LEU 83 -0.0042

LEU 83 ASP 84 -0.0001

ASP 84 LEU 85 0.0000

LEU 85 SER 86 -0.0002

SER 86 ARG 87 -0.0001

ARG 87 CYS 88 -0.0004

CYS 88 GLU 89 0.0002

GLU 89 ILE 90 -0.0000

ILE 90 GLN 91 0.0053

GLN 91 THR 92 0.0003

THR 92 ILE 93 0.0000

ILE 93 GLU 94 0.0005

GLU 94 ASP 95 -0.0002

ASP 95 GLY 96 0.0003

GLY 96 ALA 97 -0.0003

ALA 97 TYR 98 -0.0003

TYR 98 GLN 99 -0.0017

GLN 99 SER 100 -0.0002

SER 100 LEU 101 -0.0002

LEU 101 SER 102 0.0000

SER 102 HIS 103 -0.0001

HIS 103 LEU 104 -0.0002

LEU 104 SER 105 0.0003

SER 105 THR 106 -0.0002

THR 106 LEU 107 -0.0015

LEU 107 ILE 108 -0.0002

ILE 108 LEU 109 -0.0001

LEU 109 THR 110 0.0001

THR 110 GLY 111 -0.0000

GLY 111 ASN 112 0.0003

ASN 112 PRO 113 -0.0001

PRO 113 ILE 114 -0.0001

ILE 114 GLN 115 0.0028

GLN 115 SER 116 -0.0002

SER 116 LEU 117 0.0003

LEU 117 ALA 118 -0.0004

ALA 118 LEU 119 -0.0002

LEU 119 GLY 120 0.0002

GLY 120 ALA 121 -0.0006

ALA 121 PHE 122 0.0001

PHE 122 SER 123 -0.0034

SER 123 GLY 124 -0.0000

GLY 124 LEU 125 -0.0001

LEU 125 SER 126 0.0000

SER 126 SER 127 0.0002

SER 127 LEU 128 -0.0003

LEU 128 GLN 129 -0.0001

GLN 129 LYS 130 0.0002

LYS 130 LEU 131 -0.0032

LEU 131 VAL 132 0.0001

VAL 132 ALA 133 0.0001

ALA 133 VAL 134 -0.0001

VAL 134 GLU 135 -0.0003

GLU 135 THR 136 -0.0001

THR 136 ASN 137 -0.0002

ASN 137 LEU 138 0.0002

LEU 138 ALA 139 0.0033

ALA 139 SER 140 0.0001

SER 140 LEU 141 -0.0001

LEU 141 GLU 142 -0.0000

GLU 142 ASN 143 -0.0001

ASN 143 PHE 144 -0.0002

PHE 144 PRO 145 -0.0000

PRO 145 ILE 146 -0.0003

ILE 146 GLY 147 0.0041

GLY 147 HIS 148 -0.0001

HIS 148 LEU 149 0.0005

LEU 149 LYS 150 0.0000

LYS 150 THR 151 -0.0002

THR 151 LEU 152 -0.0001

LEU 152 LYS 153 0.0001

LYS 153 GLU 154 -0.0001

GLU 154 LEU 155 -0.0030

LEU 155 ASN 156 0.0000

ASN 156 VAL 157 -0.0001

VAL 157 ALA 158 0.0004

ALA 158 HIS 159 -0.0003

HIS 159 ASN 160 0.0004

ASN 160 LEU 161 -0.0000

LEU 161 ILE 162 -0.0004

ILE 162 GLN 163 -0.0006

GLN 163 SER 164 -0.0001

SER 164 PHE 165 0.0004

PHE 165 LYS 166 0.0000

LYS 166 LEU 167 0.0003

LEU 167 PRO 168 -0.0002

PRO 168 GLU 169 -0.0000

GLU 169 TYR 170 -0.0001

TYR 170 PHE 171 0.0038

PHE 171 SER 172 -0.0002

SER 172 ASN 173 -0.0001

ASN 173 LEU 174 -0.0002

LEU 174 THR 175 0.0002

THR 175 ASN 176 0.0001

ASN 176 LEU 177 -0.0004

LEU 177 GLU 178 -0.0001

GLU 178 HIS 179 -0.0026

HIS 179 LEU 180 0.0002

LEU 180 ASP 181 -0.0003

ASP 181 LEU 182 0.0003

LEU 182 SER 183 0.0002

SER 183 SER 184 -0.0004

SER 184 ASN 185 0.0000

ASN 185 LYS 186 0.0003

LYS 186 ILE 187 -0.0009

ILE 187 GLN 188 -0.0003

GLN 188 SER 189 0.0002

SER 189 ILE 190 0.0001

ILE 190 TYR 191 -0.0003

TYR 191 CYS 192 -0.0003

CYS 192 THR 193 -0.0000

THR 193 ASP 194 0.0001

ASP 194 LEU 195 -0.0012

LEU 195 ARG 196 0.0002

ARG 196 VAL 197 0.0001

VAL 197 LEU 198 0.0001

LEU 198 HIS 199 0.0002

HIS 199 GLN 200 -0.0001

GLN 200 MET 201 0.0002

MET 201 PRO 202 -0.0002

PRO 202 LEU 203 -0.0012

LEU 203 LEU 204 -0.0002

LEU 204 ASN 205 0.0002

ASN 205 LEU 206 -0.0003

LEU 206 SER 207 0.0002

SER 207 LEU 208 0.0002

LEU 208 ASP 209 -0.0002

ASP 209 LEU 210 0.0005

LEU 210 SER 211 -0.0059

SER 211 LEU 212 -0.0000

LEU 212 ASN 213 -0.0003

ASN 213 PRO 214 -0.0000

PRO 214 MET 215 0.0002

MET 215 ASN 216 0.0001

ASN 216 PHE 217 -0.0001

PHE 217 ILE 218 0.0002

ILE 218 GLN 219 -0.0002

GLN 219 PRO 220 0.0002

PRO 220 GLY 221 -0.0001

GLY 221 ALA 222 0.0001

ALA 222 PHE 223 -0.0001

PHE 223 LYS 224 0.0003

LYS 224 GLU 225 -0.0002

GLU 225 ILE 226 -0.0003

ILE 226 ARG 227 0.0022

ARG 227 LEU 228 -0.0002

LEU 228 HIS 229 0.0000

HIS 229 LYS 230 0.0002

LYS 230 LEU 231 -0.0001

LEU 231 THR 232 0.0001

THR 232 LEU 233 0.0001

LEU 233 ARG 234 0.0002

ARG 234 ASN 235 0.0032

ASN 235 ASN 236 -0.0000

ASN 236 PHE 237 -0.0002

PHE 237 ASP 238 -0.0001

ASP 238 SER 239 -0.0004

SER 239 LEU 240 0.0000

LEU 240 ASN 241 -0.0001

ASN 241 VAL 242 0.0001

VAL 242 MET 243 -0.0020

MET 243 LYS 244 0.0000

LYS 244 THR 245 0.0001

THR 245 CYS 246 0.0001

CYS 246 ILE 247 0.0000

ILE 247 GLN 248 -0.0002

GLN 248 GLY 249 -0.0003

GLY 249 LEU 250 -0.0001

LEU 250 ALA 251 -0.0070

ALA 251 GLY 252 -0.0003

GLY 252 LEU 253 -0.0001

LEU 253 GLU 254 0.0001

GLU 254 VAL 255 0.0001

VAL 255 HIS 256 -0.0002

HIS 256 ARG 257 -0.0001

ARG 257 LEU 258 0.0004

LEU 258 VAL 259 -0.0004

VAL 259 LEU 260 0.0003

LEU 260 GLY 261 -0.0004

GLY 261 GLU 262 -0.0001

GLU 262 PHE 263 0.0002

PHE 263 ARG 264 0.0001

ARG 264 ASN 265 -0.0004

ASN 265 GLU 266 0.0002

GLU 266 GLY 267 -0.0077

GLY 267 ASN 268 -0.0002

ASN 268 LEU 269 0.0002

LEU 269 GLU 270 0.0001

GLU 270 LYS 271 0.0001

LYS 271 PHE 272 0.0002

PHE 272 ASP 273 -0.0002

ASP 273 LYS 274 0.0002

LYS 274 SER 275 -0.0091

SER 275 ALA 276 -0.0002

ALA 276 LEU 277 -0.0001

LEU 277 GLU 278 0.0002

GLU 278 GLY 279 0.0003

GLY 279 LEU 280 -0.0003

LEU 280 CYS 281 0.0002

CYS 281 ASN 282 0.0001

ASN 282 LEU 283 0.0033

LEU 283 THR 284 0.0002

THR 284 ILE 285 -0.0003

ILE 285 GLU 286 -0.0000

GLU 286 GLU 287 -0.0002

GLU 287 PHE 288 -0.0001

PHE 288 ARG 289 -0.0001

ARG 289 LEU 290 0.0004

LEU 290 ALA 291 -0.0018

ALA 291 TYR 292 0.0001

TYR 292 LEU 293 -0.0002

LEU 293 ASP 294 0.0004

ASP 294 TYR 295 -0.0001

TYR 295 TYR 296 0.0003

TYR 296 LEU 297 0.0001

LEU 297 ASP 298 -0.0001

ASP 298 ASP 299 -0.0015

ASP 299 ILE 300 -0.0000

ILE 300 ILE 301 0.0002

ILE 301 ASP 302 -0.0002

ASP 302 LEU 303 0.0004

LEU 303 PHE 304 0.0003

PHE 304 ASN 305 -0.0001

ASN 305 CYS 306 0.0000

CYS 306 LEU 307 0.0036

LEU 307 THR 308 0.0000

THR 308 ASN 309 0.0001

ASN 309 VAL 310 -0.0003

VAL 310 SER 311 0.0002

SER 311 SER 312 -0.0001

SER 312 PHE 313 0.0001

PHE 313 SER 314 0.0000

SER 314 LEU 315 0.0023

LEU 315 VAL 316 -0.0002

VAL 316 SER 317 -0.0002

SER 317 VAL 318 -0.0002

VAL 318 THR 319 0.0002

THR 319 ILE 320 -0.0001

ILE 320 GLU 321 -0.0000

GLU 321 ARG 322 0.0002

ARG 322 VAL 323 -0.0083

VAL 323 LYS 324 -0.0001

LYS 324 ASP 325 -0.0004

ASP 325 PHE 326 -0.0004

PHE 326 SER 327 -0.0001

SER 327 TYR 328 0.0001

TYR 328 ASN 329 -0.0001

ASN 329 PHE 330 0.0002

PHE 330 GLY 331 0.0025

GLY 331 TRP 332 0.0002

TRP 332 GLN 333 -0.0005

GLN 333 HIS 334 -0.0001

HIS 334 LEU 335 0.0003

LEU 335 GLU 336 -0.0001

GLU 336 LEU 337 -0.0000

LEU 337 VAL 338 -0.0000

VAL 338 ASN 339 -0.0129

ASN 339 CYS 340 -0.0003

CYS 340 LYS 341 -0.0002

LYS 341 PHE 342 -0.0001

PHE 342 GLY 343 -0.0004

GLY 343 GLN 344 0.0003

GLN 344 PHE 345 -0.0002

PHE 345 PRO 346 -0.0002

PRO 346 THR 347 0.0073

THR 347 LEU 348 0.0004

LEU 348 LYS 349 -0.0005

LYS 349 LEU 350 0.0001

LEU 350 LYS 351 -0.0000

LYS 351 SER 352 -0.0002

SER 352 LEU 353 -0.0001

LEU 353 LYS 354 0.0003

LYS 354 ARG 355 -0.0078

ARG 355 LEU 356 0.0001

LEU 356 THR 357 -0.0001

THR 357 PHE 358 -0.0000

PHE 358 THR 359 -0.0002

THR 359 SER 360 -0.0000

SER 360 ASN 361 -0.0003

ASN 361 LYS 362 0.0002

LYS 362 GLY 363 -0.0210

GLY 363 GLY 364 -0.0003

GLY 364 ASN 365 -0.0000

ASN 365 ALA 366 -0.0003

ALA 366 PHE 367 0.0002

PHE 367 SER 368 0.0003

SER 368 GLU 369 -0.0003

GLU 369 VAL 370 0.0000

VAL 370 ASP 371 0.0084

ASP 371 LEU 372 -0.0001

LEU 372 PRO 373 0.0002

PRO 373 SER 374 -0.0001

SER 374 LEU 375 -0.0003

LEU 375 GLU 376 0.0004

GLU 376 PHE 377 0.0002

PHE 377 LEU 378 -0.0000

LEU 378 ASP 379 -0.0065

ASP 379 LEU 380 0.0001

LEU 380 SER 381 0.0000

SER 381 ARG 382 -0.0001

ARG 382 ASN 383 0.0000

ASN 383 GLY 384 0.0000

GLY 384 LEU 385 0.0002

LEU 385 SER 386 -0.0002

SER 386 PHE 387 -0.0040

PHE 387 LYS 388 -0.0001

LYS 388 GLY 389 -0.0002

GLY 389 CYS 390 0.0002

CYS 390 CYS 391 0.0001

CYS 391 SER 392 -0.0002

SER 392 GLN 393 0.0002

GLN 393 SER 394 0.0001

SER 394 ASP 395 0.0034

ASP 395 PHE 396 0.0000

PHE 396 GLY 397 -0.0002

GLY 397 THR 398 -0.0002

THR 398 THR 399 -0.0001

THR 399 SER 400 -0.0000

SER 400 LEU 401 -0.0002

LEU 401 LYS 402 -0.0004

LYS 402 TYR 403 -0.0016

TYR 403 LEU 404 -0.0001

LEU 404 ASP 405 0.0000

ASP 405 LEU 406 0.0001

LEU 406 SER 407 -0.0001

SER 407 PHE 408 -0.0001

PHE 408 ASN 409 0.0001

ASN 409 GLY 410 0.0000

GLY 410 VAL 411 -0.0073

VAL 411 ILE 412 0.0002

ILE 412 THR 413 -0.0000

THR 413 MET 414 0.0004

MET 414 SER 415 0.0001

SER 415 SER 416 0.0000

SER 416 ASN 417 0.0000

ASN 417 PHE 418 0.0001

PHE 418 LEU 419 -0.0147

LEU 419 GLY 420 0.0001

GLY 420 LEU 421 -0.0004

LEU 421 GLU 422 0.0001

GLU 422 GLN 423 -0.0001

GLN 423 LEU 424 0.0005

LEU 424 GLU 425 -0.0001

GLU 425 HIS 426 -0.0001

HIS 426 LEU 427 -0.0058

LEU 427 ASP 428 -0.0000

ASP 428 PHE 429 -0.0003

PHE 429 GLN 430 -0.0000

GLN 430 HIS 431 0.0002

HIS 431 SER 432 -0.0000

SER 432 ASN 433 -0.0001

ASN 433 LEU 434 0.0000

LEU 434 LYS 435 -0.0096

LYS 435 GLN 436 0.0001

GLN 436 MET 437 -0.0002

MET 437 SER 438 0.0001

SER 438 GLU 439 -0.0000

GLU 439 PHE 440 0.0004

PHE 440 SER 441 -0.0004

SER 441 VAL 442 -0.0002

VAL 442 PHE 443 -0.0015

PHE 443 LEU 444 -0.0000

LEU 444 SER 445 0.0000

SER 445 LEU 446 -0.0001

LEU 446 ARG 447 -0.0001

ARG 447 ASN 448 0.0004

ASN 448 LEU 449 0.0002

LEU 449 ILE 450 -0.0003

ILE 450 TYR 451 0.0023

TYR 451 LEU 452 -0.0002

LEU 452 ASP 453 0.0002

ASP 453 ILE 454 -0.0003

ILE 454 SER 455 -0.0002

SER 455 HIS 456 0.0002

HIS 456 THR 457 -0.0001

THR 457 HIS 458 0.0001

HIS 458 THR 459 -0.0112

THR 459 ARG 460 -0.0003

ARG 460 VAL 461 0.0001

VAL 461 ALA 462 0.0000

ALA 462 PHE 463 0.0001

PHE 463 ASN 464 -0.0002

ASN 464 GLY 465 0.0002

GLY 465 ILE 466 -0.0002

ILE 466 PHE 467 -0.0063

PHE 467 ASN 468 0.0003

ASN 468 GLY 469 -0.0003

GLY 469 LEU 470 0.0001

LEU 470 SER 471 0.0001

SER 471 SER 472 -0.0001

SER 472 LEU 473 0.0003

LEU 473 GLU 474 -0.0004

GLU 474 VAL 475 0.0003

VAL 475 LEU 476 0.0003

LEU 476 LYS 477 -0.0002

LYS 477 MET 478 0.0001

MET 478 ALA 479 0.0002

ALA 479 GLY 480 -0.0001

GLY 480 ASN 481 -0.0000

ASN 481 SER 482 -0.0004

SER 482 PHE 483 0.0060

PHE 483 GLN 484 -0.0001

GLN 484 GLU 485 0.0002

GLU 485 ASN 486 0.0000

ASN 486 PHE 487 -0.0004

PHE 487 LEU 488 0.0004

LEU 488 PRO 489 -0.0004

PRO 489 ASP 490 0.0004

ASP 490 ILE 491 -0.0054

ILE 491 PHE 492 -0.0000

PHE 492 THR 493 0.0000

THR 493 GLU 494 0.0001

GLU 494 LEU 495 -0.0001

LEU 495 ARG 496 -0.0001

ARG 496 ASN 497 0.0002

ASN 497 LEU 498 0.0002

LEU 498 THR 499 -0.0011

THR 499 PHE 500 -0.0000

PHE 500 LEU 501 0.0002

LEU 501 ASP 502 -0.0002

ASP 502 LEU 503 -0.0004

LEU 503 SER 504 0.0002

SER 504 GLN 505 0.0002

GLN 505 CYS 506 0.0002

CYS 506 GLN 507 -0.0034

GLN 507 LEU 508 0.0001

LEU 508 GLU 509 -0.0004

GLU 509 GLN 510 0.0001

GLN 510 LEU 511 0.0002

LEU 511 SER 512 -0.0000

SER 512 PRO 513 0.0001

PRO 513 THR 514 0.0001

THR 514 ALA 515 0.0017

ALA 515 PHE 516 -0.0000

PHE 516 ASN 517 0.0002

ASN 517 SER 518 0.0002

SER 518 LEU 519 -0.0000

LEU 519 SER 520 0.0001

SER 520 SER 521 0.0003

SER 521 LEU 522 0.0002

LEU 522 GLN 523 -0.0008

GLN 523 VAL 524 0.0000

VAL 524 LEU 525 -0.0001

LEU 525 ASN 526 0.0001

ASN 526 MET 527 -0.0002

MET 527 SER 528 0.0001

SER 528 HIS 529 0.0001

HIS 529 ASN 530 -0.0003

ASN 530 ASN 531 -0.0000

ASN 531 PHE 532 -0.0004

PHE 532 PHE 533 0.0003

PHE 533 SER 534 -0.0001

SER 534 LEU 535 -0.0001

LEU 535 ASP 536 0.0001

ASP 536 THR 537 -0.0002

THR 537 PHE 538 0.0001

PHE 538 PRO 539 -0.0053

PRO 539 TYR 540 0.0001

TYR 540 LYS 541 0.0004

LYS 541 CYS 542 -0.0001

CYS 542 LEU 543 0.0000

LEU 543 ASN 544 0.0003

ASN 544 SER 545 -0.0002

SER 545 LEU 546 -0.0002

LEU 546 GLN 547 -0.0022

GLN 547 VAL 548 0.0001

VAL 548 LEU 549 -0.0002

LEU 549 ASP 550 0.0001

ASP 550 TYR 551 0.0002

TYR 551 SER 552 0.0002

SER 552 LEU 553 -0.0000

LEU 553 ASN 554 -0.0001

ASN 554 HIS 555 0.0031

HIS 555 ILE 556 0.0002

ILE 556 MET 557 -0.0001

MET 557 THR 558 0.0001

THR 558 SER 559 0.0000

SER 559 LYS 560 -0.0005

LYS 560 LYS 561 0.0004

LYS 561 GLN 562 0.0001

GLN 562 GLU 563 0.0006

GLU 563 LEU 564 -0.0001

LEU 564 GLN 565 -0.0002

GLN 565 HIS 566 -0.0001

HIS 566 PHE 567 0.0001

PHE 567 PRO 568 -0.0002

PRO 568 SER 569 0.0001

SER 569 SER 570 -0.0000

SER 570 LEU 571 -0.0021

LEU 571 ALA 572 0.0001

ALA 572 PHE 573 -0.0001

PHE 573 LEU 574 -0.0001

LEU 574 ASN 575 0.0001

ASN 575 LEU 576 -0.0002

LEU 576 THR 577 0.0003

THR 577 GLN 578 -0.0004

GLN 578 ASN 579 -0.0007

ASN 579 ASP 580 -0.0001

ASP 580 PHE 581 -0.0001

PHE 581 ALA 582 0.0001

ALA 582 CYS 583 -0.0003

CYS 583 THR 584 0.0004

THR 584 CYS 585 0.0000

CYS 585 GLU 586 0.0003

GLU 586 HIS 587 -0.0014

HIS 587 GLN 588 -0.0003

GLN 588 SER 589 0.0000

SER 589 PHE 590 0.0005

PHE 590 LEU 591 -0.0001

LEU 591 GLN 592 0.0000

GLN 592 TRP 593 0.0001

TRP 593 ILE 594 0.0004

ILE 594 LYS 595 -0.0037

LYS 595 ASP 596 0.0001

ASP 596 GLN 597 0.0001

GLN 597 ARG 598 -0.0003

ARG 598 GLN 599 -0.0005

GLN 599 LEU 600 -0.0002

LEU 600 LEU 601 -0.0000

LEU 601 VAL 602 -0.0000

VAL 602 GLU 603 -0.0003

GLU 603 VAL 604 -0.0002

VAL 604 GLU 605 0.0001

GLU 605 ARG 606 0.0001

ARG 606 MET 607 0.0003

MET 607 GLU 608 -0.0000

GLU 608 CYS 609 -0.0002

CYS 609 ALA 610 -0.0002

ALA 610 THR 611 0.0004

THR 611 PRO 612 -0.0003

PRO 612 SER 613 0.0001

SER 613 ASP 614 0.0001

ASP 614 LYS 615 -0.0004

LYS 615 GLN 616 0.0001

GLN 616 GLY 617 0.0001

GLY 617 MET 618 -0.0001

MET 618 PRO 619 -0.0003

PRO 619 VAL 620 0.0002

VAL 620 LEU 621 -0.0005

LEU 621 SER 622 -0.0001

SER 622 LEU 623 -0.0001

LEU 623 ASN 624 0.0002

ASN 624 ILE 625 -0.0002

ILE 625 THR 626 0.0001

THR 626 CYS 627 0.0017

CYS 627 GLN 19 -0.0366

GLN 19 LYS 20 -0.0002

LYS 20 GLN 21 -0.0004

GLN 21 TYR 22 0.0001

TYR 22 TRP 23 0.0004

TRP 23 VAL 24 -0.0003

VAL 24 CYS 25 -0.0000

CYS 25 ASN 26 -0.0001

ASN 26 SER 27 0.0093

SER 27 SER 28 0.0002

SER 28 ASP 29 -0.0002

ASP 29 ALA 30 -0.0001

ALA 30 SER 31 -0.0001

SER 31 ILE 32 -0.0002

ILE 32 SER 33 -0.0001

SER 33 TYR 34 -0.0002

TYR 34 THR 35 0.0033

THR 35 TYR 36 0.0000

TYR 36 CYS 37 -0.0000

CYS 37 ASP 38 -0.0001

ASP 38 LYS 39 0.0001

LYS 39 MET 40 -0.0002

MET 40 GLN 41 -0.0001

GLN 41 TYR 42 -0.0003

TYR 42 PRO 43 0.0060

PRO 43 ILE 44 -0.0003

ILE 44 SER 45 -0.0002

SER 45 ILE 46 0.0001

ILE 46 ASN 47 0.0002

ASN 47 VAL 48 -0.0000

VAL 48 ASN 49 0.0003

ASN 49 PRO 50 -0.0003

PRO 50 CYS 51 -0.0053

CYS 51 ILE 52 0.0000

ILE 52 GLU 53 0.0001

GLU 53 LEU 54 -0.0000

LEU 54 LYS 55 0.0003

LYS 55 GLY 56 -0.0002

GLY 56 SER 57 -0.0002

SER 57 LYS 58 0.0002

LYS 58 GLY 59 0.0169

GLY 59 LEU 60 0.0004

LEU 60 LEU 61 0.0000

LEU 61 HIS 62 0.0002

HIS 62 ILE 63 0.0001

ILE 63 PHE 64 -0.0000

PHE 64 TYR 65 0.0001

TYR 65 ILE 66 0.0001

ILE 66 PRO 67 0.0036

PRO 67 ARG 68 -0.0001

ARG 68 ARG 69 0.0001

ARG 69 ASP 70 -0.0002

ASP 70 LEU 71 -0.0001

LEU 71 LYS 72 0.0002

LYS 72 GLN 73 0.0003

GLN 73 LEU 74 0.0001

LEU 74 TYR 75 -0.0097

TYR 75 PHE 76 0.0002

PHE 76 ASN 77 -0.0001

ASN 77 LEU 78 -0.0000

LEU 78 TYR 79 0.0003

TYR 79 ILE 80 0.0003

ILE 80 THR 81 -0.0002

THR 81 VAL 82 -0.0001

VAL 82 ASN 83 0.0035

ASN 83 THR 84 -0.0001

THR 84 MET 85 0.0002

MET 85 ASN 86 -0.0001

ASN 86 LEU 87 -0.0003

LEU 87 PRO 88 0.0001

PRO 88 LYS 89 0.0002

LYS 89 ARG 90 0.0001

ARG 90 LYS 91 -0.0011

LYS 91 GLU 92 -0.0002

GLU 92 VAL 93 -0.0002

VAL 93 ILE 94 0.0004

ILE 94 CYS 95 -0.0001

CYS 95 ARG 96 0.0001

ARG 96 GLY 97 -0.0004

GLY 97 SER 98 -0.0001

SER 98 ASP 99 0.0057

ASP 99 ASP 100 0.0000

ASP 100 ASP 101 0.0001

ASP 101 TYR 102 0.0002

TYR 102 SER 103 -0.0003

SER 103 PHE 104 -0.0000

PHE 104 CYS 105 -0.0001

CYS 105 ARG 106 0.0000

ARG 106 ALA 107 -0.0230

ALA 107 LEU 108 -0.0000

LEU 108 LYS 109 0.0003

LYS 109 GLY 110 0.0002

GLY 110 GLU 111 -0.0002

GLU 111 THR 112 0.0003

THR 112 VAL 113 -0.0000

VAL 113 ASN 114 -0.0000

ASN 114 THR 115 0.0258

THR 115 THR 116 0.0002

THR 116 ILE 117 -0.0001

ILE 117 SER 118 0.0003

SER 118 PHE 119 -0.0002

PHE 119 SER 120 0.0002

SER 120 PHE 121 -0.0003

PHE 121 LYS 122 0.0003

LYS 122 GLY 123 0.0946

GLY 123 ILE 124 0.0001

ILE 124 LYS 125 -0.0003

LYS 125 PHE 126 0.0001

PHE 126 SER 127 -0.0002

SER 127 LYS 128 -0.0000

LYS 128 GLY 129 0.0004

GLY 129 LYS 130 0.0001

LYS 130 TYR 131 -0.0028

TYR 131 LYS 132 0.0001

LYS 132 CYS 133 -0.0003

CYS 133 VAL 134 0.0002

VAL 134 VAL 135 -0.0001

VAL 135 GLU 136 0.0002

GLU 136 ALA 137 0.0003

ALA 137 ILE 138 -0.0001

ILE 138 SER 139 -0.0044

SER 139 GLY 140 0.0002

GLY 140 SER 141 -0.0002

SER 141 PRO 142 0.0003

PRO 142 GLU 143 -0.0004

GLU 143 GLU 144 0.0001

GLU 144 MET 145 -0.0000

MET 145 LEU 146 0.0001

LEU 146 PHE 147 0.0123

PHE 147 CYS 148 -0.0006

CYS 148 LEU 149 -0.0001

LEU 149 GLU 150 0.0003

GLU 150 PHE 151 -0.0002

PHE 151 VAL 152 0.0001

VAL 152 ILE 153 -0.0001

ILE 153 LEU 154 -0.0001

LEU 154 HIS 155 0.0144

HIS 155 GLN 156 -0.0002

GLN 156 PRO 157 0.0002

PRO 157 ASN 158 0.0001

ASN 158 GLN 19 0.0219

GLN 19 LYS 20 0.0005

LYS 20 GLN 21 -0.0003

GLN 21 TYR 22 0.0003

TYR 22 TRP 23 -0.0000

TRP 23 VAL 24 -0.0001

VAL 24 CYS 25 0.0000

CYS 25 ASN 26 -0.0001

ASN 26 SER 27 -0.0097

SER 27 SER 28 -0.0001

SER 28 ASP 29 -0.0001

ASP 29 ALA 30 0.0002

ALA 30 SER 31 -0.0000

SER 31 ILE 32 -0.0001

ILE 32 SER 33 -0.0001

SER 33 TYR 34 -0.0002

TYR 34 THR 35 -0.0030

THR 35 TYR 36 -0.0001

TYR 36 CYS 37 0.0001

CYS 37 ASP 38 0.0002

ASP 38 LYS 39 -0.0002

LYS 39 MET 40 0.0002

MET 40 GLN 41 -0.0004

GLN 41 TYR 42 -0.0001

TYR 42 PRO 43 -0.0056

PRO 43 ILE 44 -0.0000

ILE 44 SER 45 -0.0001

SER 45 ILE 46 -0.0000

ILE 46 ASN 47 0.0003

ASN 47 VAL 48 0.0001

VAL 48 ASN 49 0.0001

ASN 49 PRO 50 -0.0003

PRO 50 CYS 51 0.0052

CYS 51 ILE 52 -0.0002

ILE 52 GLU 53 0.0002

GLU 53 LEU 54 -0.0000

LEU 54 LYS 55 -0.0004

LYS 55 GLY 56 -0.0002

GLY 56 SER 57 0.0003

SER 57 LYS 58 -0.0004

LYS 58 GLY 59 -0.0169

GLY 59 LEU 60 -0.0002

LEU 60 LEU 61 0.0003

LEU 61 HIS 62 -0.0004

HIS 62 ILE 63 -0.0002

ILE 63 PHE 64 0.0002

PHE 64 TYR 65 0.0000

TYR 65 ILE 66 -0.0000

ILE 66 PRO 67 -0.0032

PRO 67 ARG 68 -0.0003

ARG 68 ARG 69 0.0004

ARG 69 ASP 70 0.0000

ASP 70 LEU 71 0.0003

LEU 71 LYS 72 0.0003

LYS 72 GLN 73 -0.0000

GLN 73 LEU 74 -0.0004

LEU 74 TYR 75 0.0097

TYR 75 PHE 76 0.0000

PHE 76 ASN 77 0.0002

ASN 77 LEU 78 0.0002

LEU 78 TYR 79 -0.0001

TYR 79 ILE 80 -0.0001

ILE 80 THR 81 0.0003

THR 81 VAL 82 -0.0001

VAL 82 ASN 83 -0.0033

ASN 83 THR 84 0.0002

THR 84 MET 85 0.0004

MET 85 ASN 86 -0.0002

ASN 86 LEU 87 0.0001

LEU 87 PRO 88 0.0001

PRO 88 LYS 89 -0.0000

LYS 89 ARG 90 0.0002

ARG 90 LYS 91 0.0009

LYS 91 GLU 92 -0.0003

GLU 92 VAL 93 -0.0001

VAL 93 ILE 94 -0.0000

ILE 94 CYS 95 0.0003

CYS 95 ARG 96 0.0002

ARG 96 GLY 97 -0.0002

GLY 97 SER 98 0.0001

SER 98 ASP 99 -0.0052

ASP 99 ASP 100 0.0004

ASP 100 ASP 101 -0.0002

ASP 101 TYR 102 -0.0001

TYR 102 SER 103 -0.0000

SER 103 PHE 104 -0.0003

PHE 104 CYS 105 0.0001

CYS 105 ARG 106 0.0002

ARG 106 ALA 107 0.0226

ALA 107 LEU 108 0.0006

LEU 108 LYS 109 -0.0002

LYS 109 GLY 110 0.0000

GLY 110 GLU 111 0.0001

GLU 111 THR 112 -0.0002

THR 112 VAL 113 -0.0002

VAL 113 ASN 114 -0.0001

ASN 114 THR 115 -0.0262

THR 115 THR 116 0.0000

THR 116 ILE 117 0.0003

ILE 117 SER 118 0.0000

SER 118 PHE 119 0.0001

PHE 119 SER 120 -0.0004

SER 120 PHE 121 0.0002

PHE 121 LYS 122 0.0001

LYS 122 GLY 123 -0.0947

GLY 123 ILE 124 -0.0001

ILE 124 LYS 125 -0.0000

LYS 125 PHE 126 0.0001

PHE 126 SER 127 -0.0002

SER 127 LYS 128 -0.0001

LYS 128 GLY 129 0.0001

GLY 129 LYS 130 0.0001

LYS 130 TYR 131 0.0028

TYR 131 LYS 132 -0.0001

LYS 132 CYS 133 0.0005

CYS 133 VAL 134 0.0000

VAL 134 VAL 135 0.0001

VAL 135 GLU 136 0.0004

GLU 136 ALA 137 0.0002

ALA 137 ILE 138 -0.0002

ILE 138 SER 139 0.0043

SER 139 GLY 140 0.0002

GLY 140 SER 141 -0.0003

SER 141 PRO 142 -0.0001

PRO 142 GLU 143 -0.0003

GLU 143 GLU 144 0.0005

GLU 144 MET 145 0.0000

MET 145 LEU 146 -0.0000

LEU 146 PHE 147 -0.0119

PHE 147 CYS 148 0.0003

CYS 148 LEU 149 -0.0000

LEU 149 GLU 150 -0.0002

GLU 150 PHE 151 -0.0000

PHE 151 VAL 152 -0.0000

VAL 152 ILE 153 0.0001

ILE 153 LEU 154 -0.0002

LEU 154 HIS 155 -0.0141

HIS 155 GLN 156 -0.0000

GLN 156 PRO 157 -0.0000

PRO 157 ASN 158 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** TLR4-MD2 complete ***

CA strain for 240327122700959456

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.

* TLR4-MD2 complete *