Should you encounter any unexpected behaviour,
please let us know.

* *

CA distance fluctuations for 2403120153442850967

--- normal mode 21 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLY 47 0.11 SER 7 -0.40 GLY 25

GLY 47 0.16 ASN 8 -0.38 GLY 25

GLY 47 0.13 MET 9 -0.42 GLY 25

GLY 47 0.08 SER 10 -0.45 GLY 25

LEU 81 0.11 LEU 11 -0.41 GLY 25

LEU 81 0.14 VAL 12 -0.39 ASP 10

LEU 83 0.10 LYS 13 -0.44 GLY 25

LEU 83 0.10 GLU 14 -0.44 GLY 37

LEU 81 0.15 THR 15 -0.49 ASP 10

VAL 87 0.14 VAL 16 -0.40 GLY 25

VAL 87 0.11 ASP 17 -0.56 GLY 37

VAL 124 0.08 ARG 18 -0.51 ASP 10

VAL 124 0.10 LEU 19 -0.51 ASP 10

VAL 124 0.06 LEU 20 -0.41 GLY 37

VAL 124 0.05 LYS 21 -0.47 THR 13

VAL 124 0.04 GLY 22 -0.58 THR 16

VAL 124 0.04 TYR 23 -0.48 THR 16

PRO 29 0.03 ASP 24 -0.40 LEU 19

LEU 357 0.01 ILE 25 -0.31 GLY 25

LEU 357 0.02 ARG 26 -0.36 ASP 24

LEU 357 0.03 LEU 27 -0.28 GLY 25

LEU 357 0.04 ARG 28 -0.26 GLY 25

LEU 357 0.04 PRO 29 -0.27 GLY 25

PRO 34 0.05 ASP 30 -0.26 GLY 25

THR 12 0.08 PHE 31 -0.26 GLY 25

ASN 11 0.16 GLY 32 -0.25 GLY 25

PRO 34 0.13 GLY 33 -0.24 GLY 25

GLY 33 0.13 PRO 34 -0.22 GLY 25

GLY 33 0.09 PRO 35 -0.22 GLY 25

LEU 357 0.06 VAL 36 -0.23 GLY 25

LEU 357 0.07 ALA 37 -0.21 GLY 25

LEU 357 0.07 VAL 38 -0.21 GLY 25

LEU 357 0.08 GLY 39 -0.20 GLY 25

LEU 357 0.09 MET 40 -0.18 GLY 25

LEU 357 0.09 ASN 41 -0.17 GLY 25

LEU 357 0.10 ILE 42 -0.15 GLY 25

ILE 42 0.10 ASP 43 -0.14 GLY 25

LEU 357 0.10 ILE 44 -0.13 GLY 25

ARG 114 0.09 ALA 45 -0.12 GLY 25

GLN 152 0.11 SER 46 -0.11 GLY 25

GLN 152 0.13 ILE 47 -0.10 GLY 25

MET 70 0.13 ASP 48 -0.09 ASP 27

ASN 69 0.19 MET 49 -0.09 ASP 27

ASN 69 0.14 VAL 50 -0.09 ASP 27

PRO 52 0.15 SER 51 -0.09 THR 271

LYS 289 0.16 GLU 52 -0.10 LEU 272

ILE 68 0.14 VAL 53 -0.20 LEU 272

PRO 52 0.16 ASN 54 -0.12 LEU 272

PRO 52 0.17 MET 55 -0.09 LEU 272

PRO 52 0.13 ASP 56 -0.10 ASP 27

ASN 69 0.13 TYR 57 -0.10 ASP 27

MET 70 0.10 THR 58 -0.10 ASP 27

GLN 152 0.09 LEU 59 -0.11 GLY 25

ARG 114 0.08 THR 60 -0.12 GLY 25

LEU 357 0.08 MET 61 -0.13 GLY 25

THR 15 0.08 TYR 62 -0.16 GLY 25

LEU 357 0.07 PHE 63 -0.17 GLY 25

PRO 78 0.07 GLN 64 -0.19 GLY 25

THR 123 0.07 GLN 65 -0.21 GLY 25

THR 123 0.11 ALA 66 -0.22 GLY 25

LEU 357 0.07 TRP 67 -0.24 GLY 25

LEU 357 0.06 ARG 68 -0.26 GLY 25

LEU 357 0.05 ASP 69 -0.28 GLY 25

ARG 68 0.06 LYS 70 -0.44 ASN 11

LEU 357 0.05 ARG 71 -0.50 THR 12

VAL 124 0.08 LEU 72 -0.42 ASP 10

VAL 124 0.07 SER 73 -0.48 ASP 10

THR 216 0.08 TYR 74 -0.47 ASP 10

PRO 120 0.09 ASN 75 -0.42 ASP 10

SER 217 0.09 VAL 76 -0.39 ASP 10

SER 217 0.11 ILE 77 -0.34 ASP 10

SER 217 0.13 PRO 78 -0.30 ASP 10

GLY 218 0.11 LEU 79 -0.30 ASP 10

SER 217 0.12 ASN 80 -0.29 ASP 10

THR 15 0.15 LEU 81 -0.31 ASP 10

THR 15 0.13 THR 82 -0.28 GLY 25

THR 15 0.14 LEU 83 -0.31 GLY 25

THR 15 0.11 ASP 84 -0.30 GLY 25

THR 15 0.10 ASN 85 -0.25 GLY 25

VAL 16 0.09 ARG 86 -0.37 ALA 88

VAL 16 0.14 VAL 87 -0.41 ALA 88

VAL 16 0.10 ALA 88 -0.41 VAL 87

VAL 16 0.07 ASP 89 -0.31 GLY 25

VAL 16 0.06 GLN 90 -0.35 GLY 25

VAL 16 0.05 LEU 91 -0.31 GLY 25

LEU 357 0.04 TRP 92 -0.28 GLY 25

VAL 16 0.04 VAL 93 -0.25 GLY 25

LEU 357 0.05 PRO 94 -0.22 GLY 25

ILE 18 0.05 ASP 95 -0.19 GLY 25

LEU 357 0.06 THR 96 -0.18 GLY 25

LEU 357 0.06 TYR 97 -0.16 GLY 25

LEU 357 0.08 PHE 98 -0.14 GLY 25

LEU 357 0.08 LEU 99 -0.13 GLY 25

LEU 357 0.09 ASN 100 -0.12 GLY 25

THR 134 0.08 ASP 101 -0.12 GLY 25

THR 134 0.12 LYS 102 -0.10 ASP 27

VAL 108 0.10 LYS 103 -0.11 ASP 27

THR 132 0.08 SER 104 -0.12 ASP 27

VAL 108 0.06 PHE 105 -0.13 ASP 27

THR 15 0.06 VAL 106 -0.14 ASP 27

THR 15 0.06 HIS 107 -0.14 ASP 27

THR 15 0.05 GLY 108 -0.16 ASP 27

ILE 30 0.06 VAL 109 -0.16 ASP 27

ILE 30 0.07 THR 110 -0.18 ASP 27

THR 15 0.05 VAL 111 -0.21 ASP 27

THR 15 0.06 LYS 112 -0.20 ASP 27

THR 15 0.07 ASN 113 -0.18 ASP 27

THR 15 0.09 ARG 114 -0.20 GLY 25

THR 15 0.11 MET 115 -0.22 GLY 25

THR 15 0.12 ILE 116 -0.26 GLY 25

THR 15 0.13 ARG 117 -0.27 GLY 25

THR 15 0.12 LEU 118 -0.29 GLY 25

SER 217 0.10 HIS 119 -0.30 ASP 10

ASN 75 0.09 PRO 120 -0.35 ASP 10

THR 216 0.09 ASP 121 -0.34 ASP 10

THR 216 0.08 GLY 122 -0.35 ASP 10

ALA 66 0.11 THR 123 -0.26 GLY 25

LEU 19 0.10 VAL 124 -0.26 GLY 25

THR 15 0.10 LEU 125 -0.23 GLY 25

THR 15 0.08 TYR 126 -0.23 GLY 25

THR 15 0.08 GLY 127 -0.20 GLY 25

THR 15 0.07 LEU 128 -0.19 GLY 25

THR 15 0.07 ARG 129 -0.16 GLY 25

ARG 114 0.06 ILE 130 -0.14 GLY 25

VAL 108 0.08 THR 131 -0.12 ASP 27

THR 134 0.10 THR 132 -0.11 GLY 25

MET 70 0.10 THR 133 -0.12 SER 104

ASP 63 0.09 ALA 134 -0.11 GLY 25

GLY 51 0.12 ALA 135 -0.10 GLY 25

SER 49 0.12 CYS 136 -0.10 GLY 25

ARG 187 0.17 MET 137 -0.09 GLY 25

SER 186 0.12 MET 138 -0.09 GLY 25

ASP 192 0.13 ASP 139 -0.08 GLY 25

SER 291 0.14 LEU 140 -0.08 GLY 25

SER 291 0.13 ARG 141 -0.07 GLY 25

GLY 224 0.12 ARG 142 -0.08 GLY 25

SER 291 0.14 TYR 143 -0.08 ASP 27

SER 291 0.16 PRO 144 -0.08 ASP 27

LEU 357 0.14 LEU 145 -0.08 GLY 25

LEU 357 0.14 ASP 146 -0.08 GLY 25

LEU 357 0.14 GLU 147 -0.09 GLY 25

LEU 357 0.13 GLN 148 -0.09 GLY 25

ASP 184 0.14 ASN 149 -0.10 GLY 25

ASP 184 0.14 CYS 150 -0.11 GLY 25

LEU 357 0.12 THR 151 -0.12 GLY 25

LEU 357 0.11 LEU 152 -0.13 GLY 25

LEU 357 0.10 GLU 153 -0.14 GLY 25

LEU 357 0.09 ILE 154 -0.15 GLY 25

LEU 357 0.08 GLU 155 -0.16 GLY 25

LEU 357 0.07 SER 156 -0.18 GLY 25

ILE 18 0.07 TYR 157 -0.18 GLY 25

ILE 18 0.10 GLY 158 -0.19 GLY 25

PHE 15 0.09 TYR 159 -0.20 GLY 25

PHE 15 0.09 THR 160 -0.19 GLY 25

GLY 32 0.07 THR 161 -0.18 GLY 25

GLY 32 0.10 ASP 162 -0.20 GLY 25

GLY 32 0.10 ASP 163 -0.21 GLY 25

LEU 357 0.07 ILE 164 -0.21 GLY 25

LEU 357 0.08 GLU 165 -0.20 GLY 25

LEU 357 0.08 PHE 166 -0.19 GLY 25

LEU 357 0.09 TYR 167 -0.18 GLY 25

LEU 357 0.10 TRP 168 -0.17 GLY 25

LEU 357 0.10 ARG 169 -0.18 GLY 25

LEU 357 0.11 GLY 170 -0.17 GLY 25

LEU 357 0.12 ASP 171 -0.16 GLY 25

LEU 357 0.14 ASP 172 -0.15 GLY 25

LEU 357 0.13 ASN 173 -0.15 GLY 25

LEU 357 0.12 ALA 174 -0.16 GLY 25

LEU 357 0.12 VAL 175 -0.14 GLY 25

LEU 357 0.14 THR 176 -0.13 GLY 25

VAL 213 0.16 GLY 177 -0.12 GLY 25

LEU 357 0.15 VAL 178 -0.11 GLY 25

LEU 357 0.18 THR 179 -0.11 GLY 25

LEU 357 0.18 LYS 180 -0.10 GLY 25

LEU 357 0.16 ILE 181 -0.10 GLY 25

GLN 154 0.20 GLU 182 -0.09 GLY 25

GLN 154 0.16 LEU 183 -0.09 ASP 27

LEU 155 0.17 PRO 184 -0.08 ASP 27

VAL 290 0.19 GLN 185 -0.08 ASP 27

LEU 357 0.15 PHE 186 -0.09 GLY 25

LEU 357 0.21 SER 187 -0.10 LEU 214

LEU 357 0.19 ILE 188 -0.10 GLY 25

LEU 357 0.19 VAL 189 -0.10 GLY 25

LEU 357 0.17 ASP 190 -0.11 GLY 25

LEU 357 0.15 TYR 191 -0.12 GLY 25

LEU 357 0.14 LYS 192 -0.13 GLY 25

LEU 357 0.12 LEU 193 -0.14 GLY 25

LEU 357 0.11 ILE 194 -0.14 GLY 25

LEU 357 0.10 THR 195 -0.15 GLY 25

LEU 357 0.10 LYS 196 -0.15 GLY 25

LEU 357 0.09 LYS 197 -0.16 GLY 25

LEU 357 0.09 VAL 198 -0.15 GLY 25

MET 81 0.09 VAL 199 -0.15 GLY 25

MET 81 0.10 PHE 200 -0.15 GLY 25

MET 81 0.12 SER 201 -0.15 GLY 25

VAL 83 0.13 THR 202 -0.16 GLY 25

MET 81 0.13 GLY 203 -0.17 GLY 25

MET 81 0.10 SER 204 -0.17 GLY 25

MET 81 0.09 TYR 205 -0.17 GLY 25

LEU 357 0.08 PRO 206 -0.17 GLY 25

LEU 357 0.09 ARG 207 -0.16 GLY 25

LEU 357 0.10 LEU 208 -0.15 GLY 25

LEU 357 0.11 SER 209 -0.14 GLY 25

LEU 357 0.12 LEU 210 -0.14 GLY 25

LEU 357 0.13 SER 211 -0.12 GLY 25

LEU 357 0.15 PHE 212 -0.11 GLY 25

LEU 214 0.19 LYS 213 -0.10 GLY 25

LYS 213 0.19 LEU 214 -0.10 SER 187

LEU 357 0.16 LYS 215 -0.09 GLY 25

SER 291 0.19 ARG 216 -0.09 GLY 25

SER 291 0.26 ASN 217 -0.08 GLY 25

LEU 357 0.17 ILE 218 -0.08 ASP 27

VAL 293 0.22 GLY 219 -0.08 ASP 27

VAL 293 0.18 TYR 220 -0.08 ASP 27

SER 353 0.13 PHE 221 -0.08 ASP 27

SER 353 0.14 ILE 222 -0.07 ASP 27

LEU 298 0.19 LEU 223 -0.07 ASP 27

ASP 297 0.15 GLN 224 -0.08 ASP 27

ILE 228 0.12 THR 225 -0.08 ASP 27

SER 301 0.13 TYR 226 -0.08 ASP 27

SER 301 0.17 MET 227 -0.07 ASP 27

SER 301 0.14 PRO 228 -0.07 ASP 27

SER 301 0.11 SER 229 -0.07 ASP 27

SER 301 0.11 ILE 230 -0.07 ASP 27

VAL 302 0.12 LEU 231 -0.07 ASP 27

VAL 273 0.10 ILE 232 -0.07 ASP 27

VAL 349 0.10 THR 233 -0.07 ASP 27

PHE 308 0.12 ILE 234 -0.06 ASP 27

PHE 308 0.12 LEU 235 -0.06 ASP 27

PHE 308 0.08 SER 236 -0.07 ASP 27

VAL 312 0.10 TRP 237 -0.06 ASP 27

VAL 312 0.14 VAL 238 -0.06 ASP 27

VAL 312 0.08 SER 239 -0.06 ASP 27

GLY 315 0.09 PHE 240 -0.06 ASP 27

GLY 315 0.14 TRP 241 -0.06 ASP 27

GLY 315 0.09 ILE 242 -0.06 ASP 27

LYS 312 0.09 ASN 243 -0.06 LYS 312

LYS 312 0.08 TYR 244 -0.06 LYS 312

LYS 312 0.09 ASP 245 -0.08 LYS 312

LYS 312 0.09 ALA 246 -0.07 LYS 312

LYS 312 0.07 SER 247 -0.08 SER 251

PRO 253 0.07 ALA 248 -0.07 VAL 252

PRO 263 0.09 ALA 249 -0.06 ASP 27

PRO 263 0.07 ARG 250 -0.06 ASP 27

PRO 253 0.06 VAL 251 -0.06 ASP 27

PRO 253 0.07 ALA 252 -0.06 ASP 27

SER 267 0.08 LEU 253 -0.06 ASP 27

ILE 270 0.06 GLY 254 -0.07 ASP 27

LEU 240 0.06 ILE 255 -0.07 ASP 27

VAL 260 0.07 THR 256 -0.07 ASP 27

ILE 270 0.09 THR 257 -0.07 ASP 27

MET 236 0.09 VAL 258 -0.07 ASP 27

THR 237 0.08 LEU 259 -0.07 ASP 27

LEU 274 0.11 THR 260 -0.08 ASP 27

LEU 274 0.09 MET 261 -0.07 ASP 27

PRO 233 0.10 THR 262 -0.07 ASP 27

THR 268 0.11 THR 263 -0.08 ASP 27

THR 277 0.14 ILE 264 -0.08 ASP 27

THR 281 0.11 ASN 265 -0.08 LEU 268

THR 281 0.11 THR 266 -0.08 ASP 27

THR 281 0.16 HIS 267 -0.09 LYS 103

THR 281 0.22 LEU 268 -0.09 VAL 53

THR 281 0.16 ARG 269 -0.09 VAL 53

LYS 285 0.17 GLU 270 -0.09 VAL 53

LYS 285 0.22 THR 271 -0.16 VAL 53

LYS 289 0.22 LEU 272 -0.20 VAL 53

LYS 289 0.18 PRO 273 -0.09 LYS 102

LYS 289 0.15 LYS 274 -0.08 ASP 27

LYS 289 0.15 ILE 275 -0.07 ASP 27

LYS 222 0.13 PRO 276 -0.07 ASP 27

GLY 224 0.19 TYR 277 -0.07 ASP 27

GLY 224 0.19 VAL 278 -0.07 ASP 27

GLY 224 0.13 LYS 279 -0.08 ASP 27

SER 353 0.12 ALA 280 -0.08 ASP 27

SER 353 0.12 ILE 281 -0.08 ASP 27

ILE 228 0.15 ASP 282 -0.07 ASP 27

GLY 224 0.12 MET 283 -0.07 ASP 27

SER 353 0.11 TYR 284 -0.07 ASP 27

ILE 228 0.12 LEU 285 -0.07 ASP 27

GLY 334 0.11 MET 286 -0.08 ASP 27

SER 353 0.10 GLY 287 -0.07 ASP 27

SER 301 0.11 CYS 288 -0.07 ASP 27

SER 301 0.09 PHE 289 -0.07 ASP 27

GLY 334 0.10 VAL 290 -0.07 ASP 27

VAL 349 0.09 PHE 291 -0.07 ASP 27

VAL 349 0.08 VAL 292 -0.07 ASP 27

PRO 330 0.08 PHE 293 -0.07 ASP 27

ILE 327 0.08 MET 294 -0.07 ASP 27

VAL 349 0.08 ALA 295 -0.06 ASP 27

VAL 349 0.06 LEU 296 -0.06 ASP 27

ILE 327 0.07 LEU 297 -0.07 ASP 27

VAL 349 0.07 GLU 298 -0.06 ASP 27

VAL 349 0.06 TYR 299 -0.06 ASP 27

ARG 323 0.06 ALA 300 -0.06 ASP 27

ARG 323 0.06 LEU 301 -0.06 ASP 27

LYS 312 0.06 VAL 302 -0.06 ASP 27

LYS 312 0.06 ASN 303 -0.06 ASP 27

LYS 312 0.06 TYR 304 -0.07 ILE 322

LYS 312 0.06 ILE 305 -0.06 ILE 322

LYS 312 0.07 PHE 306 -0.06 ILE 322

LYS 312 0.06 PHE 307 -0.06 ILE 322

LYS 312 0.06 SER 308 -0.06 ILE 322

LYS 312 0.07 GLN 309 -0.05 ILE 322

LYS 312 0.08 PRO 310 -0.05 ASP 27

TYR 319 0.08 ALA 311 -0.05 ASP 27

TYR 319 0.08 ARG 312 -0.05 ASP 27

TYR 319 0.08 ALA 313 -0.06 ASP 27

TYR 319 0.10 ALA 314 -0.05 ASP 27

THR 316 0.08 ALA 315 -0.05 ASP 27

VAL 349 0.08 ILE 316 -0.06 ASP 27

GLY 315 0.09 ASP 317 -0.06 ASP 27

THR 316 0.10 ARG 318 -0.05 ASP 27

VAL 349 0.10 TRP 319 -0.06 ASP 27

VAL 349 0.10 SER 320 -0.06 ASP 27

VAL 312 0.12 ARG 321 -0.06 ASP 27

VAL 349 0.12 ILE 322 -0.05 ASP 27

VAL 349 0.12 PHE 323 -0.06 ASP 27

VAL 349 0.11 PHE 324 -0.06 ASP 27

VAL 349 0.13 PRO 325 -0.06 ASP 27

VAL 349 0.13 VAL 326 -0.06 GLY 25

VAL 349 0.12 VAL 327 -0.06 ASP 27

VAL 349 0.12 PHE 328 -0.06 ASP 27

VAL 349 0.14 SER 329 -0.06 GLY 25

SER 353 0.13 PHE 330 -0.07 PHE 331

SER 353 0.12 PHE 331 -0.07 PHE 330

SER 353 0.13 ASN 332 -0.07 ASP 27

SER 353 0.14 ILE 333 -0.06 GLY 25

SER 353 0.13 VAL 334 -0.07 GLY 25

SER 353 0.13 TYR 335 -0.07 GLY 25

SER 353 0.15 TRP 336 -0.07 GLY 25

SER 353 0.14 LEU 337 -0.07 GLY 25

SER 353 0.13 TYR 338 -0.07 GLY 25

LEU 357 0.13 TYR 339 -0.07 GLY 25

LEU 357 0.15 VAL 340 -0.07 GLY 25

GLY 32 0.11 ASP 10 -0.51 LEU 19

GLY 32 0.16 ASN 11 -0.49 ARG 71

GLY 32 0.13 THR 12 -0.50 ARG 71

GLY 32 0.08 THR 13 -0.56 GLY 22

GLY 203 0.09 VAL 14 -0.44 GLY 22

TYR 159 0.09 PHE 15 -0.40 GLY 22

TYR 159 0.05 THR 16 -0.58 GLY 22

GLY 203 0.07 ARG 17 -0.54 GLY 22

LEU 84 0.12 ILE 18 -0.40 GLY 22

MET 90 0.10 LEU 19 -0.46 GLY 22

MET 90 0.05 ASP 20 -0.54 GLY 22

LEU 127 0.07 ARG 21 -0.43 GLY 22

LEU 127 0.09 LEU 22 -0.38 GLY 22

LEU 127 0.04 LEU 23 -0.38 GLY 22

LEU 127 0.05 ASP 24 -0.43 ASP 17

ASP 72 0.05 GLY 25 -0.56 ASP 17

LEU 127 0.04 TYR 26 -0.45 ASP 17

PRO 32 0.03 ASP 27 -0.39 VAL 16

MET 9 0.02 ASN 28 -0.28 GLU 36

LYS 13 0.05 ARG 29 -0.28 ASP 27

MET 9 0.05 LEU 30 -0.26 THR 13

ASN 346 0.03 ARG 31 -0.23 GLU 36

GLY 25 0.04 PRO 32 -0.23 GLU 36

ASN 346 0.04 GLY 33 -0.22 GLU 36

TYR 162 0.05 LEU 34 -0.24 ASP 10

ASN 8 0.07 GLY 35 -0.24 ASP 10

ALA 165 0.06 GLU 36 -0.22 ASP 10

ASN 346 0.04 ARG 37 -0.21 ASP 10

ASN 346 0.04 VAL 38 -0.19 GLU 36

ASN 346 0.04 THR 39 -0.20 GLU 36

ASN 346 0.05 GLU 40 -0.18 GLU 36

ASN 346 0.05 VAL 41 -0.18 GLU 36

THR 126 0.08 LYS 42 -0.16 GLY 37

THR 126 0.07 THR 43 -0.15 GLY 37

THR 126 0.08 ASP 44 -0.14 GLY 37

MET 81 0.07 ILE 45 -0.13 GLY 25

MET 81 0.08 PHE 46 -0.12 GLY 25

LEU 357 0.08 VAL 47 -0.12 GLY 25

LEU 357 0.09 THR 48 -0.12 GLY 25

CYS 136 0.12 SER 49 -0.11 GLY 25

MET 137 0.13 PHE 50 -0.10 GLY 25

MET 55 0.14 GLY 51 -0.10 GLY 25

MET 55 0.17 PRO 52 -0.09 ASP 27

ASN 54 0.13 VAL 53 -0.08 ASP 27

ASN 54 0.13 SER 54 -0.09 SER 276

VAL 53 0.13 ASP 55 -0.09 SER 276

VAL 53 0.13 HIS 56 -0.13 PRO 278

MET 49 0.14 ASP 57 -0.09 PRO 278

GLU 182 0.13 MET 58 -0.08 ASP 24

ASN 54 0.12 GLU 59 -0.09 ASP 24

ASN 54 0.12 TYR 60 -0.09 ASP 27

ASP 56 0.12 THR 61 -0.10 ASP 27

ALA 135 0.11 ILE 62 -0.10 GLY 25

ALA 135 0.11 ASP 63 -0.11 GLY 25

ALA 135 0.08 VAL 64 -0.12 GLY 25

LEU 357 0.07 PHE 65 -0.14 GLY 25

LEU 357 0.06 PHE 66 -0.14 GLY 25

MET 81 0.06 ARG 67 -0.16 GLY 37

THR 126 0.06 GLN 68 -0.17 GLY 37

THR 126 0.10 SER 69 -0.19 GLY 37

GLU 73 0.06 TRP 70 -0.20 GLY 37

GLU 73 0.11 LYS 71 -0.22 GLY 37

GLU 73 0.10 ASP 72 -0.24 GLU 36

LYS 71 0.11 GLU 73 -0.32 MET 9

ASP 72 0.06 ARG 74 -0.36 SER 10

LEU 127 0.08 LEU 75 -0.29 GLY 37

LEU 127 0.09 LYS 76 -0.29 SER 10

THR 202 0.08 PHE 77 -0.30 GLY 37

THR 202 0.09 LYS 78 -0.30 GLY 37

THR 202 0.10 GLY 79 -0.30 GLY 37

GLY 203 0.11 PRO 80 -0.28 GLY 37

THR 202 0.13 MET 81 -0.27 GLY 37

THR 202 0.12 THR 82 -0.25 GLY 37

THR 202 0.13 VAL 83 -0.24 GLY 37

ILE 18 0.12 LEU 84 -0.26 GLY 37

ILE 18 0.10 ARG 85 -0.23 GLY 25

ILE 18 0.12 LEU 86 -0.28 ASP 24

ILE 18 0.10 ASN 87 -0.24 GLY 25

ILE 18 0.08 ASN 88 -0.22 GLY 25

ILE 18 0.08 LEU 89 -0.25 GLY 25

LEU 19 0.10 MET 90 -0.31 ASP 24

LEU 22 0.06 ALA 91 -0.28 ASP 24

LEU 118 0.03 SER 92 -0.26 GLU 36

ASN 346 0.02 LYS 93 -0.30 ASP 24

ASN 346 0.02 ILE 94 -0.28 ASP 24

ASN 346 0.02 TRP 95 -0.24 GLU 36

LEU 22 0.03 THR 96 -0.22 GLU 36

SER 291 0.03 PRO 97 -0.19 GLU 36

THR 15 0.05 ASP 98 -0.17 GLU 36

THR 15 0.05 THR 99 -0.15 GLU 36

THR 132 0.05 PHE 100 -0.14 GLU 36

ASN 69 0.07 PHE 101 -0.12 GLU 36

GLY 177 0.08 HIS 102 -0.12 GLU 36

SER 51 0.08 ASN 103 -0.10 GLU 36

ASN 69 0.08 GLY 104 -0.10 GLU 36

ASN 69 0.09 LYS 105 -0.09 GLU 36

THR 132 0.09 LYS 106 -0.10 LYS 105

LYS 102 0.10 SER 107 -0.11 ASP 27

LYS 103 0.10 VAL 108 -0.13 ALA 109

THR 132 0.05 ALA 109 -0.13 GLY 25

THR 132 0.05 HIS 110 -0.14 GLY 25

ILE 18 0.04 ASN 111 -0.16 GLY 25

LEU 357 0.04 MET 112 -0.16 GLY 25

VAL 16 0.04 THR 113 -0.17 GLY 25

ILE 18 0.04 MET 114 -0.19 GLY 25

ILE 18 0.05 PRO 115 -0.19 GLY 25

ILE 18 0.06 ASN 116 -0.17 GLY 25

LEU 118 0.10 LYS 117 -0.18 GLY 25

LYS 117 0.10 LEU 118 -0.19 GLY 25

ILE 18 0.10 LEU 119 -0.22 ASP 24

ILE 18 0.09 ARG 120 -0.23 ASP 24

ILE 18 0.08 ILE 121 -0.25 ASP 24

THR 202 0.10 THR 122 -0.24 GLY 37

ARG 173 0.09 GLU 123 -0.26 GLY 37

ARG 173 0.10 ASP 124 -0.25 GLY 37

THR 172 0.08 GLY 125 -0.25 GLY 37

THR 172 0.10 THR 126 -0.23 GLY 37

LEU 22 0.09 LEU 127 -0.22 GLY 37

THR 126 0.09 LEU 128 -0.20 GLY 37

ILE 18 0.07 TYR 129 -0.19 GLY 37

ILE 18 0.07 THR 130 -0.17 GLY 25

ILE 18 0.05 MET 131 -0.16 GLY 25

LEU 357 0.06 ARG 132 -0.15 GLY 25

THR 132 0.08 LEU 133 -0.13 GLY 25

LYS 102 0.12 THR 134 -0.11 GLY 25

LYS 102 0.09 VAL 135 -0.10 GLY 25

SER 51 0.11 ARG 136 -0.10 SER 107

SER 51 0.10 ALA 137 -0.09 GLU 36

SER 46 0.11 GLU 138 -0.09 GLU 36

LYS 180 0.12 CYS 139 -0.08 GLU 36

GLU 182 0.16 PRO 140 -0.08 GLU 36

GLU 182 0.16 MET 141 -0.07 GLU 36

GLU 182 0.15 HIS 142 -0.07 GLU 36

SER 187 0.13 LEU 143 -0.06 GLU 36

SER 187 0.12 GLU 144 -0.06 GLU 36

SER 187 0.10 ASP 145 -0.06 GLU 36

SER 187 0.10 PHE 146 -0.06 ASP 27

LYS 289 0.11 PRO 147 -0.07 ASP 27

TYR 277 0.11 MET 148 -0.06 ASP 27

LYS 289 0.10 ASP 149 -0.07 ASP 27

LYS 289 0.10 ALA 150 -0.07 GLU 36

LYS 180 0.11 HIS 151 -0.08 GLU 36

LYS 180 0.11 ALA 152 -0.08 GLU 36

LYS 180 0.11 CYS 153 -0.09 GLU 36

LYS 180 0.10 PRO 154 -0.09 GLU 36

LYS 180 0.08 LEU 155 -0.10 GLU 36

GLY 177 0.08 LYS 156 -0.12 GLU 36

GLY 177 0.07 PHE 157 -0.13 GLU 36

GLY 177 0.06 GLY 158 -0.14 GLU 36

THR 15 0.05 SER 159 -0.16 GLU 36

THR 15 0.07 TYR 160 -0.16 GLU 36

THR 15 0.09 ALA 161 -0.17 GLU 36

VAL 12 0.08 TYR 162 -0.18 GLU 36

VAL 12 0.07 THR 163 -0.17 GLU 36

GLY 35 0.05 ARG 164 -0.16 GLU 36

GLY 35 0.07 ALA 165 -0.18 GLU 36

GLY 35 0.07 GLU 166 -0.19 GLU 36

ASN 346 0.04 VAL 167 -0.18 GLU 36

ASN 346 0.05 VAL 168 -0.17 GLU 36

SER 291 0.05 TYR 169 -0.16 GLU 36

THR 126 0.06 GLU 170 -0.15 GLU 36

THR 126 0.08 TRP 171 -0.14 GLY 37

THR 126 0.10 THR 172 -0.15 GLY 37

ASP 124 0.10 ARG 173 -0.14 GLY 37

ASP 124 0.09 GLU 174 -0.13 GLY 37

ASN 346 0.09 PRO 175 -0.12 GLY 37

ASN 346 0.10 ALA 176 -0.11 GLY 37

MET 81 0.09 ARG 177 -0.12 GLY 25

MET 81 0.08 SER 178 -0.12 GLY 37

SER 291 0.08 VAL 179 -0.12 GLY 25

MET 81 0.09 VAL 180 -0.11 GLY 25

SER 291 0.09 VAL 181 -0.11 GLY 25

LEU 357 0.10 ALA 182 -0.11 GLY 25

ASN 149 0.12 GLU 183 -0.10 GLY 25

CYS 150 0.14 ASP 184 -0.10 GLY 25

MET 137 0.13 GLY 185 -0.11 GLY 25

MET 137 0.16 SER 186 -0.10 GLY 25

MET 137 0.17 ARG 187 -0.09 GLY 25

LYS 289 0.12 LEU 188 -0.09 GLY 25

LYS 289 0.14 ASN 189 -0.08 GLY 25

LYS 289 0.15 GLN 190 -0.08 ASP 27

LYS 289 0.13 TYR 191 -0.08 GLY 25

ASP 139 0.13 ASP 192 -0.08 GLY 25

ASP 139 0.11 LEU 193 -0.09 GLY 25

SER 291 0.11 LEU 194 -0.09 GLY 25

SER 291 0.10 GLY 195 -0.09 GLY 25

SER 291 0.09 GLN 196 -0.09 GLY 25

PRO 175 0.08 THR 197 -0.10 GLU 36

SER 291 0.07 VAL 198 -0.11 GLU 36

LYS 180 0.08 ASP 199 -0.12 GLU 36

LYS 180 0.07 SER 200 -0.13 GLU 36

THR 179 0.07 GLY 201 -0.13 GLU 36

GLY 177 0.07 ILE 202 -0.14 GLU 36

GLY 177 0.09 VAL 203 -0.13 GLU 36

GLY 177 0.08 GLN 204 -0.14 GLU 36

PRO 78 0.08 SER 205 -0.14 GLY 25

PRO 78 0.10 SER 206 -0.15 GLY 25

PRO 78 0.10 THR 207 -0.16 GLY 25

PRO 78 0.10 GLY 208 -0.15 GLY 25

PRO 78 0.08 GLU 209 -0.15 GLU 36

THR 15 0.06 TYR 210 -0.15 GLU 36

GLY 177 0.06 VAL 211 -0.15 GLU 36

GLY 177 0.07 VAL 212 -0.14 GLU 36

LYS 180 0.07 MET 213 -0.13 GLU 36

LYS 180 0.08 THR 214 -0.12 GLU 36

LYS 180 0.08 THR 215 -0.11 GLU 36

PHE 217 0.11 HIS 216 -0.10 GLU 36

HIS 216 0.11 PHE 217 -0.09 GLY 25

SER 291 0.09 HIS 218 -0.08 GLY 25

LYS 289 0.10 LEU 219 -0.08 GLY 25

TYR 277 0.11 LYS 220 -0.07 GLY 25

TYR 277 0.12 ARG 221 -0.07 ASP 27

TYR 277 0.17 LYS 222 -0.07 ASP 27

TYR 277 0.14 ILE 223 -0.07 ASP 27

VAL 278 0.19 GLY 224 -0.07 ASP 27

LYS 289 0.14 TYR 225 -0.07 ASP 27

LYS 289 0.11 PHE 226 -0.07 ASP 27

ASP 282 0.11 VAL 227 -0.07 ASP 27

ASP 282 0.15 ILE 228 -0.07 ASP 27

THR 281 0.12 GLN 229 -0.07 ASP 27

THR 281 0.10 THR 230 -0.07 ASP 27

ASP 297 0.09 TYR 231 -0.07 ASP 27

LEU 285 0.10 LEU 232 -0.07 ASP 27

THR 262 0.10 PRO 233 -0.07 ASP 27

SER 301 0.08 CYS 234 -0.07 ASP 27

SER 301 0.08 ILE 235 -0.06 ASP 27

SER 301 0.09 MET 236 -0.06 ASP 27

LEU 259 0.08 THR 237 -0.07 ASP 27

SER 301 0.06 VAL 238 -0.06 ASP 27

PRO 330 0.08 ILE 239 -0.06 ASP 27

VAL 258 0.08 LEU 240 -0.06 ASP 27

VAL 258 0.05 SER 241 -0.06 ASP 27

SER 301 0.05 GLN 242 -0.07 PRO 325

ARG 326 0.06 VAL 243 -0.06 ILE 322

ILE 255 0.05 SER 244 -0.07 ILE 322

ASP 322 0.04 PHE 245 -0.09 ILE 322

LEU 297 0.05 TRP 246 -0.08 ILE 322

LYS 312 0.05 LEU 247 -0.07 ILE 322

LYS 312 0.04 ASN 248 -0.07 ILE 322

ALA 176 0.02 ARG 249 -0.08 ILE 322

LYS 312 0.03 GLU 250 -0.07 ASP 245

LYS 312 0.04 SER 251 -0.08 SER 247

LYS 312 0.02 VAL 252 -0.07 ALA 248

ALA 248 0.04 PRO 253 -0.08 PRO 263

LYS 312 0.05 ALA 254 -0.06 ASP 27

LYS 312 0.03 ARG 255 -0.07 VAL 238

ALA 249 0.04 THR 256 -0.07 VAL 238

ALA 248 0.05 VAL 257 -0.06 ASP 27

PRO 253 0.04 PHE 258 -0.06 ASP 27

ALA 300 0.04 GLY 259 -0.07 LEU 235

ALA 300 0.03 VAL 260 -0.07 ASN 101

VAL 257 0.05 THR 261 -0.07 ASP 27

ALA 300 0.04 THR 262 -0.07 ASP 27

VAL 257 0.03 VAL 263 -0.07 ASN 101

THR 256 0.06 LEU 264 -0.07 ASN 101

LEU 264 0.07 THR 265 -0.07 ASP 27

LEU 264 0.05 MET 266 -0.07 ASP 27

LEU 264 0.05 THR 267 -0.08 ASN 101

LEU 264 0.08 THR 268 -0.08 ASN 101

THR 268 0.08 LEU 269 -0.08 ASP 27

THR 268 0.06 SER 270 -0.08 ASN 101

THR 268 0.07 ILE 271 -0.08 ASN 101

THR 268 0.10 SER 272 -0.08 ASP 27

LYS 285 0.09 ALA 273 -0.08 ASP 27

LYS 285 0.09 ARG 274 -0.08 ASN 101

THR 271 0.12 ASN 275 -0.10 HIS 56

LYS 285 0.13 SER 276 -0.10 HIS 56

LYS 289 0.12 LEU 277 -0.10 HIS 56

THR 271 0.12 PRO 278 -0.13 HIS 56

GLN 185 0.13 LYS 279 -0.08 ASP 24

SER 187 0.13 VAL 280 -0.08 ASP 24

SER 187 0.13 ALA 281 -0.08 ASP 24

SER 187 0.12 TYR 282 -0.07 GLU 36

SER 187 0.09 ALA 283 -0.07 LYS 105

SER 187 0.09 THR 284 -0.07 LYS 105

LYS 289 0.08 ALA 285 -0.06 ASP 27

LYS 289 0.08 MET 286 -0.07 ASP 27

LYS 289 0.07 ASP 287 -0.07 ASN 101

LYS 289 0.07 TRP 288 -0.07 PHE 336

SER 291 0.07 PHE 289 -0.06 ASP 27

ASP 297 0.06 ILE 290 -0.07 ASP 27

ASP 297 0.04 ALA 291 -0.07 ASN 101

SER 291 0.05 VAL 292 -0.08 SER 329

SER 301 0.05 CYS 293 -0.06 SER 329

SER 301 0.04 TYR 294 -0.07 LEU 231

SER 299 0.04 ALA 295 -0.10 SER 329

SER 301 0.04 PHE 296 -0.09 SER 329

ALA 300 0.04 VAL 297 -0.07 SER 329

SER 301 0.03 PHE 298 -0.10 ILE 234

ALA 295 0.04 SER 299 -0.12 PRO 325

THR 262 0.04 ALA 300 -0.09 PRO 325

ALA 176 0.03 LEU 301 -0.09 PRO 325

TYR 309 0.04 ILE 302 -0.14 PRO 325

PHE 310 0.03 GLU 303 -0.13 ILE 322

VAL 307 0.04 PHE 304 -0.10 ILE 322

TYR 309 0.05 ALA 305 -0.15 VAL 238

PHE 310 0.07 THR 306 -0.17 ILE 322

PHE 304 0.04 VAL 307 -0.13 ILE 322

ALA 305 0.03 ASN 308 -0.11 ASN 243

THR 306 0.07 TYR 309 -0.17 ASN 243

THR 306 0.07 PHE 310 -0.16 ARG 318

THR 306 0.04 THR 311 -0.11 ALA 314

THR 306 0.03 LYS 312 -0.13 PRO 310

THR 306 0.04 SER 313 -0.17 ALA 311

THR 306 0.04 GLN 314 -0.15 ALA 311

ALA 176 0.03 PRO 315 -0.11 ALA 311

ALA 176 0.04 ALA 316 -0.12 ILE 322

ALA 176 0.04 ARG 317 -0.15 ILE 322

ALA 176 0.04 ALA 318 -0.13 ILE 322

LEU 297 0.04 ALA 319 -0.11 ILE 322

MET 294 0.04 LYS 320 -0.14 ILE 322

SER 325 0.05 ILE 321 -0.16 ILE 322

MET 294 0.05 ASP 322 -0.13 ILE 322

LEU 297 0.07 ARG 323 -0.12 ILE 322

MET 294 0.07 LEU 324 -0.14 ILE 322

MET 294 0.05 SER 325 -0.13 ILE 322

MET 294 0.08 ARG 326 -0.11 ILE 322

MET 294 0.08 ILE 327 -0.11 ILE 322

VAL 290 0.07 ALA 328 -0.12 VAL 326

VAL 290 0.07 PHE 329 -0.11 VAL 326

VAL 290 0.10 PRO 330 -0.09 VAL 326

VAL 290 0.09 LEU 331 -0.10 VAL 326

MET 283 0.08 LEU 332 -0.11 SER 329

MET 283 0.08 PHE 333 -0.09 SER 329

MET 283 0.11 GLY 334 -0.08 SER 329

MET 283 0.10 ILE 335 -0.10 SER 329

MET 283 0.09 PHE 336 -0.09 SER 329

MET 283 0.11 ASN 337 -0.07 SER 329

VAL 278 0.11 LEU 338 -0.07 SER 329

VAL 278 0.10 VAL 339 -0.08 ILE 333

VAL 278 0.10 TYR 340 -0.07 ILE 333

TYR 277 0.12 TRP 341 -0.05 ILE 333

TYR 277 0.12 ALA 342 -0.07 THR 343

TYR 277 0.10 THR 343 -0.07 ALA 342

TYR 277 0.11 TYR 344 -0.06 ASP 27

TYR 277 0.14 LEU 345 -0.05 ASP 27

TYR 277 0.12 ASN 346 -0.05 ASP 27

TYR 277 0.11 ARG 347 -0.05 GLU 36

GLY 208 0.06 SER 7 -0.27 GLU 73

GLY 35 0.07 ASN 8 -0.26 GLU 73

LEU 30 0.05 MET 9 -0.34 ARG 74

GLY 208 0.05 SER 10 -0.36 ARG 74

GLY 208 0.07 LEU 11 -0.28 GLU 36

LEU 83 0.10 VAL 12 -0.30 ASP 10

ASP 84 0.07 LYS 13 -0.45 GLY 25

LEU 83 0.07 GLU 14 -0.46 GLY 25

LEU 83 0.11 THR 15 -0.37 ASP 10

VAL 87 0.13 VAL 16 -0.43 GLY 25

VAL 87 0.08 ASP 17 -0.56 GLY 25

VAL 124 0.06 ARG 18 -0.43 GLY 25

VAL 124 0.07 LEU 19 -0.41 THR 13

VAL 124 0.04 LEU 20 -0.42 GLY 25

VAL 124 0.04 LYS 21 -0.43 THR 13

VAL 124 0.03 GLY 22 -0.57 THR 16

VAL 124 0.02 TYR 23 -0.45 THR 16

PRO 29 0.03 ASP 24 -0.40 GLY 25

PRO 34 0.00 ILE 25 -0.30 GLY 25

THR 12 0.03 ARG 26 -0.34 GLY 25

THR 12 0.04 LEU 27 -0.34 GLY 25

ASP 10 0.02 ARG 28 -0.30 GLY 25

ASP 24 0.03 PRO 29 -0.29 GLY 25

PRO 34 0.06 ASP 30 -0.30 GLY 25

THR 12 0.10 PHE 31 -0.33 GLY 25

ASN 11 0.17 GLY 32 -0.34 GLY 25

PRO 34 0.15 GLY 33 -0.31 GLY 25

GLY 33 0.15 PRO 34 -0.28 GLY 25

GLY 33 0.10 PRO 35 -0.26 GLY 25

THR 195 0.04 VAL 36 -0.25 GLY 25

THR 195 0.05 ALA 37 -0.23 GLY 25

THR 195 0.04 VAL 38 -0.21 GLY 25

SER 51 0.04 GLY 39 -0.19 GLY 25

PRO 78 0.05 MET 40 -0.17 GLY 25

PRO 78 0.06 ASN 41 -0.16 GLY 25

ASP 43 0.07 ILE 42 -0.14 GLY 25

SER 51 0.07 ASP 43 -0.13 GLY 25

ASN 54 0.08 ILE 44 -0.11 GLY 25

ASN 54 0.09 ALA 45 -0.11 GLY 25

GLU 138 0.11 SER 46 -0.10 GLU 36

ASN 54 0.10 ILE 47 -0.09 GLU 36

ASN 54 0.12 ASP 48 -0.08 GLU 36

ASP 57 0.14 MET 49 -0.08 ASN 101

ASP 57 0.11 VAL 50 -0.08 ASN 101

VAL 53 0.11 SER 51 -0.08 ASN 101

VAL 53 0.11 GLU 52 -0.08 ASN 101

VAL 53 0.11 VAL 53 -0.16 LEU 272

ILE 68 0.11 ASN 54 -0.09 THR 125

VAL 53 0.10 MET 55 -0.08 ASN 101

VAL 53 0.10 ASP 56 -0.09 ASN 101

ASN 54 0.10 TYR 57 -0.09 ASN 101

ASN 54 0.11 THR 58 -0.10 THR 132

ASN 54 0.10 LEU 59 -0.10 GLU 36

ASN 54 0.09 THR 60 -0.10 GLU 36

ASN 54 0.08 MET 61 -0.12 GLY 25

SER 51 0.06 TYR 62 -0.13 GLY 25

SER 51 0.05 PHE 63 -0.15 GLY 25

PRO 78 0.06 GLN 64 -0.17 GLY 25

THR 123 0.05 GLN 65 -0.19 GLY 25

THR 123 0.07 ALA 66 -0.21 GLY 25

SER 73 0.03 TRP 67 -0.23 GLY 25

LYS 70 0.04 ARG 68 -0.25 GLY 25

GLY 22 0.02 ASP 69 -0.28 GLY 25

ARG 68 0.04 LYS 70 -0.36 ASP 10

SER 206 0.02 ARG 71 -0.44 THR 12

VAL 124 0.06 LEU 72 -0.33 ASP 10

VAL 124 0.06 SER 73 -0.40 ASP 10

VAL 124 0.06 TYR 74 -0.38 ASP 10

PRO 120 0.08 ASN 75 -0.35 ASP 10

THR 207 0.07 VAL 76 -0.32 ASP 10

THR 207 0.08 ILE 77 -0.27 ASP 10

LEU 79 0.11 PRO 78 -0.25 ASP 10

PRO 78 0.11 LEU 79 -0.25 ASP 10

THR 207 0.09 ASN 80 -0.24 ASP 10

THR 15 0.11 LEU 81 -0.24 ASP 10

THR 15 0.10 THR 82 -0.22 GLU 36

THR 15 0.11 LEU 83 -0.25 ASP 27

THR 15 0.09 ASP 84 -0.23 GLU 36

THR 15 0.08 ASN 85 -0.21 GLU 36

VAL 16 0.08 ARG 86 -0.30 ALA 88

VAL 16 0.13 VAL 87 -0.31 ALA 88

VAL 16 0.10 ALA 88 -0.31 VAL 87

VAL 16 0.08 ASP 89 -0.27 GLU 36

VAL 16 0.08 GLN 90 -0.31 GLU 36

VAL 16 0.06 LEU 91 -0.28 ASP 27

VAL 16 0.03 TRP 92 -0.27 GLY 25

VAL 16 0.04 VAL 93 -0.24 GLY 25

VAL 16 0.03 PRO 94 -0.22 GLY 25

ILE 18 0.04 ASP 95 -0.20 GLY 25

GLY 32 0.05 THR 96 -0.17 GLY 25

MET 81 0.05 TYR 97 -0.15 GLY 25

SER 51 0.05 PHE 98 -0.13 GLY 25

MET 81 0.07 LEU 99 -0.12 GLY 25

ASN 54 0.07 ASN 100 -0.10 ASN 101

ASN 54 0.07 ASP 101 -0.10 ASN 101

MET 49 0.08 LYS 102 -0.10 ASN 101

LYS 117 0.07 LYS 103 -0.10 ASN 101

THR 132 0.06 SER 104 -0.12 THR 133

THR 132 0.06 PHE 105 -0.12 ASN 101

THR 15 0.06 VAL 106 -0.13 GLU 36

THR 132 0.06 HIS 107 -0.12 GLU 36

THR 132 0.05 GLY 108 -0.14 LYS 105

THR 132 0.06 VAL 109 -0.13 GLU 36

THR 132 0.04 THR 110 -0.14 GLU 36

THR 15 0.05 VAL 111 -0.16 GLU 36

THR 15 0.06 LYS 112 -0.17 GLU 36

THR 15 0.06 ASN 113 -0.16 GLU 36

MET 115 0.10 ARG 114 -0.17 GLU 36

ARG 114 0.10 MET 115 -0.18 GLU 36

THR 15 0.09 ILE 116 -0.21 GLU 36

THR 15 0.09 ARG 117 -0.21 GLU 36

THR 15 0.08 LEU 118 -0.24 ASP 27

PRO 78 0.08 HIS 119 -0.25 ASP 10

ASN 75 0.08 PRO 120 -0.29 ASP 10

SER 206 0.06 ASP 121 -0.30 ASP 10

VAL 124 0.07 GLY 122 -0.30 ASP 10

LEU 125 0.08 THR 123 -0.24 GLY 25

LEU 19 0.07 VAL 124 -0.23 GLY 25

THR 123 0.08 LEU 125 -0.20 GLY 25

THR 15 0.07 TYR 126 -0.20 GLY 25

THR 15 0.06 GLY 127 -0.17 GLY 25

THR 15 0.06 LEU 128 -0.16 GLU 36

THR 132 0.06 ARG 129 -0.14 GLU 36

THR 132 0.06 ILE 130 -0.12 GLU 36

THR 132 0.08 THR 131 -0.10 GLU 36

MET 49 0.08 THR 132 -0.10 THR 58

ASN 54 0.10 THR 133 -0.12 SER 104

ASN 54 0.09 ALA 134 -0.10 ASN 101

VAL 53 0.08 ALA 135 -0.09 ASN 101

VAL 53 0.08 CYS 136 -0.08 GLY 22

VAL 53 0.08 MET 137 -0.08 ASN 346

VAL 53 0.08 MET 138 -0.08 ASN 346

VAL 53 0.08 ASP 139 -0.10 ASN 346

LYS 285 0.08 LEU 140 -0.09 LEU 345

LYS 285 0.08 ARG 141 -0.11 ASN 346

LYS 285 0.07 ARG 142 -0.09 ASN 346

LYS 285 0.08 TYR 143 -0.07 ASN 346

LYS 285 0.08 PRO 144 -0.07 ASP 24

LYS 285 0.07 LEU 145 -0.07 ASP 24

LYS 285 0.07 ASP 146 -0.08 ASN 346

VAL 53 0.07 GLU 147 -0.08 ASN 346

VAL 53 0.08 GLN 148 -0.08 ASN 346

VAL 53 0.08 ASN 149 -0.11 LYS 213

VAL 53 0.09 CYS 150 -0.09 GLY 25

VAL 53 0.09 THR 151 -0.10 GLY 25

ASN 54 0.08 LEU 152 -0.11 GLY 25

ASN 54 0.06 GLU 153 -0.13 GLY 25

SER 51 0.05 ILE 154 -0.15 GLY 25

MET 81 0.06 GLU 155 -0.16 GLY 25

MET 81 0.06 SER 156 -0.19 GLY 25

MET 81 0.07 TYR 157 -0.19 GLY 25

PHE 15 0.09 GLY 158 -0.22 GLY 25

PHE 15 0.10 TYR 159 -0.24 GLY 25

MET 81 0.10 THR 160 -0.23 GLY 25

PRO 206 0.08 THR 161 -0.22 GLY 25

ASN 11 0.11 ASP 162 -0.25 GLY 25

GLY 32 0.10 ASP 163 -0.26 GLY 25

GLY 33 0.07 ILE 164 -0.24 GLY 25

THR 195 0.06 GLU 165 -0.21 GLY 25

THR 195 0.06 PHE 166 -0.19 GLY 25

THR 195 0.06 TYR 167 -0.18 GLY 25

VAL 53 0.05 TRP 168 -0.16 GLY 25

PRO 78 0.06 ARG 169 -0.17 GLY 25

PRO 78 0.07 GLY 170 -0.16 GLY 25

HIS 142 0.06 ASP 171 -0.16 GLY 25

HIS 142 0.07 ASP 172 -0.14 GLY 25

PRO 78 0.07 ASN 173 -0.14 GLY 25

PRO 78 0.07 ALA 174 -0.15 GLY 25

PRO 140 0.07 VAL 175 -0.14 GLY 25

PRO 140 0.08 THR 176 -0.13 GLY 25

PRO 140 0.11 GLY 177 -0.11 GLY 25

PRO 140 0.11 VAL 178 -0.11 GLY 25

PRO 140 0.12 THR 179 -0.10 GLY 25

PRO 140 0.16 LYS 180 -0.10 GLY 25

PRO 140 0.16 ILE 181 -0.09 GLY 25

PRO 140 0.16 GLU 182 -0.09 GLU 36

MET 58 0.12 LEU 183 -0.08 GLU 36

PRO 278 0.12 PRO 184 -0.08 ASP 24

LYS 279 0.13 GLN 185 -0.08 ASP 24

LYS 213 0.09 PHE 186 -0.08 GLU 36

HIS 142 0.13 SER 187 -0.13 LEU 214

HIS 142 0.11 ILE 188 -0.09 GLY 25

HIS 142 0.10 VAL 189 -0.09 GLY 25

HIS 142 0.09 ASP 190 -0.10 GLY 25

HIS 142 0.08 TYR 191 -0.11 GLY 25

VAL 53 0.07 LYS 192 -0.12 GLY 25

VAL 53 0.07 LEU 193 -0.13 GLY 25

VAL 53 0.06 ILE 194 -0.14 GLY 25

GLY 33 0.06 THR 195 -0.15 GLY 25

PRO 80 0.07 LYS 196 -0.15 GLY 25

MET 81 0.08 LYS 197 -0.16 GLY 25

MET 81 0.09 VAL 198 -0.16 GLY 25

MET 81 0.11 VAL 199 -0.16 GLY 25

MET 81 0.11 PHE 200 -0.16 GLY 25

MET 81 0.13 SER 201 -0.16 GLY 25

MET 81 0.15 THR 202 -0.19 GLY 25

MET 81 0.15 GLY 203 -0.20 GLY 25

MET 81 0.13 SER 204 -0.19 GLY 25

MET 81 0.11 TYR 205 -0.18 GLY 25

THR 161 0.08 PRO 206 -0.18 GLY 25

MET 81 0.06 ARG 207 -0.16 GLY 25

VAL 53 0.06 LEU 208 -0.15 GLY 25

VAL 53 0.06 SER 209 -0.13 GLY 25

VAL 53 0.07 LEU 210 -0.13 GLY 25

VAL 53 0.08 SER 211 -0.11 GLY 25

LEU 214 0.09 PHE 212 -0.10 GLY 25

LEU 214 0.21 LYS 213 -0.11 ASN 149

LYS 213 0.21 LEU 214 -0.13 SER 187

LYS 213 0.14 LYS 215 -0.10 SER 187

LYS 213 0.09 ARG 216 -0.08 ASP 24

ALA 281 0.10 ASN 217 -0.08 ASP 24

LYS 285 0.07 ILE 218 -0.07 ASP 24

LEU 223 0.07 GLY 219 -0.08 ASP 24

LYS 285 0.08 TYR 220 -0.08 ASP 24

LYS 285 0.07 PHE 221 -0.08 ASP 24

LYS 285 0.06 ILE 222 -0.07 ASP 24

GLY 219 0.07 LEU 223 -0.07 ASN 101

LYS 285 0.07 GLN 224 -0.08 ASN 101

LYS 285 0.06 THR 225 -0.08 ASN 101

LYS 285 0.05 TYR 226 -0.07 ASP 24

LYS 285 0.04 MET 227 -0.08 ALA 295

LYS 285 0.04 PRO 228 -0.08 ASN 101

LYS 285 0.03 SER 229 -0.07 ASN 101

LYS 285 0.03 ILE 230 -0.08 ALA 295

VAL 189 0.03 LEU 231 -0.10 ALA 295

PRO 228 0.03 ILE 232 -0.07 ASN 101

MET 81 0.03 THR 233 -0.08 ILE 302

ASP 172 0.03 ILE 234 -0.12 ILE 302

VAL 189 0.03 LEU 235 -0.09 ILE 302

MET 81 0.02 SER 236 -0.07 VAL 292

MET 81 0.02 TRP 237 -0.11 ILE 302

ASP 172 0.02 VAL 238 -0.15 ALA 305

MET 81 0.02 SER 239 -0.09 ALA 305

MET 81 0.02 PHE 240 -0.13 TYR 309

ASP 172 0.02 TRP 241 -0.15 THR 306

ASP 172 0.02 ILE 242 -0.13 TYR 309

MET 81 0.02 ASN 243 -0.17 TYR 309

MET 81 0.02 TYR 244 -0.12 TYR 309

MET 81 0.02 ASP 245 -0.10 SER 313

ALA 176 0.02 ALA 246 -0.10 ALA 261

VAL 257 0.03 SER 247 -0.11 ALA 254

VAL 257 0.05 ALA 248 -0.14 ALA 264

VAL 257 0.04 ALA 249 -0.10 PRO 263

LEU 264 0.02 ARG 250 -0.07 ALA 264

TYR 304 0.03 VAL 251 -0.07 ILE 124

THR 261 0.05 ALA 252 -0.07 SER 267

LEU 264 0.04 LEU 253 -0.06 ILE 124

LEU 264 0.03 GLY 254 -0.07 ILE 124

LEU 264 0.04 ILE 255 -0.07 ILE 124

LEU 264 0.06 THR 256 -0.07 ILE 124

THR 268 0.04 THR 257 -0.07 ILE 124

VAL 292 0.04 VAL 258 -0.07 ILE 124

THR 268 0.05 LEU 259 -0.08 ILE 124

THR 268 0.06 THR 260 -0.08 ILE 124

THR 268 0.04 MET 261 -0.07 ILE 124

HIS 267 0.05 THR 262 -0.08 ILE 124

THR 265 0.07 THR 263 -0.09 ILE 124

HIS 267 0.05 ILE 264 -0.08 ILE 124

HIS 267 0.06 ASN 265 -0.08 ILE 124

LEU 269 0.08 THR 266 -0.09 VAL 108

HIS 267 0.09 HIS 267 -0.09 VAL 108

ASN 275 0.11 LEU 268 -0.09 THR 125

GLU 270 0.10 ARG 269 -0.09 THR 125

GLU 270 0.13 GLU 270 -0.10 VAL 108

ASN 275 0.12 THR 271 -0.11 VAL 53

PRO 278 0.11 LEU 272 -0.16 VAL 53

SER 286 0.11 PRO 273 -0.10 THR 125

SER 286 0.11 LYS 274 -0.09 THR 125

SER 286 0.09 ILE 275 -0.10 LEU 345

SER 286 0.08 PRO 276 -0.13 LEU 345

SER 286 0.08 TYR 277 -0.13 LEU 345

LYS 285 0.07 VAL 278 -0.11 LEU 345

LYS 285 0.07 LYS 279 -0.09 LEU 345

LYS 285 0.06 ALA 280 -0.08 LEU 345

LYS 285 0.07 ILE 281 -0.07 LEU 345

LYS 285 0.07 ASP 282 -0.08 LEU 345

LYS 285 0.06 MET 283 -0.08 LEU 345

LYS 285 0.05 TYR 284 -0.07 LEU 345

LYS 285 0.06 LEU 285 -0.07 ASP 24

LYS 285 0.04 MET 286 -0.08 LEU 345

PHE 331 0.05 GLY 287 -0.08 LEU 338

LYS 285 0.04 CYS 288 -0.07 ILE 302

HIS 267 0.04 PHE 289 -0.07 LEU 338

MET 81 0.03 VAL 290 -0.09 LEU 338

MET 81 0.03 PHE 291 -0.08 THR 306

VAL 258 0.04 VAL 292 -0.08 THR 306

HIS 267 0.03 PHE 293 -0.08 GLY 334

MET 81 0.03 MET 294 -0.10 GLY 334

MET 81 0.03 ALA 295 -0.09 GLY 334

VAL 258 0.03 LEU 296 -0.09 GLY 334

HIS 267 0.03 LEU 297 -0.11 GLY 334

MET 81 0.03 GLU 298 -0.10 GLY 334

MET 81 0.03 TYR 299 -0.10 TYR 309

TYR 304 0.04 ALA 300 -0.10 VAL 243

ILE 305 0.03 LEU 301 -0.10 GLY 334

MET 81 0.03 VAL 302 -0.11 TYR 309

PHE 306 0.03 ASN 303 -0.10 SER 313

ALA 300 0.04 TYR 304 -0.09 SER 313

LEU 301 0.03 ILE 305 -0.11 SER 313

MET 81 0.03 PHE 306 -0.12 SER 313

MET 81 0.02 PHE 307 -0.12 SER 313

MET 81 0.03 SER 308 -0.12 SER 313

PRO 80 0.03 GLN 309 -0.14 SER 313

ALA 313 0.04 PRO 310 -0.17 SER 313

ALA 313 0.04 ALA 311 -0.17 SER 313

PRO 80 0.03 ARG 312 -0.14 SER 313

PRO 310 0.04 ALA 313 -0.12 SER 313

MET 81 0.03 ALA 314 -0.15 TYR 309

PRO 80 0.03 ALA 315 -0.14 PHE 310

PRO 80 0.03 ILE 316 -0.12 TYR 309

MET 81 0.03 ASP 317 -0.15 TYR 309

MET 81 0.03 ARG 318 -0.16 TYR 309

PRO 80 0.03 TRP 319 -0.13 THR 306

MET 81 0.03 SER 320 -0.12 THR 306

MET 81 0.03 ARG 321 -0.16 THR 306

MET 81 0.04 ILE 322 -0.17 THR 306

MET 81 0.04 PHE 323 -0.14 THR 306

MET 81 0.04 PHE 324 -0.13 THR 306

MET 81 0.04 PRO 325 -0.14 THR 306

MET 81 0.05 VAL 326 -0.13 ILE 321

MET 81 0.04 VAL 327 -0.11 ILE 321

MET 81 0.04 PHE 328 -0.10 ILE 302

MET 81 0.05 SER 329 -0.12 LEU 324

MET 81 0.05 PHE 330 -0.11 LEU 324

MET 81 0.05 PHE 331 -0.10 LEU 324

MET 81 0.05 ASN 332 -0.10 ALA 328

MET 81 0.05 ILE 333 -0.10 LEU 332

MET 81 0.06 VAL 334 -0.09 LEU 324

MET 81 0.06 TYR 335 -0.08 LEU 324

MET 81 0.05 TRP 336 -0.08 LEU 332

MET 81 0.06 LEU 337 -0.08 LEU 332

MET 81 0.07 TYR 338 -0.07 LEU 324

MET 81 0.06 TYR 339 -0.07 ASN 346

VAL 199 0.06 VAL 340 -0.07 ASP 24

GLY 32 0.12 ASP 10 -0.42 ARG 71

GLY 32 0.17 ASN 11 -0.37 ARG 71

GLY 32 0.12 THR 12 -0.44 ARG 71

GLY 32 0.08 THR 13 -0.53 GLY 22

GLY 203 0.09 VAL 14 -0.42 GLY 22

TYR 159 0.10 PHE 15 -0.41 GLY 25

TYR 159 0.07 THR 16 -0.57 GLY 22

GLY 203 0.08 ARG 17 -0.51 GLY 22

LEU 86 0.11 ILE 18 -0.50 GLY 25

MET 90 0.11 LEU 19 -0.44 GLY 22

LEU 127 0.06 ASP 20 -0.51 GLY 22

LEU 127 0.09 ARG 21 -0.56 GLY 25

LEU 127 0.10 LEU 22 -0.60 GLY 25

LEU 127 0.04 LEU 23 -0.54 THR 28

ASP 72 0.05 ASP 24 -0.68 VAL 29

PRO 32 0.05 GLY 25 -0.89 THR 28

PRO 32 0.06 TYR 26 -0.80 THR 28

PRO 32 0.09 ASP 27 -0.56 LEU 31

THR 125 0.01 ASN 28 -0.30 ILE 94

GLY 25 0.05 ARG 29 -0.37 ASP 27

GLY 25 0.04 LEU 30 -0.50 LEU 96

THR 125 0.04 ARG 31 -0.41 LEU 96

ASP 27 0.09 PRO 32 -0.36 LEU 96

ASP 27 0.06 GLY 33 -0.44 ILE 93

GLY 25 0.10 LEU 34 -0.51 ILE 93

GLY 25 0.19 GLY 35 -0.70 ILE 93

ARG 37 0.09 GLU 36 -0.52 ILE 93

GLU 36 0.09 ARG 37 -0.36 ILE 93

GLY 35 0.05 VAL 38 -0.27 VAL 95

VAL 198 0.04 THR 39 -0.26 VAL 95

VAL 198 0.05 GLU 40 -0.19 ILE 93

VAL 198 0.06 VAL 41 -0.17 ASP 10

THR 126 0.08 LYS 42 -0.16 ASP 10

THR 126 0.08 THR 43 -0.14 ASP 10

THR 126 0.10 ASP 44 -0.13 ASP 10

MET 81 0.08 ILE 45 -0.11 ASP 10

MET 81 0.10 PHE 46 -0.10 GLY 25

MET 81 0.08 VAL 47 -0.09 GLY 22

MET 81 0.09 THR 48 -0.10 GLY 22

MET 81 0.07 SER 49 -0.10 THR 125

VAL 53 0.08 PHE 50 -0.10 THR 125

VAL 53 0.09 GLY 51 -0.11 THR 125

VAL 53 0.10 PRO 52 -0.10 THR 125

VAL 53 0.10 VAL 53 -0.10 THR 125

ASN 66 0.11 SER 54 -0.10 THR 125

ASN 66 0.11 ASP 55 -0.08 THR 125

ASN 66 0.14 HIS 56 -0.12 SER 276

ASN 66 0.14 ASP 57 -0.10 ILE 124

PRO 64 0.13 MET 58 -0.09 ILE 124

PRO 64 0.10 GLU 59 -0.10 ILE 124

MET 49 0.09 TYR 60 -0.11 THR 125

MET 49 0.08 THR 61 -0.13 THR 125

MET 49 0.07 ILE 62 -0.12 THR 125

MET 81 0.07 ASP 63 -0.12 THR 125

MET 81 0.07 VAL 64 -0.10 THR 125

MET 81 0.08 PHE 65 -0.11 GLY 22

MET 81 0.07 PHE 66 -0.12 ASP 10

THR 126 0.08 ARG 67 -0.14 GLY 25

THR 126 0.08 GLN 68 -0.16 ASP 10

THR 126 0.12 SER 69 -0.19 ILE 93

GLU 73 0.08 TRP 70 -0.24 ILE 93

GLU 73 0.14 LYS 71 -0.30 ILE 93

GLU 73 0.10 ASP 72 -0.41 GLY 25

LYS 71 0.14 GLU 73 -0.66 GLY 25

ASP 72 0.09 ARG 74 -0.82 GLY 25

LEU 127 0.10 LEU 75 -0.62 GLY 25

LEU 127 0.10 LYS 76 -0.63 GLY 25

ARG 173 0.09 PHE 77 -0.57 GLY 25

ARG 173 0.09 LYS 78 -0.50 GLY 25

GLY 203 0.10 GLY 79 -0.43 GLY 25

GLY 203 0.13 PRO 80 -0.37 GLY 25

VAL 83 0.15 MET 81 -0.36 GLY 25

MET 81 0.13 THR 82 -0.39 GLY 25

MET 81 0.15 VAL 83 -0.37 GLY 25

MET 81 0.11 LEU 84 -0.37 GLY 25

ILE 18 0.10 ARG 85 -0.32 GLY 25

ILE 18 0.11 LEU 86 -0.31 GLY 25

ILE 18 0.10 ASN 87 -0.26 GLY 25

ILE 18 0.08 ASN 88 -0.26 ALA 91

LEU 19 0.08 LEU 89 -0.25 LEU 35

LEU 19 0.11 MET 90 -0.30 THR 28

LEU 19 0.10 ALA 91 -0.26 ASN 88

LEU 19 0.08 SER 92 -0.31 ASN 101

LEU 19 0.06 LYS 93 -0.33 LEU 35

THR 125 0.04 ILE 94 -0.30 LEU 35

THR 125 0.05 TRP 95 -0.30 LEU 96

THR 125 0.06 THR 96 -0.22 ASN 101

THR 125 0.07 PRO 97 -0.18 ASP 10

THR 125 0.10 ASP 98 -0.17 ASP 10

ILE 30 0.05 THR 99 -0.14 ASP 10

ILE 30 0.06 PHE 100 -0.13 ASP 10

ILE 30 0.06 PHE 101 -0.12 ASP 10

ILE 30 0.08 HIS 102 -0.11 ASP 10

ILE 30 0.07 ASN 103 -0.10 ASP 10

ILE 30 0.06 GLY 104 -0.10 ASP 10

THR 146 0.09 LYS 105 -0.09 ILE 124

LYS 118 0.08 LYS 106 -0.11 ILE 124

LYS 118 0.06 SER 107 -0.14 ILE 124

LYS 118 0.05 VAL 108 -0.11 THR 125

MET 81 0.05 ALA 109 -0.14 THR 126

MET 81 0.05 HIS 110 -0.13 ASN 101

MET 81 0.04 ASN 111 -0.15 ASN 101

VAL 16 0.04 MET 112 -0.13 ASN 101

VAL 16 0.05 THR 113 -0.15 GLY 25

ASP 95 0.04 MET 114 -0.17 ASN 101

ILE 18 0.04 PRO 115 -0.19 ASN 101

ILE 18 0.06 ASN 116 -0.17 ASN 101

LEU 118 0.12 LYS 117 -0.19 ASN 101

LYS 117 0.12 LEU 118 -0.21 GLY 25

ILE 18 0.10 LEU 119 -0.27 GLY 25

ILE 18 0.10 ARG 120 -0.31 GLY 25

LEU 128 0.10 ILE 121 -0.39 GLY 25

ARG 173 0.10 THR 122 -0.40 GLY 25

ARG 173 0.10 GLU 123 -0.46 GLY 25

ARG 173 0.12 ASP 124 -0.48 GLY 25

THR 172 0.11 GLY 125 -0.51 GLY 25

THR 172 0.13 THR 126 -0.39 GLY 25

GLY 125 0.10 LEU 127 -0.30 GLY 25

THR 126 0.13 LEU 128 -0.24 GLY 25

ILE 18 0.08 TYR 129 -0.20 GLY 25

MET 81 0.08 THR 130 -0.16 GLY 25

MET 81 0.07 MET 131 -0.16 ASN 101

MET 81 0.07 ARG 132 -0.13 ASN 101

MET 81 0.06 LEU 133 -0.17 THR 125

LYS 118 0.07 THR 134 -0.14 THR 125

LYS 118 0.07 VAL 135 -0.15 THR 125

ASP 148 0.08 ARG 136 -0.14 ILE 124

THR 73 0.08 ALA 137 -0.11 THR 125

THR 73 0.10 GLU 138 -0.08 ILE 124

PRO 64 0.09 CYS 139 -0.08 ASP 10

PRO 64 0.11 PRO 140 -0.07 ASP 10

PRO 64 0.12 MET 141 -0.06 ASP 10

ARG 194 0.12 HIS 142 -0.06 ASP 10

TYR 199 0.13 LEU 143 -0.09 THR 284

ASP 145 0.14 GLU 144 -0.05 ALA 291

GLU 144 0.14 ASP 145 -0.10 ALA 285

SER 286 0.11 PHE 146 -0.09 ALA 285

SER 286 0.10 PRO 147 -0.07 THR 125

SER 286 0.09 MET 148 -0.08 TYR 344

THR 271 0.09 ASP 149 -0.06 ASP 10

ARG 194 0.08 ALA 150 -0.07 ASP 10

PRO 64 0.08 HIS 151 -0.07 ASP 10

PRO 64 0.08 ALA 152 -0.07 ASP 10

VAL 53 0.08 CYS 153 -0.08 ASP 10

VAL 53 0.07 PRO 154 -0.09 ASP 10

MET 81 0.06 LEU 155 -0.10 ASP 10

ILE 30 0.06 LYS 156 -0.11 ASP 10

ILE 30 0.06 PHE 157 -0.12 ASP 10

VAL 27 0.07 GLY 158 -0.14 ASP 10

VAL 27 0.09 SER 159 -0.16 ASP 10

VAL 27 0.12 TYR 160 -0.16 ASP 10

VAL 27 0.17 ALA 161 -0.18 ASP 10

VAL 27 0.16 TYR 162 -0.18 ASP 10

VAL 27 0.16 THR 163 -0.18 ASP 10

ASP 26 0.12 ARG 164 -0.17 ASP 10

ASP 26 0.15 ALA 165 -0.19 ASP 10

GLY 25 0.12 GLU 166 -0.21 VAL 95

ASP 26 0.05 VAL 167 -0.18 ASP 10

ASN 346 0.04 VAL 168 -0.17 ASP 10

VAL 198 0.05 TYR 169 -0.15 ASP 10

VAL 198 0.06 GLU 170 -0.14 ASP 10

THR 126 0.09 TRP 171 -0.13 ASP 10

THR 126 0.13 THR 172 -0.14 ASP 10

ASP 124 0.12 ARG 173 -0.13 ASP 10

ASP 124 0.10 GLU 174 -0.12 ASP 10

ASP 124 0.08 PRO 175 -0.12 ASP 10

GLY 195 0.09 ALA 176 -0.11 ASP 10

ASP 124 0.10 ARG 177 -0.11 ASP 10

THR 126 0.10 SER 178 -0.12 ASP 10

THR 126 0.09 VAL 179 -0.11 ASP 10

VAL 181 0.11 VAL 180 -0.10 GLY 25

VAL 180 0.11 VAL 181 -0.09 GLY 22

MET 81 0.10 ALA 182 -0.09 GLY 22

MET 81 0.10 GLU 183 -0.10 ASN 346

MET 81 0.09 ASP 184 -0.10 ASN 346

MET 81 0.08 GLY 185 -0.09 GLY 22

VAL 53 0.08 SER 186 -0.09 ASN 346

VAL 53 0.09 ARG 187 -0.09 THR 125

VAL 53 0.09 LEU 188 -0.09 THR 125

VAL 53 0.09 ASN 189 -0.10 LEU 345

THR 271 0.10 GLN 190 -0.10 LEU 345

THR 271 0.08 TYR 191 -0.10 ARG 347

VAL 53 0.08 ASP 192 -0.13 ARG 347

VAL 53 0.07 LEU 193 -0.10 ARG 347

MET 81 0.07 LEU 194 -0.12 ARG 347

ALA 176 0.09 GLY 195 -0.08 ARG 347

ALA 176 0.08 GLN 196 -0.09 ASP 10

ASP 124 0.08 THR 197 -0.09 ASP 10

THR 126 0.08 VAL 198 -0.10 ASP 10

ASP 124 0.06 ASP 199 -0.11 ASP 10

ASN 346 0.06 SER 200 -0.12 ASP 10

ASN 346 0.08 GLY 201 -0.13 ASP 10

ASP 26 0.10 ILE 202 -0.14 ASP 10

ASP 26 0.10 VAL 203 -0.14 ASP 10

ASP 26 0.13 GLN 204 -0.16 SER 186

LYS 94 0.14 SER 205 -0.18 SER 186

LYS 94 0.20 SER 206 -0.25 SER 186

VAL 95 0.22 THR 207 -0.20 LYS 184

VAL 95 0.19 GLY 208 -0.20 SER 186

ASP 26 0.15 GLU 209 -0.16 SER 186

VAL 27 0.12 TYR 210 -0.16 ASP 10

VAL 27 0.09 VAL 211 -0.15 ASP 10

VAL 27 0.07 VAL 212 -0.13 ASP 10

ILE 30 0.05 MET 213 -0.12 ASP 10

ILE 30 0.05 THR 214 -0.11 ASP 10

MET 81 0.06 THR 215 -0.10 ASP 10

PHE 217 0.12 HIS 216 -0.09 ASP 10

HIS 216 0.12 PHE 217 -0.08 ASP 10

HIS 216 0.07 HIS 218 -0.08 ASP 10

VAL 53 0.07 LEU 219 -0.08 ARG 347

THR 271 0.07 LYS 220 -0.13 ARG 347

THR 271 0.08 ARG 221 -0.10 ARG 347

THR 271 0.08 LYS 222 -0.14 LEU 345

SER 286 0.08 ILE 223 -0.17 LEU 345

SER 286 0.08 GLY 224 -0.15 LEU 345

SER 286 0.09 TYR 225 -0.11 LEU 345

THR 271 0.09 PHE 226 -0.08 LEU 345

THR 271 0.07 VAL 227 -0.10 LEU 345

THR 271 0.07 ILE 228 -0.08 LEU 345

THR 271 0.08 GLN 229 -0.08 THR 125

THR 271 0.09 THR 230 -0.07 ILE 124

THR 271 0.08 TYR 231 -0.06 THR 125

THR 271 0.06 LEU 232 -0.07 TRP 341

HIS 267 0.07 PRO 233 -0.07 ILE 124

HIS 267 0.07 CYS 234 -0.06 ILE 124

HIS 267 0.06 ILE 235 -0.07 ASN 337

HIS 267 0.06 MET 236 -0.07 LEU 297

HIS 267 0.07 THR 237 -0.06 ILE 124

HIS 267 0.07 VAL 238 -0.06 ILE 124

HIS 267 0.05 ILE 239 -0.08 LEU 297

HIS 267 0.05 LEU 240 -0.07 TYR 309

HIS 267 0.06 SER 241 -0.06 SER 313

HIS 267 0.05 GLN 242 -0.07 SER 313

HIS 267 0.05 VAL 243 -0.10 ALA 300

HIS 267 0.05 SER 244 -0.07 SER 313

HIS 267 0.04 PHE 245 -0.07 SER 313

HIS 267 0.04 TRP 246 -0.09 SER 313

HIS 267 0.04 LEU 247 -0.09 SER 313

LEU 253 0.03 ASN 248 -0.09 SER 313

ALA 246 0.05 ARG 249 -0.08 SER 313

ALA 246 0.05 GLU 250 -0.09 ASN 258

ALA 246 0.04 SER 251 -0.09 ASN 258

ALA 246 0.07 VAL 252 -0.13 ILE 257

ALA 249 0.08 PRO 253 -0.09 ILE 257

ALA 252 0.05 ALA 254 -0.11 SER 247

LEU 253 0.05 ARG 255 -0.06 SER 247

LEU 253 0.07 THR 256 -0.08 SER 254

LEU 253 0.07 VAL 257 -0.07 ALA 248

LEU 253 0.05 PHE 258 -0.06 ILE 124

LEU 253 0.06 GLY 259 -0.06 LEU 250

LEU 253 0.07 VAL 260 -0.08 LEU 250

THR 263 0.07 THR 261 -0.07 ILE 124

HIS 267 0.08 THR 262 -0.06 ILE 124

HIS 267 0.09 VAL 263 -0.07 ILE 124

THR 263 0.11 LEU 264 -0.07 ILE 124

HIS 267 0.10 THR 265 -0.07 ILE 124

HIS 267 0.10 MET 266 -0.07 ILE 124

HIS 267 0.13 THR 267 -0.08 ILE 124

HIS 267 0.14 THR 268 -0.09 ILE 271

HIS 267 0.11 LEU 269 -0.09 ALA 273

LEU 268 0.12 SER 270 -0.10 ARG 274

ILE 282 0.13 ILE 271 -0.09 THR 268

THR 271 0.12 SER 272 -0.08 ILE 124

THR 271 0.12 ALA 273 -0.10 SER 270

THR 271 0.14 ARG 274 -0.10 SER 270

THR 271 0.17 ASN 275 -0.10 HIS 56

THR 271 0.14 SER 276 -0.12 HIS 56

THR 271 0.14 LEU 277 -0.10 HIS 56

SER 286 0.17 PRO 278 -0.09 ILE 124

SER 286 0.19 LYS 279 -0.08 ILE 124

GLN 200 0.14 VAL 280 -0.06 ILE 124

GLN 200 0.20 ALA 281 -0.07 LEU 355

GLY 234 0.16 TYR 282 -0.06 TYR 356

TYR 235 0.15 ALA 283 -0.06 ALA 291

TYR 344 0.11 THR 284 -0.09 LEU 143

TYR 344 0.11 ALA 285 -0.10 ASP 145

THR 271 0.11 MET 286 -0.07 PHE 146

ILE 238 0.14 ASP 287 -0.10 ALA 291

ILE 238 0.15 TRP 288 -0.06 VAL 292

ALA 283 0.10 PHE 289 -0.06 THR 125

LEU 268 0.11 ILE 290 -0.07 ASP 287

PRO 243 0.13 ALA 291 -0.10 ASP 287

PHE 336 0.10 VAL 292 -0.06 ILE 124

LEU 268 0.09 CYS 293 -0.06 ILE 124

LEU 268 0.10 TYR 294 -0.06 ILE 124

LEU 246 0.11 ALA 295 -0.06 ILE 124

LEU 268 0.08 PHE 296 -0.06 SER 313

HIS 267 0.08 VAL 297 -0.06 ILE 124

LEU 235 0.07 PHE 298 -0.06 ILE 124

LEU 332 0.08 SER 299 -0.06 VAL 352

HIS 267 0.06 ALA 300 -0.06 ILE 124

LEU 268 0.08 LEU 301 -0.06 CYS 344

VAL 238 0.08 ILE 302 -0.07 CYS 344

TRP 241 0.06 GLU 303 -0.06 LEU 348

ILE 242 0.06 PHE 304 -0.06 CYS 344

ILE 257 0.09 ALA 305 -0.08 CYS 344

ILE 257 0.08 THR 306 -0.08 CYS 344

ILE 242 0.07 VAL 307 -0.07 CYS 344

ALA 261 0.09 ASN 308 -0.07 PRO 340

ASN 258 0.12 TYR 309 -0.08 PRO 340

ASP 260 0.09 PHE 310 -0.07 CYS 344

ASP 260 0.09 THR 311 -0.06 CYS 344

ASP 260 0.10 LYS 312 -0.06 PRO 340

SER 322 0.10 SER 313 -0.07 THR 341

SER 322 0.08 GLN 314 -0.07 CYS 344

SER 322 0.07 PRO 315 -0.06 CYS 344

SER 322 0.06 ALA 316 -0.06 LEU 348

PRO 325 0.07 ARG 317 -0.06 LEU 348

ASN 243 0.06 ALA 318 -0.06 CYS 344

ILE 242 0.05 ALA 319 -0.07 SER 313

SER 322 0.05 LYS 320 -0.06 SER 313

ILE 242 0.06 ILE 321 -0.06 SER 313

ILE 242 0.05 ASP 322 -0.07 SER 313

TRP 241 0.04 ARG 323 -0.08 SER 313

TRP 241 0.05 LEU 324 -0.07 SER 313

GLU 303 0.06 SER 325 -0.06 SER 313

HIS 267 0.05 ARG 326 -0.08 SER 313

HIS 267 0.05 ILE 327 -0.08 SER 313

SER 299 0.06 ALA 328 -0.07 SER 313

SER 299 0.07 PHE 329 -0.07 SER 313

LEU 268 0.05 PRO 330 -0.09 LEU 301

SER 299 0.06 LEU 331 -0.08 LEU 301

GLY 334 0.08 LEU 332 -0.06 SER 313

SER 299 0.07 PHE 333 -0.07 LEU 297

LEU 332 0.08 GLY 334 -0.11 LEU 297

ILE 242 0.09 ILE 335 -0.09 LEU 297

ILE 242 0.11 PHE 336 -0.07 LEU 297

ILE 238 0.08 ASN 337 -0.09 LEU 297

GLY 234 0.09 LEU 338 -0.09 VAL 290

ILE 238 0.11 VAL 339 -0.08 TYR 277

ILE 238 0.12 TYR 340 -0.07 ILE 223

ALA 285 0.10 TRP 341 -0.10 GLY 224

GLY 234 0.11 ALA 342 -0.11 TYR 277

GLY 234 0.14 THR 343 -0.09 ILE 223

GLY 234 0.13 TYR 344 -0.12 ILE 223

ARG 194 0.11 LEU 345 -0.17 ILE 223

ARG 194 0.13 ASN 346 -0.13 ILE 223

ARG 194 0.16 ARG 347 -0.13 LYS 220

GLY 35 0.19 GLY 25 -0.82 ARG 74

ARG 97 0.21 ASP 26 -0.61 ARG 74

ARG 97 0.27 VAL 27 -0.59 GLY 25

ARG 97 0.15 THR 28 -0.89 GLY 25

ARG 97 0.17 VAL 29 -0.88 GLY 25

ARG 132 0.23 ILE 30 -0.67 GLY 25

LEU 98 0.20 LEU 31 -0.68 GLY 25

LEU 98 0.11 ASN 32 -0.83 GLY 25

ARG 132 0.17 ASN 33 -0.68 GLY 25

LEU 87 0.15 LEU 34 -0.67 GLY 25

LYS 105 0.09 LEU 35 -0.66 GLY 25

LEU 87 0.07 GLU 36 -0.64 GLY 25

LEU 87 0.05 GLY 37 -0.56 ASP 17

TRP 107 0.05 TYR 38 -0.50 GLY 25

TYR 356 0.03 ASP 39 -0.42 ASP 17

TYR 356 0.03 ASN 40 -0.38 GLY 25

LYS 13 0.08 LYS 41 -0.32 GLY 25

MET 9 0.05 LEU 42 -0.34 ASP 10

TYR 356 0.05 ARG 43 -0.33 GLY 25

TYR 356 0.05 PRO 44 -0.36 GLY 25

TYR 356 0.06 ASP 45 -0.34 GLY 25

MET 9 0.08 ILE 46 -0.32 GLY 25

ASN 8 0.16 GLY 47 -0.32 ASP 10

GLU 177 0.08 VAL 48 -0.31 GLY 25

TYR 356 0.08 LYS 49 -0.28 GLY 25

TYR 356 0.08 PRO 50 -0.27 GLY 25

TYR 356 0.07 THR 51 -0.28 GLY 25

TYR 356 0.07 LEU 52 -0.25 GLY 25

TYR 83 0.07 ILE 53 -0.25 ASP 27

TRP 82 0.12 HIS 54 -0.23 ASP 27

ARG 138 0.09 THR 55 -0.21 ASP 27

ARG 138 0.11 ASP 56 -0.19 SER 206

LYS 94 0.10 MET 57 -0.16 ASP 27

LYS 94 0.11 TYR 58 -0.13 ASP 27

LYS 94 0.10 VAL 59 -0.12 ASP 10

LYS 94 0.10 ASN 60 -0.11 ASP 10

LYS 94 0.09 SER 61 -0.10 ASP 10

ARG 347 0.09 ILE 62 -0.09 ASP 27

PRO 140 0.11 GLY 63 -0.09 ASP 27

ASP 57 0.14 PRO 64 -0.08 ASP 27

ASP 57 0.11 VAL 65 -0.09 ASP 27

ASP 57 0.14 ASN 66 -0.09 SER 286

LEU 272 0.12 ALA 67 -0.09 ASP 27

GLU 52 0.15 ILE 68 -0.12 LYS 285

MET 49 0.19 ASN 69 -0.09 ASP 27

MET 49 0.15 MET 70 -0.09 ASP 27

ASP 57 0.11 GLU 71 -0.09 ASP 27

ASP 57 0.12 TYR 72 -0.09 ASP 27

GLU 138 0.10 THR 73 -0.10 ASP 27

PRO 140 0.09 ILE 74 -0.10 ASP 27

ILE 30 0.08 ASP 75 -0.11 ASP 10

ILE 30 0.09 ILE 76 -0.12 ASP 27

ILE 30 0.11 PHE 77 -0.14 ASP 27

ALA 79 0.20 PHE 78 -0.17 ASP 27

PHE 78 0.20 ALA 79 -0.21 ASP 27

PHE 78 0.10 GLN 80 -0.24 ASP 27

SER 187 0.10 THR 81 -0.28 ASP 27

HIS 54 0.12 TRP 82 -0.29 ASP 27

HIS 54 0.10 TYR 83 -0.33 GLY 25

LEU 34 0.07 ASP 84 -0.38 GLY 25

SER 187 0.07 ARG 85 -0.40 GLY 25

SER 187 0.05 ARG 86 -0.46 GLY 25

LEU 34 0.15 LEU 87 -0.49 GLY 25

SER 187 0.10 LYS 88 -0.45 GLY 25

SER 206 0.11 PHE 89 -0.51 GLY 25

SER 206 0.12 ASN 90 -0.48 GLY 25

GLY 208 0.13 SER 91 -0.48 GLY 25

GLY 208 0.16 THR 92 -0.53 GLY 35

GLY 208 0.19 ILE 93 -0.70 GLY 35

SER 206 0.20 LYS 94 -0.56 GLY 35

THR 207 0.22 VAL 95 -0.51 GLY 35

ARG 132 0.22 LEU 96 -0.50 LEU 30

VAL 27 0.27 ARG 97 -0.27 ASP 27

VAL 27 0.23 LEU 98 -0.32 ASP 27

LEU 31 0.16 ASN 99 -0.23 ASP 27

LEU 31 0.14 SER 100 -0.23 ASP 27

LEU 31 0.14 ASN 101 -0.31 SER 92

LEU 31 0.18 MET 102 -0.43 ASP 27

LEU 31 0.14 VAL 103 -0.31 ASP 27

LEU 31 0.10 GLY 104 -0.29 ASP 27

ASN 33 0.10 LYS 105 -0.37 ASP 27

LEU 35 0.08 ILE 106 -0.43 ASP 27

LEU 34 0.07 TRP 107 -0.35 ASP 27

LEU 34 0.07 ILE 108 -0.31 ASP 27

LEU 34 0.06 PRO 109 -0.26 ASP 27

THR 15 0.05 ASP 110 -0.22 ASP 27

ILE 30 0.05 THR 111 -0.20 ASP 27

THR 15 0.05 PHE 112 -0.17 ASP 27

ARG 347 0.06 PHE 113 -0.15 ASP 27

ALA 45 0.09 ARG 114 -0.14 ASP 27

GLU 168 0.07 ASN 115 -0.12 ASP 27

GLU 138 0.06 SER 116 -0.12 ASP 27

LYS 106 0.08 LYS 117 -0.11 ASP 27

LYS 106 0.08 LYS 118 -0.11 ASP 27

LYS 106 0.08 ALA 119 -0.12 ASP 27

LYS 106 0.06 ASP 120 -0.12 ASP 27

ILE 30 0.07 ALA 121 -0.13 ASP 27

ILE 30 0.07 HIS 122 -0.12 ASP 10

ILE 30 0.06 TRP 123 -0.12 ASP 10

LEU 19 0.06 ILE 124 -0.14 ARG 136

ASP 98 0.10 THR 125 -0.17 LEU 133

ILE 30 0.06 THR 126 -0.16 LYS 117

ILE 30 0.07 PRO 127 -0.15 ASP 10

ILE 30 0.09 ASN 128 -0.15 ASP 10

ILE 30 0.11 ARG 129 -0.20 ASP 27

ILE 30 0.14 MET 130 -0.24 ASP 27

ILE 30 0.18 LEU 131 -0.31 ASP 27

ILE 30 0.23 ARG 132 -0.30 ASP 27

ILE 30 0.15 ILE 133 -0.43 ASP 27

SER 206 0.12 TRP 134 -0.38 GLY 35

SER 206 0.11 ASN 135 -0.40 GLY 35

SER 186 0.12 ASP 136 -0.37 GLY 25

SER 187 0.11 GLY 137 -0.39 GLY 25

SER 187 0.13 ARG 138 -0.33 GLY 25

ASN 33 0.10 VAL 139 -0.35 ASP 27

THR 142 0.13 LEU 140 -0.30 ASP 27

THR 142 0.16 TYR 141 -0.28 ASP 27

TYR 141 0.16 THR 142 -0.20 ASP 27

ILE 30 0.11 LEU 143 -0.18 ASP 27

ILE 30 0.10 ARG 144 -0.14 ASP 27

ILE 30 0.08 LEU 145 -0.13 ASP 27

LYS 105 0.09 THR 146 -0.11 ASP 27

LYS 105 0.08 ILE 147 -0.11 ASP 27

GLU 138 0.08 ASP 148 -0.10 ASP 27

ASP 57 0.08 ALA 149 -0.11 ASP 27

ASP 48 0.10 GLU 150 -0.10 ASP 27

ASP 57 0.10 CYS 151 -0.09 ASP 27

GLU 182 0.15 GLN 152 -0.09 ASP 27

GLU 182 0.16 LEU 153 -0.08 ASP 27

GLU 182 0.20 GLN 154 -0.08 ASP 27

SER 187 0.18 LEU 155 -0.08 ASP 27

SER 187 0.19 HIS 156 -0.07 ASP 27

SER 187 0.16 ASN 157 -0.07 ASP 27

SER 187 0.14 PHE 158 -0.08 ASP 27

LEU 272 0.12 PRO 159 -0.08 ASP 27

SER 187 0.12 MET 160 -0.11 LEU 357

SER 187 0.14 ASP 161 -0.08 ASP 27

SER 187 0.13 GLU 162 -0.09 ASP 27

SER 187 0.13 HIS 163 -0.09 ASP 27

LYS 180 0.12 SER 164 -0.10 ASP 27

LYS 180 0.12 CYS 165 -0.11 ASP 27

LYS 180 0.11 PRO 166 -0.12 ASP 27

ARG 347 0.08 LEU 167 -0.13 ASP 27

PHE 169 0.09 GLU 168 -0.13 ASP 27

GLU 168 0.09 PHE 169 -0.16 ASP 27

GLY 177 0.07 SER 170 -0.18 ASP 27

THR 15 0.07 SER 171 -0.21 ASP 27

THR 15 0.08 TYR 172 -0.20 GLY 25

THR 15 0.11 GLY 173 -0.22 GLY 25

VAL 12 0.10 TYR 174 -0.24 GLY 25

VAL 12 0.10 PRO 175 -0.22 GLY 25

TYR 356 0.09 ARG 176 -0.21 GLY 25

ASN 8 0.11 GLU 177 -0.23 GLY 25

ASN 8 0.09 GLU 178 -0.25 GLY 25

TYR 356 0.07 ILE 179 -0.25 GLY 25

MET 223 0.08 VAL 180 -0.23 GLY 25

MET 223 0.11 TYR 181 -0.21 ASP 27

LYS 180 0.08 GLN 182 -0.20 ASP 27

ASP 136 0.08 TRP 183 -0.18 ASP 27

ASP 136 0.11 LYS 184 -0.21 SER 206

ASP 136 0.12 ARG 185 -0.20 SER 206

LYS 94 0.13 SER 186 -0.25 SER 206

ARG 138 0.13 SER 187 -0.19 SER 206

LYS 94 0.11 VAL 188 -0.15 SER 206

LYS 94 0.13 GLU 189 -0.13 SER 205

LYS 94 0.11 VAL 190 -0.11 ASP 10

LYS 94 0.11 GLY 191 -0.11 ASP 10

ARG 347 0.13 ASP 192 -0.10 ASP 10

ARG 347 0.14 THR 193 -0.09 ASP 10

ARG 347 0.16 ARG 194 -0.09 ASP 10

ARG 347 0.12 SER 195 -0.09 ASP 10

ARG 347 0.11 TRP 196 -0.09 ASP 10

PRO 64 0.13 ARG 197 -0.08 ILE 124

ARG 347 0.11 LEU 198 -0.08 ASP 27

LEU 143 0.13 TYR 199 -0.07 ASP 27

ALA 281 0.20 GLN 200 -0.08 LEU 355

ALA 281 0.15 PHE 201 -0.08 ASP 27

ARG 347 0.14 SER 202 -0.09 LEU 357

ARG 347 0.13 PHE 203 -0.09 ASP 27

ARG 347 0.13 VAL 204 -0.08 ASP 27

ARG 347 0.12 GLY 205 -0.10 ASP 27

ARG 347 0.11 LEU 206 -0.11 ASP 27

ARG 347 0.10 ARG 207 -0.12 ASP 27

LYS 180 0.10 ASN 208 -0.14 ASP 27

LYS 180 0.11 THR 209 -0.15 ASP 27

LYS 180 0.11 THR 210 -0.16 GLY 25

LYS 180 0.12 GLU 211 -0.16 GLY 25

GLY 177 0.12 VAL 212 -0.17 GLY 25

GLY 177 0.16 VAL 213 -0.17 GLY 25

GLY 177 0.13 LYS 214 -0.17 GLY 25

THR 176 0.12 THR 215 -0.17 GLY 25

PRO 78 0.12 THR 216 -0.18 GLY 25

PRO 78 0.13 SER 217 -0.19 GLY 25

PRO 78 0.13 GLY 218 -0.20 GLY 25

LEU 357 0.10 ASP 219 -0.19 GLY 25

GLY 177 0.10 TYR 220 -0.19 GLY 25

GLY 177 0.09 VAL 221 -0.19 GLY 25

GLY 177 0.11 VAL 222 -0.17 ASP 27

TYR 181 0.11 MET 223 -0.15 ASP 27

LYS 180 0.10 SER 224 -0.14 ASP 27

LYS 180 0.10 VAL 225 -0.14 ASP 27

LYS 180 0.11 TYR 226 -0.12 ASP 27

ARG 347 0.10 PHE 227 -0.11 ASP 27

ARG 347 0.11 ASP 228 -0.10 ASP 27

ARG 347 0.12 LEU 229 -0.10 ASP 27

ARG 347 0.13 SER 230 -0.09 ASP 27

ARG 232 0.17 ARG 231 -0.10 LEU 357

ARG 231 0.17 ARG 232 -0.11 LEU 355

THR 343 0.12 MET 233 -0.12 LEU 355

TYR 282 0.16 GLY 234 -0.11 LEU 355

TYR 282 0.15 TYR 235 -0.07 ILE 124

THR 271 0.12 PHE 236 -0.07 ASP 27

THR 343 0.12 THR 237 -0.09 LEU 355

TRP 288 0.15 ILE 238 -0.08 LEU 355

ASP 287 0.13 GLN 239 -0.08 ILE 124

LEU 268 0.13 THR 240 -0.07 ASP 27

LEU 268 0.10 TYR 241 -0.07 ASP 27

ALA 291 0.13 ILE 242 -0.07 TRP 351

ALA 291 0.13 PRO 243 -0.07 ILE 124

LEU 268 0.10 CYS 244 -0.07 ASP 27

ALA 291 0.10 THR 245 -0.06 ASP 27

ALA 291 0.11 LEU 246 -0.06 VAL 260

ALA 295 0.09 ILE 247 -0.07 VAL 260

PHE 336 0.08 VAL 248 -0.06 ASP 27

PHE 336 0.09 VAL 249 -0.07 VAL 260

ALA 295 0.10 LEU 250 -0.08 VAL 260

LEU 235 0.09 SER 251 -0.07 ALA 248

PHE 336 0.08 TRP 252 -0.07 PRO 340

VAL 238 0.07 VAL 253 -0.08 VAL 252

VAL 238 0.08 SER 254 -0.08 VAL 252

TRP 241 0.08 PHE 255 -0.08 VAL 252

TRP 241 0.07 TRP 256 -0.09 VAL 252

ALA 305 0.09 ILE 257 -0.13 VAL 252

TYR 309 0.12 ASN 258 -0.10 VAL 252

TYR 309 0.11 LYS 259 -0.08 LYS 312

TYR 309 0.10 ASP 260 -0.09 LYS 312

TYR 309 0.10 ALA 261 -0.10 ALA 246

ILE 242 0.09 VAL 262 -0.09 ALA 246

ALA 249 0.09 PRO 263 -0.11 ALA 248

ALA 305 0.08 ALA 264 -0.14 ALA 248

ALA 305 0.08 ARG 265 -0.09 ALA 248

LEU 253 0.08 THR 266 -0.08 ALA 248

LEU 253 0.08 SER 267 -0.09 ALA 248

LEU 301 0.08 LEU 268 -0.09 ALA 248

LEU 235 0.09 GLY 269 -0.06 ALA 248

THR 257 0.09 ILE 270 -0.07 ASP 27

VAL 263 0.07 THR 271 -0.07 ASP 27

ALA 295 0.08 THR 272 -0.07 ASP 27

ILE 232 0.10 VAL 273 -0.07 ASP 27

ILE 264 0.12 LEU 274 -0.07 ASP 27

ILE 264 0.11 THR 275 -0.07 ASP 27

ILE 264 0.11 MET 276 -0.07 ASP 27

ILE 264 0.14 THR 277 -0.07 ASP 27

HIS 267 0.14 THR 278 -0.08 ASP 27

LEU 268 0.14 LEU 279 -0.08 ASP 27

LEU 268 0.16 SER 280 -0.07 ASP 27

LEU 268 0.22 THR 281 -0.08 ASP 27

LEU 268 0.17 ILE 282 -0.09 LYS 118

LEU 268 0.15 ALA 283 -0.08 ASP 27

THR 271 0.18 ARG 284 -0.08 ILE 68

THR 271 0.22 LYS 285 -0.12 ILE 68

LYS 279 0.19 SER 286 -0.10 ILE 68

LYS 279 0.17 LEU 287 -0.11 ILE 68

LEU 272 0.18 PRO 288 -0.09 ASP 27

LEU 272 0.22 LYS 289 -0.08 ASP 27

GLN 185 0.19 VAL 290 -0.08 ASP 27

ASN 217 0.26 SER 291 -0.08 ASP 27

GLY 219 0.21 TYR 292 -0.07 ASP 27

GLY 219 0.22 VAL 293 -0.07 ASP 27

ALA 295 0.16 THR 294 -0.07 ASP 27

GLY 219 0.17 ALA 295 -0.07 ASP 27

TYR 220 0.14 MET 296 -0.07 ASP 27

LEU 223 0.18 ASP 297 -0.08 ASP 27

LEU 223 0.19 LEU 298 -0.07 ASP 27

LEU 223 0.13 PHE 299 -0.07 ASP 27

LEU 268 0.13 VAL 300 -0.07 ASP 27

LEU 223 0.18 SER 301 -0.07 ASP 27

MET 227 0.14 VAL 302 -0.07 ASP 27

MET 227 0.11 CYS 303 -0.07 ASP 27

LEU 231 0.11 PHE 304 -0.07 ASP 27

LEU 231 0.12 ILE 305 -0.07 ASP 27

PRO 325 0.09 PHE 306 -0.06 ASP 27

ILE 234 0.09 VAL 307 -0.07 ASP 27

ILE 234 0.12 PHE 308 -0.07 ASP 27

ILE 234 0.11 SER 309 -0.06 ASP 27

ARG 321 0.08 ALA 310 -0.06 ALA 248

VAL 238 0.10 LEU 311 -0.06 ASP 27

VAL 238 0.14 VAL 312 -0.06 ASP 27

ARG 321 0.10 GLU 313 -0.06 ASP 27

TRP 241 0.09 TYR 314 -0.06 ALA 248

TRP 241 0.14 GLY 315 -0.06 ASP 27

TRP 241 0.10 THR 316 -0.06 ASP 27

ARG 318 0.07 LEU 317 -0.06 LYS 312

TYR 309 0.08 HIS 318 -0.06 LYS 312

ALA 314 0.10 TYR 319 -0.06 ASP 27

ALA 314 0.08 PHE 320 -0.06 ASP 27

SER 313 0.09 VAL 321 -0.07 LYS 312

SER 313 0.10 SER 322 -0.06 LYS 312

SER 313 0.08 SER 323 -0.06 ASP 27

SER 313 0.08 GLN 324 -0.06 LYS 312

SER 313 0.09 PRO 325 -0.07 LYS 312

SER 313 0.07 ALA 326 -0.06 LYS 312

ALA 311 0.06 ARG 327 -0.06 LYS 312

TYR 309 0.06 ALA 328 -0.07 LYS 312

TYR 309 0.07 ALA 329 -0.07 LYS 312

VAL 339 0.06 LYS 330 -0.07 LYS 312

ARG 318 0.07 MET 331 -0.06 LYS 312

ARG 321 0.06 ASP 332 -0.07 LYS 312

VAL 339 0.07 SER 333 -0.07 LYS 312

VAL 339 0.07 TYR 334 -0.06 LYS 312

ARG 321 0.08 ALA 335 -0.06 ALA 248

VAL 339 0.08 ARG 336 -0.07 VAL 252

VAL 339 0.08 ILE 337 -0.06 SER 313

ILE 322 0.08 PHE 338 -0.05 ALA 248

ILE 322 0.08 PHE 339 -0.05 ALA 248

VAL 339 0.08 PRO 340 -0.08 TYR 309

ILE 322 0.09 THR 341 -0.08 TYR 309

PRO 325 0.11 ALA 342 -0.05 ASP 27

PRO 325 0.09 PHE 343 -0.06 ASP 27

PRO 325 0.09 CYS 344 -0.08 TYR 309

PRO 325 0.11 LEU 345 -0.06 PHE 310

SER 329 0.12 PHE 346 -0.06 ASP 27

GLY 219 0.12 ASN 347 -0.06 ILE 302

GLY 219 0.12 LEU 348 -0.07 VAL 349

GLY 219 0.15 VAL 349 -0.07 LEU 348

GLY 219 0.16 TYR 350 -0.06 ASP 27

GLY 219 0.14 TRP 351 -0.08 THR 237

GLY 219 0.15 VAL 352 -0.08 GLY 234

GLY 219 0.19 SER 353 -0.07 ASP 27

GLY 219 0.19 TYR 354 -0.08 MET 233

SER 187 0.16 LEU 355 -0.12 MET 233

SER 187 0.18 TYR 356 -0.10 ARG 232

SER 187 0.21 LEU 357 -0.11 MET 160

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** ***

CA distance fluctuations for 2403120153442850967

--- normal mode 21 ---

Should you encounter any unexpected behaviour,
please let us know.

* *