Should you encounter any unexpected behaviour,
please let us know.

* 6x3u *

CA distance fluctuations for 2403121504002936075

--- normal mode 14 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLU 14 0.05 SER 7 -0.05 GLY 208

GLU 14 0.05 ASN 8 -0.04 GLY 208

GLU 14 0.05 MET 9 -0.05 LYS 88

GLU 14 0.06 SER 10 -0.06 LYS 88

GLU 14 0.06 LEU 11 -0.05 ASN 33

GLU 14 0.05 VAL 12 -0.05 GLY 37

GLU 14 0.06 LYS 13 -0.07 GLY 37

GLU 14 0.06 GLU 14 -0.08 GLY 37

GLU 14 0.06 THR 15 -0.06 GLY 37

GLU 14 0.06 VAL 16 -0.06 GLY 37

GLU 14 0.07 ASP 17 -0.09 GLY 37

ASP 24 0.06 ARG 18 -0.08 GLY 37

ASP 24 0.05 LEU 19 -0.06 GLY 37

ASP 24 0.06 LEU 20 -0.07 GLY 37

ASP 24 0.08 LYS 21 -0.08 GLY 37

ASP 20 0.09 GLY 22 -0.08 GLY 25

ASP 20 0.07 TYR 23 -0.07 GLY 25

ASP 20 0.07 ASP 24 -0.07 GLY 25

LEU 23 0.04 ILE 25 -0.06 LYS 105

ASP 24 0.05 ARG 26 -0.06 GLY 25

ARG 187 0.04 LEU 27 -0.05 GLY 25

ARG 187 0.05 ARG 28 -0.05 GLY 25

ASN 189 0.05 PRO 29 -0.05 GLY 25

THR 12 0.05 ASP 30 -0.05 GLY 25

ASN 189 0.04 PHE 31 -0.05 GLY 25

ARG 173 0.05 GLY 32 -0.05 GLY 25

ASN 11 0.05 GLY 33 -0.05 GLY 25

ASN 189 0.05 PRO 34 -0.04 GLY 25

ASN 189 0.06 PRO 35 -0.03 GLY 25

ASN 189 0.06 VAL 36 -0.03 GLY 25

PRO 52 0.06 ALA 37 -0.03 GLY 37

PRO 52 0.07 VAL 38 -0.03 THR 113

PRO 52 0.07 GLY 39 -0.03 THR 113

SER 54 0.08 MET 40 -0.03 THR 113

SER 54 0.09 ASN 41 -0.03 ASP 57

SER 54 0.10 ILE 42 -0.04 THR 216

LYS 106 0.10 ASP 43 -0.06 THR 215

SER 54 0.12 ILE 44 -0.06 VAL 213

LYS 117 0.16 ALA 45 -0.08 VAL 213

LYS 117 0.17 SER 46 -0.08 ASP 57

SER 54 0.16 ILE 47 -0.08 THR 61

SER 54 0.18 ASP 48 -0.14 GLN 152

SER 54 0.20 MET 49 -0.14 GLN 152

SER 54 0.19 VAL 50 -0.11 GLN 152

SER 54 0.21 SER 51 -0.14 PRO 52

GLU 270 0.20 GLU 52 -0.17 LYS 289

ASN 54 0.23 VAL 53 -0.18 LYS 289

ASN 54 0.22 ASN 54 -0.21 PRO 52

ASN 54 0.19 MET 55 -0.14 ARG 187

PRO 52 0.17 ASP 56 -0.12 GLY 51

SER 54 0.17 TYR 57 -0.10 GLN 152

SER 54 0.17 THR 58 -0.11 GLN 152

SER 54 0.15 LEU 59 -0.08 THR 61

LYS 106 0.15 THR 60 -0.08 THR 61

LYS 106 0.12 MET 61 -0.07 ARG 136

LYS 106 0.11 TYR 62 -0.06 ARG 136

VAL 108 0.10 PHE 63 -0.05 ARG 136

VAL 108 0.09 GLN 64 -0.05 THR 113

VAL 108 0.08 GLN 65 -0.04 THR 113

VAL 108 0.07 ALA 66 -0.03 THR 113

VAL 108 0.06 TRP 67 -0.03 GLY 37

PRO 52 0.05 ARG 68 -0.03 GLY 37

THR 12 0.05 ASP 69 -0.04 GLY 37

ASP 10 0.07 LYS 70 -0.04 GLY 37

THR 13 0.07 ARG 71 -0.05 GLY 37

ASP 20 0.05 LEU 72 -0.05 GLY 37

ASP 10 0.06 SER 73 -0.05 GLY 37

ASP 10 0.06 TYR 74 -0.05 GLY 37

ASP 10 0.06 ASN 75 -0.04 GLY 37

ASP 24 0.05 VAL 76 -0.05 GLY 37

GLU 14 0.04 ILE 77 -0.04 GLY 37

GLU 177 0.04 PRO 78 -0.03 ASP 57

GLU 14 0.04 LEU 79 -0.04 ASP 57

VAL 108 0.04 ASN 80 -0.04 ASP 57

VAL 108 0.05 LEU 81 -0.04 ASP 57

VAL 108 0.05 THR 82 -0.05 VAL 108

VAL 108 0.05 LEU 83 -0.05 VAL 108

VAL 108 0.05 ASP 84 -0.06 VAL 108

VAL 108 0.07 ASN 85 -0.07 VAL 108

VAL 108 0.06 ARG 86 -0.07 VAL 108

VAL 108 0.06 VAL 87 -0.06 ALA 88

VAL 108 0.06 ALA 88 -0.06 VAL 87

VAL 108 0.05 ASP 89 -0.06 ARG 86

ASP 17 0.05 GLN 90 -0.06 LYS 105

VAL 108 0.05 LEU 91 -0.05 LYS 105

ALA 109 0.05 TRP 92 -0.04 LYS 105

ALA 109 0.06 VAL 93 -0.03 LYS 105

ALA 109 0.07 PRO 94 -0.03 LYS 105

ALA 109 0.08 ASP 95 -0.03 LYS 112

ALA 109 0.09 THR 96 -0.03 CYS 151

ALA 109 0.10 TYR 97 -0.05 PHE 65

ALA 109 0.11 PHE 98 -0.05 GLN 152

LYS 103 0.12 LEU 99 -0.05 GLN 152

LYS 103 0.13 ASN 100 -0.08 THR 48

LYS 103 0.14 ASP 101 -0.09 ASP 63

LYS 103 0.17 LYS 102 -0.15 ASP 63

ALA 109 0.17 LYS 103 -0.15 THR 61

ALA 109 0.15 SER 104 -0.12 LYS 117

VAL 108 0.15 PHE 105 -0.14 LYS 117

VAL 108 0.14 VAL 106 -0.14 VAL 108

LYS 106 0.14 HIS 107 -0.14 VAL 108

VAL 108 0.12 GLY 108 -0.14 VAL 108

LYS 106 0.10 VAL 109 -0.13 LYS 106

LYS 106 0.07 THR 110 -0.12 LYS 106

VAL 108 0.07 VAL 111 -0.11 VAL 108

VAL 108 0.10 LYS 112 -0.12 VAL 108

VAL 108 0.09 ASN 113 -0.10 VAL 108

VAL 108 0.09 ARG 114 -0.08 VAL 108

VAL 108 0.08 MET 115 -0.06 VAL 108

VAL 108 0.06 ILE 116 -0.05 VAL 108

VAL 108 0.06 ARG 117 -0.04 VAL 108

VAL 108 0.05 LEU 118 -0.04 ASP 39

VAL 108 0.05 HIS 119 -0.03 GLY 37

ASP 10 0.05 PRO 120 -0.04 GLY 37

ASP 10 0.07 ASP 121 -0.04 GLY 37

ASP 10 0.06 GLY 122 -0.04 GLY 37

VAL 108 0.05 THR 123 -0.03 GLY 37

VAL 108 0.06 VAL 124 -0.03 ASP 39

VAL 108 0.06 LEU 125 -0.04 ASP 57

VAL 108 0.07 TYR 126 -0.05 THR 113

VAL 108 0.08 GLY 127 -0.05 VAL 108

VAL 108 0.10 LEU 128 -0.07 MET 112

LYS 106 0.11 ARG 129 -0.08 ARG 136

VAL 108 0.13 ILE 130 -0.09 ARG 136

LYS 106 0.15 THR 131 -0.11 ARG 136

VAL 108 0.14 THR 132 -0.10 THR 61

PRO 52 0.16 THR 133 -0.11 GLY 51

PRO 52 0.15 ALA 134 -0.10 SER 49

PRO 52 0.15 ALA 135 -0.12 SER 49

ASN 54 0.15 CYS 136 -0.09 SER 49

ASN 54 0.16 MET 137 -0.10 ASP 184

THR 271 0.16 MET 138 -0.07 LYS 289

THR 271 0.16 ASP 139 -0.06 LYS 289

GLU 270 0.18 LEU 140 -0.07 LYS 289

GLU 270 0.18 ARG 141 -0.06 LEU 357

GLU 270 0.19 ARG 142 -0.05 LEU 357

GLU 270 0.20 TYR 143 -0.06 LEU 357

GLU 270 0.20 PRO 144 -0.06 LEU 357

GLU 270 0.18 LEU 145 -0.05 LEU 357

GLU 270 0.17 ASP 146 -0.05 LEU 357

SER 54 0.15 GLU 147 -0.04 LEU 357

SER 54 0.15 GLN 148 -0.05 LEU 357

SER 54 0.14 ASN 149 -0.04 LEU 357

THR 151 0.15 CYS 150 -0.05 LEU 357

CYS 150 0.15 THR 151 -0.04 VAL 180

PRO 52 0.12 LEU 152 -0.04 THR 48

PRO 52 0.11 GLU 153 -0.04 LEU 357

PRO 52 0.10 ILE 154 -0.03 LEU 357

ARG 187 0.09 GLU 155 -0.03 LEU 357

ARG 187 0.08 SER 156 -0.03 LEU 357

ARG 187 0.07 TYR 157 -0.04 VAL 106

ARG 187 0.06 GLY 158 -0.04 VAL 106

ARG 187 0.06 TYR 159 -0.03 VAL 106

ASN 189 0.06 THR 160 -0.03 GLY 25

ASN 189 0.07 THR 161 -0.03 GLY 25

ASN 189 0.06 ASP 162 -0.03 GLY 25

ASN 189 0.06 ASP 163 -0.03 GLY 25

ASN 189 0.06 ILE 164 -0.03 GLY 25

ASN 189 0.07 GLU 165 -0.02 GLY 25

PRO 52 0.07 PHE 166 -0.02 THR 113

PRO 52 0.08 TYR 167 -0.02 GLY 37

SER 54 0.08 TRP 168 -0.02 PRO 78

SER 54 0.08 ARG 169 -0.02 PRO 78

SER 54 0.08 GLY 170 -0.03 PRO 78

SER 54 0.09 ASP 171 -0.02 PRO 78

SER 54 0.09 ASP 172 -0.02 PRO 78

SER 54 0.09 ASN 173 -0.03 ASP 57

SER 54 0.09 ALA 174 -0.03 ASP 57

SER 54 0.10 VAL 175 -0.03 ASP 57

SER 54 0.10 THR 176 -0.04 ASP 57

LYS 117 0.11 GLY 177 -0.06 LYS 214

SER 54 0.11 VAL 178 -0.05 HIS 56

SER 54 0.11 THR 179 -0.05 HIS 56

SER 54 0.11 LYS 180 -0.07 HIS 56

SER 54 0.12 ILE 181 -0.08 HIS 56

MET 70 0.14 GLU 182 -0.09 HIS 56

ASN 69 0.16 LEU 183 -0.10 THR 271

ILE 68 0.19 PRO 184 -0.13 THR 271

HIS 56 0.18 GLN 185 -0.13 THR 271

SER 54 0.16 PHE 186 -0.08 THR 271

SER 54 0.15 SER 187 -0.05 THR 271

SER 54 0.14 ILE 188 -0.04 GLY 51

SER 54 0.13 VAL 189 -0.03 VAL 180

SER 54 0.12 ASP 190 -0.03 VAL 180

SER 54 0.12 TYR 191 -0.03 THR 133

SER 54 0.11 LYS 192 -0.02 THR 133

SER 54 0.10 LEU 193 -0.02 THR 133

SER 54 0.10 ILE 194 -0.02 LEU 357

ASN 189 0.09 THR 195 -0.02 LEU 357

ASN 189 0.09 LYS 196 -0.02 LEU 357

ASP 184 0.08 LYS 197 -0.02 LEU 357

GLU 183 0.10 VAL 198 -0.03 LEU 357

ALA 182 0.10 VAL 199 -0.03 SER 286

ALA 182 0.10 PHE 200 -0.04 SER 286

VAL 180 0.10 SER 201 -0.05 SER 286

VAL 180 0.07 THR 202 -0.05 SER 286

ALA 182 0.06 GLY 203 -0.04 SER 286

GLU 183 0.07 SER 204 -0.03 SER 286

ASN 189 0.07 TYR 205 -0.03 LEU 357

ASN 189 0.08 PRO 206 -0.02 LEU 357

ASN 189 0.09 ARG 207 -0.03 LEU 357

PRO 52 0.09 LEU 208 -0.03 LEU 357

PRO 52 0.10 SER 209 -0.03 LEU 357

SER 54 0.11 LEU 210 -0.03 THR 151

SER 54 0.12 SER 211 -0.03 VAL 180

SER 54 0.13 PHE 212 -0.04 VAL 180

SER 54 0.14 LYS 213 -0.04 CYS 150

SER 54 0.15 LEU 214 -0.05 SER 187

SER 54 0.15 LYS 215 -0.05 LEU 357

SER 54 0.16 ARG 216 -0.08 LEU 272

ASN 275 0.16 ASN 217 -0.11 THR 271

SER 272 0.17 ILE 218 -0.11 THR 271

ASN 275 0.17 GLY 219 -0.14 THR 271

ASN 275 0.20 TYR 220 -0.19 THR 271

SER 272 0.21 PHE 221 -0.16 LEU 268

THR 277 0.20 ILE 222 -0.14 LEU 268

THR 277 0.22 LEU 223 -0.18 LEU 268

THR 281 0.27 GLN 224 -0.27 LEU 268

SER 272 0.24 THR 225 -0.20 LEU 268

LEU 274 0.23 TYR 226 -0.09 SER 353

LEU 274 0.28 MET 227 -0.11 LEU 268

LEU 274 0.37 PRO 228 -0.14 ILE 264

LEU 274 0.30 SER 229 -0.11 PHE 289

LEU 274 0.28 ILE 230 -0.09 VAL 349

ILE 270 0.37 LEU 231 -0.10 VAL 349

ILE 270 0.33 ILE 232 -0.13 SER 301

ILE 270 0.26 THR 233 -0.08 VAL 349

ILE 270 0.33 ILE 234 -0.10 PRO 315

ILE 270 0.42 LEU 235 -0.12 ILE 305

SER 267 0.30 SER 236 -0.11 PRO 315

THR 266 0.29 TRP 237 -0.10 PRO 315

THR 266 0.40 VAL 238 -0.13 PRO 315

PRO 263 0.37 SER 239 -0.14 PRO 315

PRO 263 0.30 PHE 240 -0.12 PRO 315

VAL 262 0.34 TRP 241 -0.14 PRO 315

PRO 263 0.37 ILE 242 -0.23 TYR 319

ALA 248 0.30 ASN 243 -0.20 TYR 319

ALA 246 0.32 TYR 244 -0.19 PRO 315

ALA 246 0.37 ASP 245 -0.29 SER 322

ALA 248 0.42 ALA 246 -0.37 TYR 319

ALA 248 0.44 SER 247 -0.30 ASN 248

ALA 248 0.59 ALA 248 -0.36 SER 251

ALA 248 0.50 ALA 249 -0.41 GLY 315

ALA 248 0.39 ARG 250 -0.31 GLY 315

ALA 249 0.40 VAL 251 -0.27 GLY 315

ALA 252 0.52 ALA 252 -0.33 GLY 315

ALA 252 0.41 LEU 253 -0.33 VAL 312

ALA 252 0.34 GLY 254 -0.22 VAL 312

ALA 252 0.37 ILE 255 -0.24 LEU 311

THR 256 0.41 THR 256 -0.30 PHE 308

THR 256 0.31 THR 257 -0.25 PHE 308

THR 256 0.29 VAL 258 -0.20 PHE 308

THR 260 0.36 LEU 259 -0.25 LEU 274

THR 263 0.35 THR 260 -0.27 PHE 304

THR 263 0.30 MET 261 -0.20 SER 301

THR 263 0.32 THR 262 -0.21 PRO 233

THR 263 0.41 THR 263 -0.32 THR 277

THR 263 0.35 ILE 264 -0.26 SER 301

HIS 267 0.31 ASN 265 -0.20 SER 301

HIS 267 0.36 THR 266 -0.27 THR 281

HIS 267 0.42 HIS 267 -0.40 THR 281

HIS 267 0.34 LEU 268 -0.28 ARG 284

HIS 267 0.29 ARG 269 -0.23 ARG 284

THR 271 0.33 GLU 270 -0.33 LYS 285

THR 271 0.32 THR 271 -0.34 LYS 289

THR 271 0.27 LEU 272 -0.28 LYS 289

THR 271 0.24 PRO 273 -0.23 LYS 289

THR 271 0.21 LYS 274 -0.19 LYS 285

THR 271 0.18 ILE 275 -0.15 LYS 289

THR 271 0.16 PRO 276 -0.12 SER 286

THR 271 0.17 TYR 277 -0.08 SER 286

THR 271 0.18 VAL 278 -0.07 LYS 289

GLU 270 0.20 LYS 279 -0.07 SER 291

GLU 270 0.19 ALA 280 -0.06 LEU 357

HIS 267 0.22 ILE 281 -0.08 VAL 293

HIS 267 0.22 ASP 282 -0.09 VAL 293

HIS 267 0.20 MET 283 -0.06 SER 353

HIS 267 0.21 TYR 284 -0.06 SER 353

THR 263 0.24 LEU 285 -0.11 THR 225

HIS 267 0.21 MET 286 -0.09 SER 301

THR 263 0.20 GLY 287 -0.06 SER 353

THR 263 0.23 CYS 288 -0.10 SER 229

THR 263 0.23 PHE 289 -0.12 SER 301

THR 263 0.19 VAL 290 -0.08 SER 301

ALA 252 0.21 PHE 291 -0.07 SER 229

ALA 252 0.24 VAL 292 -0.11 SER 301

ALA 252 0.21 PHE 293 -0.11 SER 301

ALA 252 0.20 MET 294 -0.08 SER 301

ALA 252 0.24 ALA 295 -0.08 SER 301

ALA 252 0.26 LEU 296 -0.13 PHE 308

ALA 252 0.20 LEU 297 -0.10 PHE 308

ALA 248 0.21 GLU 298 -0.08 ALA 319

ALA 249 0.26 TYR 299 -0.12 VAL 312

ALA 254 0.24 ALA 300 -0.14 TRP 246

ALA 246 0.20 LEU 301 -0.11 ARG 323

ALA 246 0.24 VAL 302 -0.12 ALA 319

ALA 246 0.27 ASN 303 -0.16 TYR 319

ALA 246 0.19 TYR 304 -0.16 ALA 319

ALA 246 0.20 ILE 305 -0.15 ALA 319

ALA 246 0.26 PHE 306 -0.16 ALA 316

ASP 245 0.24 PHE 307 -0.19 ALA 316

ASP 245 0.19 SER 308 -0.18 ALA 316

ASP 245 0.21 GLN 309 -0.15 ALA 316

ALA 246 0.25 PRO 310 -0.14 ALA 316

ALA 246 0.23 ALA 311 -0.12 ALA 316

ALA 246 0.21 ARG 312 -0.11 ALA 316

ALA 246 0.24 ALA 313 -0.12 ALA 316

ALA 246 0.24 ALA 314 -0.12 PRO 315

ALA 246 0.21 ALA 315 -0.09 ALA 316

ALA 246 0.21 ILE 316 -0.08 ALA 316

ALA 248 0.24 ASP 317 -0.10 PRO 315

ALA 248 0.22 ARG 318 -0.09 PRO 315

ALA 248 0.20 TRP 319 -0.07 PRO 315

ALA 248 0.22 SER 320 -0.07 PRO 315

PRO 263 0.24 ARG 321 -0.09 PRO 315

TYR 319 0.24 ILE 322 -0.07 PRO 315

ALA 248 0.19 PHE 323 -0.06 PRO 315

ALA 248 0.21 PHE 324 -0.06 PRO 315

THR 266 0.24 PRO 325 -0.06 PRO 315

THR 266 0.20 VAL 326 -0.05 PRO 315

ALA 252 0.17 VAL 327 -0.04 PRO 315

ALA 252 0.19 PHE 328 -0.05 PRO 315

ILE 270 0.20 SER 329 -0.05 PRO 315

THR 266 0.16 PHE 330 -0.04 PRO 315

THR 263 0.17 PHE 331 -0.04 ALA 176

ILE 270 0.18 ASN 332 -0.04 PRO 315

ILE 270 0.17 ILE 333 -0.03 ALA 176

THR 263 0.15 VAL 334 -0.04 ALA 176

THR 263 0.17 TYR 335 -0.04 ALA 176

THR 268 0.17 TRP 336 -0.03 ALA 176

GLU 270 0.15 LEU 337 -0.03 ALA 176

GLU 270 0.15 TYR 338 -0.04 ALA 176

GLU 270 0.16 TYR 339 -0.04 ALA 176

GLU 270 0.16 VAL 340 -0.03 ALA 176

LYS 70 0.07 ASP 10 -0.08 GLY 25

LYS 70 0.06 ASN 11 -0.07 GLY 25

LYS 70 0.07 THR 12 -0.07 GLY 25

ARG 71 0.07 THR 13 -0.08 GLY 25

ARG 71 0.05 VAL 14 -0.08 GLY 25

ARG 71 0.05 PHE 15 -0.07 GLY 25

ARG 71 0.06 THR 16 -0.08 GLY 25

GLY 22 0.06 ARG 17 -0.08 ASP 24

GLY 22 0.05 ILE 18 -0.07 ASP 24

GLY 22 0.06 LEU 19 -0.07 ASP 24

GLY 22 0.09 ASP 20 -0.08 ASP 24

GLY 22 0.07 ARG 21 -0.07 ASP 24

GLY 22 0.06 LEU 22 -0.06 ASP 24

GLY 22 0.08 LEU 23 -0.07 ASP 24

GLY 22 0.08 ASP 24 -0.07 ASP 20

GLY 22 0.07 GLY 25 -0.07 LYS 21

GLY 22 0.07 TYR 26 -0.06 ARG 17

GLY 22 0.06 ASP 27 -0.05 LEU 20

LYS 21 0.05 ASN 28 -0.04 ASP 24

LYS 21 0.04 ARG 29 -0.05 ASP 27

GLY 22 0.04 LEU 30 -0.04 LYS 118

GLY 22 0.04 ARG 31 -0.05 LYS 118

GLY 22 0.05 PRO 32 -0.05 LYS 71

GLY 22 0.04 GLY 33 -0.05 SER 286

GLY 22 0.04 LEU 34 -0.05 SER 286

GLY 22 0.04 GLY 35 -0.07 ARG 37

GLY 22 0.04 GLU 36 -0.12 ARG 37

GLY 22 0.04 ARG 37 -0.12 GLU 36

GLY 22 0.04 VAL 38 -0.06 SER 286

GLY 22 0.04 THR 39 -0.06 SER 286

THR 126 0.04 GLU 40 -0.07 SER 286

THR 126 0.05 VAL 41 -0.07 SER 286

THR 126 0.06 LYS 42 -0.07 SER 286

THR 126 0.05 THR 43 -0.08 SER 286

PHE 105 0.05 ASP 44 -0.09 ASN 69

PHE 105 0.06 ILE 45 -0.10 ASN 69

LYS 103 0.07 PHE 46 -0.09 ASN 69

LYS 103 0.08 VAL 47 -0.10 ASN 69

LYS 103 0.09 THR 48 -0.10 LYS 102

ASN 54 0.10 SER 49 -0.12 ALA 135

ASN 54 0.10 PHE 50 -0.13 ASN 69

ASN 54 0.13 GLY 51 -0.16 ASN 69

ASN 54 0.14 PRO 52 -0.21 ASN 54

ASN 54 0.13 VAL 53 -0.18 SER 286

ASN 54 0.16 SER 54 -0.21 ILE 68

MET 49 0.12 ASP 55 -0.24 SER 286

MET 49 0.17 HIS 56 -0.26 SER 286

MET 49 0.21 ASP 57 -0.23 ILE 68

ASP 48 0.12 MET 58 -0.21 SER 286

ASP 48 0.12 GLU 59 -0.20 ILE 68

THR 133 0.10 TYR 60 -0.19 ASN 69

THR 133 0.12 THR 61 -0.18 ASN 69

THR 133 0.10 ILE 62 -0.15 ASN 69

LYS 103 0.10 ASP 63 -0.15 LYS 102

PHE 105 0.09 VAL 64 -0.11 ASN 69

PHE 105 0.08 PHE 65 -0.09 ASN 69

THR 110 0.07 PHE 66 -0.09 ASN 69

PHE 105 0.06 ARG 67 -0.07 ASN 69

THR 110 0.05 GLN 68 -0.07 ASN 69

THR 126 0.05 SER 69 -0.06 ASN 69

THR 126 0.06 TRP 70 -0.06 SER 286

GLY 125 0.05 LYS 71 -0.05 SER 286

GLY 22 0.04 ASP 72 -0.05 LYS 118

GLY 22 0.05 GLU 73 -0.06 SER 10

GLY 22 0.06 ARG 74 -0.06 SER 10

GLY 22 0.05 LEU 75 -0.05 ASP 24

GLY 22 0.05 LYS 76 -0.05 SER 10

GLY 22 0.05 PHE 77 -0.06 ASP 24

ARG 173 0.04 LYS 78 -0.06 ASP 24

ARG 173 0.05 GLY 79 -0.06 ASP 24

ARG 173 0.05 PRO 80 -0.06 ASP 24

ARG 173 0.06 MET 81 -0.05 GLY 25

ARG 173 0.06 THR 82 -0.05 GLY 25

ARG 173 0.06 VAL 83 -0.05 GLY 25

LEU 128 0.05 LEU 84 -0.05 GLY 25

LEU 128 0.05 ARG 85 -0.04 GLY 25

ARG 187 0.04 LEU 86 -0.05 GLY 25

ARG 187 0.05 ASN 87 -0.05 LYS 105

ARG 187 0.05 ASN 88 -0.06 LYS 112

ARG 187 0.04 LEU 89 -0.05 GLY 104

ASP 24 0.04 MET 90 -0.05 GLY 25

ARG 187 0.04 ALA 91 -0.06 LYS 118

PRO 115 0.04 SER 92 -0.05 LYS 118

LEU 89 0.04 LYS 93 -0.05 GLY 25

GLY 22 0.04 ILE 94 -0.05 LYS 118

GLY 22 0.03 TRP 95 -0.06 LYS 118

ASP 184 0.03 THR 96 -0.07 LYS 118

PHE 105 0.03 PRO 97 -0.08 LYS 118

PHE 105 0.04 ASP 98 -0.09 LYS 118

PHE 105 0.04 THR 99 -0.10 LYS 118

PHE 105 0.05 PHE 100 -0.11 LYS 118

PHE 105 0.05 PHE 101 -0.12 LYS 118

ASP 184 0.03 HIS 102 -0.12 ASN 69

ASP 184 0.04 ASN 103 -0.14 ASN 69

THR 133 0.07 GLY 104 -0.14 LYS 118

THR 133 0.10 LYS 105 -0.17 LYS 118

THR 133 0.12 LYS 106 -0.18 LYS 118

PHE 105 0.12 SER 107 -0.17 LYS 118

PHE 105 0.13 VAL 108 -0.17 LYS 118

PHE 105 0.13 ALA 109 -0.12 LYS 118

LYS 103 0.11 HIS 110 -0.11 LYS 117

ALA 109 0.11 ASN 111 -0.12 VAL 106

ALA 109 0.12 MET 112 -0.11 VAL 106

ALA 109 0.11 THR 113 -0.07 LEU 128

ALA 109 0.10 MET 114 -0.07 VAL 106

ALA 109 0.09 PRO 115 -0.08 VAL 106

ALA 109 0.08 ASN 116 -0.07 LYS 117

PHE 105 0.07 LYS 117 -0.06 LYS 117

ARG 187 0.05 LEU 118 -0.06 LYS 117

ARG 187 0.05 LEU 119 -0.05 LYS 117

LEU 128 0.06 ARG 120 -0.04 LYS 117

THR 172 0.04 ILE 121 -0.04 GLY 25

ARG 173 0.05 THR 122 -0.04 GLY 25

ARG 173 0.05 GLU 123 -0.05 ASP 24

THR 172 0.05 ASP 124 -0.06 SER 7

LYS 71 0.05 GLY 125 -0.05 SER 10

LYS 42 0.06 THR 126 -0.05 SER 286

ASP 24 0.04 LEU 127 -0.05 LYS 117

ARG 120 0.06 LEU 128 -0.05 LYS 117

PHE 105 0.05 TYR 129 -0.06 LYS 117

PHE 105 0.06 THR 130 -0.07 LYS 117

PHE 105 0.08 MET 131 -0.08 LYS 117

PHE 105 0.09 ARG 132 -0.09 LYS 117

PHE 105 0.11 LEU 133 -0.12 LYS 117

PHE 105 0.11 THR 134 -0.14 LYS 103

SER 107 0.11 VAL 135 -0.14 ASN 69

THR 133 0.11 ARG 136 -0.18 ASN 69

THR 133 0.08 ALA 137 -0.17 ASN 69

THR 58 0.07 GLU 138 -0.17 ILE 68

ASP 48 0.05 CYS 139 -0.17 SER 286

ARG 317 0.04 PRO 140 -0.18 SER 286

ARG 317 0.05 MET 141 -0.19 SER 286

ARG 317 0.05 HIS 142 -0.19 SER 286

ARG 317 0.05 LEU 143 -0.20 SER 286

ARG 317 0.06 GLU 144 -0.19 SER 286

ARG 317 0.05 ASP 145 -0.18 LYS 285

VAL 53 0.06 PHE 146 -0.20 LYS 285

VAL 53 0.07 PRO 147 -0.20 LYS 285

VAL 53 0.06 MET 148 -0.18 LYS 285

VAL 53 0.05 ASP 149 -0.18 SER 286

VAL 199 0.05 ALA 150 -0.16 SER 286

SER 201 0.05 HIS 151 -0.17 SER 286

SER 201 0.05 ALA 152 -0.15 SER 286

THR 133 0.05 CYS 153 -0.16 SER 286

THR 133 0.04 PRO 154 -0.15 SER 286

THR 133 0.04 LEU 155 -0.13 ASN 69

THR 133 0.03 LYS 156 -0.12 SER 286

PHE 105 0.04 PHE 157 -0.11 ASN 69

PHE 105 0.03 GLY 158 -0.10 ASN 69

PHE 105 0.03 SER 159 -0.09 LYS 118

ARG 317 0.03 TYR 160 -0.09 LYS 118

ARG 317 0.03 ALA 161 -0.08 LYS 118

ARG 317 0.02 TYR 162 -0.07 PRO 64

GLN 314 0.02 THR 163 -0.08 PRO 64

GLN 314 0.02 ARG 164 -0.08 SER 286

GLY 22 0.03 ALA 165 -0.07 SER 286

GLY 22 0.03 GLU 166 -0.07 SER 286

GLY 22 0.03 VAL 167 -0.07 SER 286

THR 126 0.03 VAL 168 -0.08 SER 286

THR 126 0.04 TYR 169 -0.08 SER 286

THR 126 0.05 GLU 170 -0.09 SER 286

THR 126 0.05 TRP 171 -0.09 SER 286

THR 82 0.06 THR 172 -0.08 SER 286

THR 82 0.06 ARG 173 -0.08 SER 286

THR 82 0.06 GLU 174 -0.08 SER 286

THR 82 0.05 PRO 175 -0.09 SER 286

THR 82 0.05 ALA 176 -0.10 SER 286

SER 201 0.06 ARG 177 -0.09 SER 286

SER 201 0.05 SER 178 -0.09 SER 286

SER 201 0.07 VAL 179 -0.10 SER 286

SER 201 0.10 VAL 180 -0.18 VAL 181

PHE 200 0.08 VAL 181 -0.18 VAL 180

PHE 200 0.10 ALA 182 -0.10 VAL 180

VAL 198 0.10 GLU 183 -0.08 SER 286

ASN 54 0.10 ASP 184 -0.10 MET 137

ASN 54 0.10 GLY 185 -0.09 ALA 135

ASN 54 0.11 SER 186 -0.11 ASN 54

ASN 54 0.13 ARG 187 -0.15 ASN 54

ASN 54 0.14 LEU 188 -0.15 ASN 54

VAL 53 0.15 ASN 189 -0.16 VAL 53

VAL 53 0.13 GLN 190 -0.18 SER 286

ASN 54 0.10 TYR 191 -0.16 SER 286

ASN 54 0.09 ASP 192 -0.14 SER 286

ASN 54 0.08 LEU 193 -0.13 SER 286

VAL 199 0.08 LEU 194 -0.12 SER 286

SER 201 0.08 GLY 195 -0.12 SER 286

SER 201 0.07 GLN 196 -0.12 SER 286

HIS 216 0.05 THR 197 -0.11 SER 286

HIS 216 0.07 VAL 198 -0.11 SER 286

THR 82 0.03 ASP 199 -0.12 SER 286

THR 82 0.03 SER 200 -0.11 SER 286

THR 82 0.03 GLY 201 -0.10 SER 286

GLN 314 0.03 ILE 202 -0.10 SER 286

GLN 314 0.03 VAL 203 -0.10 SER 286

GLN 314 0.03 GLN 204 -0.09 SER 286

GLN 314 0.03 SER 205 -0.10 THR 176

GLN 314 0.03 SER 206 -0.11 THR 176

GLN 314 0.03 THR 207 -0.08 ALA 174

GLN 314 0.03 GLY 208 -0.09 ASN 173

GLN 314 0.03 GLU 209 -0.09 SER 286

ARG 317 0.03 TYR 210 -0.09 SER 286

ARG 317 0.03 VAL 211 -0.09 SER 286

ARG 317 0.03 VAL 212 -0.10 SER 286

THR 82 0.03 MET 213 -0.10 SER 286

ARG 317 0.03 THR 214 -0.12 SER 286

VAL 198 0.04 THR 215 -0.13 SER 286

VAL 198 0.07 HIS 216 -0.14 SER 286

ASN 54 0.06 PHE 217 -0.14 SER 286

ASN 54 0.06 HIS 218 -0.14 SER 286

ASN 54 0.07 LEU 219 -0.15 SER 286

VAL 53 0.08 LYS 220 -0.15 SER 286

VAL 53 0.09 ARG 221 -0.17 SER 286

VAL 53 0.10 LYS 222 -0.15 SER 286

VAL 53 0.10 ILE 223 -0.16 LYS 285

THR 271 0.12 GLY 224 -0.15 LYS 285

THR 271 0.14 TYR 225 -0.18 LYS 285

THR 271 0.12 PHE 226 -0.20 LYS 285

TYR 277 0.11 VAL 227 -0.17 LYS 285

TYR 277 0.14 ILE 228 -0.17 THR 281

THR 271 0.16 GLN 229 -0.22 THR 281

THR 271 0.12 THR 230 -0.23 THR 281

THR 271 0.09 TYR 231 -0.20 THR 281

LEU 268 0.10 LEU 232 -0.18 THR 281

LEU 268 0.13 PRO 233 -0.21 THR 281

LEU 268 0.09 CYS 234 -0.23 THR 278

LEU 268 0.08 ILE 235 -0.18 THR 278

LEU 268 0.10 MET 236 -0.18 LEU 274

LEU 268 0.10 THR 237 -0.25 LEU 274

LEU 268 0.07 VAL 238 -0.22 LEU 274

LEU 268 0.07 ILE 239 -0.18 LEU 274

LEU 268 0.09 LEU 240 -0.21 ILE 270

VAL 297 0.08 SER 241 -0.25 ILE 270

LEU 268 0.06 GLN 242 -0.21 ILE 270

LEU 268 0.07 VAL 243 -0.20 ILE 270

VAL 238 0.09 SER 244 -0.26 PRO 263

LEU 268 0.05 PHE 245 -0.24 PRO 263

ALA 311 0.07 TRP 246 -0.22 SER 247

ILE 242 0.13 LEU 247 -0.29 SER 247

ASN 243 0.15 ASN 248 -0.30 SER 247

TRP 241 0.19 ARG 249 -0.34 VAL 262

ASN 243 0.29 GLU 250 -0.38 VAL 262

ILE 242 0.35 SER 251 -0.46 VAL 262

ILE 242 0.47 VAL 252 -0.51 PRO 263

ILE 242 0.41 PRO 253 -0.62 PRO 263

ILE 242 0.26 ALA 254 -0.54 PRO 263

VAL 238 0.20 ARG 255 -0.42 PRO 263

VAL 238 0.30 THR 256 -0.45 PRO 263

SER 239 0.26 VAL 257 -0.47 PRO 263

ALA 300 0.18 PHE 258 -0.36 PRO 263

LEU 235 0.17 GLY 259 -0.32 SER 267

LEU 235 0.29 VAL 260 -0.36 SER 267

LEU 235 0.19 THR 261 -0.39 THR 271

PHE 293 0.15 THR 262 -0.32 THR 271

LEU 231 0.14 VAL 263 -0.31 THR 271

ILE 232 0.19 LEU 264 -0.36 LEU 274

PHE 293 0.15 THR 265 -0.37 LEU 274

PHE 293 0.10 MET 266 -0.30 LEU 274

PRO 228 0.18 THR 267 -0.31 THR 275

LEU 268 0.18 THR 268 -0.38 THR 278

LEU 268 0.14 LEU 269 -0.33 THR 278

LEU 268 0.10 SER 270 -0.29 THR 278

LEU 268 0.14 ILE 271 -0.33 ILE 282

LEU 268 0.19 SER 272 -0.37 ILE 282

TYR 277 0.12 ALA 273 -0.31 ILE 282

VAL 53 0.09 ARG 274 -0.30 ILE 282

THR 271 0.15 ASN 275 -0.33 ILE 282

VAL 53 0.13 SER 276 -0.31 LYS 285

VAL 53 0.10 LEU 277 -0.27 LYS 285

GLU 52 0.10 PRO 278 -0.27 SER 286

GLN 185 0.12 LYS 279 -0.25 SER 286

PRO 184 0.08 VAL 280 -0.22 SER 286

ARG 317 0.07 ALA 281 -0.21 SER 286

ARG 317 0.07 TYR 282 -0.20 SER 286

ARG 317 0.07 ALA 283 -0.21 ILE 282

ARG 317 0.06 THR 284 -0.21 ILE 282

ILE 321 0.06 ALA 285 -0.20 ILE 282

PHE 289 0.07 MET 286 -0.23 ILE 282

ALA 291 0.10 ASP 287 -0.23 ILE 282

ILE 321 0.07 TRP 288 -0.21 ILE 282

ASP 287 0.07 PHE 289 -0.20 THR 278

TYR 277 0.07 ILE 290 -0.23 THR 278

ASP 287 0.10 ALA 291 -0.21 THR 278

ILE 321 0.07 VAL 292 -0.19 LEU 274

TYR 277 0.06 CYS 293 -0.21 LEU 274

SER 299 0.09 TYR 294 -0.23 LEU 274

SER 299 0.13 ALA 295 -0.21 THR 271

ILE 321 0.08 PHE 296 -0.21 THR 271

SER 241 0.08 VAL 297 -0.24 THR 271

LEU 223 0.10 PHE 298 -0.22 SER 267

ALA 295 0.13 SER 299 -0.22 PRO 263

LEU 223 0.07 ALA 300 -0.25 PRO 263

LEU 231 0.08 LEU 301 -0.29 PRO 263

LEU 223 0.09 ILE 302 -0.27 PRO 263

LEU 223 0.08 GLU 303 -0.27 PRO 263

LEU 231 0.07 PHE 304 -0.32 PRO 263

SER 329 0.09 ALA 305 -0.35 ILE 242

TYR 309 0.14 THR 306 -0.34 ILE 242

THR 306 0.08 VAL 307 -0.31 PRO 263

ILE 322 0.11 ASN 308 -0.37 PRO 263

PRO 325 0.14 TYR 309 -0.44 ASN 243

THR 306 0.13 PHE 310 -0.32 ALA 261

ILE 322 0.12 THR 311 -0.37 ALA 261

ILE 322 0.16 LYS 312 -0.41 ASP 260

ILE 322 0.14 SER 313 -0.36 ASP 260

SER 329 0.10 GLN 314 -0.33 ASP 260

ALA 316 0.13 PRO 315 -0.33 ASP 260

PRO 315 0.13 ALA 316 -0.28 ASP 260

GLY 219 0.08 ARG 317 -0.26 ASP 260

LEU 223 0.07 ALA 318 -0.29 VAL 262

LEU 223 0.05 ALA 319 -0.26 VAL 262

SER 325 0.06 LYS 320 -0.23 VAL 262

SER 325 0.10 ILE 321 -0.24 PRO 263

SER 325 0.08 ASP 322 -0.25 PRO 263

SER 325 0.06 ARG 323 -0.21 PRO 263

ALA 328 0.13 LEU 324 -0.20 PRO 263

LEU 324 0.11 SER 325 -0.21 PRO 263

VAL 53 0.04 ARG 326 -0.19 PRO 263

LEU 324 0.07 ILE 327 -0.16 PRO 263

LEU 324 0.13 ALA 328 -0.18 PRO 263

LEU 324 0.08 PHE 329 -0.18 PRO 263

LEU 324 0.05 PRO 330 -0.15 PRO 263

LEU 324 0.06 LEU 331 -0.14 PRO 263

PHE 336 0.07 LEU 332 -0.16 PRO 263

LYS 196 0.05 PHE 333 -0.16 LEU 274

LYS 196 0.06 GLY 334 -0.14 LEU 274

LEU 324 0.06 ILE 335 -0.14 LEU 274

LEU 332 0.07 PHE 336 -0.16 THR 278

LYS 196 0.06 ASN 337 -0.15 THR 278

LYS 196 0.06 LEU 338 -0.14 THR 278

VAL 199 0.06 VAL 339 -0.14 THR 278

VAL 199 0.06 TYR 340 -0.16 THR 278

VAL 199 0.06 TRP 341 -0.14 ILE 282

VAL 199 0.06 ALA 342 -0.13 ILE 282

VAL 199 0.06 THR 343 -0.15 ILE 282

VAL 199 0.06 TYR 344 -0.16 ILE 282

VAL 199 0.07 LEU 345 -0.14 LYS 285

VAL 199 0.07 ASN 346 -0.13 SER 286

VAL 199 0.06 ARG 347 -0.15 SER 286

LYS 21 0.06 SER 7 -0.06 ASP 124

LYS 21 0.06 ASN 8 -0.07 ARG 37

LYS 21 0.06 MET 9 -0.06 ARG 37

LYS 21 0.07 SER 10 -0.06 GLU 73

LYS 21 0.06 LEU 11 -0.05 ARG 37

LYS 21 0.06 VAL 12 -0.05 ARG 37

LYS 21 0.06 LYS 13 -0.06 ARG 74

ASP 17 0.07 GLU 14 -0.05 ARG 74

ASP 17 0.06 THR 15 -0.04 ARG 74

ASP 17 0.05 VAL 16 -0.05 ARG 74

ASP 17 0.06 ASP 17 -0.07 GLY 25

GLY 37 0.06 ARG 18 -0.05 GLY 25

GLY 37 0.05 LEU 19 -0.05 GLY 25

GLY 37 0.05 LEU 20 -0.06 GLY 25

GLY 37 0.07 LYS 21 -0.07 GLY 25

GLU 36 0.07 GLY 22 -0.07 THR 13

THR 133 0.05 TYR 23 -0.06 GLY 25

THR 133 0.06 ASP 24 -0.05 GLY 25

THR 133 0.06 ILE 25 -0.05 ASP 24

THR 133 0.07 ARG 26 -0.04 ASP 24

THR 133 0.06 LEU 27 -0.04 ASP 24

THR 271 0.07 ARG 28 -0.04 GLY 25

THR 271 0.06 PRO 29 -0.04 GLY 25

THR 271 0.06 ASP 30 -0.04 GLY 25

THR 271 0.07 PHE 31 -0.04 GLY 25

PRO 34 0.07 GLY 32 -0.04 ASP 24

PRO 34 0.13 GLY 33 -0.04 GLY 25

GLY 33 0.13 PRO 34 -0.03 LYS 70

THR 271 0.07 PRO 35 -0.04 LYS 70

THR 271 0.07 VAL 36 -0.05 LYS 70

THR 271 0.06 ALA 37 -0.05 THR 123

THR 271 0.07 VAL 38 -0.06 TRP 67

THR 271 0.06 GLY 39 -0.06 VAL 108

THR 271 0.07 MET 40 -0.08 VAL 108

THR 271 0.06 ASN 41 -0.09 VAL 108

THR 271 0.06 ILE 42 -0.10 VAL 108

ASP 57 0.05 ASP 43 -0.11 VAL 108

ASP 57 0.06 ILE 44 -0.12 VAL 108

ASP 57 0.06 ALA 45 -0.13 PRO 64

ASP 57 0.09 SER 46 -0.15 PRO 64

ASP 57 0.12 ILE 47 -0.15 PRO 64

ASP 57 0.18 ASP 48 -0.18 PRO 64

ASP 57 0.21 MET 49 -0.19 PRO 64

ASP 57 0.14 VAL 50 -0.19 HIS 56

THR 271 0.17 SER 51 -0.23 HIS 56

THR 271 0.21 GLU 52 -0.22 HIS 56

THR 271 0.25 VAL 53 -0.28 HIS 56

THR 271 0.23 ASN 54 -0.25 ASP 57

THR 271 0.20 MET 55 -0.19 PRO 52

THR 271 0.17 ASP 56 -0.17 ASP 57

ASP 57 0.15 TYR 57 -0.16 ASP 57

ASP 57 0.14 THR 58 -0.17 LYS 106

ASP 57 0.11 LEU 59 -0.15 VAL 108

SER 54 0.08 THR 60 -0.15 VAL 108

THR 271 0.06 MET 61 -0.13 VAL 108

THR 271 0.05 TYR 62 -0.11 VAL 108

THR 271 0.06 PHE 63 -0.11 VAL 108

THR 271 0.06 GLN 64 -0.08 VAL 108

THR 271 0.06 GLN 65 -0.07 VAL 108

THR 271 0.05 ALA 66 -0.06 VAL 108

THR 271 0.05 TRP 67 -0.06 VAL 38

THR 271 0.05 ARG 68 -0.05 GLY 122

THR 271 0.05 ASP 69 -0.04 ALA 37

ASP 10 0.07 LYS 70 -0.05 VAL 36

THR 271 0.05 ARG 71 -0.04 GLY 25

THR 271 0.04 LEU 72 -0.04 GLY 25

ASP 10 0.04 SER 73 -0.04 VAL 340

GLY 37 0.05 TYR 74 -0.04 ARG 37

GLY 37 0.05 ASN 75 -0.05 ARG 37

GLY 37 0.05 VAL 76 -0.06 ARG 37

GLU 14 0.05 ILE 77 -0.06 ARG 37

GLU 14 0.04 PRO 78 -0.06 ALA 165

GLU 14 0.03 LEU 79 -0.07 ALA 165

GLU 14 0.03 ASN 80 -0.06 ALA 165

LYS 21 0.03 LEU 81 -0.05 GLU 166

LYS 21 0.03 THR 82 -0.05 PRO 64

THR 271 0.03 LEU 83 -0.05 LYS 118

LEU 272 0.03 ASP 84 -0.05 LYS 118

ASN 111 0.04 ASN 85 -0.06 ASP 120

ASN 111 0.06 ARG 86 -0.05 TRP 123

ASN 111 0.05 VAL 87 -0.04 ASP 27

LYS 102 0.06 ALA 88 -0.05 SER 92

LYS 103 0.07 ASP 89 -0.05 SER 92

LYS 103 0.06 GLN 90 -0.04 ASP 24

THR 133 0.06 LEU 91 -0.04 ILE 25

THR 133 0.07 TRP 92 -0.04 GLY 25

ASN 54 0.07 VAL 93 -0.04 SER 92

ASN 54 0.08 PRO 94 -0.04 VAL 108

ASN 54 0.09 ASP 95 -0.05 ASN 88

ASN 54 0.09 THR 96 -0.08 VAL 108

ASN 54 0.11 TYR 97 -0.10 VAL 108

ASN 54 0.12 PHE 98 -0.12 VAL 108

ASN 54 0.13 LEU 99 -0.10 VAL 108

ASN 54 0.14 ASN 100 -0.12 VAL 108

ASN 54 0.15 ASP 101 -0.17 VAL 108

ASN 54 0.18 LYS 102 -0.23 VAL 108

ASN 54 0.18 LYS 103 -0.28 VAL 108

ASN 54 0.15 SER 104 -0.22 VAL 108

LYS 102 0.14 PHE 105 -0.18 VAL 108

PHE 105 0.08 VAL 106 -0.14 TRP 123

PHE 105 0.09 HIS 107 -0.14 ASP 120

PHE 105 0.09 GLY 108 -0.13 ASP 120

PHE 66 0.07 VAL 109 -0.13 LYS 118

PHE 66 0.07 THR 110 -0.12 LYS 118

PHE 105 0.05 VAL 111 -0.10 LYS 118

ALA 109 0.06 LYS 112 -0.10 ASP 120

LEU 272 0.04 ASN 113 -0.10 ASP 120

MET 115 0.04 ARG 114 -0.09 TRP 123

ARG 114 0.04 MET 115 -0.07 TRP 123

THR 271 0.04 ILE 116 -0.05 GLY 63

THR 271 0.03 ARG 117 -0.05 PRO 64

THR 271 0.03 LEU 118 -0.05 VAL 340

ASP 10 0.03 HIS 119 -0.05 ARG 169

ASP 10 0.04 PRO 120 -0.05 VAL 340

ASP 10 0.06 ASP 121 -0.05 ARG 169

ASP 10 0.05 GLY 122 -0.05 ARG 68

ASP 10 0.05 THR 123 -0.06 GLY 39

THR 271 0.04 VAL 124 -0.05 VAL 108

THR 271 0.04 LEU 125 -0.06 VAL 108

THR 271 0.05 TYR 126 -0.07 VAL 108

THR 271 0.05 GLY 127 -0.08 VAL 108

LEU 272 0.06 LEU 128 -0.10 VAL 108

LEU 272 0.06 ARG 129 -0.11 VAL 108

LYS 106 0.08 ILE 130 -0.14 VAL 108

LYS 106 0.11 THR 131 -0.16 VAL 108

ASN 54 0.12 THR 132 -0.19 VAL 108

ASN 54 0.16 THR 133 -0.19 VAL 108

ASN 54 0.15 ALA 134 -0.16 VAL 108

THR 271 0.16 ALA 135 -0.15 THR 61

THR 271 0.16 CYS 136 -0.12 PRO 52

THR 271 0.17 MET 137 -0.14 PRO 52

THR 271 0.17 MET 138 -0.12 HIS 56

THR 271 0.16 ASP 139 -0.11 HIS 56

HIS 267 0.17 LEU 140 -0.13 HIS 56

HIS 267 0.17 ARG 141 -0.10 HIS 56

HIS 267 0.14 ARG 142 -0.11 HIS 56

HIS 267 0.16 TYR 143 -0.13 HIS 56

GLU 270 0.15 PRO 144 -0.15 SER 276

GLU 270 0.12 LEU 145 -0.12 SER 276

GLU 270 0.12 ASP 146 -0.12 HIS 56

GLU 270 0.11 GLU 147 -0.12 HIS 56

THR 271 0.12 GLN 148 -0.12 HIS 56

THR 271 0.12 ASN 149 -0.11 HIS 56

THR 271 0.13 CYS 150 -0.12 PRO 52

THR 271 0.12 THR 151 -0.10 VAL 108

THR 271 0.11 LEU 152 -0.11 VAL 108

THR 271 0.11 GLU 153 -0.10 VAL 108

THR 271 0.10 ILE 154 -0.09 VAL 108

THR 271 0.10 GLU 155 -0.07 VAL 108

ASN 54 0.09 SER 156 -0.06 VAL 108

ASN 54 0.10 TYR 157 -0.04 LEU 118

ASN 54 0.10 GLY 158 -0.03 LEU 118

ASN 54 0.09 TYR 159 -0.03 GLY 208

THR 271 0.09 THR 160 -0.03 TYR 159

THR 271 0.08 THR 161 -0.03 VAL 108

MET 81 0.08 ASP 162 -0.03 GLY 25

THR 271 0.08 ASP 163 -0.03 GLY 25

THR 271 0.08 ILE 164 -0.03 VAL 108

THR 271 0.08 GLU 165 -0.04 VAL 108

THR 271 0.08 PHE 166 -0.06 VAL 108

THR 271 0.07 TYR 167 -0.06 VAL 108

THR 271 0.07 TRP 168 -0.07 VAL 108

THR 271 0.06 ARG 169 -0.07 GLY 208

THR 271 0.05 GLY 170 -0.08 GLY 208

THR 271 0.06 ASP 171 -0.07 SER 206

THR 271 0.05 ASP 172 -0.08 SER 206

THR 271 0.05 ASN 173 -0.11 SER 206

THR 271 0.06 ALA 174 -0.10 SER 206

ASP 57 0.06 VAL 175 -0.10 SER 206

ASP 57 0.05 THR 176 -0.11 SER 206

ASP 57 0.05 GLY 177 -0.11 PRO 64

ASP 57 0.06 VAL 178 -0.11 PRO 64

GLN 314 0.05 THR 179 -0.11 PRO 64

GLN 314 0.05 LYS 180 -0.13 PRO 64

ASP 57 0.06 ILE 181 -0.14 PRO 64

ARG 317 0.05 GLU 182 -0.15 SER 286

HIS 56 0.08 LEU 183 -0.16 PRO 64

LYS 279 0.10 PRO 184 -0.19 SER 286

LYS 279 0.12 GLN 185 -0.17 HIS 56

LYS 279 0.08 PHE 186 -0.16 HIS 56

LYS 279 0.08 SER 187 -0.14 HIS 56

HIS 56 0.07 ILE 188 -0.12 HIS 56

THR 271 0.06 VAL 189 -0.11 HIS 56

THR 271 0.07 ASP 190 -0.10 HIS 56

THR 271 0.07 TYR 191 -0.10 HIS 56

THR 271 0.08 LYS 192 -0.08 VAL 108

THR 271 0.08 LEU 193 -0.08 VAL 108

THR 271 0.08 ILE 194 -0.07 VAL 108

THR 271 0.08 THR 195 -0.06 VAL 108

THR 271 0.09 LYS 196 -0.05 VAL 108

THR 271 0.10 LYS 197 -0.04 VAL 108

THR 271 0.10 VAL 198 -0.04 VAL 108

THR 271 0.10 VAL 199 -0.03 ASP 63

THR 271 0.11 PHE 200 -0.02 GLY 208

THR 271 0.11 SER 201 -0.02 GLY 208

THR 271 0.10 THR 202 -0.02 GLY 208

THR 271 0.10 GLY 203 -0.02 GLY 208

THR 271 0.10 SER 204 -0.02 GLY 208

THR 271 0.10 TYR 205 -0.03 VAL 108

THR 271 0.09 PRO 206 -0.05 VAL 108

THR 271 0.10 ARG 207 -0.07 VAL 108

THR 271 0.09 LEU 208 -0.08 VAL 108

THR 271 0.10 SER 209 -0.09 VAL 108

THR 271 0.09 LEU 210 -0.10 VAL 108

THR 271 0.10 SER 211 -0.10 VAL 108

THR 271 0.10 PHE 212 -0.11 HIS 56

THR 271 0.10 LYS 213 -0.12 HIS 56

GLU 270 0.09 LEU 214 -0.14 HIS 56

GLU 270 0.08 LYS 215 -0.13 HIS 56

GLU 270 0.09 ARG 216 -0.15 HIS 56

LYS 279 0.08 ASN 217 -0.15 ASN 275

PHE 310 0.08 ILE 218 -0.16 ASN 275

PHE 310 0.08 GLY 219 -0.18 TYR 282

SER 299 0.09 TYR 220 -0.19 SER 286

THR 266 0.10 PHE 221 -0.20 ASN 275

PHE 310 0.08 ILE 222 -0.18 ASN 275

PHE 298 0.10 LEU 223 -0.19 ILE 282

ILE 271 0.13 GLN 224 -0.21 ILE 282

THR 266 0.14 THR 225 -0.20 SER 272

THR 263 0.12 TYR 226 -0.17 SER 272

THR 267 0.12 MET 227 -0.16 ILE 282

THR 267 0.18 PRO 228 -0.18 THR 275

LEU 259 0.17 SER 229 -0.18 MET 261

LEU 264 0.13 ILE 230 -0.14 SER 272

LEU 264 0.17 LEU 231 -0.16 THR 275

LEU 264 0.19 ILE 232 -0.16 THR 275

ALA 252 0.17 THR 233 -0.13 ALA 295

VAL 260 0.19 ILE 234 -0.17 ALA 295

VAL 260 0.29 LEU 235 -0.18 ALA 295

ALA 252 0.23 SER 236 -0.14 ALA 295

VAL 252 0.23 TRP 237 -0.14 ALA 295

THR 256 0.30 VAL 238 -0.21 ILE 302

PRO 253 0.30 SER 239 -0.19 ILE 302

VAL 252 0.30 PHE 240 -0.16 ILE 302

VAL 252 0.38 TRP 241 -0.25 THR 306

VAL 252 0.47 ILE 242 -0.38 TYR 309

VAL 252 0.38 ASN 243 -0.44 TYR 309

ALA 248 0.32 TYR 244 -0.32 TYR 309

ALA 246 0.36 ASP 245 -0.39 TYR 309

ALA 248 0.47 ALA 246 -0.41 TYR 309

ALA 248 0.48 SER 247 -0.31 TYR 309

ALA 248 0.59 ALA 248 -0.28 TYR 309

ALA 248 0.52 ALA 249 -0.30 ALA 305

ALA 248 0.41 ARG 250 -0.25 ALA 305

ALA 248 0.42 VAL 251 -0.20 TYR 309

ALA 252 0.52 ALA 252 -0.20 ALA 305

ALA 252 0.40 LEU 253 -0.19 ILE 302

ALA 252 0.34 GLY 254 -0.15 ILE 302

ALA 252 0.36 ILE 255 -0.13 ILE 247

THR 256 0.41 THR 256 -0.17 ILE 247

THR 256 0.31 THR 257 -0.14 ILE 232

THR 256 0.29 VAL 258 -0.12 PRO 243

THR 256 0.35 LEU 259 -0.19 THR 265

LEU 259 0.36 THR 260 -0.17 PRO 243

THR 263 0.29 MET 261 -0.18 SER 229

THR 263 0.32 THR 262 -0.17 SER 272

THR 263 0.41 THR 263 -0.25 SER 272

THR 263 0.35 ILE 264 -0.22 SER 272

THR 263 0.30 ASN 265 -0.20 SER 272

HIS 267 0.36 THR 266 -0.32 SER 272

HIS 267 0.42 HIS 267 -0.30 SER 272

HIS 267 0.34 LEU 268 -0.23 SER 276

HIS 267 0.32 ARG 269 -0.24 SER 276

HIS 267 0.35 GLU 270 -0.34 SER 276

GLU 270 0.33 THR 271 -0.26 SER 276

THR 271 0.28 LEU 272 -0.20 HIS 56

THR 271 0.26 PRO 273 -0.21 HIS 56

THR 271 0.25 LYS 274 -0.16 HIS 56

HIS 267 0.22 ILE 275 -0.11 HIS 56

HIS 267 0.21 PRO 276 -0.08 ARG 194

HIS 267 0.20 TYR 277 -0.07 ARG 194

HIS 267 0.20 VAL 278 -0.07 ARG 194

HIS 267 0.19 LYS 279 -0.10 SER 276

HIS 267 0.17 ALA 280 -0.11 SER 276

HIS 267 0.19 ILE 281 -0.14 SER 276

HIS 267 0.21 ASP 282 -0.13 SER 276

THR 263 0.18 MET 283 -0.10 SER 276

THR 263 0.18 TYR 284 -0.11 SER 276

THR 263 0.22 LEU 285 -0.13 SER 272

THR 263 0.20 MET 286 -0.10 SER 276

THR 256 0.18 GLY 287 -0.09 SER 276

THR 256 0.20 CYS 288 -0.10 SER 272

THR 256 0.22 PHE 289 -0.10 SER 272

THR 256 0.20 VAL 290 -0.07 TRP 288

ALA 252 0.20 PHE 291 -0.08 TRP 288

ALA 252 0.24 VAL 292 -0.10 ALA 295

ALA 252 0.24 PHE 293 -0.09 ALA 295

ALA 252 0.22 MET 294 -0.09 ALA 295

ALA 248 0.25 ALA 295 -0.11 ALA 295

ALA 248 0.28 LEU 296 -0.11 ALA 295

ALA 248 0.25 LEU 297 -0.09 ALA 295

ALA 248 0.26 GLU 298 -0.09 ALA 295

ALA 248 0.30 TYR 299 -0.13 TYR 309

ALA 248 0.29 ALA 300 -0.15 TYR 309

ALA 248 0.26 LEU 301 -0.12 TYR 309

ALA 248 0.28 VAL 302 -0.15 TYR 309

ALA 248 0.31 ASN 303 -0.20 TYR 309

ALA 246 0.27 TYR 304 -0.16 TYR 309

ALA 246 0.27 ILE 305 -0.15 TYR 309

ALA 246 0.30 PHE 306 -0.20 SER 313

ALA 246 0.31 PHE 307 -0.23 SER 313

ALA 246 0.27 SER 308 -0.18 SER 313

ASP 245 0.26 GLN 309 -0.15 SER 313

ASP 245 0.27 PRO 310 -0.16 SER 313

ASP 245 0.24 ALA 311 -0.09 THR 306

ALA 246 0.23 ARG 312 -0.08 THR 306

ALA 248 0.25 ALA 313 -0.11 TYR 309

ALA 248 0.23 ALA 314 -0.12 THR 306

ALA 248 0.20 ALA 315 -0.08 LEU 332

ALA 248 0.22 ILE 316 -0.08 ALA 295

VAL 252 0.24 ASP 317 -0.10 THR 306

VAL 252 0.24 ARG 318 -0.10 LEU 332

VAL 252 0.20 TRP 319 -0.10 LEU 332

VAL 252 0.21 SER 320 -0.10 ALA 295

VAL 252 0.24 ARG 321 -0.11 ALA 295

VAL 252 0.20 ILE 322 -0.12 LEU 332

VAL 252 0.18 PHE 323 -0.11 VAL 339

VAL 252 0.18 PHE 324 -0.10 ALA 295

VAL 252 0.18 PRO 325 -0.12 VAL 339

VAL 252 0.16 VAL 326 -0.12 VAL 339

ALA 248 0.15 VAL 327 -0.10 VAL 339

ALA 252 0.15 PHE 328 -0.10 VAL 339

VAL 252 0.15 SER 329 -0.12 THR 343

VAL 252 0.13 PHE 330 -0.11 THR 343

ALA 252 0.14 PHE 331 -0.09 THR 343

ALA 252 0.13 ASN 332 -0.10 THR 343

VAL 252 0.12 ILE 333 -0.11 THR 343

ALA 252 0.12 VAL 334 -0.10 THR 343

THR 256 0.12 TYR 335 -0.09 THR 343

VAL 252 0.11 TRP 336 -0.10 THR 343

SER 313 0.10 LEU 337 -0.10 THR 343

THR 263 0.11 TYR 338 -0.08 THR 343

THR 263 0.11 TYR 339 -0.09 SER 276

THR 263 0.10 VAL 340 -0.11 VAL 189

LYS 70 0.07 ASP 10 -0.07 GLY 22

PRO 34 0.06 ASN 11 -0.06 GLY 22

LYS 70 0.05 THR 12 -0.07 GLY 22

ASN 346 0.05 THR 13 -0.07 GLY 22

ASN 346 0.05 VAL 14 -0.06 ASP 24

ASN 346 0.05 PHE 15 -0.06 ASP 24

ASN 346 0.05 THR 16 -0.07 ASP 24

ASP 20 0.05 ARG 17 -0.07 ARG 17

ASN 346 0.05 ILE 18 -0.07 ARG 17

THR 271 0.05 LEU 19 -0.07 ARG 17

ARG 17 0.05 ASP 20 -0.08 ARG 17

ARG 17 0.05 ARG 21 -0.08 ARG 17

ASN 346 0.05 LEU 22 -0.07 ARG 17

ASN 54 0.04 LEU 23 -0.07 ARG 17

GLY 25 0.05 ASP 24 -0.08 ARG 17

GLY 25 0.07 GLY 25 -0.08 THR 13

SER 229 0.04 TYR 26 -0.07 ARG 17

LEU 98 0.04 ASP 27 -0.07 ARG 17

THR 133 0.04 ASN 28 -0.06 PHE 105

THR 225 0.04 ARG 29 -0.07 PHE 105

SER 195 0.05 LEU 30 -0.06 PHE 105

SER 195 0.05 ARG 31 -0.06 PHE 105

SER 195 0.06 PRO 32 -0.06 GLY 25

SER 195 0.06 GLY 33 -0.08 GLY 25

ASP 192 0.06 LEU 34 -0.09 VAL 27

ASP 192 0.06 GLY 35 -0.11 ASP 26

ASP 192 0.06 GLU 36 -0.08 ASP 26

SER 195 0.07 ARG 37 -0.09 THR 92

SER 195 0.08 VAL 38 -0.09 ILE 93

SER 195 0.07 THR 39 -0.06 ILE 93

SER 195 0.08 GLU 40 -0.06 ILE 93

SER 51 0.07 VAL 41 -0.05 ALA 109

VAL 53 0.08 LYS 42 -0.05 ALA 109

VAL 53 0.09 THR 43 -0.05 ALA 109

VAL 53 0.10 ASP 44 -0.04 LYS 102

VAL 53 0.11 ILE 45 -0.08 PHE 46

ASN 54 0.13 PHE 46 -0.08 ILE 45

VAL 53 0.14 VAL 47 -0.05 ASP 63

ASN 54 0.15 THR 48 -0.03 CYS 150

VAL 53 0.17 SER 49 -0.06 CYS 150

VAL 53 0.17 PHE 50 -0.07 CYS 150

VAL 53 0.19 GLY 51 -0.13 MET 55

VAL 53 0.21 PRO 52 -0.19 MET 55

VAL 53 0.19 VAL 53 -0.18 ASN 54

SER 51 0.21 SER 54 -0.24 VAL 53

LYS 285 0.18 ASP 55 -0.25 VAL 53

LYS 285 0.21 HIS 56 -0.28 VAL 53

MET 49 0.18 ASP 57 -0.25 VAL 53

SER 286 0.15 MET 58 -0.21 VAL 53

MET 49 0.15 GLU 59 -0.22 ASN 54

SER 51 0.16 TYR 60 -0.20 ASN 54

SER 51 0.17 THR 61 -0.18 ASN 54

ASN 54 0.16 ILE 62 -0.10 ASN 54

ASN 54 0.17 ASP 63 -0.07 CYS 150

ASN 54 0.14 VAL 64 -0.05 THR 133

ASN 54 0.13 PHE 65 -0.04 THR 133

ASN 54 0.11 PHE 66 -0.05 LYS 102

ASN 54 0.10 ARG 67 -0.04 ALA 109

ASN 54 0.09 GLN 68 -0.05 ALA 109

ASN 54 0.08 SER 69 -0.04 ALA 109

VAL 53 0.07 TRP 70 -0.04 ALA 109

VAL 53 0.06 LYS 71 -0.04 GLY 25

SER 229 0.06 ASP 72 -0.05 ARG 17

SER 195 0.06 GLU 73 -0.05 ASP 10

SER 229 0.05 ARG 74 -0.06 ARG 17

ASN 54 0.05 LEU 75 -0.06 ARG 17

ASN 346 0.06 LYS 76 -0.06 ARG 17

ASN 346 0.06 PHE 77 -0.06 ARG 17

ASN 346 0.06 LYS 78 -0.06 ARG 17

PRO 34 0.07 GLY 79 -0.06 ARG 17

PRO 34 0.09 PRO 80 -0.05 ARG 17

PRO 34 0.08 MET 81 -0.05 ARG 17

ASN 346 0.07 THR 82 -0.04 ARG 17

THR 271 0.08 VAL 83 -0.04 ARG 17

ASN 54 0.07 LEU 84 -0.04 ARG 17

ASN 54 0.08 ARG 85 -0.03 ARG 17

ASN 54 0.08 LEU 86 -0.04 ARG 17

THR 133 0.08 ASN 87 -0.03 ASP 95

THR 133 0.09 ASN 88 -0.05 ASP 95

THR 133 0.08 LEU 89 -0.05 MET 114

THR 133 0.07 MET 90 -0.04 ARG 17

THR 133 0.08 ALA 91 -0.06 PRO 115

THR 133 0.07 SER 92 -0.07 PHE 105

THR 133 0.06 LYS 93 -0.06 PHE 105

THR 133 0.06 ILE 94 -0.06 PHE 105

THR 133 0.06 TRP 95 -0.07 PHE 105

THR 133 0.07 THR 96 -0.07 PHE 105

THR 133 0.07 PRO 97 -0.08 ALA 109

TRP 123 0.08 ASP 98 -0.10 ALA 109

HIS 122 0.09 THR 99 -0.12 ALA 109

HIS 122 0.10 PHE 100 -0.11 LYS 103

MET 49 0.10 PHE 101 -0.12 LYS 103

GLY 63 0.10 HIS 102 -0.11 LYS 103

GLY 63 0.12 ASN 103 -0.13 ASN 54

MET 49 0.12 GLY 104 -0.14 LYS 103

ASP 48 0.15 LYS 105 -0.16 LYS 103

ASP 48 0.16 LYS 106 -0.21 LYS 103

THR 133 0.15 SER 107 -0.23 LYS 103

THR 133 0.16 VAL 108 -0.28 LYS 103

LYS 103 0.17 ALA 109 -0.21 THR 125

LYS 103 0.16 HIS 110 -0.15 VAL 108

LYS 103 0.14 ASN 111 -0.11 THR 125

LYS 103 0.12 MET 112 -0.10 VAL 108

LYS 102 0.10 THR 113 -0.08 VAL 108

LYS 103 0.10 MET 114 -0.07 SER 92

LYS 103 0.12 PRO 115 -0.08 THR 125

LYS 103 0.12 ASN 116 -0.05 THR 125

THR 133 0.11 LYS 117 -0.05 THR 96

THR 133 0.10 LEU 118 -0.04 TYR 157

THR 133 0.08 LEU 119 -0.04 LYS 117

ASN 54 0.08 ARG 120 -0.03 ARG 17

ASN 54 0.07 ILE 121 -0.04 ARG 17

THR 271 0.07 THR 122 -0.04 ARG 17

ASN 346 0.07 GLU 123 -0.05 ARG 17

ASN 346 0.07 ASP 124 -0.05 ARG 17

VAL 53 0.06 GLY 125 -0.05 ARG 17

VAL 53 0.07 THR 126 -0.04 ARG 17

ASN 54 0.08 LEU 127 -0.03 ARG 17

ASN 54 0.09 LEU 128 -0.03 ARG 17

THR 133 0.09 TYR 129 -0.04 LYS 117

ASN 54 0.10 THR 130 -0.03 ALA 109

THR 133 0.12 MET 131 -0.05 LYS 103

THR 133 0.13 ARG 132 -0.06 LEU 99

THR 133 0.15 LEU 133 -0.11 LYS 102

THR 133 0.16 THR 134 -0.15 LYS 102

THR 133 0.16 VAL 135 -0.12 LYS 102

MET 49 0.17 ARG 136 -0.18 LYS 102

MET 49 0.14 ALA 137 -0.16 ASN 54

MET 49 0.13 GLU 138 -0.16 ASN 54

LYS 285 0.12 CYS 139 -0.15 ASN 54

SER 286 0.14 PRO 140 -0.24 SER 195

SER 286 0.14 MET 141 -0.19 SER 195

SER 286 0.14 HIS 142 -0.18 ARG 194

SER 286 0.14 LEU 143 -0.16 ARG 194

SER 286 0.13 GLU 144 -0.13 ARG 194

ILE 282 0.14 ASP 145 -0.13 ARG 194

ILE 282 0.16 PHE 146 -0.13 ARG 194

THR 225 0.16 PRO 147 -0.11 ARG 194

SER 229 0.15 MET 148 -0.10 ARG 194

THR 225 0.14 ASP 149 -0.11 ARG 194

THR 225 0.13 ALA 150 -0.10 ASP 192

THR 225 0.13 HIS 151 -0.10 ASP 192

HIS 216 0.15 ALA 152 -0.09 VAL 53

SER 51 0.12 CYS 153 -0.11 ASN 54

SER 286 0.12 PRO 154 -0.11 ASN 54

MET 49 0.11 LEU 155 -0.11 ASN 54

MET 49 0.10 LYS 156 -0.10 ASN 54

MET 49 0.09 PHE 157 -0.10 LYS 103

SER 195 0.08 GLY 158 -0.09 LYS 103

SER 195 0.07 SER 159 -0.09 LYS 103

ARG 144 0.06 TYR 160 -0.10 LYS 103

PHE 77 0.06 ALA 161 -0.09 PHE 105

SER 195 0.07 TYR 162 -0.08 LYS 103

ASP 192 0.09 THR 163 -0.09 VAL 95

SER 195 0.10 ARG 164 -0.09 LYS 94

ASP 192 0.09 ALA 165 -0.11 ILE 93

SER 195 0.07 GLU 166 -0.09 ILE 93

SER 195 0.08 VAL 167 -0.07 LYS 103

SER 195 0.09 VAL 168 -0.06 ILE 93

SER 195 0.08 TYR 169 -0.06 LYS 103

SER 195 0.08 GLU 170 -0.05 LYS 103

VAL 53 0.09 TRP 171 -0.04 LYS 103

VAL 53 0.09 THR 172 -0.04 ILE 93

VAL 53 0.09 ARG 173 -0.04 THR 92

ARG 347 0.10 GLU 174 -0.04 THR 92

ARG 347 0.10 PRO 175 -0.04 THR 92

ARG 347 0.12 ALA 176 -0.04 THR 92

ARG 347 0.11 ARG 177 -0.03 THR 92

VAL 53 0.11 SER 178 -0.03 ILE 93

VAL 53 0.12 VAL 179 -0.03 ASP 199

VAL 53 0.13 VAL 180 -0.03 ASP 199

THR 271 0.14 VAL 181 -0.04 VAL 198

THR 271 0.14 ALA 182 -0.03 VAL 198

THR 271 0.15 GLU 183 -0.03 ASP 192

THR 271 0.16 ASP 184 -0.04 ASP 192

THR 271 0.16 GLY 185 -0.04 ASP 192

THR 271 0.18 SER 186 -0.05 ASP 192

THR 271 0.20 ARG 187 -0.07 PRO 52

THR 271 0.21 LEU 188 -0.08 SER 195

THR 271 0.23 ASN 189 -0.09 SER 195

THR 271 0.21 GLN 190 -0.09 SER 195

THR 271 0.18 TYR 191 -0.08 ASP 192

THR 271 0.17 ASP 192 -0.06 ASP 192

THR 271 0.15 LEU 193 -0.05 ASP 192

THR 271 0.14 LEU 194 -0.05 ASP 192

THR 271 0.13 GLY 195 -0.04 SER 186

VAL 53 0.12 GLN 196 -0.05 ASN 54

THR 225 0.11 THR 197 -0.05 ASN 54

THR 225 0.10 VAL 198 -0.06 ASN 54

SER 195 0.13 ASP 199 -0.06 ASN 54

SER 195 0.13 SER 200 -0.06 ASN 54

SER 195 0.14 GLY 201 -0.07 ASN 54

SER 195 0.13 ILE 202 -0.07 ASN 54

ASP 192 0.15 VAL 203 -0.08 ASN 54

ASP 192 0.15 GLN 204 -0.08 ASN 54

GLY 191 0.14 SER 205 -0.09 ASN 54

GLY 191 0.11 SER 206 -0.09 SER 51

GLY 191 0.08 THR 207 -0.09 LEU 140

GLY 191 0.12 GLY 208 -0.09 TRP 134

ASP 192 0.12 GLU 209 -0.08 LYS 94

SER 195 0.11 TYR 210 -0.08 LYS 103

SER 195 0.11 VAL 211 -0.07 LYS 103

SER 195 0.12 VAL 212 -0.08 ASN 54

SER 195 0.10 MET 213 -0.08 ASN 54

SER 195 0.11 THR 214 -0.08 ASN 54

SER 51 0.11 THR 215 -0.08 ASN 54

ALA 152 0.15 HIS 216 -0.08 ASN 54

VAL 53 0.13 PHE 217 -0.07 ASN 54

THR 225 0.13 HIS 218 -0.07 VAL 53

THR 271 0.14 LEU 219 -0.07 ASP 192

THR 271 0.15 LYS 220 -0.08 ASP 192

HIS 267 0.16 ARG 221 -0.09 ARG 194

HIS 267 0.18 LYS 222 -0.09 ARG 194

HIS 267 0.19 ILE 223 -0.09 ARG 194

HIS 267 0.21 GLY 224 -0.08 ARG 194

HIS 267 0.24 TYR 225 -0.09 ARG 194

HIS 267 0.22 PHE 226 -0.10 ARG 194

HIS 267 0.21 VAL 227 -0.08 ARG 194

HIS 267 0.24 ILE 228 -0.08 ARG 194

HIS 267 0.26 GLN 229 -0.09 ARG 194

ILE 264 0.22 THR 230 -0.09 ARG 194

SER 229 0.19 TYR 231 -0.08 ARG 194

THR 260 0.20 LEU 232 -0.07 ARG 194

THR 260 0.23 PRO 233 -0.08 ILE 238

SER 229 0.20 CYS 234 -0.08 ARG 194

ILE 232 0.18 ILE 235 -0.06 ARG 194

THR 256 0.20 MET 236 -0.06 ARG 194

ILE 232 0.21 THR 237 -0.08 ALA 295

LEU 235 0.19 VAL 238 -0.09 LYS 312

ALA 249 0.19 ILE 239 -0.08 TYR 309

ALA 249 0.23 LEU 240 -0.10 TYR 309

ALA 249 0.21 SER 241 -0.12 TYR 309

ALA 249 0.19 GLN 242 -0.12 TYR 309

ALA 249 0.22 VAL 243 -0.12 TYR 309

ALA 249 0.24 SER 244 -0.16 TYR 309

ALA 249 0.20 PHE 245 -0.16 SER 313

ALA 249 0.22 TRP 246 -0.15 TYR 309

ALA 249 0.26 LEU 247 -0.20 TYR 309

ALA 246 0.25 ASN 248 -0.24 SER 313

ALA 246 0.23 ARG 249 -0.26 SER 313

ALA 246 0.28 GLU 250 -0.32 LYS 312

ALA 246 0.34 SER 251 -0.32 LYS 312

ALA 249 0.30 VAL 252 -0.31 LYS 312

ALA 249 0.41 PRO 253 -0.32 PRO 253

ALA 249 0.40 ALA 254 -0.27 TYR 309

ALA 249 0.30 ARG 255 -0.23 TYR 309

ALA 249 0.28 THR 256 -0.24 LYS 312

ALA 249 0.33 VAL 257 -0.22 THR 256

ALA 249 0.29 PHE 258 -0.19 TYR 309

LEU 235 0.24 GLY 259 -0.17 LYS 312

LEU 235 0.27 VAL 260 -0.19 LEU 250

LEU 235 0.27 THR 261 -0.19 LEU 264

LEU 235 0.24 THR 262 -0.14 TYR 309

LEU 235 0.24 VAL 263 -0.16 LEU 264

ILE 232 0.28 LEU 264 -0.20 LEU 264

ILE 232 0.25 THR 265 -0.19 LEU 259

PRO 228 0.22 MET 266 -0.13 THR 267

PRO 228 0.25 THR 267 -0.20 PRO 243

PRO 228 0.28 THR 268 -0.21 THR 263

PRO 228 0.23 LEU 269 -0.20 THR 263

PRO 228 0.22 SER 270 -0.18 ILE 238

ILE 282 0.25 ILE 271 -0.23 HIS 267

THR 225 0.24 SER 272 -0.32 THR 266

THR 225 0.20 ALA 273 -0.23 THR 266

ILE 282 0.22 ARG 274 -0.21 HIS 267

ILE 282 0.27 ASN 275 -0.27 GLU 270

LYS 285 0.21 SER 276 -0.34 GLU 270

LYS 285 0.19 LEU 277 -0.25 GLU 270

SER 286 0.22 PRO 278 -0.23 GLU 270

SER 286 0.25 LYS 279 -0.19 LYS 279

SER 286 0.18 VAL 280 -0.17 GLU 270

SER 286 0.14 ALA 281 -0.16 LYS 279

SER 286 0.12 TYR 282 -0.14 LYS 279

SER 286 0.13 ALA 283 -0.13 GLU 270

ILE 282 0.13 THR 284 -0.12 GLU 270

PRO 228 0.14 ALA 285 -0.10 ARG 194

PRO 228 0.16 MET 286 -0.11 GLU 270

ILE 282 0.16 ASP 287 -0.12 GLU 270

PRO 228 0.14 TRP 288 -0.09 GLU 270

PRO 228 0.15 PHE 289 -0.08 ALA 281

PRO 228 0.17 ILE 290 -0.09 THR 266

PRO 228 0.15 ALA 291 -0.10 LYS 312

PRO 228 0.14 VAL 292 -0.10 LYS 312

PRO 228 0.17 CYS 293 -0.10 LYS 312

PRO 228 0.18 TYR 294 -0.12 LYS 312

PRO 228 0.15 ALA 295 -0.12 LYS 312

LEU 235 0.16 PHE 296 -0.12 LYS 312

LEU 235 0.19 VAL 297 -0.13 LYS 312

LEU 235 0.17 PHE 298 -0.16 LYS 312

LEU 235 0.15 SER 299 -0.15 LYS 312

LEU 235 0.17 ALA 300 -0.16 LYS 312

LEU 235 0.19 LEU 301 -0.19 LYS 312

VAL 238 0.15 ILE 302 -0.19 LYS 312

VAL 238 0.15 GLU 303 -0.19 LYS 312

VAL 238 0.18 PHE 304 -0.21 LYS 312

VAL 238 0.17 ALA 305 -0.23 LYS 312

VAL 238 0.14 THR 306 -0.22 LYS 312

VAL 238 0.15 VAL 307 -0.23 LYS 312

TRP 241 0.17 ASN 308 -0.27 LYS 312

TRP 241 0.14 TYR 309 -0.28 LYS 312

ILE 322 0.13 PHE 310 -0.26 LYS 312

TRP 241 0.15 THR 311 -0.29 LYS 312

TRP 241 0.14 LYS 312 -0.32 LYS 312

ILE 322 0.12 SER 313 -0.29 LYS 312

ILE 322 0.11 GLN 314 -0.26 LYS 312

TRP 241 0.13 PRO 315 -0.26 SER 313

TRP 241 0.12 ALA 316 -0.22 SER 313

ILE 322 0.11 ARG 317 -0.21 SER 313

TRP 241 0.13 ALA 318 -0.22 SER 313

ILE 242 0.14 ALA 319 -0.20 SER 313

ILE 242 0.12 LYS 320 -0.18 SER 313

VAL 238 0.13 ILE 321 -0.18 SER 313

ILE 242 0.15 ASP 322 -0.18 SER 313

ALA 246 0.14 ARG 323 -0.15 SER 313

SER 239 0.13 LEU 324 -0.14 SER 313

VAL 238 0.14 SER 325 -0.14 SER 313

ALA 249 0.16 ARG 326 -0.13 SER 313

ALA 249 0.15 ILE 327 -0.10 SER 313

SER 239 0.13 ALA 328 -0.11 SER 313

LEU 235 0.14 PHE 329 -0.10 SER 313

ALA 249 0.15 PRO 330 -0.08 SER 313

LEU 235 0.13 LEU 331 -0.07 SER 313

LEU 235 0.12 LEU 332 -0.08 LYS 312

LEU 235 0.14 PHE 333 -0.07 LYS 312

LEU 235 0.14 GLY 334 -0.05 ARG 194

LEU 235 0.12 ILE 335 -0.06 GLY 205

SER 229 0.12 PHE 336 -0.06 LYS 312

SER 229 0.14 ASN 337 -0.06 ARG 194

SER 229 0.13 LEU 338 -0.06 ARG 194

SER 229 0.11 VAL 339 -0.07 GLY 205

SER 229 0.12 TYR 340 -0.07 ARG 194

SER 229 0.14 TRP 341 -0.08 ARG 194

SER 229 0.12 ALA 342 -0.07 ASP 192

SER 229 0.11 THR 343 -0.08 ARG 194

SER 229 0.13 TYR 344 -0.09 ARG 194

SER 229 0.13 LEU 345 -0.08 ARG 194

LEU 194 0.12 ASN 346 -0.08 ASP 192

LEU 194 0.13 ARG 347 -0.09 ASP 192

GLY 25 0.07 GLY 25 -0.09 GLY 35

GLY 25 0.05 ASP 26 -0.11 GLY 35

GLY 25 0.05 VAL 27 -0.09 GLY 35

GLY 25 0.06 THR 28 -0.06 GLY 35

GLY 22 0.05 VAL 29 -0.07 GLY 35

GLY 22 0.05 ILE 30 -0.07 GLY 35

GLY 22 0.05 LEU 31 -0.06 LYS 21

GLY 22 0.06 ASN 32 -0.07 LYS 21

GLY 22 0.06 ASN 33 -0.07 LYS 21

GLY 22 0.05 LEU 34 -0.06 GLY 35

GLY 22 0.06 LEU 35 -0.07 LYS 21

GLY 22 0.07 GLU 36 -0.08 LYS 21

LYS 21 0.07 GLY 37 -0.09 ASP 17

LYS 21 0.06 TYR 38 -0.08 ASP 17

LYS 21 0.06 ASP 39 -0.08 ASP 17

LYS 21 0.06 ASN 40 -0.05 VAL 108

LYS 21 0.05 LYS 41 -0.05 VAL 108

LYS 21 0.05 LEU 42 -0.05 VAL 108

LYS 21 0.05 ARG 43 -0.06 LYS 106

LYS 21 0.04 PRO 44 -0.05 ASP 57

LYS 21 0.04 ASP 45 -0.05 ASP 57

LYS 21 0.05 ILE 46 -0.05 ASP 57

GLU 14 0.05 GLY 47 -0.05 ASP 57

GLU 14 0.04 VAL 48 -0.05 ASP 57

LYS 21 0.04 LYS 49 -0.06 ASP 57

LYS 21 0.04 PRO 50 -0.06 ASP 57

GLY 22 0.04 THR 51 -0.07 ASP 57

GLY 22 0.03 LEU 52 -0.08 ASP 57

GLY 22 0.03 ILE 53 -0.08 ASP 57

GLY 22 0.03 HIS 54 -0.09 ASP 57

VAL 340 0.03 THR 55 -0.10 ASP 57

ARG 132 0.03 ASP 56 -0.10 ASP 57

GLY 208 0.04 MET 57 -0.11 ASP 57

GLY 208 0.08 TYR 58 -0.13 SER 51

SER 205 0.08 VAL 59 -0.14 SER 51

VAL 203 0.11 ASN 60 -0.16 ASN 54

VAL 203 0.12 SER 61 -0.18 SER 51

VAL 203 0.09 ILE 62 -0.17 ASP 57

ASN 103 0.12 GLY 63 -0.19 ASP 57

PRO 140 0.12 PRO 64 -0.21 HIS 56

ASP 57 0.09 VAL 65 -0.21 HIS 56

ASP 57 0.15 ASN 66 -0.23 HIS 56

HIS 56 0.12 ALA 67 -0.22 HIS 56

PRO 184 0.19 ILE 68 -0.25 HIS 56

PRO 184 0.18 ASN 69 -0.23 HIS 56

GLU 182 0.14 MET 70 -0.21 HIS 56

ASP 57 0.11 GLU 71 -0.20 ASP 57

ASP 57 0.09 TYR 72 -0.19 ASP 57

ASN 103 0.10 THR 73 -0.19 ASP 57

ASN 103 0.09 ILE 74 -0.16 ASP 57

HIS 102 0.09 ASP 75 -0.15 MET 49

GLY 208 0.06 ILE 76 -0.13 MET 49

ALA 161 0.06 PHE 77 -0.12 MET 49

VAL 340 0.04 PHE 78 -0.11 LYS 106

VAL 340 0.04 ALA 79 -0.10 MET 49

VAL 340 0.03 GLN 80 -0.09 LYS 106

GLY 22 0.03 THR 81 -0.08 THR 207

GLY 22 0.03 TRP 82 -0.07 ASP 57

GLY 22 0.04 TYR 83 -0.07 THR 207

GLY 22 0.04 ASP 84 -0.06 GLY 208

GLY 22 0.04 ARG 85 -0.06 GLY 208

GLY 22 0.05 ARG 86 -0.06 GLY 208

GLY 22 0.05 LEU 87 -0.06 GLY 208

GLY 22 0.05 LYS 88 -0.06 SER 10

GLY 22 0.05 PHE 89 -0.06 ALA 165

GLY 22 0.04 ASN 90 -0.07 ALA 165

GLY 22 0.04 SER 91 -0.08 ALA 165

GLY 25 0.03 THR 92 -0.09 ALA 165

GLY 25 0.04 ILE 93 -0.11 ALA 165

GLY 25 0.03 LYS 94 -0.11 ALA 165

GLY 191 0.03 VAL 95 -0.10 ALA 165

ASP 27 0.04 LEU 96 -0.08 ALA 165

GLY 191 0.05 ARG 97 -0.07 PHE 105

ASP 27 0.04 LEU 98 -0.08 PHE 105

VAL 340 0.04 ASN 99 -0.09 PHE 105

VAL 340 0.04 SER 100 -0.09 PHE 105

VAL 340 0.04 ASN 101 -0.08 PHE 105

GLY 22 0.04 MET 102 -0.07 PHE 105

GLY 22 0.03 VAL 103 -0.08 VAL 106

GLY 22 0.04 GLY 104 -0.08 GLY 108

ILE 106 0.05 LYS 105 -0.07 GLY 108

LYS 105 0.05 ILE 106 -0.06 LYS 106

GLY 22 0.04 TRP 107 -0.07 LYS 106

GLY 22 0.04 ILE 108 -0.08 LYS 106

VAL 108 0.04 PRO 109 -0.08 LYS 106

VAL 108 0.06 ASP 110 -0.09 VAL 108

LYS 106 0.05 THR 111 -0.10 LYS 106

LYS 106 0.07 PHE 112 -0.11 LYS 106

LYS 106 0.08 PHE 113 -0.12 ASP 57

LYS 106 0.08 ARG 114 -0.12 ASP 57

GLY 177 0.10 ASN 115 -0.14 ASP 57

ALA 45 0.12 SER 116 -0.15 ASP 57

SER 46 0.17 LYS 117 -0.17 LYS 106

THR 60 0.14 LYS 118 -0.18 LYS 106

LYS 106 0.13 ALA 119 -0.17 LYS 106

LYS 106 0.15 ASP 120 -0.16 LYS 106

LYS 106 0.08 ALA 121 -0.14 PHE 105

PHE 100 0.10 HIS 122 -0.16 PHE 105

ILE 124 0.11 TRP 123 -0.17 PHE 105

TRP 123 0.11 ILE 124 -0.18 ALA 109

THR 133 0.09 THR 125 -0.21 ALA 109

TRP 123 0.08 THR 126 -0.13 PHE 105

GLY 108 0.08 PRO 127 -0.13 PHE 105

HIS 122 0.08 ASN 128 -0.12 PHE 105

GLY 108 0.05 ARG 129 -0.10 PHE 105

VAL 340 0.04 MET 130 -0.09 PHE 105

PHE 77 0.04 LEU 131 -0.08 PHE 105

PHE 77 0.04 ARG 132 -0.09 ILE 133

GLY 22 0.04 ILE 133 -0.09 ARG 132

GLY 22 0.03 TRP 134 -0.09 GLY 208

GLY 22 0.04 ASN 135 -0.08 GLY 208

GLY 22 0.04 ASP 136 -0.08 GLY 208

GLY 22 0.04 GLY 137 -0.07 GLY 208

GLY 22 0.03 ARG 138 -0.08 GLY 208

GLY 22 0.03 VAL 139 -0.07 THR 207

VAL 340 0.03 LEU 140 -0.09 THR 207

VAL 340 0.03 TYR 141 -0.09 LYS 106

VAL 340 0.04 THR 142 -0.10 PHE 105

VAL 340 0.04 LEU 143 -0.11 PHE 105

TYR 160 0.06 ARG 144 -0.13 PHE 105

HIS 102 0.06 LEU 145 -0.13 LYS 106

LYS 105 0.11 THR 146 -0.15 LYS 106

LYS 105 0.10 ILE 147 -0.16 LYS 106

LYS 105 0.11 ASP 148 -0.18 ASP 57

GLY 177 0.09 ALA 149 -0.17 ASP 57

GLU 182 0.10 GLU 150 -0.17 ASP 57

ASP 57 0.07 CYS 151 -0.17 HIS 56

ASP 57 0.08 GLN 152 -0.17 HIS 56

HIS 56 0.08 LEU 153 -0.18 HIS 56

HIS 56 0.07 GLN 154 -0.19 THR 271

HIS 56 0.08 LEU 155 -0.21 THR 271

HIS 56 0.06 HIS 156 -0.21 THR 271

ASP 199 0.05 ASN 157 -0.19 THR 271

ASP 199 0.06 PHE 158 -0.21 ASN 275

ASP 199 0.07 PRO 159 -0.22 ASN 275

ASP 199 0.06 MET 160 -0.20 ASN 275

ASP 199 0.06 ASP 161 -0.19 ASN 275

ASP 199 0.05 GLU 162 -0.17 ASN 275

ASP 199 0.05 HIS 163 -0.16 ASN 275

ASP 199 0.05 SER 164 -0.15 HIS 56

ASP 199 0.05 CYS 165 -0.15 HIS 56

ASP 199 0.04 PRO 166 -0.14 ASP 57

LYS 105 0.04 LEU 167 -0.14 ASP 57

ARG 136 0.04 GLU 168 -0.13 ASP 57

LYS 106 0.05 PHE 169 -0.11 ASP 57

LYS 106 0.05 SER 170 -0.10 ASP 57

LYS 106 0.05 SER 171 -0.08 ASP 57

LYS 106 0.07 TYR 172 -0.08 VAL 108

VAL 108 0.06 GLY 173 -0.07 VAL 108

VAL 108 0.05 TYR 174 -0.07 ASP 57

VAL 108 0.05 PRO 175 -0.07 ASP 57

VAL 108 0.04 ARG 176 -0.07 ASP 57

PRO 78 0.04 GLU 177 -0.06 ASP 57

LYS 21 0.04 GLU 178 -0.06 ASP 57

GLY 22 0.03 ILE 179 -0.07 ASP 57

GLY 22 0.03 VAL 180 -0.08 ASP 57

GLY 22 0.03 TYR 181 -0.09 ASP 57

GLY 22 0.03 GLN 182 -0.09 ASP 57

GLY 22 0.02 TRP 183 -0.10 ASP 57

VAL 95 0.02 LYS 184 -0.10 LYS 279

LYS 94 0.03 ARG 185 -0.10 LYS 279

GLY 35 0.03 SER 186 -0.11 LYS 279

GLY 35 0.03 SER 187 -0.11 ASP 57

GLY 208 0.05 VAL 188 -0.12 LYS 279

SER 206 0.08 GLU 189 -0.12 SER 51

SER 205 0.10 VAL 190 -0.13 SER 51

SER 205 0.14 GLY 191 -0.14 ASN 54

GLN 204 0.15 ASP 192 -0.16 PRO 140

VAL 203 0.12 THR 193 -0.15 VAL 53

VAL 203 0.13 ARG 194 -0.18 HIS 142

VAL 203 0.15 SER 195 -0.24 PRO 140

VAL 203 0.11 TRP 196 -0.18 VAL 53

ASP 199 0.10 ARG 197 -0.20 VAL 53

ASP 199 0.09 LEU 198 -0.19 LYS 279

SER 286 0.10 TYR 199 -0.20 LYS 279

SER 286 0.09 GLN 200 -0.21 ASN 275

ASP 199 0.07 PHE 201 -0.19 ASN 275

VAL 203 0.07 SER 202 -0.17 LYS 279

VAL 203 0.07 PHE 203 -0.16 LYS 279

GLN 204 0.07 VAL 204 -0.15 LYS 279

GLY 208 0.06 GLY 205 -0.14 LYS 279

GLY 208 0.05 LEU 206 -0.13 LYS 279

GLY 208 0.03 ARG 207 -0.12 HIS 56

GLY 35 0.02 ASN 208 -0.12 HIS 56

THR 126 0.02 THR 209 -0.11 HIS 56

LYS 106 0.02 THR 210 -0.10 ASP 57

LYS 106 0.03 GLU 211 -0.10 ASP 57

LYS 106 0.04 VAL 212 -0.09 ASP 57

LYS 106 0.05 VAL 213 -0.09 ASP 57

LYS 106 0.05 LYS 214 -0.07 ASP 57

LYS 106 0.06 THR 215 -0.07 ASP 57

LYS 106 0.07 THR 216 -0.06 ASP 57

LYS 106 0.06 SER 217 -0.05 ASP 57

LYS 106 0.05 GLY 218 -0.06 ASP 57

LYS 106 0.05 ASP 219 -0.07 ASP 57

LYS 106 0.05 TYR 220 -0.08 ASP 57

LYS 106 0.04 VAL 221 -0.09 ASP 57

LYS 106 0.04 VAL 222 -0.10 ASP 57

ARG 136 0.03 MET 223 -0.11 ASP 57

ARG 136 0.03 SER 224 -0.12 ASP 57

GLY 208 0.03 VAL 225 -0.13 ASP 57

VAL 203 0.04 TYR 226 -0.14 HIS 56

VAL 203 0.05 PHE 227 -0.15 HIS 56

VAL 203 0.05 ASP 228 -0.15 HIS 56

VAL 203 0.06 LEU 229 -0.16 ASN 275

VAL 203 0.06 SER 230 -0.18 ASN 275

ASP 199 0.07 ARG 231 -0.20 ASN 275

ASP 199 0.07 ARG 232 -0.18 ASN 275

ASP 199 0.07 MET 233 -0.19 ASN 275

SER 286 0.09 GLY 234 -0.19 ASN 275

ALA 281 0.14 TYR 235 -0.21 ASN 275

SER 286 0.11 PHE 236 -0.22 ASN 275

SER 286 0.08 THR 237 -0.21 SER 272

TYR 282 0.10 ILE 238 -0.22 ILE 271

SER 286 0.12 GLN 239 -0.24 ILE 271

TYR 220 0.09 THR 240 -0.26 SER 272

ILE 333 0.07 TYR 241 -0.22 SER 272

ILE 333 0.08 ILE 242 -0.21 THR 268

PRO 228 0.11 PRO 243 -0.24 THR 268

ILE 222 0.10 CYS 244 -0.25 THR 268

SER 329 0.08 THR 245 -0.22 LEU 264

SER 329 0.10 LEU 246 -0.22 LEU 264

LEU 231 0.13 ILE 247 -0.25 LEU 264

SER 329 0.11 VAL 248 -0.23 LEU 264

SER 329 0.10 VAL 249 -0.21 VAL 257

LEU 231 0.15 LEU 250 -0.23 VAL 257

LEU 231 0.15 SER 251 -0.27 VAL 257

PRO 325 0.12 TRP 252 -0.25 PRO 253

PRO 325 0.13 VAL 253 -0.26 PRO 253

VAL 238 0.16 SER 254 -0.31 PRO 253

ILE 322 0.14 PHE 255 -0.29 PRO 253

ILE 322 0.13 TRP 256 -0.28 LYS 312

VAL 238 0.17 ILE 257 -0.31 PRO 253

TRP 241 0.18 ASN 258 -0.34 LYS 312

TRP 241 0.20 LYS 259 -0.35 LYS 312

TRP 241 0.24 ASP 260 -0.41 LYS 312

ILE 242 0.28 ALA 261 -0.46 PRO 253

ILE 242 0.36 VAL 262 -0.51 PRO 253

ALA 249 0.38 PRO 263 -0.62 PRO 253

VAL 238 0.29 ALA 264 -0.47 PRO 253

VAL 238 0.29 ARG 265 -0.41 PRO 253

VAL 238 0.40 THR 266 -0.43 ALA 254

LEU 235 0.38 SER 267 -0.47 VAL 257

LEU 235 0.27 LEU 268 -0.36 VAL 257

LEU 235 0.29 GLY 269 -0.34 VAL 257

LEU 235 0.42 ILE 270 -0.38 VAL 257

LEU 235 0.31 THR 271 -0.39 THR 261

LEU 231 0.26 THR 272 -0.31 THR 261

LEU 231 0.33 VAL 273 -0.31 THR 261

PRO 228 0.37 LEU 274 -0.37 THR 265

PRO 228 0.28 THR 275 -0.35 THR 268

PRO 228 0.24 MET 276 -0.30 THR 268

PRO 228 0.31 THR 277 -0.32 THR 263

PRO 228 0.25 THR 278 -0.38 THR 268

ILE 271 0.20 LEU 279 -0.32 SER 272

GLN 224 0.19 SER 280 -0.29 SER 272

GLN 224 0.27 THR 281 -0.40 HIS 267

ASN 275 0.27 ILE 282 -0.37 SER 272

ASN 275 0.18 ALA 283 -0.30 SER 272

ASN 275 0.18 ARG 284 -0.30 HIS 267

ASN 275 0.24 LYS 285 -0.33 GLU 270

LYS 279 0.25 SER 286 -0.31 ASN 275

HIS 56 0.17 LEU 287 -0.28 THR 271

HIS 56 0.18 PRO 288 -0.29 THR 271

HIS 56 0.17 LYS 289 -0.34 THR 271

HIS 56 0.14 VAL 290 -0.27 THR 271

HIS 56 0.12 SER 291 -0.25 THR 271

HIS 56 0.10 TYR 292 -0.23 THR 271

HIS 56 0.09 VAL 293 -0.24 LEU 268

HIS 56 0.08 THR 294 -0.23 THR 271

HIS 56 0.07 ALA 295 -0.21 LEU 268

LYS 279 0.08 MET 296 -0.23 SER 272

HIS 56 0.10 ASP 297 -0.27 LEU 268

HIS 56 0.08 LEU 298 -0.24 LEU 268

HIS 56 0.07 PHE 299 -0.22 SER 272

GLY 219 0.09 VAL 300 -0.25 HIS 267

GLY 219 0.09 SER 301 -0.26 ILE 264

ILE 333 0.08 VAL 302 -0.23 THR 260

ILE 333 0.09 CYS 303 -0.23 THR 268

LEU 223 0.11 PHE 304 -0.27 THR 260

ILE 333 0.13 ILE 305 -0.24 THR 260

SER 329 0.11 PHE 306 -0.23 VAL 257

SER 329 0.12 VAL 307 -0.26 VAL 257

SER 329 0.15 PHE 308 -0.30 THR 256

SER 329 0.15 SER 309 -0.26 LEU 253

SER 329 0.14 ALA 310 -0.27 ALA 254

PRO 325 0.16 LEU 311 -0.33 ALA 252

PRO 325 0.19 VAL 312 -0.33 LEU 253

PRO 325 0.17 GLU 313 -0.27 SER 251

PRO 325 0.18 TYR 314 -0.32 SER 251

PRO 325 0.21 GLY 315 -0.41 ALA 249

ILE 322 0.21 THR 316 -0.33 ALA 249

ILE 322 0.19 LEU 317 -0.31 SER 251

ILE 322 0.21 HIS 318 -0.38 ALA 249

ILE 322 0.24 TYR 319 -0.37 ALA 246

ILE 322 0.20 PHE 320 -0.29 SER 251

ILE 322 0.18 VAL 321 -0.33 LYS 312

ILE 322 0.20 SER 322 -0.33 LYS 312

ILE 322 0.20 SER 323 -0.29 LYS 312

ILE 322 0.16 GLN 324 -0.29 LYS 312

ILE 322 0.15 PRO 325 -0.32 LYS 312

ILE 322 0.13 ALA 326 -0.29 LYS 312

ILE 322 0.14 ARG 327 -0.28 LYS 312

ILE 322 0.15 ALA 328 -0.30 LYS 312

ILE 322 0.14 ALA 329 -0.31 LYS 312

ILE 322 0.12 LYS 330 -0.28 LYS 312

ILE 322 0.13 MET 331 -0.28 LYS 312

ILE 322 0.13 ASP 332 -0.28 LYS 312

ILE 322 0.11 SER 333 -0.27 LYS 312

VAL 326 0.10 TYR 334 -0.25 LYS 312

VAL 326 0.10 ALA 335 -0.25 LYS 312

VAL 326 0.10 ARG 336 -0.25 LYS 312

VAL 326 0.08 ILE 337 -0.23 LYS 312

ILE 333 0.08 PHE 338 -0.23 LYS 312

SER 329 0.09 PHE 339 -0.23 LYS 312

ILE 333 0.07 PRO 340 -0.21 LYS 312

ILE 333 0.05 THR 341 -0.21 LYS 312

ILE 333 0.05 ALA 342 -0.21 LYS 312

ILE 333 0.06 PHE 343 -0.20 VAL 257

ILE 333 0.05 CYS 344 -0.19 LYS 312

ASP 199 0.05 LEU 345 -0.19 LYS 312

ASP 199 0.05 PHE 346 -0.18 LYS 312

ASP 199 0.05 ASN 347 -0.18 THR 268

ASP 199 0.05 LEU 348 -0.17 LYS 312

ASP 199 0.05 VAL 349 -0.17 THR 268

ASP 199 0.05 TYR 350 -0.18 SER 272

ASP 199 0.05 TRP 351 -0.18 SER 272

ASP 199 0.05 VAL 352 -0.16 SER 272

ASP 199 0.05 SER 353 -0.17 SER 272

ASP 199 0.05 TYR 354 -0.18 SER 272

ASP 199 0.05 LEU 355 -0.17 SER 272

ASP 199 0.04 TYR 356 -0.16 SER 272

ASP 199 0.05 LEU 357 -0.16 ASN 275

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** 6x3u ***

CA distance fluctuations for 2403121504002936075

--- normal mode 14 ---

Should you encounter any unexpected behaviour,
please let us know.

* 6x3u *