We are developing a computational method for automatically organizing
collections of structural knowledge of RNA into a three-dimensional (3-D)
form. The goal of our method for modeling of RNA structure is to find,
as much as possible, conformations of RNA which satisfy the constraints from
experiments and sequence analysis and, at the same time, whose local
conformations are close to some representative conformations.
For efficient conformational search, we used a genetic algorithm as a trial.
We applyed our method in modeling a single stranded region of an
RNA for the estimation of efficiency of our method.