Global climate change is particularly noticeable in the Arctic since it is warming twice as fast as temperate regions. The permanently frozen ground makes up 90% of Siberia so that the melting of permafrost reactivates microbial populations that contribute to the emission of greenhouse gases and the periodic resurgence of zoonotic diseases. In this work, published in the journal microLife, an international team shows that these permafrost microbes also constitute an enormous reservoir of antibiotic resistance genes.