Should you encounter any unexpected behaviour,
please let us know.

* 6x3x *

CA distance fluctuations for 2403121503062936047

--- normal mode 26 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
LEU 345 0.07 SER 7 -0.08 ASN 33

GLY 47 0.09 ASN 8 -0.07 GLY 37

LEU 345 0.07 MET 9 -0.08 GLY 37

LEU 345 0.06 SER 10 -0.12 GLY 37

LEU 345 0.07 LEU 11 -0.09 GLY 37

LEU 345 0.08 VAL 12 -0.08 GLY 37

LEU 345 0.07 LYS 13 -0.10 GLY 37

LEU 345 0.06 GLU 14 -0.10 GLY 37

LEU 345 0.07 THR 15 -0.09 ASP 10

LEU 345 0.07 VAL 16 -0.09 LYS 105

LEU 345 0.06 ASP 17 -0.10 LYS 105

LEU 345 0.06 ARG 18 -0.10 ASP 10

ASN 346 0.07 LEU 19 -0.11 ASP 10

LEU 345 0.06 LEU 20 -0.10 GLY 104

LEU 345 0.05 LYS 21 -0.10 GLY 104

ASN 346 0.04 GLY 22 -0.10 LYS 93

ASN 346 0.05 TYR 23 -0.09 GLY 104

ASN 346 0.05 ASP 24 -0.11 ALA 91

ASN 346 0.06 ILE 25 -0.09 GLY 104

ASN 346 0.06 ARG 26 -0.09 LYS 180

ASN 346 0.07 LEU 27 -0.09 LYS 180

ASN 346 0.08 ARG 28 -0.08 LYS 180

ASN 346 0.09 PRO 29 -0.08 LYS 180

ASN 346 0.09 ASP 30 -0.08 LYS 180

ASN 346 0.08 PHE 31 -0.08 LYS 180

ASN 346 0.08 GLY 32 -0.08 LYS 180

ASN 346 0.09 GLY 33 -0.08 LYS 180

ASN 346 0.10 PRO 34 -0.08 LEU 357

ASN 346 0.11 PRO 35 -0.08 LEU 357

ASN 346 0.11 VAL 36 -0.08 LEU 357

ASN 346 0.13 ALA 37 -0.09 LEU 357

ASN 346 0.13 VAL 38 -0.09 LEU 357

ASN 346 0.14 GLY 39 -0.10 LEU 357

ASN 346 0.15 MET 40 -0.11 LEU 357

ASN 346 0.16 ASN 41 -0.11 LEU 357

ASN 346 0.16 ILE 42 -0.12 LEU 357

LEU 345 0.16 ASP 43 -0.13 LEU 357

LEU 345 0.17 ILE 44 -0.14 LEU 357

LEU 345 0.16 ALA 45 -0.13 VAL 340

LEU 345 0.17 SER 46 -0.15 VAL 340

LEU 345 0.19 ILE 47 -0.15 VAL 340

LEU 345 0.18 ASP 48 -0.15 VAL 340

LEU 345 0.20 MET 49 -0.15 VAL 340

LEU 345 0.23 VAL 50 -0.13 LEU 357

LEU 345 0.24 SER 51 -0.11 LEU 357

LEU 345 0.28 GLU 52 -0.12 LEU 357

PRO 273 0.28 VAL 53 -0.09 LEU 357

LEU 345 0.22 ASN 54 -0.08 VAL 340

LEU 345 0.25 MET 55 -0.11 LEU 357

LEU 345 0.22 ASP 56 -0.11 LEU 357

LEU 345 0.21 TYR 57 -0.12 LEU 357

LEU 345 0.18 THR 58 -0.11 VAL 340

LEU 345 0.17 LEU 59 -0.12 LEU 357

LEU 345 0.15 THR 60 -0.12 VAL 340

LEU 345 0.16 MET 61 -0.11 LEU 357

LEU 345 0.14 TYR 62 -0.10 LEU 357

ASN 346 0.14 PHE 63 -0.09 LEU 357

ASN 346 0.13 GLN 64 -0.09 LEU 357

ASN 346 0.13 GLN 65 -0.08 LEU 357

ASN 346 0.13 ALA 66 -0.08 LEU 357

ASN 346 0.12 TRP 67 -0.07 LEU 357

ASN 346 0.11 ARG 68 -0.09 THR 123

ASN 346 0.09 ASP 69 -0.09 THR 123

ASN 346 0.09 LYS 70 -0.11 ASN 11

ASN 346 0.07 ARG 71 -0.13 ASN 11

ASN 346 0.08 LEU 72 -0.09 ASN 11

ASN 346 0.09 SER 73 -0.10 ASP 10

ASN 346 0.08 TYR 74 -0.10 ASP 10

ASN 346 0.09 ASN 75 -0.09 ASP 10

ASN 346 0.08 VAL 76 -0.09 ASP 10

LEU 345 0.09 ILE 77 -0.07 ASP 10

ASN 346 0.10 PRO 78 -0.07 ASP 10

LEU 345 0.10 LEU 79 -0.06 ASP 10

LEU 345 0.10 ASN 80 -0.07 ASN 11

LEU 345 0.09 LEU 81 -0.07 ASP 10

LEU 345 0.10 THR 82 -0.06 ASP 10

LEU 345 0.09 LEU 83 -0.07 ASP 10

LEU 345 0.08 ASP 84 -0.07 VAL 103

LEU 345 0.08 ASN 85 -0.09 ALA 88

LYS 21 0.07 ARG 86 -0.11 ALA 88

LEU 345 0.07 VAL 87 -0.09 GLY 104

LEU 345 0.08 ALA 88 -0.11 ARG 86

ASP 17 0.07 ASP 89 -0.11 GLY 104

GLU 14 0.06 GLN 90 -0.11 GLY 104

ASN 346 0.07 LEU 91 -0.09 GLY 104

ASN 346 0.08 TRP 92 -0.08 GLY 104

ASN 346 0.09 VAL 93 -0.07 LYS 180

ASN 346 0.11 PRO 94 -0.07 LEU 357

ASN 346 0.10 ASP 95 -0.08 LYS 180

ASN 346 0.13 THR 96 -0.09 LEU 357

ASN 346 0.14 TYR 97 -0.09 LEU 357

ASN 346 0.16 PHE 98 -0.10 LEU 357

ASN 346 0.17 LEU 99 -0.10 LEU 357

ASN 346 0.19 ASN 100 -0.11 LEU 357

ASN 346 0.17 ASP 101 -0.10 LEU 357

LEU 345 0.15 LYS 102 -0.10 THR 133

LEU 345 0.13 LYS 103 -0.10 LYS 118

LEU 345 0.13 SER 104 -0.12 LYS 118

LEU 345 0.11 PHE 105 -0.13 LYS 118

LEU 345 0.11 VAL 106 -0.13 MET 112

LEU 345 0.10 HIS 107 -0.10 PHE 105

LEU 345 0.09 GLY 108 -0.09 VAL 108

LEU 345 0.09 VAL 109 -0.10 VAL 340

LEU 345 0.08 THR 110 -0.10 VAL 340

LEU 345 0.08 VAL 111 -0.08 VAL 340

LEU 345 0.09 LYS 112 -0.09 ASN 111

LEU 345 0.10 ASN 113 -0.08 THR 113

LEU 345 0.10 ARG 114 -0.09 MET 114

LEU 345 0.11 MET 115 -0.08 GLY 173

LEU 345 0.10 ILE 116 -0.05 LYS 180

LEU 345 0.10 ARG 117 -0.06 ASN 11

ASN 346 0.10 LEU 118 -0.07 ASN 11

ASN 346 0.10 HIS 119 -0.07 ASN 11

ASN 346 0.10 PRO 120 -0.07 ASN 11

ASN 346 0.10 ASP 121 -0.08 ASN 11

ASN 346 0.10 GLY 122 -0.09 ASN 11

ASN 346 0.11 THR 123 -0.09 ARG 68

ASN 346 0.10 VAL 124 -0.06 LEU 357

ASN 346 0.11 LEU 125 -0.07 GLY 173

ASN 346 0.11 TYR 126 -0.06 GLY 173

LEU 345 0.12 GLY 127 -0.07 TYR 172

LEU 345 0.12 LEU 128 -0.08 THR 113

LEU 345 0.13 ARG 129 -0.08 VAL 340

LEU 345 0.13 ILE 130 -0.08 LEU 357

LEU 345 0.14 THR 131 -0.09 VAL 340

LEU 345 0.16 THR 132 -0.09 LEU 357

LEU 345 0.16 THR 133 -0.10 LYS 102

LEU 345 0.18 ALA 134 -0.11 LEU 357

ASN 346 0.21 ALA 135 -0.11 LEU 357

ASN 346 0.25 CYS 136 -0.13 LEU 357

ASN 346 0.30 MET 137 -0.13 LEU 357

LEU 345 0.33 MET 138 -0.15 LEU 357

LEU 345 0.39 ASP 139 -0.16 LEU 357

LEU 345 0.40 LEU 140 -0.16 LEU 357

LEU 345 0.46 ARG 141 -0.16 LEU 357

LEU 345 0.43 ARG 142 -0.21 LEU 357

LEU 345 0.38 TYR 143 -0.19 LEU 357

LEU 345 0.34 PRO 144 -0.22 LEU 357

LEU 345 0.35 LEU 145 -0.27 LEU 357

LEU 345 0.35 ASP 146 -0.24 LEU 357

LEU 345 0.32 GLU 147 -0.24 LEU 357

LEU 345 0.31 GLN 148 -0.20 LEU 357

ASN 346 0.29 ASN 149 -0.19 LEU 357

ASN 346 0.25 CYS 150 -0.15 LEU 357

ASN 346 0.24 THR 151 -0.15 LEU 357

ASN 346 0.21 LEU 152 -0.13 LEU 357

ASN 346 0.20 GLU 153 -0.12 LEU 357

ASN 346 0.17 ILE 154 -0.11 LEU 357

ASN 346 0.16 GLU 155 -0.10 LEU 357

ASN 346 0.13 SER 156 -0.09 LEU 357

ASN 346 0.12 TYR 157 -0.09 LEU 357

ASN 346 0.10 GLY 158 -0.09 LYS 180

ASN 346 0.11 TYR 159 -0.08 LEU 357

ASN 346 0.12 THR 160 -0.09 LEU 357

ASN 346 0.13 THR 161 -0.09 LEU 357

ASN 346 0.12 ASP 162 -0.09 LEU 357

ASN 346 0.11 ASP 163 -0.08 LEU 357

ASN 346 0.12 ILE 164 -0.09 LEU 357

ASN 346 0.14 GLU 165 -0.10 LEU 357

ASN 346 0.15 PHE 166 -0.11 LEU 357

ASN 346 0.16 TYR 167 -0.11 LEU 357

ASN 346 0.17 TRP 168 -0.12 LEU 357

ASN 346 0.16 ARG 169 -0.12 THR 216

ASN 346 0.17 GLY 170 -0.13 LEU 357

ASN 346 0.18 ASP 171 -0.14 LEU 357

ASN 346 0.19 ASP 172 -0.16 LEU 357

ASN 346 0.18 ASN 173 -0.16 LEU 357

ASN 346 0.17 ALA 174 -0.14 LEU 357

ASN 346 0.18 VAL 175 -0.15 LEU 357

ASN 346 0.18 THR 176 -0.16 LEU 357

LEU 345 0.18 GLY 177 -0.18 LEU 357

LEU 345 0.20 VAL 178 -0.21 LEU 357

LEU 345 0.20 THR 179 -0.25 LEU 357

LEU 345 0.19 LYS 180 -0.24 LEU 357

LEU 345 0.20 ILE 181 -0.22 LEU 357

LEU 345 0.20 GLU 182 -0.24 LEU 357

LEU 345 0.22 LEU 183 -0.22 LEU 357

LEU 345 0.22 PRO 184 -0.25 VAL 340

LEU 345 0.24 GLN 185 -0.26 VAL 340

LEU 345 0.25 PHE 186 -0.25 VAL 340

LEU 345 0.25 SER 187 -0.28 LEU 357

LEU 345 0.24 ILE 188 -0.26 LEU 357

ASN 346 0.25 VAL 189 -0.26 LEU 357

ASN 346 0.24 ASP 190 -0.23 LEU 357

ASN 346 0.23 TYR 191 -0.21 LEU 357

ASN 346 0.23 LYS 192 -0.19 LEU 357

ASN 346 0.21 LEU 193 -0.17 LEU 357

ASN 346 0.21 ILE 194 -0.15 LEU 357

ASN 346 0.20 THR 195 -0.14 LEU 357

ASN 346 0.19 LYS 196 -0.13 LEU 357

ASN 346 0.18 LYS 197 -0.12 LEU 357

ASN 346 0.18 VAL 198 -0.11 LEU 357

ASN 346 0.16 VAL 199 -0.10 LEU 357

ASN 346 0.15 PHE 200 -0.10 VAL 340

ASN 346 0.12 SER 201 -0.11 VAL 340

ASN 346 0.10 THR 202 -0.10 VAL 340

ASN 346 0.12 GLY 203 -0.09 LEU 357

ASN 346 0.14 SER 204 -0.10 LEU 357

ASN 346 0.15 TYR 205 -0.10 LEU 357

ASN 346 0.16 PRO 206 -0.11 LEU 357

ASN 346 0.18 ARG 207 -0.12 LEU 357

ASN 346 0.19 LEU 208 -0.13 LEU 357

ASN 346 0.21 SER 209 -0.14 LEU 357

ASN 346 0.21 LEU 210 -0.16 LEU 357

ASN 346 0.24 SER 211 -0.17 LEU 357

ASN 346 0.24 PHE 212 -0.19 LEU 357

ASN 346 0.27 LYS 213 -0.21 LEU 357

LEU 345 0.27 LEU 214 -0.23 LEU 357

LEU 345 0.29 LYS 215 -0.27 LEU 357

LEU 345 0.29 ARG 216 -0.27 VAL 340

LEU 345 0.27 ASN 217 -0.36 VAL 340

LEU 345 0.28 ILE 218 -0.39 VAL 340

LEU 345 0.25 GLY 219 -0.41 TYR 292

LEU 345 0.24 TYR 220 -0.25 VAL 340

LEU 345 0.27 PHE 221 -0.22 TRP 336

LEU 345 0.26 ILE 222 -0.30 TRP 336

LEU 338 0.24 LEU 223 -0.34 ASP 297

LEU 338 0.24 GLN 224 -0.17 THR 281

LEU 338 0.27 THR 225 -0.16 SER 353

LEU 338 0.29 TYR 226 -0.22 SER 353

GLY 334 0.27 MET 227 -0.31 SER 301

GLY 334 0.27 PRO 228 -0.26 THR 277

GLY 334 0.31 SER 229 -0.17 THR 277

GLY 334 0.31 ILE 230 -0.21 ASN 332

GLY 334 0.29 LEU 231 -0.27 VAL 273

GLY 334 0.30 ILE 232 -0.22 VAL 273

GLY 334 0.34 THR 233 -0.16 THR 256

GLY 334 0.30 ILE 234 -0.27 PRO 325

GLY 334 0.28 LEU 235 -0.26 ILE 270

GLY 334 0.32 SER 236 -0.17 THR 256

GLY 334 0.31 TRP 237 -0.21 PRO 325

GLY 334 0.27 VAL 238 -0.26 THR 266

GLY 334 0.27 SER 239 -0.19 THR 266

GLY 334 0.28 PHE 240 -0.19 ILE 322

GLY 334 0.24 TRP 241 -0.35 ILE 322

GLY 334 0.23 ILE 242 -0.23 ILE 322

GLY 334 0.20 ASN 243 -0.19 ILE 322

GLY 334 0.20 TYR 244 -0.12 ILE 322

SER 322 0.20 ASP 245 -0.12 ILE 322

HIS 318 0.20 ALA 246 -0.16 ALA 249

LEU 247 0.23 SER 247 -0.18 ALA 249

PRO 263 0.27 ALA 248 -0.29 ALA 249

GLY 334 0.21 ALA 249 -0.25 ALA 248

GLY 334 0.24 ARG 250 -0.20 ALA 249

GLY 334 0.25 VAL 251 -0.20 ALA 249

GLY 334 0.22 ALA 252 -0.27 ALA 252

GLY 334 0.25 LEU 253 -0.23 ALA 252

GLY 334 0.30 GLY 254 -0.17 ALA 252

LEU 240 0.29 ILE 255 -0.20 THR 256

GLY 334 0.26 THR 256 -0.26 THR 256

GLY 334 0.30 THR 257 -0.21 THR 256

GLY 334 0.34 VAL 258 -0.19 THR 256

MET 236 0.32 LEU 259 -0.24 THR 260

GLY 334 0.27 THR 260 -0.21 LEU 259

GLY 334 0.32 MET 261 -0.18 THR 260

PRO 233 0.37 THR 262 -0.22 THR 268

PRO 233 0.29 THR 263 -0.23 THR 263

GLY 334 0.26 ILE 264 -0.19 THR 263

ILE 228 0.29 ASN 265 -0.17 THR 268

PRO 233 0.31 THR 266 -0.19 THR 268

ILE 228 0.24 HIS 267 -0.19 HIS 267

LEU 345 0.25 LEU 268 -0.12 ASN 275

ILE 228 0.27 ARG 269 -0.14 SER 272

GLN 229 0.20 GLU 270 -0.19 ASN 275

LEU 345 0.20 THR 271 -0.16 ASN 275

LEU 345 0.24 LEU 272 -0.13 ASN 275

VAL 53 0.28 PRO 273 -0.13 SER 276

LEU 345 0.28 LYS 274 -0.13 VAL 340

LEU 345 0.37 ILE 275 -0.12 ILE 333

LEU 345 0.50 PRO 276 -0.13 ILE 333

LEU 345 0.59 TYR 277 -0.11 SER 353

LEU 345 0.56 VAL 278 -0.13 SER 353

LEU 345 0.47 LYS 279 -0.15 SER 353

LEU 345 0.44 ALA 280 -0.20 SER 353

LEU 345 0.38 ILE 281 -0.18 SER 353

LEU 345 0.43 ASP 282 -0.14 MET 286

TRP 341 0.48 MET 283 -0.17 SER 353

LEU 338 0.43 TYR 284 -0.20 SER 353

LEU 338 0.40 LEU 285 -0.15 SER 353

LEU 338 0.47 MET 286 -0.14 ASP 282

LEU 338 0.49 GLY 287 -0.17 SER 353

GLY 334 0.42 CYS 288 -0.16 SER 353

GLY 334 0.43 PHE 289 -0.13 THR 268

GLY 334 0.54 VAL 290 -0.12 SER 353

GLY 334 0.47 PHE 291 -0.14 SER 353

GLY 334 0.40 VAL 292 -0.14 PRO 325

GLY 334 0.46 PHE 293 -0.13 PRO 325

GLY 334 0.51 MET 294 -0.12 GLU 298

GLY 334 0.39 ALA 295 -0.13 PRO 325

GLY 334 0.37 LEU 296 -0.14 PRO 325

GLY 334 0.42 LEU 297 -0.13 PRO 325

GLY 334 0.37 GLU 298 -0.12 MET 294

GLY 334 0.30 TYR 299 -0.13 ILE 322

TRP 246 0.32 ALA 300 -0.13 PRO 325

ILE 327 0.32 LEU 301 -0.11 SER 329

GLY 334 0.25 VAL 302 -0.11 ILE 322

GLY 334 0.20 ASN 303 -0.12 ILE 322

ARG 323 0.24 TYR 304 -0.12 ILE 322

ARG 323 0.22 ILE 305 -0.10 SER 329

ARG 323 0.15 PHE 306 -0.10 ILE 322

SER 322 0.14 PHE 307 -0.09 ILE 322

LYS 320 0.17 SER 308 -0.08 PRO 233

ARG 323 0.15 GLN 309 -0.08 TYR 277

ILE 335 0.15 PRO 310 -0.12 ALA 314

ILE 335 0.17 ALA 311 -0.16 ALA 315

ILE 335 0.20 ARG 312 -0.12 MET 294

GLY 334 0.20 ALA 313 -0.10 MET 294

GLY 334 0.21 ALA 314 -0.12 PRO 310

GLY 334 0.26 ALA 315 -0.16 ALA 311

GLY 334 0.31 ILE 316 -0.12 SER 353

GLY 334 0.28 ASP 317 -0.12 SER 323

GLY 334 0.29 ARG 318 -0.29 SER 323

GLY 334 0.35 TRP 319 -0.25 SER 323

GLY 334 0.38 SER 320 -0.21 THR 316

GLY 334 0.34 ARG 321 -0.33 TYR 319

GLY 334 0.37 ILE 322 -0.47 THR 316

GLY 334 0.44 PHE 323 -0.34 THR 316

GLY 334 0.44 PHE 324 -0.27 THR 316

GLY 334 0.40 PRO 325 -0.38 VAL 312

GLY 334 0.45 VAL 326 -0.37 THR 316

GLY 334 0.53 VAL 327 -0.30 VAL 349

GLY 334 0.48 PHE 328 -0.30 VAL 349

LEU 338 0.46 SER 329 -0.40 VAL 349

LEU 338 0.55 PHE 330 -0.38 VAL 349

LEU 338 0.58 PHE 331 -0.34 SER 353

LEU 338 0.49 ASN 332 -0.39 SER 353

LEU 338 0.49 ILE 333 -0.46 SER 353

LEU 338 0.56 VAL 334 -0.39 SER 353

LEU 338 0.52 TYR 335 -0.35 SER 353

ALA 342 0.45 TRP 336 -0.43 SER 353

ALA 342 0.50 LEU 337 -0.45 SER 353

ALA 342 0.55 TYR 338 -0.38 SER 353

LEU 345 0.49 TYR 339 -0.36 SER 353

LEU 345 0.44 VAL 340 -0.45 LEU 357

ASN 346 0.06 ASP 10 -0.11 ARG 71

ASN 346 0.07 ASN 11 -0.13 ARG 71

GLY 32 0.06 THR 12 -0.11 ARG 71

ASN 346 0.05 THR 13 -0.09 LYS 180

ASN 346 0.05 VAL 14 -0.09 LYS 180

ASN 346 0.05 PHE 15 -0.09 LYS 180

THR 195 0.04 THR 16 -0.09 LYS 180

THR 195 0.04 ARG 17 -0.10 ASP 20

THR 195 0.04 ILE 18 -0.10 LYS 180

ASP 163 0.05 LEU 19 -0.10 LYS 180

SER 7 0.05 ASP 20 -0.10 ARG 17

SER 7 0.06 ARG 21 -0.09 LYS 180

SER 7 0.05 LEU 22 -0.10 LYS 180

MET 90 0.09 LEU 23 -0.10 LYS 180

SER 7 0.07 ASP 24 -0.09 LYS 180

SER 10 0.11 GLY 25 -0.08 LYS 180

MET 90 0.09 TYR 26 -0.09 LYS 180

LYS 93 0.10 ASP 27 -0.10 ALA 88

ILE 94 0.11 ASN 28 -0.09 TYR 26

PRO 115 0.08 ARG 29 -0.09 THR 176

TRP 95 0.07 LEU 30 -0.11 LYS 180

TRP 95 0.06 ARG 31 -0.12 LYS 180

TYR 338 0.05 PRO 32 -0.12 LYS 180

ASP 10 0.05 GLY 33 -0.13 LYS 180

ASP 10 0.06 LEU 34 -0.13 LYS 180

ASP 10 0.07 GLY 35 -0.12 LYS 180

ASP 10 0.06 GLU 36 -0.13 LYS 180

TYR 338 0.06 ARG 37 -0.13 LYS 180

TYR 338 0.06 VAL 38 -0.15 LYS 180

TYR 338 0.06 THR 39 -0.15 LYS 180

TYR 338 0.06 GLU 40 -0.15 LYS 180

TYR 338 0.07 VAL 41 -0.15 LYS 180

TYR 338 0.07 LYS 42 -0.14 LYS 180

TYR 338 0.08 THR 43 -0.14 LYS 180

TYR 338 0.08 ASP 44 -0.13 LYS 180

ASN 346 0.09 ILE 45 -0.13 VAL 340

ASN 346 0.14 PHE 46 -0.11 VAL 340

ASN 346 0.17 VAL 47 -0.12 VAL 340

ASN 346 0.19 THR 48 -0.11 VAL 340

ASN 346 0.21 SER 49 -0.11 VAL 340

ASN 346 0.21 PHE 50 -0.13 VAL 340

ASN 346 0.20 GLY 51 -0.12 VAL 340

ASN 346 0.20 PRO 52 -0.13 VAL 340

ASN 346 0.16 VAL 53 -0.15 VAL 340

LEU 345 0.13 SER 54 -0.15 VAL 340

PRO 147 0.12 ASP 55 -0.17 PRO 278

ASP 48 0.11 HIS 56 -0.16 PRO 278

ASP 48 0.12 ASP 57 -0.15 PRO 184

THR 60 0.08 MET 58 -0.22 PRO 184

THR 131 0.07 GLU 59 -0.17 PRO 184

ASN 346 0.12 TYR 60 -0.14 VAL 340

ASN 346 0.14 THR 61 -0.12 VAL 340

ASN 346 0.15 ILE 62 -0.11 VAL 340

ASN 346 0.16 ASP 63 -0.10 VAL 340

ASN 346 0.13 VAL 64 -0.11 VAL 340

ASN 346 0.12 PHE 65 -0.11 VAL 340

ASN 346 0.08 PHE 66 -0.12 LYS 180

TYR 338 0.07 ARG 67 -0.12 LYS 180

TYR 338 0.06 GLN 68 -0.14 LYS 180

TYR 338 0.07 SER 69 -0.13 LYS 180

TYR 338 0.06 TRP 70 -0.14 LYS 180

TYR 338 0.06 LYS 71 -0.13 LYS 180

TYR 338 0.05 ASP 72 -0.12 LYS 180

TYR 338 0.05 GLU 73 -0.12 LYS 180

TYR 338 0.05 ARG 74 -0.11 LYS 180

TYR 338 0.05 LEU 75 -0.11 LYS 180

TYR 338 0.05 LYS 76 -0.10 LYS 180

TYR 338 0.04 PHE 77 -0.10 LYS 180

TYR 338 0.04 LYS 78 -0.09 LYS 180

ASN 346 0.04 GLY 79 -0.09 LYS 180

ASN 346 0.05 PRO 80 -0.09 LYS 180

ASN 346 0.05 MET 81 -0.09 LYS 180

TYR 338 0.05 THR 82 -0.10 LYS 180

ASN 346 0.05 VAL 83 -0.10 LYS 180

ASN 346 0.05 LEU 84 -0.10 LYS 180

ASN 346 0.07 ARG 85 -0.10 LYS 180

ASN 346 0.06 LEU 86 -0.10 LYS 180

GLY 158 0.07 ASN 87 -0.09 LYS 180

ASP 27 0.08 ASN 88 -0.10 THR 110

ASP 27 0.09 LEU 89 -0.10 VAL 111

ASP 27 0.10 MET 90 -0.20 ALA 91

LYS 117 0.10 ALA 91 -0.20 MET 90

PRO 115 0.10 SER 92 -0.10 ASP 24

ASP 27 0.10 LYS 93 -0.10 GLY 22

ASN 28 0.11 ILE 94 -0.10 LYS 180

ASN 28 0.08 TRP 95 -0.11 LYS 180

ASN 28 0.06 THR 96 -0.12 LYS 180

TYR 338 0.06 PRO 97 -0.14 LYS 180

ASP 84 0.06 ASP 98 -0.14 LYS 180

TYR 338 0.06 THR 99 -0.16 LYS 180

SER 159 0.06 PHE 100 -0.14 LYS 180

ARG 136 0.07 PHE 101 -0.15 ILE 181

TYR 338 0.06 HIS 102 -0.20 ILE 181

ARG 136 0.07 ASN 103 -0.21 GLU 182

ARG 136 0.12 GLY 104 -0.15 GLU 182

ARG 136 0.10 LYS 105 -0.15 LYS 106

HIS 107 0.10 LYS 106 -0.16 LYS 106

LEU 345 0.09 SER 107 -0.15 LYS 106

LEU 345 0.10 VAL 108 -0.17 ALA 109

ARG 86 0.11 ALA 109 -0.17 VAL 108

ASN 346 0.10 HIS 110 -0.11 ASP 120

ARG 86 0.10 ASN 111 -0.11 VAL 106

ASN 346 0.12 MET 112 -0.13 VAL 106

ASN 346 0.12 THR 113 -0.11 VAL 106

ASN 346 0.10 MET 114 -0.10 VAL 106

SER 92 0.10 PRO 115 -0.10 TRP 123

ASN 346 0.10 ASN 116 -0.09 TRP 123

ALA 91 0.10 LYS 117 -0.10 LYS 180

ALA 91 0.09 LEU 118 -0.10 LYS 180

ASP 27 0.07 LEU 119 -0.11 LYS 180

ASN 346 0.05 ARG 120 -0.11 LYS 180

TYR 338 0.05 ILE 121 -0.11 LYS 180

TYR 338 0.05 THR 122 -0.11 LYS 180

TYR 338 0.05 GLU 123 -0.10 LYS 180

TYR 338 0.05 ASP 124 -0.11 LYS 180

TYR 338 0.05 GLY 125 -0.12 LYS 180

TYR 338 0.05 THR 126 -0.12 LYS 180

THR 202 0.06 LEU 127 -0.12 LYS 180

THR 202 0.08 LEU 128 -0.12 LYS 180

ASN 28 0.06 TYR 129 -0.12 LYS 180

ASN 346 0.07 THR 130 -0.11 LYS 180

ASN 346 0.08 MET 131 -0.11 LYS 180

ASN 346 0.11 ARG 132 -0.10 GLU 182

ASN 346 0.10 LEU 133 -0.11 LYS 106

ASN 346 0.12 THR 134 -0.12 LYS 106

VAL 109 0.13 VAL 135 -0.13 LYS 106

GLY 104 0.12 ARG 136 -0.13 LYS 106

TYR 277 0.07 ALA 137 -0.14 PRO 184

TYR 277 0.07 GLU 138 -0.18 PRO 184

TYR 338 0.10 CYS 139 -0.20 PRO 184

TYR 338 0.10 PRO 140 -0.27 GLU 182

TYR 338 0.12 MET 141 -0.24 PRO 184

TYR 338 0.13 HIS 142 -0.27 VAL 340

TYR 338 0.14 LEU 143 -0.28 VAL 340

TYR 338 0.15 GLU 144 -0.31 ARG 347

TYR 338 0.21 ASP 145 -0.30 VAL 340

TYR 338 0.18 PHE 146 -0.25 VAL 340

TYR 277 0.20 PRO 147 -0.22 VAL 340

ARG 347 0.30 MET 148 -0.23 VAL 340

TYR 338 0.22 ASP 149 -0.24 VAL 340

ARG 347 0.25 ALA 150 -0.23 VAL 340

TYR 338 0.16 HIS 151 -0.22 VAL 340

TYR 338 0.15 ALA 152 -0.20 VAL 340

TYR 338 0.10 CYS 153 -0.17 VAL 340

TYR 338 0.09 PRO 154 -0.20 GLU 182

TYR 338 0.09 LEU 155 -0.18 GLU 182

TYR 338 0.08 LYS 156 -0.21 LYS 180

TYR 338 0.08 PHE 157 -0.19 LYS 180

TYR 338 0.07 GLY 158 -0.19 LYS 180

TYR 338 0.07 SER 159 -0.17 LYS 180

ASP 10 0.07 TYR 160 -0.16 LYS 180

ASP 10 0.07 ALA 161 -0.16 GLY 177

ASP 10 0.07 TYR 162 -0.16 GLY 177

ASP 10 0.07 THR 163 -0.19 GLY 177

ASP 10 0.06 ARG 164 -0.19 LYS 180

ASP 10 0.06 ALA 165 -0.16 LYS 180

ASP 10 0.06 GLU 166 -0.15 LYS 180

TYR 338 0.06 VAL 167 -0.16 LYS 180

TYR 338 0.07 VAL 168 -0.17 LYS 180

TYR 338 0.08 TYR 169 -0.17 LYS 180

TYR 338 0.08 GLU 170 -0.16 LYS 180

TYR 338 0.09 TRP 171 -0.15 LYS 180

TYR 338 0.09 THR 172 -0.12 LYS 180

TYR 338 0.10 ARG 173 -0.13 VAL 340

TYR 338 0.11 GLU 174 -0.14 VAL 340

TYR 338 0.11 PRO 175 -0.15 VAL 340

TYR 338 0.12 ALA 176 -0.15 VAL 340

TYR 338 0.12 ARG 177 -0.14 VAL 340

TYR 338 0.10 SER 178 -0.14 VAL 340

ARG 347 0.11 VAL 179 -0.14 VAL 340

ARG 347 0.16 VAL 180 -0.13 VAL 340

ASN 346 0.20 VAL 181 -0.12 VAL 340

ASN 346 0.23 ALA 182 -0.11 VAL 340

ASN 346 0.29 GLU 183 -0.11 VAL 340

ASN 346 0.29 ASP 184 -0.11 LEU 357

ASN 346 0.25 GLY 185 -0.11 VAL 340

ASN 346 0.28 SER 186 -0.12 VAL 340

ASN 346 0.26 ARG 187 -0.12 VAL 340

ASN 346 0.29 LEU 188 -0.13 VAL 340

LEU 345 0.33 ASN 189 -0.12 VAL 340

LEU 345 0.33 GLN 190 -0.15 VAL 340

ARG 347 0.33 TYR 191 -0.16 VAL 340

ARG 347 0.39 ASP 192 -0.16 VAL 340

ARG 347 0.32 LEU 193 -0.16 VAL 340

ARG 347 0.36 LEU 194 -0.16 VAL 340

ARG 347 0.26 GLY 195 -0.16 VAL 340

ARG 347 0.16 GLN 196 -0.16 VAL 340

TYR 338 0.14 THR 197 -0.17 VAL 340

TYR 338 0.12 VAL 198 -0.16 VAL 340

TYR 338 0.10 ASP 199 -0.20 LYS 180

TYR 338 0.09 SER 200 -0.21 LYS 180

TYR 338 0.08 GLY 201 -0.24 LYS 180

TYR 338 0.08 ILE 202 -0.24 LYS 180

TYR 338 0.08 VAL 203 -0.28 LYS 180

TYR 338 0.07 GLN 204 -0.27 GLY 177

TYR 338 0.07 SER 205 -0.31 THR 176

ASN 346 0.07 SER 206 -0.30 THR 176

ASP 10 0.07 THR 207 -0.20 THR 176

ASP 10 0.07 GLY 208 -0.24 THR 176

TYR 338 0.07 GLU 209 -0.22 GLY 177

TYR 338 0.07 TYR 210 -0.22 LYS 180

TYR 338 0.08 VAL 211 -0.21 LYS 180

TYR 338 0.08 VAL 212 -0.23 LYS 180

TYR 338 0.09 MET 213 -0.20 LYS 180

TYR 338 0.10 THR 214 -0.20 LYS 180

TYR 338 0.11 THR 215 -0.17 GLU 182

TYR 338 0.11 HIS 216 -0.18 VAL 340

ARG 347 0.15 PHE 217 -0.17 VAL 340

ARG 347 0.22 HIS 218 -0.18 VAL 340

ARG 347 0.28 LEU 219 -0.18 VAL 340

ARG 347 0.42 LYS 220 -0.19 VAL 340

ARG 347 0.37 ARG 221 -0.18 VAL 340

LEU 345 0.48 LYS 222 -0.17 VAL 340

LEU 345 0.56 ILE 223 -0.17 ILE 333

LEU 345 0.54 GLY 224 -0.16 ILE 333

LEU 345 0.39 TYR 225 -0.15 ILE 333

LEU 345 0.30 PHE 226 -0.17 ILE 333

LEU 345 0.38 VAL 227 -0.17 ILE 333

ASP 282 0.33 ILE 228 -0.15 ILE 333

THR 266 0.26 GLN 229 -0.15 ILE 333

THR 266 0.20 THR 230 -0.18 ILE 333

TRP 341 0.25 TYR 231 -0.19 ILE 333

MET 286 0.32 LEU 232 -0.17 ILE 333

THR 262 0.37 PRO 233 -0.18 MET 236

THR 262 0.25 CYS 234 -0.20 SER 329

ASN 337 0.29 ILE 235 -0.19 SER 329

LEU 259 0.32 MET 236 -0.18 PRO 233

LEU 259 0.27 THR 237 -0.18 SER 329

PHE 331 0.20 VAL 238 -0.21 SER 329

GLY 334 0.37 ILE 239 -0.18 SER 329

ILE 255 0.29 LEU 240 -0.17 SER 329

THR 271 0.18 SER 241 -0.19 PRO 325

GLY 334 0.22 GLN 242 -0.19 SER 329

GLY 334 0.26 VAL 243 -0.16 SER 329

PRO 263 0.21 SER 244 -0.18 ILE 322

ALA 300 0.18 PHE 245 -0.19 ILE 322

ALA 300 0.32 TRP 246 -0.16 ILE 322

SER 247 0.23 LEU 247 -0.15 ILE 322

PRO 263 0.19 ASN 248 -0.14 ILE 322

ALA 261 0.17 ARG 249 -0.15 ILE 322

ALA 261 0.19 GLU 250 -0.11 ILE 322

ALA 261 0.23 SER 251 -0.12 ILE 322

ALA 248 0.25 VAL 252 -0.14 ILE 322

PRO 253 0.26 PRO 253 -0.18 ILE 242

PRO 263 0.28 ALA 254 -0.15 ILE 322

PRO 263 0.20 ARG 255 -0.18 ILE 322

ALA 252 0.21 THR 256 -0.22 VAL 238

VAL 257 0.24 VAL 257 -0.19 VAL 238

PRO 263 0.19 PHE 258 -0.17 PRO 325

VAL 257 0.16 GLY 259 -0.21 LEU 235

VAL 257 0.18 VAL 260 -0.28 LEU 235

THR 261 0.21 THR 261 -0.20 LEU 235

THR 261 0.18 THR 262 -0.17 PRO 325

GLY 334 0.15 VAL 263 -0.20 LEU 235

THR 261 0.18 LEU 264 -0.19 LEU 259

THR 265 0.19 THR 265 -0.15 VAL 258

GLY 334 0.15 MET 266 -0.18 SER 329

GLY 334 0.16 THR 267 -0.16 LEU 231

THR 265 0.18 THR 268 -0.22 THR 262

THR 265 0.16 LEU 269 -0.14 ILE 333

GLY 334 0.14 SER 270 -0.17 ILE 333

PRO 233 0.15 ILE 271 -0.16 PRO 228

GLU 270 0.15 SER 272 -0.19 THR 266

PRO 233 0.12 ALA 273 -0.16 TRP 336

GLY 334 0.13 ARG 274 -0.17 TRP 336

THR 271 0.15 ASN 275 -0.19 GLU 270

THR 271 0.12 SER 276 -0.15 GLU 270

LEU 345 0.11 LEU 277 -0.16 VAL 340

LEU 345 0.12 PRO 278 -0.17 ASP 55

LEU 345 0.12 LYS 279 -0.19 VAL 340

GLY 334 0.13 VAL 280 -0.24 VAL 340

GLY 334 0.12 ALA 281 -0.38 ASN 217

GLY 334 0.11 TYR 282 -0.42 GLY 219

VAL 334 0.13 ALA 283 -0.41 GLY 219

TYR 338 0.15 THR 284 -0.31 VAL 340

TYR 338 0.19 ALA 285 -0.30 TRP 336

VAL 334 0.18 MET 286 -0.27 TRP 336

PHE 331 0.15 ASP 287 -0.33 LEU 223

PHE 331 0.19 TRP 288 -0.37 ILE 333

PHE 331 0.22 PHE 289 -0.31 ILE 333

PHE 331 0.15 ILE 290 -0.28 ILE 333

PHE 331 0.14 ALA 291 -0.36 ILE 333

PHE 331 0.19 VAL 292 -0.36 ILE 333

PHE 331 0.19 CYS 293 -0.29 SER 329

GLY 334 0.13 TYR 294 -0.29 SER 329

PHE 331 0.14 ALA 295 -0.38 SER 329

PHE 331 0.18 PHE 296 -0.33 SER 329

GLY 334 0.14 VAL 297 -0.26 SER 329

GLY 334 0.15 PHE 298 -0.30 PRO 325

GLY 334 0.13 SER 299 -0.31 PRO 325

GLY 334 0.13 ALA 300 -0.25 PRO 325

GLY 334 0.14 LEU 301 -0.25 PRO 325

GLY 334 0.14 ILE 302 -0.32 ILE 322

GLY 334 0.13 GLU 303 -0.29 ILE 322

ALA 249 0.13 PHE 304 -0.25 ILE 322

GLY 334 0.13 ALA 305 -0.29 ILE 322

GLY 334 0.12 THR 306 -0.33 ILE 322

GLY 334 0.12 VAL 307 -0.25 ILE 322

ALA 246 0.13 ASN 308 -0.21 ILE 322

GLY 334 0.12 TYR 309 -0.24 ILE 322

GLY 334 0.11 PHE 310 -0.22 ILE 322

ALA 246 0.11 THR 311 -0.17 ILE 322

ASP 245 0.10 LYS 312 -0.11 ILE 322

GLY 334 0.09 SER 313 -0.13 ILE 322

SER 308 0.11 GLN 314 -0.16 ILE 322

SER 308 0.13 PRO 315 -0.15 ILE 322

SER 308 0.17 ALA 316 -0.17 ILE 322

SER 308 0.14 ARG 317 -0.22 ILE 322

VAL 327 0.12 ALA 318 -0.21 ILE 322

TYR 304 0.18 ALA 319 -0.19 ILE 322

LEU 301 0.19 LYS 320 -0.22 ILE 322

VAL 327 0.18 ILE 321 -0.26 ILE 322

LEU 301 0.19 ASP 322 -0.23 ILE 322

LEU 301 0.27 ARG 323 -0.21 ILE 322

VAL 327 0.24 LEU 324 -0.25 VAL 326

VAL 327 0.22 SER 325 -0.27 VAL 326

LEU 297 0.28 ARG 326 -0.21 SER 329

VAL 327 0.34 ILE 327 -0.25 SER 329

VAL 327 0.31 ALA 328 -0.30 SER 329

VAL 327 0.29 PHE 329 -0.29 SER 329

VAL 327 0.38 PRO 330 -0.26 SER 329

VAL 327 0.41 LEU 331 -0.29 SER 329

PHE 331 0.34 LEU 332 -0.34 SER 329

PHE 331 0.36 PHE 333 -0.31 SER 329

PHE 331 0.55 GLY 334 -0.32 ILE 333

PHE 331 0.51 ILE 335 -0.41 ILE 333

PHE 331 0.42 PHE 336 -0.43 ILE 333

PHE 331 0.49 ASN 337 -0.34 ILE 333

PHE 331 0.58 LEU 338 -0.37 ILE 333

PHE 331 0.48 VAL 339 -0.45 ILE 333

PHE 331 0.42 TYR 340 -0.42 ILE 333

VAL 334 0.52 TRP 341 -0.34 ILE 333

VAL 334 0.56 ALA 342 -0.39 ILE 333

VAL 334 0.46 THR 343 -0.43 LEU 337

TYR 277 0.44 TYR 344 -0.38 VAL 340

TYR 277 0.59 LEU 345 -0.33 VAL 340

TYR 338 0.53 ASN 346 -0.38 VAL 340

TYR 277 0.44 ARG 347 -0.42 VAL 340

GLY 25 0.09 SER 7 -0.10 LYS 180

ASP 10 0.07 ASN 8 -0.11 ASN 173

GLY 25 0.07 MET 9 -0.11 LYS 180

GLY 25 0.11 SER 10 -0.09 LYS 180

ASN 33 0.07 LEU 11 -0.10 ASN 173

ASP 10 0.07 VAL 12 -0.10 ASN 173

LYS 93 0.08 LYS 13 -0.09 THR 176

LEU 89 0.08 GLU 14 -0.08 GLY 170

THR 13 0.08 THR 15 -0.09 GLY 170

PRO 115 0.08 VAL 16 -0.08 GLY 170

PRO 115 0.09 ASP 17 -0.06 GLY 170

ASP 20 0.09 ARG 18 -0.06 GLY 170

THR 13 0.10 LEU 19 -0.07 ARG 169

ASN 111 0.08 LEU 20 -0.05 GLY 25

ASP 20 0.10 LYS 21 -0.05 GLY 25

ASP 20 0.15 GLY 22 -0.04 ASP 10

ASP 20 0.10 TYR 23 -0.05 ARG 17

ILE 25 0.10 ASP 24 -0.06 GLY 22

ASP 24 0.10 ILE 25 -0.07 GLY 22

ASP 24 0.09 ARG 26 -0.07 GLY 22

ASN 346 0.08 LEU 27 -0.06 GLY 22

ASN 346 0.09 ARG 28 -0.06 GLY 22

THR 12 0.09 PRO 29 -0.05 GLY 22

ASN 11 0.10 ASP 30 -0.05 GLY 22

ASN 346 0.09 PHE 31 -0.05 GLY 22

PRO 80 0.08 GLY 32 -0.05 GLY 22

PRO 34 0.15 GLY 33 -0.04 ARG 347

GLY 33 0.15 PRO 34 -0.06 ARG 347

ASN 346 0.10 PRO 35 -0.06 ARG 347

ASN 346 0.10 VAL 36 -0.06 LYS 70

ASN 346 0.11 ALA 37 -0.10 THR 123

ASN 346 0.10 VAL 38 -0.12 THR 123

ASN 346 0.11 GLY 39 -0.14 THR 123

ASN 346 0.11 MET 40 -0.11 THR 123

ASN 346 0.11 ASN 41 -0.15 SER 206

ASN 346 0.11 ILE 42 -0.16 SER 206

LEU 345 0.09 ASP 43 -0.16 SER 205

LEU 345 0.10 ILE 44 -0.12 SER 205

LEU 345 0.09 ALA 45 -0.18 HIS 102

LEU 345 0.10 SER 46 -0.17 HIS 102

LEU 345 0.11 ILE 47 -0.12 ASN 103

ASP 57 0.12 ASP 48 -0.13 LYS 105

LEU 345 0.11 MET 49 -0.12 ARG 136

LEU 345 0.13 VAL 50 -0.10 ARG 136

LEU 345 0.13 SER 51 -0.10 ARG 136

LEU 345 0.17 GLU 52 -0.10 ALA 281

PRO 273 0.15 VAL 53 -0.10 PRO 52

LEU 345 0.12 ASN 54 -0.16 PRO 52

LEU 345 0.15 MET 55 -0.10 PRO 52

LEU 345 0.13 ASP 56 -0.12 GLY 51

LEU 345 0.12 TYR 57 -0.10 ARG 136

LEU 345 0.10 THR 58 -0.13 VAL 108

LEU 345 0.10 LEU 59 -0.13 VAL 108

ASP 57 0.11 THR 60 -0.15 VAL 108

ASP 57 0.09 MET 61 -0.12 VAL 108

LEU 345 0.09 TYR 62 -0.13 ALA 161

LEU 345 0.09 PHE 63 -0.12 THR 113

ASN 346 0.09 GLN 64 -0.10 THR 113

ASN 346 0.09 GLN 65 -0.09 MET 40

ASP 10 0.09 ALA 66 -0.12 THR 123

ASP 10 0.11 TRP 67 -0.12 THR 123

ASP 10 0.14 ARG 68 -0.11 GLY 122

ASP 10 0.16 ASP 69 -0.06 LEU 19

ASP 10 0.25 LYS 70 -0.07 ALA 37

ASP 10 0.21 ARG 71 -0.05 ALA 37

ASP 10 0.16 LEU 72 -0.07 ARG 169

ASP 10 0.20 SER 73 -0.09 ARG 169

ASP 10 0.17 TYR 74 -0.10 GLY 170

ASP 10 0.15 ASN 75 -0.11 GLY 170

ASP 10 0.12 VAL 76 -0.10 GLY 170

ASP 10 0.11 ILE 77 -0.12 GLY 170

ASP 10 0.12 PRO 78 -0.14 GLY 170

ASP 10 0.11 LEU 79 -0.14 GLY 170

ASP 10 0.11 ASN 80 -0.14 GLY 170

ASP 10 0.10 LEU 81 -0.12 THR 176

ASP 10 0.08 THR 82 -0.13 THR 176

ASP 10 0.07 LEU 83 -0.11 THR 176

ALA 109 0.08 ASP 84 -0.10 GLY 177

ALA 109 0.09 ASN 85 -0.09 GLY 177

ALA 109 0.11 ARG 86 -0.08 GLY 22

ALA 109 0.09 VAL 87 -0.16 ALA 88

ALA 109 0.09 ALA 88 -0.16 VAL 87

LYS 103 0.09 ASP 89 -0.09 GLY 22

LYS 103 0.08 GLN 90 -0.08 GLY 22

LYS 103 0.07 LEU 91 -0.07 GLY 22

ASN 346 0.08 TRP 92 -0.06 GLY 22

ASN 346 0.08 VAL 93 -0.06 GLY 22

ASN 346 0.09 PRO 94 -0.06 GLY 22

ASN 346 0.09 ASP 95 -0.08 LEU 118

TYR 97 0.11 THR 96 -0.07 LEU 118

THR 96 0.11 TYR 97 -0.09 ARG 132

ASN 346 0.12 PHE 98 -0.08 VAL 64

ASN 346 0.13 LEU 99 -0.08 PHE 46

ASN 346 0.14 ASN 100 -0.10 THR 48

ALA 135 0.12 ASP 101 -0.14 ASP 63

LEU 345 0.10 LYS 102 -0.21 ASP 63

GLN 229 0.09 LYS 103 -0.22 VAL 108

LEU 345 0.08 SER 104 -0.21 VAL 108

SER 54 0.08 PHE 105 -0.21 VAL 108

SER 54 0.09 VAL 106 -0.18 VAL 108

ARG 136 0.11 HIS 107 -0.17 VAL 108

ARG 136 0.10 GLY 108 -0.15 VAL 108

VAL 135 0.13 VAL 109 -0.13 VAL 108

VAL 135 0.11 THR 110 -0.12 TRP 123

ALA 109 0.09 VAL 111 -0.11 TRP 123

ALA 88 0.08 LYS 112 -0.12 VAL 108

ARG 136 0.08 ASN 113 -0.12 VAL 108

MET 115 0.09 ARG 114 -0.11 MET 112

ARG 114 0.09 MET 115 -0.10 THR 113

ASP 10 0.08 ILE 116 -0.09 THR 176

ASP 10 0.09 ARG 117 -0.12 LEU 125

ASP 10 0.12 LEU 118 -0.12 ARG 169

ASP 10 0.14 HIS 119 -0.14 ARG 169

ASP 10 0.15 PRO 120 -0.12 GLY 170

ASP 10 0.18 ASP 121 -0.12 ARG 169

ASP 10 0.19 GLY 122 -0.11 ARG 68

ASP 10 0.15 THR 123 -0.14 GLY 39

ASP 10 0.11 VAL 124 -0.08 ASP 27

ASP 10 0.10 LEU 125 -0.12 ARG 117

ASP 10 0.08 TYR 126 -0.10 THR 113

LEU 345 0.07 GLY 127 -0.11 THR 113

ARG 136 0.08 LEU 128 -0.13 THR 113

ARG 136 0.09 ARG 129 -0.13 VAL 108

SER 54 0.09 ILE 130 -0.15 VAL 108

ASP 57 0.11 THR 131 -0.17 VAL 108

ASP 57 0.09 THR 132 -0.18 VAL 108

LEU 345 0.09 THR 133 -0.16 ASP 63

LEU 345 0.11 ALA 134 -0.13 ASP 63

LEU 345 0.13 ALA 135 -0.11 SER 49

LEU 345 0.17 CYS 136 -0.10 ARG 347

LEU 345 0.20 MET 137 -0.10 ARG 347

LEU 345 0.23 MET 138 -0.13 ARG 347

LEU 345 0.28 ASP 139 -0.14 ARG 347

LEU 345 0.29 LEU 140 -0.15 ARG 347

LEU 345 0.34 ARG 141 -0.16 THR 343

LEU 345 0.32 ARG 142 -0.20 THR 343

LEU 345 0.27 TYR 143 -0.18 ARG 347

LEU 345 0.24 PRO 144 -0.21 ARG 347

LEU 345 0.26 LEU 145 -0.26 ARG 347

LEU 345 0.26 ASP 146 -0.23 ARG 347

LEU 345 0.24 GLU 147 -0.24 ARG 347

LEU 345 0.22 GLN 148 -0.19 ARG 347

ASN 346 0.21 ASN 149 -0.18 ARG 347

ASN 346 0.17 CYS 150 -0.13 ARG 347

ASN 346 0.17 THR 151 -0.12 ARG 347

ASN 346 0.15 LEU 152 -0.11 SER 205

ASN 346 0.15 GLU 153 -0.10 SER 206

ASN 346 0.13 ILE 154 -0.10 SER 206

ASN 346 0.13 GLU 155 -0.08 GLY 208

ASN 346 0.11 SER 156 -0.07 THR 96

ASN 346 0.10 TYR 157 -0.06 THR 96

ASN 346 0.09 GLY 158 -0.05 GLY 22

ASN 346 0.10 TYR 159 -0.05 ARG 347

ASN 346 0.11 THR 160 -0.06 ARG 347

ASN 346 0.12 THR 161 -0.07 ARG 347

ASN 346 0.11 ASP 162 -0.06 ARG 347

ASN 346 0.10 ASP 163 -0.06 ARG 347

ASN 346 0.11 ILE 164 -0.06 ARG 347

ASN 346 0.12 GLU 165 -0.08 THR 123

ASN 346 0.12 PHE 166 -0.10 THR 123

ASN 346 0.13 TYR 167 -0.12 THR 123

ASN 346 0.13 TRP 168 -0.12 THR 123

ASN 346 0.12 ARG 169 -0.14 ASN 80

ASN 346 0.13 GLY 170 -0.17 SER 206

ASN 346 0.14 ASP 171 -0.15 SER 206

ASN 346 0.14 ASP 172 -0.18 SER 206

ASN 346 0.13 ASN 173 -0.25 SER 206

ASN 346 0.12 ALA 174 -0.25 SER 206

ASN 346 0.13 VAL 175 -0.25 SER 206

ASN 346 0.12 THR 176 -0.31 SER 205

LEU 345 0.12 GLY 177 -0.29 SER 205

ASN 346 0.13 VAL 178 -0.23 SER 205

ASN 346 0.14 THR 179 -0.27 ARG 347

LEU 345 0.12 LYS 180 -0.28 VAL 203

LEU 345 0.13 ILE 181 -0.21 VAL 203

LEU 345 0.13 GLU 182 -0.27 PRO 140

LEU 345 0.14 LEU 183 -0.24 PRO 140

LEU 345 0.14 PRO 184 -0.26 PRO 140

LEU 345 0.16 GLN 185 -0.21 ARG 347

LEU 345 0.17 PHE 186 -0.24 ARG 347

LEU 345 0.17 SER 187 -0.28 ARG 347

LEU 345 0.17 ILE 188 -0.25 ARG 347

ASN 346 0.18 VAL 189 -0.28 ARG 347

ASN 346 0.18 ASP 190 -0.24 ARG 347

ASN 346 0.17 TYR 191 -0.20 ARG 347

ASN 346 0.17 LYS 192 -0.18 ARG 347

ASN 346 0.16 LEU 193 -0.16 SER 206

ASN 346 0.16 ILE 194 -0.14 ARG 347

ASN 346 0.15 THR 195 -0.12 ARG 347

ASN 346 0.16 LYS 196 -0.11 ARG 347

ASN 346 0.15 LYS 197 -0.09 ARG 347

ASN 346 0.16 VAL 198 -0.09 ARG 347

ASN 346 0.15 VAL 199 -0.08 ARG 347

ASN 346 0.13 PHE 200 -0.07 ARG 347

ASN 346 0.12 SER 201 -0.06 ARG 347

ASN 346 0.10 THR 202 -0.06 ARG 347

ASN 346 0.11 GLY 203 -0.07 ARG 347

ASN 346 0.13 SER 204 -0.08 ARG 347

ASN 346 0.13 TYR 205 -0.07 ARG 347

ASN 346 0.13 PRO 206 -0.09 ARG 347

ASN 346 0.14 ARG 207 -0.09 ARG 347

ASN 346 0.15 LEU 208 -0.11 SER 206

ASN 346 0.16 SER 209 -0.12 SER 206

ASN 346 0.16 LEU 210 -0.14 SER 206

ASN 346 0.17 SER 211 -0.15 ARG 347

ASN 346 0.17 PHE 212 -0.17 ARG 347

ASN 346 0.19 LYS 213 -0.20 ARG 347

LEU 345 0.19 LEU 214 -0.23 ARG 347

LEU 345 0.20 LYS 215 -0.26 ARG 347

LEU 345 0.20 ARG 216 -0.25 ARG 347

LEU 345 0.18 ASN 217 -0.38 ALA 281

LEU 338 0.19 ILE 218 -0.33 VAL 340

LEU 338 0.17 GLY 219 -0.42 TYR 282

GLY 334 0.16 TYR 220 -0.23 ARG 347

LEU 338 0.18 PHE 221 -0.21 VAL 340

GLY 334 0.19 ILE 222 -0.28 TRP 336

GLY 334 0.17 LEU 223 -0.33 ASP 287

GLY 334 0.17 GLN 224 -0.18 ASP 287

GLY 334 0.20 THR 225 -0.16 VAL 339

GLY 334 0.21 TYR 226 -0.22 VAL 339

GLY 334 0.20 MET 227 -0.29 ALA 291

GLY 334 0.19 PRO 228 -0.20 ALA 291

GLY 334 0.22 SER 229 -0.17 VAL 339

GLY 334 0.22 ILE 230 -0.23 ASN 332

GLY 334 0.20 LEU 231 -0.27 ALA 295

GLY 334 0.20 ILE 232 -0.19 LEU 259

GLY 334 0.23 THR 233 -0.18 PHE 336

GLY 334 0.21 ILE 234 -0.24 PRO 325

GLY 334 0.18 LEU 235 -0.28 VAL 260

GLY 334 0.20 SER 236 -0.18 THR 256

GLY 334 0.20 TRP 237 -0.17 VAL 260

GLY 334 0.16 VAL 238 -0.22 THR 256

GLY 334 0.16 SER 239 -0.19 ALA 252

GLY 334 0.16 PHE 240 -0.16 ALA 252

GLY 334 0.15 TRP 241 -0.19 ILE 322

GLY 334 0.13 ILE 242 -0.18 ALA 248

GLY 334 0.11 ASN 243 -0.15 ALA 248

ARG 323 0.11 TYR 244 -0.14 ALA 248

GLU 250 0.15 ASP 245 -0.13 ALA 249

VAL 252 0.21 ALA 246 -0.19 ALA 248

VAL 252 0.19 SER 247 -0.19 ALA 249

VAL 252 0.25 ALA 248 -0.25 ALA 249

VAL 252 0.20 ALA 249 -0.29 ALA 248

LEU 247 0.14 ARG 250 -0.20 ALA 252

LEU 247 0.17 VAL 251 -0.19 ALA 252

THR 256 0.21 ALA 252 -0.27 ALA 252

GLY 334 0.14 LEU 253 -0.24 ALA 252

GLY 334 0.17 GLY 254 -0.19 THR 256

LEU 240 0.19 ILE 255 -0.21 THR 256

VAL 260 0.17 THR 256 -0.26 THR 256

GLY 334 0.18 THR 257 -0.21 THR 256

MET 236 0.21 VAL 258 -0.19 LEU 259

THR 237 0.21 LEU 259 -0.22 LEU 259

MET 236 0.19 THR 260 -0.24 LEU 259

MET 236 0.24 MET 261 -0.18 LEU 259

PRO 233 0.26 THR 262 -0.18 THR 263

PRO 233 0.20 THR 263 -0.23 THR 263

PRO 233 0.20 ILE 264 -0.19 THR 263

PRO 233 0.26 ASN 265 -0.16 THR 263

PRO 233 0.25 THR 266 -0.17 HIS 267

PRO 233 0.19 HIS 267 -0.19 HIS 267

PRO 233 0.15 LEU 268 -0.13 HIS 267

GLN 229 0.17 ARG 269 -0.11 PRO 228

SER 272 0.15 GLU 270 -0.12 GLN 224

ASN 275 0.15 THR 271 -0.11 GLN 224

LEU 345 0.16 LEU 272 -0.10 GLN 224

LEU 345 0.15 PRO 273 -0.09 GLN 224

LEU 345 0.17 LYS 274 -0.09 PRO 228

LEU 345 0.24 ILE 275 -0.08 PRO 228

LEU 345 0.34 PRO 276 -0.09 ARG 312

GLY 224 0.46 TYR 277 -0.11 VAL 339

LEU 345 0.39 VAL 278 -0.13 VAL 339

LEU 345 0.32 LYS 279 -0.15 THR 343

LEU 345 0.30 ALA 280 -0.19 THR 343

LEU 338 0.27 ILE 281 -0.18 VAL 339

ILE 228 0.32 ASP 282 -0.14 VAL 339

LEU 338 0.35 MET 283 -0.18 VAL 339

LEU 338 0.32 TYR 284 -0.20 VAL 339

GLY 334 0.30 LEU 285 -0.16 VAL 339

GLY 334 0.36 MET 286 -0.14 VAL 339

GLY 334 0.36 GLY 287 -0.18 VAL 339

GLY 334 0.30 CYS 288 -0.17 VAL 339

GLY 334 0.31 PHE 289 -0.13 THR 263

GLY 334 0.39 VAL 290 -0.13 VAL 339

GLY 334 0.33 PHE 291 -0.16 VAL 339

GLY 334 0.27 VAL 292 -0.15 LEU 259

GLY 334 0.32 PHE 293 -0.11 LEU 259

GLY 334 0.35 MET 294 -0.12 ARG 312

GLY 334 0.24 ALA 295 -0.15 THR 256

GLY 334 0.22 LEU 296 -0.15 THR 256

ILE 327 0.28 LEU 297 -0.12 THR 256

ILE 327 0.24 GLU 298 -0.12 THR 256

TRP 246 0.21 TYR 299 -0.13 ALA 252

TRP 246 0.34 ALA 300 -0.12 LEU 235

ARG 323 0.26 LEU 301 -0.10 LEU 235

ARG 323 0.19 VAL 302 -0.10 LEU 235

ALA 319 0.16 ASN 303 -0.10 LEU 235

ALA 319 0.22 TYR 304 -0.12 VAL 243

ALA 319 0.20 ILE 305 -0.10 VAL 243

PRO 315 0.15 PHE 306 -0.08 ILE 322

PRO 315 0.18 PHE 307 -0.07 ILE 322

PRO 315 0.21 SER 308 -0.07 VAL 243

ALA 316 0.17 GLN 309 -0.08 PRO 233

ALA 316 0.13 PRO 310 -0.10 ALA 314

ALA 316 0.13 ALA 311 -0.13 ALA 315

ALA 316 0.15 ARG 312 -0.12 MET 294

ALA 319 0.15 ALA 313 -0.11 ARG 312

ARG 323 0.12 ALA 314 -0.11 ALA 252

ARG 323 0.16 ALA 315 -0.13 VAL 339

ARG 323 0.21 ILE 316 -0.13 VAL 339

ILE 327 0.17 ASP 317 -0.12 VAL 339

GLY 334 0.17 ARG 318 -0.18 THR 306

ILE 327 0.22 TRP 319 -0.19 VAL 339

GLY 334 0.24 SER 320 -0.18 VAL 339

GLY 334 0.21 ARG 321 -0.24 THR 306

GLY 334 0.25 ILE 322 -0.33 THR 306

GLY 334 0.31 PHE 323 -0.27 VAL 339

GLY 334 0.30 PHE 324 -0.24 PHE 336

GLY 334 0.28 PRO 325 -0.33 ALA 295

GLY 334 0.33 VAL 326 -0.36 PHE 336

GLY 334 0.39 VAL 327 -0.31 VAL 339

GLY 334 0.36 PHE 328 -0.32 VAL 339

GLY 334 0.34 SER 329 -0.41 VAL 339

GLY 334 0.40 PHE 330 -0.39 VAL 339

GLY 334 0.44 PHE 331 -0.34 VAL 339

LEU 338 0.36 ASN 332 -0.40 VAL 339

LEU 338 0.38 ILE 333 -0.45 VAL 339

LEU 338 0.44 VAL 334 -0.38 VAL 339

LEU 338 0.40 TYR 335 -0.35 VAL 339

LEU 338 0.35 TRP 336 -0.42 VAL 339

LEU 338 0.38 LEU 337 -0.43 THR 343

ALA 342 0.42 TYR 338 -0.36 THR 343

LEU 345 0.37 TYR 339 -0.35 THR 343

ALA 342 0.33 VAL 340 -0.43 THR 343

LYS 70 0.25 ASP 10 -0.04 GLY 22

LYS 70 0.18 ASN 11 -0.04 GLY 22

LYS 70 0.16 THR 12 -0.05 GLY 22

ARG 71 0.17 THR 13 -0.05 GLY 22

ARG 71 0.12 VAL 14 -0.05 LYS 21

ARG 71 0.10 PHE 15 -0.06 GLY 22

ARG 71 0.11 THR 16 -0.06 GLY 22

GLY 22 0.12 ARG 17 -0.06 LYS 21

GLY 22 0.08 ILE 18 -0.06 LYS 21

GLY 22 0.10 LEU 19 -0.07 LYS 21

GLY 22 0.15 ASP 20 -0.07 LYS 21

GLY 22 0.11 ARG 21 -0.07 GLU 14

GLY 22 0.09 LEU 22 -0.07 LYS 21

GLY 22 0.11 LEU 23 -0.08 LYS 21

GLY 22 0.12 ASP 24 -0.08 GLU 14

GLY 22 0.10 GLY 25 -0.09 GLU 14

GLY 22 0.09 TYR 26 -0.08 ASP 17

GLY 22 0.08 ASP 27 -0.09 ASP 17

GLY 22 0.08 ASN 28 -0.08 LYS 21

GLY 22 0.07 ARG 29 -0.08 LYS 21

GLY 22 0.07 LEU 30 -0.07 ASP 17

GLY 22 0.06 ARG 31 -0.07 VAL 340

GLY 22 0.06 PRO 32 -0.07 GLY 25

GLY 22 0.05 GLY 33 -0.10 GLY 25

GLY 22 0.06 LEU 34 -0.11 GLY 25

GLY 22 0.05 GLY 35 -0.13 GLY 25

GLY 22 0.05 GLU 36 -0.11 GLY 25

TYR 338 0.05 ARG 37 -0.10 GLY 25

TYR 338 0.06 VAL 38 -0.09 VAL 340

TYR 338 0.06 THR 39 -0.08 VAL 340

TYR 356 0.06 GLU 40 -0.08 VAL 340

TYR 356 0.07 VAL 41 -0.08 VAL 106

TYR 356 0.08 LYS 42 -0.08 VAL 106

TYR 356 0.08 THR 43 -0.08 VAL 106

TYR 356 0.09 ASP 44 -0.09 THR 132

TYR 356 0.10 ILE 45 -0.10 LYS 102

ASN 346 0.12 PHE 46 -0.10 LYS 102

ASN 346 0.13 VAL 47 -0.11 LYS 102

ASN 346 0.14 THR 48 -0.12 LYS 102

ASN 346 0.15 SER 49 -0.11 THR 133

ASN 346 0.15 PHE 50 -0.10 THR 133

ASN 346 0.14 GLY 51 -0.13 ASN 54

LEU 345 0.14 PRO 52 -0.16 ASN 54

LEU 355 0.14 VAL 53 -0.12 ASN 54

LEU 355 0.14 SER 54 -0.12 ASN 54

LEU 355 0.16 ASP 55 -0.13 LYS 285

LEU 355 0.16 HIS 56 -0.15 LYS 285

LEU 355 0.14 ASP 57 -0.13 VAL 340

LEU 355 0.16 MET 58 -0.13 VAL 340

LEU 355 0.13 GLU 59 -0.12 VAL 340

LEU 355 0.13 TYR 60 -0.11 ASN 54

LEU 355 0.11 THR 61 -0.13 THR 133

ASN 346 0.11 ILE 62 -0.16 LYS 102

VAL 64 0.12 ASP 63 -0.21 LYS 102

ASP 63 0.12 VAL 64 -0.13 LYS 102

ASN 346 0.10 PHE 65 -0.10 THR 132

TYR 356 0.09 PHE 66 -0.10 THR 132

TYR 356 0.08 ARG 67 -0.08 VAL 106

TYR 356 0.07 GLN 68 -0.08 VAL 106

TYR 356 0.07 SER 69 -0.07 VAL 106

TYR 338 0.06 TRP 70 -0.07 VAL 106

TYR 338 0.06 LYS 71 -0.06 VAL 340

TYR 338 0.05 ASP 72 -0.06 LYS 21

GLY 22 0.06 GLU 73 -0.07 GLY 25

GLY 22 0.07 ARG 74 -0.07 GLU 14

GLY 22 0.07 LEU 75 -0.07 LYS 21

GLY 22 0.06 LYS 76 -0.06 LYS 21

PRO 34 0.06 PHE 77 -0.06 LYS 21

PRO 34 0.07 LYS 78 -0.06 GLU 14

PRO 34 0.09 GLY 79 -0.05 LYS 21

PRO 34 0.12 PRO 80 -0.05 LYS 21

PRO 34 0.11 MET 81 -0.05 GLY 22

ASN 346 0.07 THR 82 -0.05 GLY 22

ASN 346 0.08 VAL 83 -0.05 GLY 22

ASN 346 0.07 LEU 84 -0.06 GLY 22

ASN 346 0.08 ARG 85 -0.06 GLY 22

ASN 346 0.08 LEU 86 -0.06 GLY 22

ASN 346 0.08 ASN 87 -0.07 GLY 22

ASN 346 0.08 ASN 88 -0.07 GLY 22

ASP 24 0.08 LEU 89 -0.08 GLY 22

ASP 24 0.07 MET 90 -0.08 GLY 22

GLY 22 0.06 ALA 91 -0.08 VAL 106

GLY 22 0.07 SER 92 -0.08 GLY 22

GLY 22 0.09 LYS 93 -0.08 LYS 21

GLY 22 0.08 ILE 94 -0.08 LYS 21

GLY 22 0.07 TRP 95 -0.08 VAL 106

TYR 356 0.06 THR 96 -0.09 VAL 106

TYR 356 0.06 PRO 97 -0.10 VAL 106

TYR 356 0.06 ASP 98 -0.11 VAL 106

TYR 356 0.07 THR 99 -0.12 VAL 106

TYR 356 0.08 PHE 100 -0.11 PHE 105

TYR 356 0.09 PHE 101 -0.11 LYS 103

TYR 356 0.10 HIS 102 -0.12 VAL 340

TYR 356 0.12 ASN 103 -0.12 VAL 340

TYR 356 0.10 GLY 104 -0.13 LYS 106

TYR 356 0.10 LYS 105 -0.14 LYS 106

THR 146 0.09 LYS 106 -0.16 LYS 106

LEU 355 0.08 SER 107 -0.18 LYS 103

ALA 109 0.14 VAL 108 -0.22 LYS 103

VAL 108 0.14 ALA 109 -0.14 THR 125

LEU 345 0.09 HIS 110 -0.14 VAL 106

LEU 345 0.08 ASN 111 -0.16 VAL 106

LEU 345 0.10 MET 112 -0.13 VAL 106

LEU 345 0.09 THR 113 -0.13 LEU 128

LEU 345 0.08 MET 114 -0.09 LEU 128

LEU 345 0.08 PRO 115 -0.09 VAL 106

ASN 346 0.09 ASN 116 -0.08 MET 131

ASN 346 0.08 LYS 117 -0.08 TYR 129

ASN 346 0.08 LEU 118 -0.08 ASP 95

ASN 346 0.07 LEU 119 -0.06 ASP 95

ASN 346 0.07 ARG 120 -0.06 GLY 22

ASN 346 0.06 ILE 121 -0.06 GLY 22

TYR 338 0.07 THR 122 -0.06 GLY 22

TYR 338 0.06 GLU 123 -0.06 LYS 21

TYR 338 0.07 ASP 124 -0.06 LYS 21

TYR 338 0.06 GLY 125 -0.06 LYS 21

TYR 338 0.07 THR 126 -0.06 LYS 21

TYR 356 0.06 LEU 127 -0.06 GLY 22

TYR 356 0.07 LEU 128 -0.06 VAL 106

TYR 356 0.07 TYR 129 -0.08 LYS 117

ASN 346 0.07 THR 130 -0.08 VAL 106

ASN 346 0.08 MET 131 -0.10 VAL 106

ASN 346 0.09 ARG 132 -0.11 THR 132

LEU 345 0.09 LEU 133 -0.14 LYS 103

LEU 345 0.10 THR 134 -0.19 LYS 103

TYR 356 0.10 VAL 135 -0.15 LYS 103

LEU 355 0.10 ARG 136 -0.16 LYS 103

TYR 356 0.12 ALA 137 -0.13 LYS 103

TYR 356 0.13 GLU 138 -0.12 VAL 340

TYR 356 0.15 CYS 139 -0.12 VAL 340

TYR 356 0.17 PRO 140 -0.14 VAL 340

TYR 356 0.18 MET 141 -0.14 VAL 340

TYR 356 0.21 HIS 142 -0.15 VAL 340

LEU 355 0.20 LEU 143 -0.15 VAL 340

TYR 356 0.22 GLU 144 -0.19 ARG 347

TYR 338 0.18 ASP 145 -0.14 ILE 333

LEU 355 0.18 PHE 146 -0.13 LEU 223

TYR 277 0.20 PRO 147 -0.12 LEU 223

TYR 338 0.23 MET 148 -0.11 LEU 223

TYR 338 0.19 ASP 149 -0.12 LEU 223

TYR 338 0.18 ALA 150 -0.11 VAL 340

TYR 356 0.16 HIS 151 -0.12 VAL 340

TYR 356 0.15 ALA 152 -0.12 VAL 340

TYR 356 0.15 CYS 153 -0.12 VAL 340

TYR 356 0.14 PRO 154 -0.12 VAL 340

TYR 356 0.12 LEU 155 -0.12 LYS 103

TYR 356 0.11 LYS 156 -0.11 VAL 340

TYR 356 0.10 PHE 157 -0.10 LYS 103

TYR 356 0.09 GLY 158 -0.10 VAL 340

TYR 356 0.07 SER 159 -0.10 VAL 340

TYR 356 0.07 TYR 160 -0.10 VAL 340

TYR 356 0.05 ALA 161 -0.10 VAL 340

TYR 356 0.06 TYR 162 -0.10 VAL 340

TYR 356 0.06 THR 163 -0.11 VAL 340

TYR 356 0.06 ARG 164 -0.11 VAL 340

TYR 338 0.05 ALA 165 -0.10 VAL 340

TYR 356 0.05 GLU 166 -0.10 VAL 340

TYR 356 0.06 VAL 167 -0.09 VAL 340

TYR 356 0.07 VAL 168 -0.09 VAL 340

TYR 356 0.08 TYR 169 -0.09 VAL 340

TYR 356 0.08 GLU 170 -0.09 VAL 340

TYR 356 0.09 TRP 171 -0.08 VAL 340

TYR 356 0.08 THR 172 -0.07 THR 132

TYR 338 0.09 ARG 173 -0.07 VAL 340

TYR 338 0.10 GLU 174 -0.08 VAL 340

TYR 338 0.10 PRO 175 -0.08 VAL 340

TYR 338 0.12 ALA 176 -0.08 VAL 340

TYR 338 0.11 ARG 177 -0.07 VAL 340

TYR 338 0.10 SER 178 -0.08 LYS 102

TYR 356 0.10 VAL 179 -0.09 LYS 102

ASN 346 0.13 VAL 180 -0.09 LYS 102

ASN 346 0.15 VAL 181 -0.07 LYS 102

ASN 346 0.17 ALA 182 -0.07 ARG 347

ASN 346 0.21 GLU 183 -0.08 ARG 347

ASN 346 0.21 ASP 184 -0.09 ARG 347

ASN 346 0.18 GLY 185 -0.08 ARG 347

ASN 346 0.19 SER 186 -0.07 ARG 347

ASN 346 0.17 ARG 187 -0.09 ASN 54

LEU 345 0.19 LEU 188 -0.07 GLN 224

LEU 345 0.22 ASN 189 -0.07 GLN 224

LEU 345 0.22 GLN 190 -0.10 GLN 224

LEU 345 0.21 TYR 191 -0.10 LEU 223

ASN 346 0.26 ASP 192 -0.09 LEU 223

ARG 347 0.21 LEU 193 -0.09 LEU 223

ARG 347 0.24 LEU 194 -0.08 LEU 223

ARG 347 0.17 GLY 195 -0.08 LEU 223

TYR 338 0.13 GLN 196 -0.09 VAL 340

TYR 356 0.13 THR 197 -0.09 VAL 340

TYR 356 0.12 VAL 198 -0.10 VAL 340

TYR 356 0.11 ASP 199 -0.11 VAL 340

TYR 356 0.10 SER 200 -0.11 VAL 340

TYR 356 0.10 GLY 201 -0.12 VAL 340

TYR 356 0.09 ILE 202 -0.12 VAL 340

TYR 356 0.09 VAL 203 -0.13 VAL 340

TYR 356 0.08 GLN 204 -0.14 GLY 191

TYR 356 0.07 SER 205 -0.14 VAL 340

TYR 356 0.06 SER 206 -0.15 TYR 58

TYR 356 0.05 THR 207 -0.13 VAL 340

TYR 356 0.06 GLY 208 -0.13 VAL 340

TYR 356 0.07 GLU 209 -0.12 VAL 340

TYR 356 0.07 TYR 210 -0.12 VAL 340

TYR 356 0.08 VAL 211 -0.11 VAL 340

TYR 356 0.09 VAL 212 -0.11 VAL 340

TYR 356 0.10 MET 213 -0.10 VAL 340

TYR 356 0.11 THR 214 -0.11 VAL 340

TYR 356 0.12 THR 215 -0.10 VAL 340

TYR 356 0.13 HIS 216 -0.11 VAL 340

TYR 356 0.13 PHE 217 -0.10 VAL 340

TYR 338 0.15 HIS 218 -0.10 VAL 340

ARG 347 0.18 LEU 219 -0.10 LEU 223

ARG 347 0.27 LYS 220 -0.10 LEU 223

ARG 347 0.24 ARG 221 -0.10 LEU 223

LEU 345 0.33 LYS 222 -0.09 LEU 223

LEU 345 0.37 ILE 223 -0.10 PRO 228

TYR 277 0.46 GLY 224 -0.09 LEU 231

TYR 277 0.26 TYR 225 -0.10 PRO 228

TYR 277 0.23 PHE 226 -0.11 PRO 228

VAL 278 0.30 VAL 227 -0.10 LEU 231

ASP 282 0.32 ILE 228 -0.10 LEU 231

ASP 282 0.17 GLN 229 -0.11 LEU 231

TYR 338 0.17 THR 230 -0.12 LEU 231

VAL 334 0.22 TYR 231 -0.11 LEU 231

MET 286 0.29 LEU 232 -0.10 LEU 231

THR 262 0.26 PRO 233 -0.11 LEU 231

PHE 331 0.21 CYS 234 -0.11 LEU 231

PHE 331 0.28 ILE 235 -0.11 LEU 231

PHE 289 0.30 MET 236 -0.10 LEU 231

THR 262 0.22 THR 237 -0.12 LEU 231

PHE 331 0.22 VAL 238 -0.12 LEU 231

PHE 293 0.28 ILE 239 -0.10 LEU 231

PHE 293 0.26 LEU 240 -0.11 LEU 231

PHE 331 0.18 SER 241 -0.13 PRO 325

PHE 293 0.22 GLN 242 -0.12 PRO 325

PHE 293 0.27 VAL 243 -0.12 TYR 304

PHE 293 0.21 SER 244 -0.13 ILE 322

LEU 297 0.22 PHE 245 -0.13 ILE 322

ALA 300 0.34 TRP 246 -0.11 ILE 322

ALA 300 0.27 LEU 247 -0.11 ILE 322

ALA 300 0.17 ASN 248 -0.11 ILE 322

THR 311 0.15 ARG 249 -0.13 ILE 322

SER 251 0.18 GLU 250 -0.13 ILE 322

SER 251 0.21 SER 251 -0.13 ILE 322

PRO 253 0.19 VAL 252 -0.16 ILE 322

PRO 253 0.26 PRO 253 -0.16 ILE 322

PRO 253 0.25 ALA 254 -0.13 ILE 322

PRO 253 0.19 ARG 255 -0.14 ILE 322

PRO 253 0.19 THR 256 -0.16 ILE 322

VAL 257 0.24 VAL 257 -0.16 LEU 235

VAL 257 0.19 PHE 258 -0.13 LEU 235

VAL 257 0.16 GLY 259 -0.15 PRO 325

VAL 257 0.17 VAL 260 -0.16 PRO 325

THR 261 0.21 THR 261 -0.15 LEU 235

LEU 264 0.17 THR 262 -0.14 LEU 231

GLY 334 0.15 VAL 263 -0.16 LEU 231

THR 237 0.17 LEU 264 -0.18 LEU 231

THR 265 0.19 THR 265 -0.15 LEU 231

THR 265 0.15 MET 266 -0.15 LEU 231

PRO 243 0.17 THR 267 -0.17 LEU 231

PRO 233 0.18 THR 268 -0.16 LEU 231

THR 268 0.16 LEU 269 -0.14 LEU 231

LEU 355 0.17 SER 270 -0.14 LEU 231

LEU 355 0.15 ILE 271 -0.16 PRO 228

PRO 233 0.15 SER 272 -0.15 PRO 228

LEU 355 0.16 ALA 273 -0.13 PRO 228

LEU 355 0.18 ARG 274 -0.15 ILE 282

LEU 355 0.16 ASN 275 -0.18 ILE 282

LEU 355 0.15 SER 276 -0.15 LYS 285

LEU 355 0.18 LEU 277 -0.15 LYS 285

LEU 355 0.18 PRO 278 -0.18 LYS 285

LEU 355 0.21 LYS 279 -0.20 LYS 285

LEU 355 0.25 VAL 280 -0.17 VAL 340

LEU 355 0.31 ALA 281 -0.19 VAL 340

LEU 355 0.28 TYR 282 -0.18 VAL 340

LEU 355 0.24 ALA 283 -0.18 THR 343

LEU 355 0.21 THR 284 -0.15 ILE 333

TYR 338 0.19 ALA 285 -0.14 ILE 333

TYR 338 0.19 MET 286 -0.15 LEU 223

LEU 355 0.19 ASP 287 -0.17 LEU 223

LEU 355 0.18 TRP 288 -0.19 TYR 340

VAL 334 0.21 PHE 289 -0.14 ILE 333

PHE 331 0.17 ILE 290 -0.16 LEU 231

LEU 355 0.19 ALA 291 -0.17 SER 329

PHE 331 0.20 VAL 292 -0.21 PHE 336

PHE 331 0.21 CYS 293 -0.15 LEU 231

PHE 331 0.16 TYR 294 -0.17 LEU 231

PHE 331 0.17 ALA 295 -0.18 SER 329

PHE 331 0.21 PHE 296 -0.16 SER 329

PHE 331 0.18 VAL 297 -0.16 PRO 325

PHE 331 0.15 PHE 298 -0.17 SER 329

PHE 331 0.17 SER 299 -0.17 SER 329

PHE 331 0.18 ALA 300 -0.16 ILE 322

PHE 331 0.14 LEU 301 -0.17 PRO 325

CYS 344 0.14 ILE 302 -0.19 ILE 322

PHE 331 0.16 GLU 303 -0.17 ILE 322

PHE 331 0.15 PHE 304 -0.18 ILE 322

GLY 334 0.13 ALA 305 -0.20 ILE 322

PHE 331 0.13 THR 306 -0.20 ILE 322

VAL 327 0.15 VAL 307 -0.18 ILE 322

ARG 249 0.15 ASN 308 -0.20 ILE 322

GLY 334 0.12 TYR 309 -0.22 ILE 322

SER 308 0.13 PHE 310 -0.20 ILE 322

SER 308 0.16 THR 311 -0.19 ILE 322

SER 308 0.19 LYS 312 -0.19 ILE 322

SER 308 0.17 SER 313 -0.20 ILE 322

SER 308 0.18 GLN 314 -0.18 ILE 322

SER 308 0.21 PRO 315 -0.17 ILE 322

SER 308 0.20 ALA 316 -0.15 ILE 322

VAL 327 0.17 ARG 317 -0.17 ILE 322

VAL 327 0.16 ALA 318 -0.17 ILE 322

TYR 304 0.22 ALA 319 -0.15 ILE 322

VAL 327 0.21 LYS 320 -0.15 ILE 322

VAL 327 0.20 ILE 321 -0.16 ILE 322

VAL 327 0.21 ASP 322 -0.15 ILE 322

LEU 301 0.26 ARG 323 -0.13 ILE 322

VAL 327 0.25 LEU 324 -0.14 ILE 322

VAL 327 0.23 SER 325 -0.16 ILE 322

VAL 327 0.27 ARG 326 -0.12 ILE 322

VAL 327 0.32 ILE 327 -0.12 ILE 322

PHE 331 0.29 ALA 328 -0.14 ILE 322

PHE 331 0.28 PHE 329 -0.14 PRO 325

PHE 331 0.35 PRO 330 -0.11 PRO 325

PHE 331 0.36 LEU 331 -0.12 SER 329

PHE 331 0.31 LEU 332 -0.14 SER 329

PHE 331 0.33 PHE 333 -0.13 SER 329

PHE 331 0.44 GLY 334 -0.12 LEU 332

PHE 331 0.40 ILE 335 -0.14 VAL 292

PHE 331 0.34 PHE 336 -0.21 VAL 292

PHE 331 0.39 ASN 337 -0.12 VAL 292

VAL 334 0.44 LEU 338 -0.11 SER 329

VAL 334 0.38 VAL 339 -0.17 ILE 242

VAL 334 0.33 TYR 340 -0.19 TRP 288

TYR 338 0.40 TRP 341 -0.12 ALA 285

TYR 338 0.42 ALA 342 -0.13 ILE 238

TYR 338 0.35 THR 343 -0.18 ALA 283

TYR 338 0.34 TYR 344 -0.16 GLU 144

TYR 277 0.42 LEU 345 -0.14 GLU 144

TYR 338 0.41 ASN 346 -0.14 GLU 144

TYR 338 0.34 ARG 347 -0.19 GLU 144

GLY 22 0.09 GLY 25 -0.13 GLY 35

GLY 22 0.09 ASP 26 -0.13 GLY 35

GLY 22 0.08 VAL 27 -0.11 GLY 35

GLY 22 0.09 THR 28 -0.08 LEU 34

GLY 22 0.09 VAL 29 -0.08 GLY 35

GLY 22 0.08 ILE 30 -0.07 GLY 35

GLY 22 0.08 LEU 31 -0.07 SER 10

GLY 22 0.09 ASN 32 -0.08 SER 10

LYS 21 0.09 ASN 33 -0.08 SER 10

LYS 21 0.07 LEU 34 -0.07 SER 10

LYS 21 0.07 LEU 35 -0.07 SER 10

GLU 14 0.07 GLU 36 -0.09 SER 10

GLU 14 0.06 GLY 37 -0.12 SER 10

GLU 14 0.06 TYR 38 -0.09 LYS 13

LEU 345 0.06 ASP 39 -0.09 LYS 13

LEU 345 0.06 ASN 40 -0.12 ILE 106

LEU 345 0.07 LYS 41 -0.08 LYS 105

LEU 345 0.07 LEU 42 -0.07 ASP 10

LEU 345 0.08 ARG 43 -0.07 VAL 340

LEU 345 0.07 PRO 44 -0.07 VAL 340

LEU 345 0.08 ASP 45 -0.06 VAL 340

LEU 345 0.08 ILE 46 -0.06 ASP 10

ASN 8 0.09 GLY 47 -0.06 LEU 79

LEU 345 0.08 VAL 48 -0.06 LEU 337

LEU 345 0.09 LYS 49 -0.07 LEU 337

LEU 345 0.09 PRO 50 -0.08 VAL 340

LEU 345 0.08 THR 51 -0.09 VAL 340

LEU 345 0.08 LEU 52 -0.10 VAL 340

LEU 345 0.08 ILE 53 -0.11 VAL 340

LEU 345 0.08 HIS 54 -0.12 VAL 340

LEU 345 0.08 THR 55 -0.13 VAL 340

LEU 345 0.07 ASP 56 -0.13 VAL 340

LEU 345 0.07 MET 57 -0.14 VAL 340

LEU 357 0.09 TYR 58 -0.15 SER 206

LEU 357 0.10 VAL 59 -0.15 VAL 340

TYR 356 0.12 ASN 60 -0.14 VAL 340

TYR 356 0.14 SER 61 -0.15 VAL 340

TYR 356 0.13 ILE 62 -0.16 VAL 340

TYR 356 0.12 GLY 63 -0.16 VAL 340

LEU 355 0.13 PRO 64 -0.17 VAL 340

LEU 345 0.11 VAL 65 -0.19 VAL 340

LEU 345 0.12 ASN 66 -0.20 VAL 340

LEU 345 0.14 ALA 67 -0.23 VAL 340

LEU 345 0.15 ILE 68 -0.26 PRO 288

LEU 345 0.14 ASN 69 -0.20 VAL 340

LEU 345 0.14 MET 70 -0.23 VAL 340

LEU 345 0.13 GLU 71 -0.20 VAL 340

LEU 345 0.11 TYR 72 -0.18 VAL 340

LEU 345 0.09 THR 73 -0.16 VAL 340

LEU 345 0.09 ILE 74 -0.15 VAL 340

TYR 356 0.09 ASP 75 -0.14 VAL 340

TYR 356 0.08 ILE 76 -0.13 VAL 340

TYR 356 0.07 PHE 77 -0.12 VAL 340

LEU 345 0.07 PHE 78 -0.12 VAL 340

THR 142 0.14 ALA 79 -0.13 VAL 340

LEU 345 0.07 GLN 80 -0.12 VAL 340

LEU 345 0.06 THR 81 -0.11 VAL 340

LEU 345 0.07 TRP 82 -0.10 VAL 340

LEU 345 0.06 TYR 83 -0.09 VAL 340

LEU 345 0.06 ASP 84 -0.08 VAL 340

LEU 345 0.06 ARG 85 -0.07 VAL 340

LEU 345 0.06 ARG 86 -0.06 VAL 340

GLY 22 0.06 LEU 87 -0.07 VAL 340

GLY 22 0.06 LYS 88 -0.07 VAL 340

GLY 22 0.07 PHE 89 -0.07 VAL 340

GLY 22 0.07 ASN 90 -0.07 VAL 340

GLY 22 0.07 SER 91 -0.07 VAL 340

GLY 22 0.07 THR 92 -0.08 VAL 340

GLY 22 0.07 ILE 93 -0.09 VAL 340

GLY 22 0.06 LYS 94 -0.10 VAL 340

GLY 22 0.06 VAL 95 -0.10 VAL 340

GLY 22 0.07 LEU 96 -0.09 VAL 340

GLY 22 0.06 ARG 97 -0.09 VAL 340

GLY 22 0.06 LEU 98 -0.09 VAL 340

GLY 22 0.06 ASN 99 -0.09 GLY 108

GLY 22 0.06 SER 100 -0.10 GLY 108

GLY 22 0.07 ASN 101 -0.09 GLY 108

GLY 22 0.07 MET 102 -0.08 LYS 21

GLY 22 0.06 VAL 103 -0.09 ASP 89

GLY 22 0.07 GLY 104 -0.11 ASP 89

GLY 22 0.07 LYS 105 -0.11 ASN 40

GLY 22 0.07 ILE 106 -0.12 ASN 40

LEU 345 0.06 TRP 107 -0.07 VAL 340

LEU 345 0.07 ILE 108 -0.08 VAL 340

LEU 345 0.08 PRO 109 -0.09 VAL 340

LEU 345 0.09 ASP 110 -0.09 VAL 340

LEU 345 0.09 THR 111 -0.10 VAL 340

LEU 345 0.10 PHE 112 -0.11 VAL 340

LEU 345 0.11 PHE 113 -0.13 VAL 340

LEU 345 0.12 ARG 114 -0.14 VAL 340

LEU 345 0.13 ASN 115 -0.16 VAL 340

LEU 345 0.12 SER 116 -0.15 VAL 340

LEU 345 0.12 LYS 117 -0.15 VAL 340

LEU 345 0.10 LYS 118 -0.13 PHE 105

LEU 345 0.09 ALA 119 -0.13 PHE 105

LEU 345 0.07 ASP 120 -0.13 VAL 108

GLY 22 0.06 ALA 121 -0.13 VAL 108

GLY 22 0.06 HIS 122 -0.13 VAL 108

ASP 24 0.06 TRP 123 -0.14 GLY 108

TYR 356 0.07 ILE 124 -0.15 PHE 105

TYR 356 0.07 THR 125 -0.14 VAL 106

TYR 356 0.06 THR 126 -0.13 VAL 106

TRP 123 0.06 PRO 127 -0.12 GLY 108

TYR 356 0.06 ASN 128 -0.11 VAL 108

GLY 22 0.05 ARG 129 -0.10 VAL 108

GLY 22 0.05 MET 130 -0.10 VAL 340

GLY 22 0.06 LEU 131 -0.10 VAL 340

GLY 22 0.05 ARG 132 -0.10 VAL 340

GLY 22 0.06 ILE 133 -0.09 VAL 340

GLY 22 0.06 TRP 134 -0.09 VAL 340

GLY 22 0.06 ASN 135 -0.09 VAL 340

GLY 22 0.06 ASP 136 -0.09 VAL 340

GLY 22 0.06 GLY 137 -0.09 VAL 340

GLY 22 0.06 ARG 138 -0.10 VAL 340

GLY 22 0.06 VAL 139 -0.10 VAL 340

GLY 22 0.05 LEU 140 -0.11 VAL 340

GLY 22 0.05 TYR 141 -0.11 VAL 340

ALA 79 0.14 THR 142 -0.11 VAL 340

LEU 345 0.05 LEU 143 -0.11 VAL 340

TYR 356 0.06 ARG 144 -0.11 VAL 340

LYS 106 0.07 LEU 145 -0.12 VAL 340

LYS 106 0.09 THR 146 -0.13 VAL 340

LEU 345 0.09 ILE 147 -0.14 VAL 340

LEU 345 0.10 ASP 148 -0.16 VAL 340

LEU 345 0.11 ALA 149 -0.17 VAL 340

LEU 345 0.13 GLU 150 -0.19 VAL 340

LEU 345 0.14 CYS 151 -0.20 VAL 340

LEU 345 0.15 GLN 152 -0.24 VAL 340

LEU 345 0.15 LEU 153 -0.26 VAL 340

LEU 345 0.15 GLN 154 -0.31 VAL 340

LEU 345 0.15 LEU 155 -0.31 VAL 340

LEU 345 0.15 HIS 156 -0.35 VAL 340

LEU 345 0.14 ASN 157 -0.32 VAL 340

LEU 345 0.15 PHE 158 -0.29 VAL 340

LEU 345 0.14 PRO 159 -0.25 VAL 340

LEU 357 0.26 MET 160 -0.26 VAL 340

LEU 345 0.14 ASP 161 -0.27 VAL 340

LEU 357 0.18 GLU 162 -0.25 VAL 340

LEU 345 0.13 HIS 163 -0.24 VAL 340

LEU 345 0.12 SER 164 -0.22 VAL 340

LEU 345 0.13 CYS 165 -0.21 VAL 340

LEU 345 0.12 PRO 166 -0.19 VAL 340

LEU 345 0.11 LEU 167 -0.17 VAL 340

LEU 345 0.11 GLU 168 -0.16 VAL 340

LEU 345 0.11 PHE 169 -0.13 VAL 340

LEU 345 0.11 SER 170 -0.12 VAL 340

LEU 345 0.10 SER 171 -0.10 VAL 340

LEU 345 0.11 TYR 172 -0.09 VAL 340

LEU 345 0.10 GLY 173 -0.08 MET 115

LEU 345 0.10 TYR 174 -0.08 VAL 340

LEU 345 0.11 PRO 175 -0.09 VAL 340

LEU 345 0.10 ARG 176 -0.09 VAL 340

LEU 345 0.10 GLU 177 -0.08 LEU 337

LEU 345 0.09 GLU 178 -0.08 VAL 340

LEU 345 0.09 ILE 179 -0.09 VAL 340

LEU 345 0.09 VAL 180 -0.11 VAL 340

LEU 345 0.09 TYR 181 -0.12 VAL 340

LEU 345 0.09 GLN 182 -0.13 VAL 340

LEU 345 0.08 TRP 183 -0.14 VAL 340

LEU 345 0.08 LYS 184 -0.13 VAL 340

LEU 345 0.07 ARG 185 -0.14 VAL 340

LEU 345 0.07 SER 186 -0.14 VAL 340

LEU 345 0.07 SER 187 -0.15 VAL 340

LEU 357 0.08 VAL 188 -0.15 VAL 340

LEU 357 0.11 GLU 189 -0.15 VAL 340

LEU 357 0.14 VAL 190 -0.16 VAL 340

TYR 356 0.15 GLY 191 -0.15 VAL 340

TYR 356 0.19 ASP 192 -0.15 VAL 340

TYR 356 0.20 THR 193 -0.16 VAL 340

TYR 356 0.23 ARG 194 -0.16 VAL 340

TYR 356 0.20 SER 195 -0.15 VAL 340

TYR 356 0.18 TRP 196 -0.16 VAL 340

TYR 356 0.16 ARG 197 -0.16 VAL 340

TYR 356 0.19 LEU 198 -0.18 VAL 340

LEU 355 0.21 TYR 199 -0.18 VAL 340

LEU 355 0.23 GLN 200 -0.20 VAL 340

LEU 357 0.23 PHE 201 -0.21 VAL 340

LEU 357 0.28 SER 202 -0.20 VAL 340

LEU 357 0.25 PHE 203 -0.19 VAL 340

LEU 357 0.29 VAL 204 -0.20 VAL 340

LEU 357 0.19 GLY 205 -0.19 VAL 340

LEU 357 0.13 LEU 206 -0.19 VAL 340

LEU 345 0.10 ARG 207 -0.18 VAL 340

LEU 345 0.10 ASN 208 -0.17 VAL 340

LEU 345 0.11 THR 209 -0.17 VAL 340

LEU 345 0.11 THR 210 -0.15 VAL 340

LEU 345 0.11 GLU 211 -0.15 VAL 340

LEU 345 0.12 VAL 212 -0.13 VAL 340

LEU 345 0.13 VAL 213 -0.13 VAL 340

LEU 345 0.13 LYS 214 -0.11 VAL 340

LEU 345 0.14 THR 215 -0.10 ALA 174

ASN 346 0.14 THR 216 -0.12 ARG 169

LEU 345 0.13 SER 217 -0.08 ARG 169

LEU 345 0.12 GLY 218 -0.08 LEU 337

LEU 345 0.12 ASP 219 -0.10 VAL 340

LEU 345 0.12 TYR 220 -0.11 VAL 340

LEU 345 0.11 VAL 221 -0.12 VAL 340

LEU 345 0.11 VAL 222 -0.14 VAL 340

LEU 345 0.10 MET 223 -0.15 VAL 340

LEU 345 0.11 SER 224 -0.17 VAL 340

LEU 345 0.10 VAL 225 -0.17 VAL 340

LEU 345 0.11 TYR 226 -0.19 VAL 340

LEU 345 0.10 PHE 227 -0.19 VAL 340

LEU 357 0.16 ASP 228 -0.21 VAL 340

LEU 357 0.20 LEU 229 -0.21 VAL 340

LEU 357 0.31 SER 230 -0.23 VAL 340

LEU 357 0.28 ARG 231 -0.23 VAL 340

LEU 355 0.38 ARG 232 -0.21 VAL 340

LEU 355 0.40 MET 233 -0.21 VAL 340

LEU 355 0.35 GLY 234 -0.19 VAL 340

LEU 355 0.26 TYR 235 -0.18 ILE 333

LEU 355 0.23 PHE 236 -0.20 ILE 333

LEU 355 0.30 THR 237 -0.20 ILE 333

LEU 355 0.25 ILE 238 -0.18 ILE 333

LEU 355 0.19 GLN 239 -0.18 ILE 333

GLY 334 0.16 THR 240 -0.21 ILE 333

TRP 351 0.20 TYR 241 -0.22 ILE 333

TRP 351 0.23 ILE 242 -0.20 ILE 333

GLY 334 0.18 PRO 243 -0.19 ILE 333

GLY 334 0.19 CYS 244 -0.22 ILE 333

GLY 334 0.18 THR 245 -0.23 ILE 333

GLY 334 0.18 LEU 246 -0.20 SER 329

GLY 334 0.19 ILE 247 -0.21 SER 329

GLY 334 0.19 VAL 248 -0.24 SER 329

GLY 334 0.18 VAL 249 -0.22 SER 329

GLY 334 0.19 LEU 250 -0.20 SER 329

GLY 334 0.20 SER 251 -0.24 SER 329

GLY 334 0.18 TRP 252 -0.24 SER 329

GLY 334 0.18 VAL 253 -0.21 SER 329

GLY 334 0.19 SER 254 -0.23 ILE 322

GLY 334 0.18 PHE 255 -0.25 ILE 322

GLY 334 0.16 TRP 256 -0.23 ILE 322

VAL 252 0.18 ILE 257 -0.23 ILE 322

SER 251 0.18 ASN 258 -0.24 ILE 322

GLY 334 0.17 LYS 259 -0.26 ILE 322

SER 251 0.20 ASP 260 -0.23 ILE 322

SER 251 0.23 ALA 261 -0.21 ILE 322

ALA 248 0.22 VAL 262 -0.23 ILE 322

ALA 254 0.28 PRO 263 -0.18 ILE 322

ALA 254 0.24 ALA 264 -0.19 ILE 322

GLY 334 0.20 ARG 265 -0.23 ILE 322

GLY 334 0.22 THR 266 -0.26 VAL 238

GLY 334 0.22 SER 267 -0.19 VAL 238

GLY 334 0.21 LEU 268 -0.18 PRO 325

GLY 334 0.22 GLY 269 -0.23 PRO 325

GLY 334 0.24 ILE 270 -0.26 LEU 235

GLY 334 0.23 THR 271 -0.17 LEU 235

GLY 334 0.21 THR 272 -0.20 LEU 231

GLY 334 0.23 VAL 273 -0.27 LEU 231

GLY 334 0.24 LEU 274 -0.19 LEU 231

GLY 334 0.21 THR 275 -0.18 LEU 231

GLY 334 0.21 MET 276 -0.23 LEU 231

GLY 334 0.22 THR 277 -0.26 PRO 228

PRO 233 0.23 THR 278 -0.18 PRO 228

PRO 233 0.19 LEU 279 -0.17 PRO 228

GLY 334 0.20 SER 280 -0.20 PRO 228

GLY 334 0.20 THR 281 -0.17 GLN 224

PRO 233 0.20 ILE 282 -0.18 ASN 275

GLY 334 0.17 ALA 283 -0.16 ASP 287

LEU 345 0.18 ARG 284 -0.18 LEU 223

LEU 345 0.18 LYS 285 -0.20 LYS 279

LEU 345 0.16 SER 286 -0.18 LYS 279

LEU 345 0.17 LEU 287 -0.21 VAL 340

LEU 345 0.18 PRO 288 -0.26 ILE 68

LEU 345 0.20 LYS 289 -0.23 VAL 340

LEU 345 0.19 VAL 290 -0.31 VAL 340

LEU 345 0.20 SER 291 -0.41 VAL 340

LEU 345 0.18 TYR 292 -0.43 VAL 340

LEU 345 0.17 VAL 293 -0.40 VAL 340

LEU 345 0.16 THR 294 -0.33 VAL 340

GLY 334 0.15 ALA 295 -0.33 VAL 340

GLY 334 0.16 MET 296 -0.28 ILE 333

GLY 334 0.17 ASP 297 -0.34 LEU 223

GLY 334 0.16 LEU 298 -0.38 ILE 333

GLY 334 0.17 PHE 299 -0.32 ILE 333

GLY 334 0.19 VAL 300 -0.27 ILE 333

GLY 334 0.18 SER 301 -0.35 ILE 333

GLY 334 0.17 VAL 302 -0.37 ILE 333

GLY 334 0.19 CYS 303 -0.29 ILE 333

GLY 334 0.21 PHE 304 -0.28 SER 329

GLY 334 0.20 ILE 305 -0.37 SER 329

GLY 334 0.20 PHE 306 -0.32 SER 329

GLY 334 0.22 VAL 307 -0.27 SER 329

GLY 334 0.23 PHE 308 -0.33 SER 329

GLY 334 0.21 SER 309 -0.37 SER 329

GLY 334 0.21 ALA 310 -0.29 SER 329

GLY 334 0.23 LEU 311 -0.28 PRO 325

GLY 334 0.22 VAL 312 -0.38 PRO 325

GLY 334 0.20 GLU 313 -0.36 ILE 322

GLY 334 0.21 TYR 314 -0.33 ILE 322

GLY 334 0.22 GLY 315 -0.38 ILE 322

GLY 334 0.20 THR 316 -0.47 ILE 322

GLY 334 0.19 LEU 317 -0.38 ILE 322

GLY 334 0.21 HIS 318 -0.35 ILE 322

GLY 334 0.20 TYR 319 -0.44 ILE 322

GLY 334 0.19 PHE 320 -0.42 ILE 322

GLY 334 0.18 VAL 321 -0.33 ILE 322

ASP 245 0.20 SER 322 -0.33 ILE 322

GLY 334 0.17 SER 323 -0.41 ILE 322

GLY 334 0.16 GLN 324 -0.39 ILE 322

GLY 334 0.17 PRO 325 -0.33 ILE 322

GLY 334 0.15 ALA 326 -0.34 ILE 322

GLY 334 0.15 ARG 327 -0.39 ILE 322

GLY 334 0.17 ALA 328 -0.37 ILE 322

GLY 334 0.17 ALA 329 -0.31 ILE 322

GLY 334 0.16 LYS 330 -0.31 ILE 322

GLY 334 0.17 MET 331 -0.34 ILE 322

GLY 334 0.17 ASP 332 -0.30 ILE 322

GLY 334 0.16 SER 333 -0.27 ILE 322

GLY 334 0.16 TYR 334 -0.30 VAL 326

GLY 334 0.17 ALA 335 -0.30 VAL 326

GLY 334 0.17 ARG 336 -0.26 SER 329

GLY 334 0.16 ILE 337 -0.27 SER 329

GLY 334 0.16 PHE 338 -0.31 SER 329

GLY 334 0.17 PHE 339 -0.31 SER 329

GLY 334 0.18 PRO 340 -0.27 SER 329

GLY 334 0.15 THR 341 -0.32 ILE 333

GLY 334 0.14 ALA 342 -0.38 SER 329

GLY 334 0.16 PHE 343 -0.33 ILE 333

VAL 249 0.17 CYS 344 -0.32 ILE 333

GLY 334 0.13 LEU 345 -0.39 ILE 333

GLY 334 0.13 PHE 346 -0.41 ILE 333

THR 245 0.16 ASN 347 -0.35 ILE 333

ILE 242 0.17 LEU 348 -0.36 ILE 333

GLY 234 0.15 VAL 349 -0.45 ILE 333

THR 237 0.15 TYR 350 -0.42 ILE 333

THR 237 0.27 TRP 351 -0.36 ILE 333

MET 233 0.26 VAL 352 -0.40 ILE 333

MET 233 0.22 SER 353 -0.46 ILE 333

MET 233 0.28 TYR 354 -0.41 VAL 340

MET 233 0.40 LEU 355 -0.37 VAL 340

ARG 232 0.34 TYR 356 -0.42 VAL 340

ARG 232 0.33 LEU 357 -0.45 VAL 340

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** 6x3x ***

CA distance fluctuations for 2403121503062936047

--- normal mode 26 ---

Should you encounter any unexpected behaviour,
please let us know.

* 6x3x *